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compositionComposition:DOTHIEPIN-50MG
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Prescription Medicine
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DP 50 Tablet is used to treat depression and anxiety. It contains Dothiepin which works by increasing the levels of chemical messengers responsible for mood. In some cases, this medicine may cause side effects such as restlessness, irritability, tiredness, difficulty concentrating, and sleep disturbances. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DOTHIEPIN-50MG

Manufacturer/Marketer :

Depsons Pharma

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About DP 50 Tablet

DP 50 Tablet is an oral medicine containing dothiepin, a tricyclic antidepressant used to treat depression and, in some cases, anxiety associated with depressive illness. It helps restore the balance of certain brain chemicals that regulate mood, improving emotional well-being and making it easier for patients to carry out their daily activities.

To get the best results, you must take DP 50 Tablet consistently at the same time each day, usually in the evening. You can take this medication with or without food. Adopting healthy lifestyle changes, such as keeping a regular sleep schedule and eating a balanced diet, can also support your path to recovery.

Some people may experience mild side effects, like dry mouth or drowsiness, when first starting this treatment. However, if you experience serious side effects like a rapid heart rate, severe dizziness, or sudden mood changes, you must consult your doctor or seek medical help immediately.

Before starting this medicine, talk to your doctor if you have certain health conditions like heart problems, glaucoma, or difficulty urinating. Do not take this if you have recently had a heart attack. It is also not suitable for individuals with severe liver damage or untreated mania.

This medicine can interact with alcohol, causing increased drowsiness, and with other prescription drugs, which may lead to dangerous side effects. Always tell your healthcare provider about all medicines you are taking. If you are pregnant, breastfeeding, or elderly, you should consult your doctor before taking DP 50 Tablet to ensure it is safe for you.

Uses of DP 50 Tablet

DP 50 Tablet is used to treat depression and, in some cases, anxiety associated with depressive illness. The detailed uses of DP 50 Tablet are as follows:

  • Depression: It balances chemical messengers in the brain to relieve persistent sadness, low energy, and feelings of hopelessness.
  • Anxiety associated with depression: It helps calm feelings of nervousness, tension, and worry that frequently occur alongside depressive illnesses.
  • Insomnia associated with depression: It has a relaxing effect that helps improve sleep quality and makes it easier to fall asleep and stay asleep.

Key Benefits

DP 50 Tablet offers meaningful relief for people struggling with the overwhelming weight of depression. By restoring the natural balance of chemicals in your brain, this medicine helps you slowly regain your interest in daily activities and find joy in life again. Key benefits of using DP 50 Tablet include:

  • Improved Mood and Energy: It helps lift the fog of persistent sadness, giving you the physical and mental energy needed to manage your daily routine.
  • Better, Restful Sleep: Because of its gentle calming properties, it helps correct disrupted sleep patterns, allowing you to wake up feeling refreshed and ready for the day.
  • Reduced Anxiety and Tension: It eases the physical and emotional symptoms of anxiety, helping you feel more relaxed and less overwhelmed by daily stressors.
  • Gradual and Steady Recovery: Unlike short-term options, it provides stable, long-term support to help prevent your symptoms from returning.

Directions for Use

  • DP 50 Tablet can be taken with or without food, as advised by your doctor.
  • It is usually taken once daily at bedtime. However, your doctor may adjust the dose and duration of DP 50 Tablet based on your medical condition.
  • Swallow DP 50 Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How DP 50 Tablet Works

DP 50 Tablet contains dothiepin, which works by adjusting the levels of natural chemical messengers in the brain called neurotransmitters. Specifically, it targets serotonin and norepinephrine, which are responsible for regulating your mood, sleep, and emotional balance. In people with depression, these chemicals are often in low supply or are reabsorbed too quickly by the brain's nerve cells. DP 50 Tablet stops this rapid reabsorption, keeping a higher amount of serotonin and norepinephrine active in the brain. This continuous supply helps repair the chemical pathways, resulting in improved communication between brain cells and a gradual lifting of your mood.
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Alcohol

Unsafe

Do not consume alcohol while taking DP 50 Tablet as it may cause serious side effects.

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Pregnancy

Unsafe

DP 50 Tablet is not recommended for use in pregnancy. If you are pregnant, please inform your doctor before taking this medicine.

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Breast Feeding

Caution

DP 50 Tablet passes in very small amounts in breast milk. However, caution is advised while taking it. If you are breastfeeding, inform your doctor before taking this medicine.

