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  3. Divaa-250 Tablet 15's

Divaa-250 Tablet 15's, Pack of 15 TABLETS
Divaa-250 Tablet 15's, Pack of 15 TABLETS
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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Divaa-250 Tablet is used to treat epilepsy (seizures/fits). It can be used alone or in combination with other medications to treat complex partial seizures that occur alone or alongside other types of seizures. It contains Divalproex sodium, which decreases the brain's excessive and abnormal nerve activity, thereby helping to control seizures. In some cases, it may cause common side effects such as drowsiness, dizziness, and nausea. Before taking this medicine, you should inform your doctor if you are allergic to any of its components, if you are pregnant/breastfeeding, and about all the medications you are taking, as well as any pre-existing medical conditions.

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Composition :

DIVALPROEX SODIUM-250MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Divaa-250 Tablet

Divaa-250 Tablet belongs to a group of medicines called anticonvulsants or antiepileptics, used to treat epilepsy (seizures/fits). It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

The name Divaa-250 Tablet contains 'Divalproex sodium,' which works by increasing the levels of a natural brain chemical called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, Divaa-250 Tablet helps control seizures.

Take Divaa-250 Tablet with or without food. You are advised to take Divaa-250 Tablet as prescribed by your doctor, depending on your medical condition. In some cases, you may experience certain common side effects, such as drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic to any of its contents, have significant liver disease or dysfunction, or have urea cycle disorders. Do not stop taking Divaa-250 Tablet without consulting your doctor, as this may worsen seizures. Avoid taking Divaa-250 Tablet if you are pregnant, as it may cause severe birth defects. Consult your doctor before using Divaa-250 Tablet if you are breastfeeding. Divaa-250 Tablet should be given to children only if prescribed by your doctor. Avoid driving or operating machinery, as Divaa-250 Tablet may cause drowsiness and dizziness. Avoid consuming alcohol along with Divaa-250 Tablet , as it could lead to increased dizziness.

Uses of Divaa-250 Tablet

Divaa-250 Tablet is used in the treatment of epilepsy (seizures). The detailed uses of Divaa-250 Tablet are as follows:
• It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.
• It may also be used alone or with other medications to treat both simple and complex absence seizures (which cause a brief loss and return of consciousness for a few seconds).

Directions for Use

  • Divaa-250 Tablet can be taken with or without food, or as advised by the doctor.
  • Shake the bottle well before each use.
  • Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided with the pack.
  • Replace the bottle cap tightly after each use.
  • Avoid using regular household spoons, as they may not accurately measure the dose.
  • Your doctor may adjust the dose and frequency of this medication based on your medical condition.

Medicinal Benefits

Divaa-250 Tablet belongs to a group of medicines called anticonvulsants or antiepileptics, primarily used to treat epilepsy (seizures or fits). It increases the levels of a natural chemical (GABA) in the brain, which helps reduce excessive and abnormal nerve activity in the brain, thereby helping to control seizures. Divaa-250 Tablet is used alone or in combination with other medications to treat complex partial seizures, whether they occur alone or alongside other types of seizures.

How Divaa-250 Tablet Works

Divaa-250 Tablet contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, Divaa-250 Tablet helps control seizures.

Storage

Store in a cool and dry place away from sunlight
Side effects of Divaa-250 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Brush and floss regularly twice a day with fluoride toothpaste and once a day with floss.
  • Use a soft or extra-soft toothbrush.
  • Avoid tobacco products, as smoking can worsen gum problems.
  • Use an antimicrobial mouthwash to reduce bacteria and prevent bleeding.
  • Drink green tea rich in catechin to reduce inflammation from oral bacteria.
  • Eat a balanced diet high in nutrients and low in sugar.
  • Reduce stress to minimize inflammation and gum bleeding.
  • Consult your dentist if gums bleed consistently.
  • Stretching and walking are examples of mild exercises that can improve mobility and reduce muscle stiffness.
  • Improving posture, mobility, and muscle coordination through physical therapy can help manage slowness or stiffness.
  • Maintain healthy weight and advance general health depend on eating a balanced diet.
  • Reducing symptoms like tremors or muscle spasms requires adequate sleep and rest.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Divaa-250 Tablet

Do not take more than the prescribed dose of Divaa-250 Tablet , as it may lead to an overdose. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you suspect you have taken an overdose or notice any of these symptoms, please consult a doctor immediately.

Drug Warnings

Do not take Divaa-250 Tablet if you are allergic to any of its contents, have significant liver disease or dysfunction, or have urea cycle disorders. Inform your doctor before taking Divaa-250 Tablet if you have pancreatitis, blood problems, or multi-organ hypersensitivity. Consult your doctor immediately if you experience suicidal tendencies while taking Divaa-250 Tablet . Divaa-250 Tablet may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature), and liver problems. Please do not stop taking Divaa-250 Tablet without consulting your doctor to avoid worsening of seizures. Do not take Divaa-250 Tablet if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking Divaa-250 Tablet . Consult your doctor before taking Divaa-250 Tablet if you are breastfeeding. Divaa-250 Tablet should be given to children only if prescribed by your doctor. Avoid driving or operating machinery, as Divaa-250 Tablet may cause drowsiness and dizziness. Avoid consuming alcohol along with Divaa-250 Tablet , as it could lead to increased drowsiness and dizziness.

