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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Draminate 50 mg Tablet is used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. Besides this, it is also used to treat nausea and vomiting associated with radiation sickness, surgery, and drug-induced Meniere disease (feelings of spinning and inner ear problems). Draminate 50 mg Tablet contains Dimenhydrinate, which relieves motion sickness by blocking histamine and muscarinic receptors that trigger nausea, vomiting, and dizziness. Common side effects of Draminate 50 mg Tablet may include dry mouth, blurred vision, drowsiness, dizziness, headache, fatigue, disorientation, tinnitus, palpitations, and low blood pressure. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Whats That

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Composition :

DIMENHYDRINATE-50MG

Manufacturer/Marketer :

RPG Life Sciences Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Draminate 50 mg Tablet

Draminate 50 mg Tablet is used to prevent and treat nausea (feeling sick), vomiting (being sick), and dizziness caused by motion sickness. Besides this, it is also used to treat nausea and vomiting associated with radiation sickness, surgery, and drug-induced Meniere disease (feelings of spinning and inner ear problems). Motion sickness is an illness caused by motion during travel, characterised by nausea and vomiting.

Draminate 50 mg Tablet contains Dimenhydrinate, which acts as both an antihistamine and an anticholinergic. It works by blocking histamine (H₁) receptors and muscarinic (M₁) receptors in the brain areas that control balance and nausea. This helps reduce the signals that cause motion sickness, leading to relief from nausea, vomiting, and dizziness.

Draminate 50 mg Tablet may cause side effects such as dry mouth, blurred vision, drowsiness, dizziness, headache, tiredness, disorientation, tinnitus, palpitations, and low blood pressure (hypotension). Most of these side effects do not require medical attention and resolve gradually over time. However, seek medical attention immediately if these side effects persist or worsen.

Notify your doctor if you have breathing problems (asthma, emphysema), high pressure in the eye (glaucoma), seizures (fits), liver, kidney, heart problems, chronic obstructive pulmonary disease (COPD), or sleep apnea (sleeping disorder). Consult your doctor if you are pregnant or breastfeeding. Draminate 50 mg Tablet should not be given to children below 2 years as the safety and effectiveness have not been established. Draminate 50 mg Tablet may cause dizziness, so drive or operate heavy machinery only if you are alert.

Uses of Draminate 50 mg Tablet

Draminate 50 mg Tablet is used in the treatment of motion sickness. The detailed uses of Draminate 50 mg Tablet are as follows:<br/> • Motion Sickness Relief: Draminate 50 mg Tablet is effectively used to prevent and treat symptoms of motion sickness, including nausea, vomiting, and dizziness during travel by car, plane, or boat.<br/> • Nausea and Vomiting: Draminate 50 mg Tablet can be used to alleviate nausea and vomiting that may occur due to other conditions, such as migraine headaches or certain gastrointestinal disorders.<br/> • Postoperative Nausea: Draminate 50 mg Tablet is often administered to reduce nausea and vomiting after surgical procedures due to anesthesia.<br/> • Vertigo Management: Draminate 50 mg Tablet can help manage vertigo symptoms, which are often associated with inner ear disorders.<br/>

Directions for Use

  • Draminate 50 mg Tablet can be taken with or without food.
  • Take the first dose 30 to 60 minutes before travelling or starting any motion-related activity if using it for motion sickness.
  • It is typically administered every 4-6 hours as needed, or as directed by your doctor.
  • Swallow Draminate 50 mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break the medication.

Medicinal Benefits

Draminate 50 mg Tablet contains Dimenhydrinate, which helps prevent and treat nausea, vomiting, and dizziness caused by motion sickness, vertigo, radiation sickness, surgery, and drug-induced Meniere’s disease by calming the brain areas that control balance and nausea.

How Draminate 50 mg Tablet Works

Draminate 50 mg Tablet contains Dimenhydrinate, which acts as both an antihistamine and an anticholinergic. It works by blocking histamine (H₁) receptors and muscarinic (M₁) receptors in the brain areas that control balance and nausea. This helps reduce the signals that cause motion sickness, leading to relief from nausea, vomiting, and dizziness.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Draminate 50 mg Tablet

Do not take more than the prescribed dose of Draminate 50 mg Tablet , as it may cause an overdose. Symptoms of an overdose include large pupils, drowsiness, hallucinations, excitation, confusion, or seizures (fits). If you suspect you have taken an overdose or notice any of these symptoms, please consult a doctor immediately.

