Entimate 0.5 Tablet 30's

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Prescription Medicine

Entimate 0.5 Tablet 30's is used to treat chronic hepatitis B virus (HBV) infection. It helps reduce the amount of virus in the body, prevents further liver damage, and supports long-term liver health. With regular use, it lowers the risk of complications such as cirrhosis and liver failure, helping to slow the progression of liver disease.

Written By Veda Maddala , M Pharmacy

Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

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More about the Product

Composition :

ENTECAVIR-0.5MG

Manufacturer/Marketer :

RSL Bioscience Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Entimate 0.5 Tablet 30's

Entimate 0.5 Tablet 30's is used to treat chronic hepatitis B virus (HBV) infection. Hepatitis B is a severe liver infection caused by the hepatitis B virus (HBV). It is highly contagious and spreads through intimate contact with the infected person and direct contact with infected blood.

Entimate 0.5 Tablet 30's contains Entecavir, which helps prevent the virus from replicating and reduces the amount of hepatitis B virus in the body.

Take Entimate 0.5 Tablet 30's as advised by the doctor. In some cases, you may experience dizziness, headache, nausea, vomiting, drowsiness, extreme tiredness, inability to sleep, diarrhoea, or indigestion. Most of these side effects do not require medical attention. However, if the side effects worsen, please consult your doctor.

If you are allergic to Entimate 0.5 Tablet 30's or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please consult a doctor before taking Entimate 0.5 Tablet 30's. It is recommended to use effective contraceptive methods while using Entimate 0.5 Tablet 30's to avoid pregnancy. If you have HIV/AIDS, kidney or liver problems, inform your doctor before taking Entimate 0.5 Tablet 30's.

Uses of Entimate 0.5 Tablet 30's

Entimate 0.5 Tablet 30's is used in the treatment of chronic (long-term) hepatitis B virus (HBV) infection. The detailed uses of Entimate 0.5 Tablet 30's are as follows:

Treatment of Chronic HBV Infection: Entimate 0.5 Tablet 30's is indicated for the treatment of chronic HBV infection, including those with compensated liver disease (liver is damaged but still functions properly) and decompensated liver disease (liver is damaged and no longer functions properly).

Have a query?

Directions for Use

Entimate 0.5 Tablet 30's can be taken on an empty stomach, preferably 2 hours before or after a meal.
It is usually taken once daily at the same time each day or as prescribed by your doctor.
Swallow Entimate 0.5 Tablet 30's as a whole with a glass of water.
Do not break, crush, or chew it.

Key Benefits

Effectively inhibits the growth of the hepatitis B virus (HBV).
Lowers ALT/AST levels and liver inflammation.
Inhibits or slows the development of cirrhosis.
Reduces the chance of hepatocellular carcinoma (liver cancer) and liver failure.
Enhances liver health over the long run with ongoing treatment.

How Entimate 0.5 Tablet 30's Works

Entimate 0.5 Tablet 30's contains Entecavir, an antiviral drug. It works by inhibiting viral DNA polymerase enzyme action in the liver cells, which is essential for the virus to multiply. Therefore, it prevents the virus from replicating and reduces the amount of hepatitis B virus in the body.

Storage

Store in a cool and dry place away from sunlight

Side effects of Entimate 0.5 Tablet

Trouble Falling/ Staying Asleep

Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:

Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
Try relaxing techniques like deep breathing, mindfulness meditation and any others.
Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.

Drowsiness

Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Loose/ Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Indigestion

Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:

Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Increased liver enzymes

What if I have taken an overdose of Entimate 0.5 Tablet 30's

An overdose of Entimate 0.5 Tablet 30's may cause unpleasant effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

If you are allergic to Entimate 0.5 Tablet 30's or any other medicines, please tell your doctor.
If you are pregnant or breastfeeding, please consult a doctor before taking Entimate 0.5 Tablet 30's.
It is recommended to use effective contraceptive methods while using Entimate 0.5 Tablet 30's to avoid pregnancy.
Entimate 0.5 Tablet 30's is not recommended for children below 2 years of age.
Inform your doctor if you experience stomach pain, vomiting or nausea while taking Entimate 0.5 Tablet 30's, as it might indicate the development of lactic acidosis (excess of lactic acid in blood), a rare but serious side effect.
If you have HIV/AIDS or kidney or liver problems, inform your doctor before taking Entimate 0.5 Tablet 30's.

Drug-Drug Interactions

EntecavirCiprofloxacin

Severe

EntecavirAllopurinol

Severe

Drug-Drug Interactions

EntecavirCiprofloxacin

Severe

How does the drug interact with Entimate 0.5 Tablet:
Combining Entimate 0.5 Tablet with ciprofloxacin may result in higher blood levels of one or both the medications.

How to manage the interaction:
Although taking ciprofloxacin and Entimate 0.5 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. If your situation changes or you start to notice more side effects, consult your doctor.

EntecavirAllopurinol

Severe

How does the drug interact with Entimate 0.5 Tablet:
Coadministration of Allopurinol with Entimate 0.5 Tablet may increase the blood levels of one or both medicines and increase side effects.

How to manage the interaction:
If you are supposed to take Allopurinol and Entimate 0.5 Tablet together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience increased side effects, contact your doctor.

EntecavirMethotrexate

Severe

How does the drug interact with Entimate 0.5 Tablet:
The combined use of Entimate 0.5 Tablet with methotrexate may increase levels of Entimate 0.5 Tablet, and increase the risk or severity of kidney damage.