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateVorinostat
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Divaa-250 Tablet:
Combining Sodium phenylbutyrate and Divaa-250 Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Divaa-250 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Divaa-250 Tablet:
Co-administration of Vorinostat with Divaa-250 Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Divaa-250 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Divaa-250 Tablet:
Co-administration of Divaa-250 Tablet with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Divaa-250 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Divaa-250 Tablet:
The combined use of Ertapenem and Divaa-250 Tablet can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Divaa-250 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Divaa-250 Tablet:
Using buprenorphine together with Divaa-250 Tablet may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Divaa-250 Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Divaa-250 Tablet:
Co-administration of Teriflunomide and Divaa-250 Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Divaa-250 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Divaa-250 Tablet:
Co-administration of Meropenam and Divaa-250 Tablet together can reduce the effect of Divaa-250 Tablet.

How to manage the interaction:
Co-administration of Meropenam and Divaa-250 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Divaa-250 Tablet:
Co-administration of Ketamine and Divaa-250 Tablet can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Divaa-250 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Divaa-250 Tablet:
Co-administration of Leflunomide and Divaa-250 Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Divaa-250 Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Divaa-250 Tablet:
Co-administration of Lithium with Divaa-250 Tablet can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Divaa-250 Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for energy generation of energy.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try to reduce or avoid them.
  • Please pay attention to your overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Divaa-250 Tablet Substitute

Substitutes safety advice

Product Substitutes

bannner image

Alcohol

Unsafe

Avoid consumption of alcohol while taking Divaa-250 Tablet , as it may cause increased drowsiness and dizziness.

bannner image

Pregnancy

Unsafe

Divaa-250 Tablet belongs to pregnancy category D. Avoid taking Divaa-250 Tablet if you are pregnant, as it could lead to serious birth defects. Consult your doctor for further advice.

bannner image

Breast Feeding

Caution

Divaa-250 Tablet may pass into breastmilk. Consult your doctor before taking Divaa-250 Tablet if you are breastfeeding.

bannner image

Driving

Unsafe

Divaa-250 Tablet causes drowsiness and dizziness. Therefore, do not drive or operate machinery until you are mentally alert.

bannner image

Liver

Unsafe

Divaa-250 Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Divaa-250 Tablet should be given to children only if prescribed by a doctor.

Have a query?

FAQs

Divaa-250 Tablet belongs to a group of medicines called anticonvulsants or antiepileptics, used to treat epilepsy (seizures/fits). It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.

Divaa-250 Tablet contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, Divaa-250 Tablet helps control seizures.

Do not discontinue Divaa-250 Tablet without consulting your doctor. To treat your condition effectively, continue taking Divaa-250 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Divaa-250 Tablet , your doctor will reduce the dose gradually to avoid worsening of seizures.

Divaa-250 Tablet may cause weight gain due to increased appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with Divaa-250 Tablet . Avoid getting pregnant while taking Divaa-250 Tablet as it could lead to severe birth defects. Do not stop taking Divaa-250 Tablet and consult your doctor immediately if you become pregnant.

Divaa-250 Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking Divaa-250 Tablet .

Topiramate (an anticonvulsant) should not be taken along with Divaa-250 Tablet as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature), and liver problems.

It is crucial to consult with your doctor before discontinuing Divaa-250 Tablet . Abruptly stopping this medication can lead to severe consequences, mainly if it's prescribed to treat conditions like epilepsy.

Divaa-250 Tablet can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, please consult your doctor.

Yes, Divaa-250 Tablet can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking Divaa-250 Tablet , it's essential to consult with your doctor.

Yes, Divaa-250 Tablet can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking Divaa-250 Tablet , seeking medical attention is crucial.

Avoid consumption of alcohol while taking Divaa-250 Tablet , as it may cause increased drowsiness and dizziness.

If you experience abdominal pain, nausea, and anorexia while taking Divaa-250 Tablet , it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.

An overdose of Divaa-250 Tablet can be a severe medical emergency. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you or someone you know has taken an overdose of Divaa-250 Tablet , please seek immediate medical attention.

The common side effects of Divaa-250 Tablet include drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - DIV0193

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Reference

  1. https://www.intaspharma.com/wp-content/uploads/2018/12/DIVAA.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018081s056lbl.pdf
  3. https://www.drugs.com/pro/valproic-acid-oral-solution.html
  4. https://medlineplus.gov/druginfo/meds/a682412.html
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