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Driving

Unsafe

Do not drive vehicles or operate machines after taking DP 50 Tablet as it can make you feel drowsy.

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Liver

Caution

Limited information is available on the use of DP 50 Tablet in patients with liver disease. Hence, if you have liver problems, inform your doctor before taking this medicine.

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Kidney

Caution

Limited information is available on the use of DP 50 Tablet in patients with kidney disease. Hence, if you have kidney problems, inform your doctor before taking this medicine.

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Children

Unsafe

DP 50 Tablet is not recommended for use in children below 12 years.

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Heart

Unsafe

DP 50 Tablet is not recommended in cardiac patients due to its adverse effects. However, if prescribed extreme caution should be exercised.

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Geriatrics

Caution

DP 50 Tablet should be taken with caution in geriatric patients. Please consult your doctor before using DP 50 Tablet .

What if I have taken an overdose of DP 50 Tablet

If you or someone else takes too much of DP 50 Tablet , seek emergency medical care immediately. An overdose can cause serious complications, including rapid heartbeats, severe drowsiness, fits, or loss of consciousness.

Diet & Lifestyle Advise

  • Avoid drinking alcohol completely, as it can dangerously increase the drowsy effects of DP 50 Tablet and worsen your depression.
  • To manage or prevent constipation, drink plenty of water throughout the day and gradually add more fibre-rich foods like whole grains, vegetables, and fruits to your meals.
  • If you experience a dry mouth, try chewing sugar-free gum, sucking on ice chips, or keeping a water bottle nearby for frequent sips.
  • To prevent dizziness or lightheadedness, make a habit of standing up very slowly and carefully from sitting or lying down positions.
  • Maintain a strict sleep schedule by going to bed and waking up at the same times every day to help your body adapt to the relaxing effects of the medicine.
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How Soon It Starts Working

The time required for DP 50 Tablet to start to work: DP 50 Tablet ideally shows its action within 3 to 4 weeks after administration. The time for which the effects of DP 50 Tablet last: The effect of DP 50 Tablet lasts for 11 to 29 hours.

What if you forget to take DP 50 Tablet

If you miss a dose, take it as soon as you remember. If it is already close to the time for your next scheduled dose, skip the missed one and continue with your regular schedule. Never take two doses at the same time to make up for a missed dose. If you take your dose once daily at bedtime and miss it, do not take it the next morning; instead, contact your doctor or pharmacist for advice.

Storage

•Store DP 50 Tablet tablets or capsules at room temperature, ideally between 15°C and 25°C. •Keep it stored safely in a high cupboard or locked box, completely out of reach of children and pets.

Drug Warnings

  • This medicine can cause significant drowsiness and blurry vision; do not drive, ride a bicycle, or operate heavy machinery until you are certain you can do so safely.
  • Be patient when starting your treatment, as it can take up to 2 to 4 weeks of daily use before you begin to feel the full antidepressant benefits of DP 50 Tablet .
  • Do not stop taking DP 50 Tablet suddenly, as this can trigger unpleasant withdrawal symptoms such as nausea, headaches, and sleep troubles. Your doctor will help you by gradually decreasing the dose.
  • Let your dentist or surgeon know that you are taking this medicine before any surgery, as it can interact with drugs used for numbing or anaesthesia.
  • Avoid sudden exposure to hot weather or hot baths, as this medicine can affect how your body regulates temperature, making you more prone to overheating.

verifiedApollotooltip
  • Monoamine oxidase inhibitors (MAOIs): Do not take DP 50 Tablet if you are currently taking, or have taken within the past 14 days, an MAOI. Combining these medicines can cause a dangerous and rapid rise in blood pressure. Your doctor will advise you when it is safe to start treatment.
  • Medicines that cause drowsiness (e.g., sleeping pills, opioid pain relievers, antihistamines, or other antidepressants): Taking these medicines with DP 50 Tablet may significantly increase drowsiness, dizziness, impaired coordination, slowed breathing, and the risk of central nervous system (CNS) depression. Your doctor may recommend closer monitoring or dose adjustments.