How to manage the interaction:
Although there is a possible interaction between Entimate 0.5 Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult a doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Diet & Lifestyle Advise

Healthy eating habits:

Eat a liver-friendly, well-balanced diet rich in fruits, vegetables, and healthy grains.
Reduce liver strain by limiting processed, fried, and fatty foods.
Eat meals at regular times and drink plenty of water.

Lifestyle changes:

Avoid alcohol entirely to safeguard your liver.
Maintain a healthy weight by engaging in moderate exercise.

Physical activity

Regularly engage in light to moderate exercise, such as yoga or walking.
Steer clear of overdoing it if you're feeling weak or exhausted.
To lessen liver strain, maintain a healthy weight.

Habit Forming

Therapeutic Class

[ANTIVIRALS]

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Alcohol

Consult your doctor

The interaction of alcohol with Entimate 0.5 Tablet 30's is unknown. Please consult a doctor before consuming alcohol while using Entimate 0.5 Tablet 30's.

Pregnancy

Caution

Entimate 0.5 Tablet 30's is a category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

Breast Feeding

Consult your doctor

It is unknown whether Entimate 0.5 Tablet 30's is excreted in human milk. Therefore, please consult a doctor if you are breastfeeding.

Driving

Caution

Entimate 0.5 Tablet 30's may cause dizziness, drowsiness or tiredness in some people. Therefore, avoid driving or operating heavy machinery if you feel dizzy, drowsy or tired after taking Entimate 0.5 Tablet 30's.

Liver

Caution

Take Entimate 0.5 Tablet 30's with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required. Please consult a doctor.

Kidney

Caution

Take Entimate 0.5 Tablet 30's with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required. Please consult a doctor.

Children

Caution

Entimate 0.5 Tablet 30's is not recommended for children below 2 years or weighing less than 10 kg. However, in children above 2 years, Entimate 0.5 Tablet 30's should be used with caution and doses prescribed by a doctor.

Heart

Safe if prescribed

Entimate 0.5 Tablet 30's is safe for use in heart patients if recommended by the physician.

Geriatrics

Caution

Entimate 0.5 Tablet 30's should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Entimate 0.5 Tablet 30's.

FAQs

What is the use of Entimate 0.5 Tablet 30's?

Entimate 0.5 Tablet 30's is used to treat chronic hepatitis B virus (HBV) infection.

How does Entimate 0.5 Tablet 30's work?

Entimate 0.5 Tablet 30's contains Entecavir, an antiviral drug that works by preventing viral DNA polymerase enzyme action in the liver cells, which is essential for the virus to multiply. Therefore, it prevents the virus from replicating and reduces the amount of hepatitis B virus in the body.

Is hepatitis B virus infection contagious?

Yes, hepatitis B virus infection is highly contagious and spreads from one person to another. Therefore, it is recommended to avoid sharing personal items or needles containing an infected person's blood or body fluids.

Does Entimate 0.5 Tablet 30's cause lactic acidosis?

Entimate 0.5 Tablet 30's may cause lactic acidosis (excess of lactic acid in the blood), a rare but severe side effect, especially in women who are very obese. However, if you experience stomach pain, vomiting or nausea while taking Entimate 0.5 Tablet 30's, please consult a doctor immediately.

Can I take Entimate 0.5 Tablet 30's with celecoxib?

You are not recommended to take Entimate 0.5 Tablet 30's with celecoxib (painkiller), as it may increase the blood levels of Entimate 0.5 Tablet 30's, leading to more adverse effects and may also affect kidney function. However, please consult your doctor before taking Entimate 0.5 Tablet 30's with other medicines.

Does Entimate 0.5 Tablet 30's cure hepatitis B virus infection?

Entimate 0.5 Tablet 30's does not cure hepatitis B virus infection. Entimate 0.5 Tablet 30's reduces the amount of hepatitis B virus in the body and improves liver functioning by decreasing liver damage.

Is Entimate 0.5 Tablet 30's safe for patients with HIV infection?

Entimate 0.5 Tablet 30's is not recommended for hepatitis B patients with HIV infection unless they are taking medicines to treat HIV infection at the same time, as Entimate 0.5 Tablet 30's may cause HIV infection to become resistant to certain HIV drugs and reduce their effectiveness. Therefore, it is advised to get tested for HIV infection before taking Entimate 0.5 Tablet 30's.

Can I stop taking Entimate 0.5 Tablet 30's on my own?

You are not recommended to stop taking Entimate 0.5 Tablet 30's without consulting your doctor, as it may worsen the infection or cause recurring symptoms. Therefore, take Entimate 0.5 Tablet 30's for as long as your doctor has prescribed it. If you experience any difficulty while taking Entimate 0.5 Tablet 30's, please consult your doctor.

What are the side effects of Entimate 0.5 Tablet 30's?

Entimate 0.5 Tablet 30's may cause side effects like dizziness, headache, nausea, vomiting, drowsiness, extreme tiredness, inability to sleep, diarrhoea, or indigestion. Most of these side effects do not require medical attention. However, if the side effects worsen, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

B-57, First Floor, Amar Colony, Nangloi, New Delhi-110041.India

Other Info - ENT0215

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Author Details

Written By

Veda Maddala

M Pharmacy

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Feb 6, 2026 | 11:07 AM IST

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