Drug Warnings

Do not take Draminate 50 mg Tablet if you are allergic to any of its contents. Before taking Draminate 50 mg Tablet , please tell your doctor if you are using any antidepressants. Draminate 50 mg Tablet is not intended for prolonged use unless prescribed by a physician. Inform your doctor if you are pregnant or breastfeeding. Antihistamine overdosage may cause hallucinations, convulsions, or death, especially in infants and children; it also produces excitation in younger children. So, dose adjustments may be necessary if prescribed to children. Draminate 50 mg Tablet should not be given to children below 2 years of age and patients who are unconscious or have severe drowsiness, dizziness, or headache. Inform your doctor if you have difficulty breathing, asthma or bronchitis (lung problems), epilepsy (fits), severe heart problems, liver or kidney problems, a stomach blockage, hearing problems, or increased pressure in the eye (glaucoma).

Drug-Drug Interactions

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DimenhydrinatePotassium citrate
Critical

Drug-Drug Interactions

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DimenhydrinatePotassium citrate
Critical
How does the drug interact with Draminate 50 mg Tablet:
Co-administration of Draminate 50 mg Tablet and Potassium citrate can increase the risk of developing stomach inflammation.

How to manage the interaction:
Taking Draminate 50 mg Tablet with Potassium citrate is generally avoided, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, sudden lightheadedness, vomiting (especially with blood), or tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Draminate 50 mg Tablet:
Co-administration of Draminate 50 mg Tablet and Potassium chloride can increase the risk of stomach inflammation.

How to manage the interaction:
Co-administration of Draminate 50 mg Tablet with Potassium chloride is generally not recommended, as it can lead to an interaction, it can be taken when a doctor has prescribed it. However, if you experience severe stomach pain, sudden dizziness, vomiting (especially with blood), or dark stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Draminate 50 mg Tablet:
The combined use of ketamine and Draminate 50 mg Tablet can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of ketamine and Draminate 50 mg Tablet can lead to an interaction, but it can be taken if advised by your doctor. however contact your doctor if you experience any side effects such as dizziness, confusion, difficulty concentrating, or shortness of breath. Do not stop using any medications without a doctor's advice.
How does the drug interact with Draminate 50 mg Tablet:
Coadministration of Draminate 50 mg Tablet with Zonisamide can increase the risk or severity of Zonisamide side effects.

How to manage the interaction:
Taking Draminate 50 mg Tablet with Zonisamide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience shortness of breath, palpitations, fever, or excessive sweating, contact a doctor. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
DimenhydrinateSodium oxybate
Severe
How does the drug interact with Draminate 50 mg Tablet:
Using Draminate 50 mg Tablet and sodium oxybate together can increase the risk of side effects.

How to manage the interaction:
Co-administration of Draminate 50 mg Tablet and sodium oxybate can lead to an interaction, it can be taken if your doctor advises. however contact your doctor if you experience dizziness, confusion, difficulty concentrating, breathing difficulty, or palpitations. Do not stop using any medications without a doctor's advice.
How does the drug interact with Draminate 50 mg Tablet:
Coadministration of Draminate 50 mg Tablet with topiramate can increase the risk of topiramate side effects.

How to manage the interaction:
Taking Draminate 50 mg Tablet with topiramate is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience decreased sweating, fever, dizziness, or shortness of breath, contact your doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting your doctor.
DimenhydrinateEsketamine
Severe
How does the drug interact with Draminate 50 mg Tablet:
Co-administration of Esketamine and Draminate 50 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Co-administration of esketamine and Draminate 50 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. Consult a doctor if you experience drowsiness, confusion, shortness of breath, or palpitations. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • ​​​​​​Avoid spicy, greasy, and acidic foods before travelling; it may increase the feeling of sickness.
  • Opt for cereals, apples, bananas, or bread.
  • Breathe the fresh air, if possible, by opening the window.
  • In many cases, a full stomach and excessive heat may worsen the symptoms of motion sickness, so space out your meals and eat light.
  • Position yourself where motion is least, like in the front seat of a car, the centre of a boat or ship.
  • Avoid alcohol 24 hours before travel and during travel.