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verifiedApollotooltip
  • Alcohol: Avoid drinking alcohol while taking DP 50 Tablet , as it can greatly increase drowsiness, impair coordination, and increase the risk of slowed or difficult breathing.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[PSYCHOTHERAPEUTICS]

FAQs

DP 50 Tablet is used to treat depression. It is also used to treat disorders related to anxiety.
No, DP 50 Tablet is not a muscle relaxant. It is a tricyclic antidepressant that is used for the treatment of depression and anxiety disorders.
DP 50 Tablet contains ‘Dothiepin’ that works by increasing the levels of chemical messengers responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. DP 50 Tablet helps improve your symptoms, such as elevating your mood and energy levels and improving sleep.
Based on your condition and symptoms, your doctor will advise the dose and duration of DP 50 Tablet . Discuss with your doctor if you have any concerns.
DP 50 Tablet is not recommended to treat pain. Rarely, it is advised to treat nerve pain like fibromyalgia or to prevent migraine.
No, DP 50 Tablet is not a habit-forming substance. However, it can cause irritability and difficulty sleeping, especially if you stop taking it abruptly.
DP 50 Tablet might cause weight gain as taking it makes you feel hungry. However, it varies from person to person, as some people might feel less hungry after taking it.
Always follow the instructions on the label or as directed by the physician for safe and effective use.
Both DP 50 Tablet and amitriptyline belong to the tricyclic antidepressant class used to treat symptoms of depression. However, do not replace the DP 50 Tablet with amitriptyline unless recommended by the doctor.
DP 50 Tablet and doxepin belong to tricyclic antidepressant class medications used to treat symptoms of depression. However, they may have different mechanisms of action. However, do not replace the DP 50 Tablet with doxepin unless recommended by the doctor.
You may take several weeks or longer to experience the full effect of DP 50 Tablet . Even if you are feeling good, continue to take DP 50 Tablet . Do not discontinue taking DP 50 Tablet without consulting your doctor. Before quitting, your doctor will most likely recommend that you gradually reduce your dose
DP 50 Tablet is associated with high mortality (death rate) in overdose. There is a low margin of safety between the maximum therapeutic dose and potentially fatal doses. So, you should strictly follow the dose and duration of DP 50 Tablet as directed by the physician. Do not overdose at any cost. If you feel you or someone overdosed or experience any severe adverse events with DP 50 Tablet , consult the doctor or go to the emergency room nearest hospital.
Caution should be exercised. The risk or severity of CNS depression can be increased when Diazepam is combined with DP 50 Tablet .
No. DP 50 Tablet is not intended to treat trigeminal neuralgia (sudden, severe facial pain. It's commonly described as a sudden shooting pain or as an electric shock to the jaw, teeth, or gums.).
No. $ name is not intended to treat burning mouth syndrome (a painful condition often described as a burning, scalding, or tingling feeling in the mouth that may occur every day for months).
Yes, DP 50 Tablet is intended to treat depression. However, it is a prescription medication and should be taken only if the doctor prescribes it to you.
No. DP 50 Tablet is not intended to treat IBS (irritable bowel syndrome). DP 50 Tablet is a tricyclic antidepressant medication used to treat depression.
It is not intended for insomnia with depression alone. However, your doctor may suggest DP 50 Tablet to treat insomnia with depression in some cases. Please consult your doctor for personalized guidance.
DP 50 Tablet can change the way your nerves receive pain signals. This can help with some kinds of nerve pain, including fibromyalgia. However, it should only be taken as prescribed by the doctor.
DP 50 Tablet is sometimes used to treat some types of nerve pain, such as fibromyalgia, or to prevent migraine. But it's not recommended or officially approved for pain relief.
No, you should avoid alcohol completely while taking this medicine. Alcohol can significantly increase the drowsiness and dizziness caused by DP 50 Tablet , and it can also make your depression worse. Talk to your doctor.
Feeling sleepy is a common side effect, especially when you first start taking the medicine. Taking your dose in the evening or at bedtime can help. Avoid driving or operating machinery if you feel drowsy. Talk to your doctor.
No, you should never stop taking this medicine suddenly on your own. Doing so can cause withdrawal symptoms like nausea, headaches, and irritability, and your depression could return. Your doctor will help you stop safely by gradually decreasing your dose. Talk to your doctor.
This medicine is generally not recommended during pregnancy or breastfeeding unless your doctor decides the benefits outweigh the risks. Taking it late in pregnancy may affect the newborn baby. Always talk to your doctor.
In some cases, this medicine can affect your heart rate or rhythm, especially if you already have a heart condition or are taking other medications. Your doctor may want to check your heart before or during your treatment. If you feel a fast or irregular heartbeat, talk to your doctor.

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Country of origin

India
Other Info - DP50001
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