Habit Forming

No

Therapeutic Class

ANTIHISTAMINE

Draminate 50 mg Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

Avoid alcohol consumption while taking Draminate 50 mg Tablet , as it may cause increased drowsiness.

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Pregnancy

Caution

Draminate 50 mg Tablet is a pregnancy category B drug. Please consult your doctor before taking Draminate 50 mg Tablet if you are pregnant or planning to become pregnant. Your doctor will weigh the benefits and any potential risks before prescribing Draminate 50 mg Tablet .

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Breast Feeding

Caution

It is not known whether Draminate 50 mg Tablet passes into breast milk or harms a nursing baby. Please consult your doctor before taking Draminate 50 mg Tablet if you are breastfeeding.

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Driving

Caution

Draminate 50 mg Tablet may cause drowsiness and dizziness. So, avoid driving or operating heavy machinery while using Draminate 50 mg Tablet .

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Liver

Caution

Draminate 50 mg Tablet should be used with caution in patients with liver diseases. Please consult your doctor before taking Draminate 50 mg Tablet . Your doctor will weigh the benefits and any potential risks before prescribing Draminate 50 mg Tablet .

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Kidney

Caution

Draminate 50 mg Tablet should be used with caution in patients with kidney diseases. Please consult your doctor before taking Draminate 50 mg Tablet . Your doctor will weigh the benefits and any potential risks before prescribing Draminate 50 mg Tablet .

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Children

Caution

Draminate 50 mg Tablet is not recommended for use in children below 2 years of age. For children above 2 years of age, dose adjustments may be necessary if prescribed.

Have a query?

FAQs

Draminate 50 mg Tablet is used to prevent and treat nausea (feeling sick), vomiting (being sick), and dizziness caused by motion sickness. Besides this, it is also used to treat nausea and vomiting associated with radiation sickness, surgery, and drug-induced Meniere disease (feelings of spinning and inner ear problems).

Draminate 50 mg Tablet contains Dimenhydrinate, which acts as both an antihistamine and an anticholinergic. It works by blocking histamine (H₁) receptors and muscarinic (M₁) receptors in the brain areas responsible for balance and nausea. This action helps reduce signals that lead to motion sickness, providing relief from nausea, vomiting, and dizziness.

Yes, the use of Draminate 50 mg Tablet can cause dry mouth. If you feel excessively thirsty, increase your fluid intake and avoid consuming spicy and salty foods.

Draminate 50 mg Tablet is an anti-sickness medication that takes approximately 30-60 minutes to take effect.

Draminate 50 mg Tablet is usually recommended for short-term use. Do not take longer than prescribed unless advised by your doctor.

Draminate 50 mg Tablet is generally safe if used as per the prescribed dose and duration. It's important to follow your doctor's instructions.

Draminate 50 mg Tablet is generally not addictive when used as prescribed by your doctor. However, it’s important to follow your doctor's instructions to avoid any potential misuse.

No, using Draminate 50 mg Tablet together with Cymbalta (which contains Duloxetine) may increase the risk of side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. However, consult your doctor if you have any concerns.

Yes, Draminate 50 mg Tablet can cause drowsiness or tiredness as side effects. It's important to be cautious when taking this medication, especially if you need to drive, operate machinery, or perform tasks that require alertness. If you experience excessive drowsiness or tiredness, it's best to avoid such activities.

Yes, Draminate 50 mg Tablet has the ability to increase the sedative effects of opiates. Therefore, it's important to use them carefully and under your doctor's supervision because taking them together could increase sleepiness and other sedative effects.

No, Draminate 50 mg Tablet does not contain aspirin. The active ingredient in Draminate 50 mg Tablet is dimenhydrinate, which is an antihistamine used to treat motion sickness, nausea, and vomiting.

The common side effects of Draminate 50 mg Tablet are dry mouth, blurred vision, drowsiness, dizziness, headache, tiredness, disorientation, tinnitus, palpitation, and low blood pressure (hypotension). Most of these side effects do not require medical attention and resolve gradually over time. However, seek medical attention immediately if these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA
Other Info - DRA0005

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