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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Evoxil-HP Kit Tablet 1's is used in the treatment of peptic ulcer disease caused by infection with a common type of bacteria called Helicobacter pylori (H. pylori). It kills bacteria or prevents their growth. Also, it reduces the amount of acid produced in the stomach. It may cause common side effects, such as nausea, diarrhoea, vomiting, stomach pain, taste change, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Leeford Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Evoxil-HP Kit Tablet 1's

Evoxil-HP Kit Tablet 1's is used in the treatment of peptic ulcer disease caused by infection with a common type of bacteria called Helicobacter pylori (H. pylori). Peptic ulcers are sores (small, shallow wounds) that develop on the intestine and stomach's inner lining.

Evoxil-HP Kit Tablet 1's is a combination of three drugs, namely: Pantoprazole, amoxycillin, and clarithromycin. Amoxycillin works by preventing the formation of bacterial cell covering (protective cell wall) necessary for their survival, thereby preventing the growth of bacteria. Clarithromycin stops bacterial growth but does not necessarily kill them. Pantoprazole reduces the amount of acid produced in the stomach. Altogether, Evoxil-HP Kit Tablet 1's helps treat peptic ulcer disease.

In some cases, you may experience certain common side effects, such as nausea, diarrhoea, vomiting, stomach pain, taste change, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Evoxil-HP Kit Tablet 1's if you are pregnant or breastfeeding unless prescribed by the doctor. Evoxil-HP Kit Tablet 1's causes drowsiness, so drive only if you are alert. Evoxil-HP Kit Tablet 1's should not be given to children as safety has not been established. Avoid consuming alcohol along with Evoxil-HP Kit Tablet 1's as it could lead to increased drowsiness and can elevate the production of stomach acid.

Uses of Evoxil-HP Kit Tablet 1's

Evoxil-HP Kit Tablet 1's is used in the treatment of Peptic ulcer disease. The detailed uses of Evoxil-HP Kit Tablet 1's are as follows:

  • Treat peptic ulcers caused by H. pylori infection: Evoxil-HP Kit Tablet 1's is primarily used to eradicate Helicobacter pylori, a bacterium responsible for stomach and intestinal ulcers. Amoxycillin and Clarithromycin are antibiotics that kill or inhibit bacterial growth, while Pantoprazole reduces stomach acid to promote healing.
  • Manage acid-related gastrointestinal disorders: Evoxil-HP Kit Tablet 1's helps relieve symptoms of acid reflux, heartburn, and gastritis by lowering gastric acid production. This creates a less acidic environment, allowing ulcers and inflamed tissues to recover.
  • Prevent recurrence of ulcers and complications: Evoxil-HP Kit Tablet 1's is also used to prevent the return of ulcers and reduce the risk of gastrointestinal bleeding or perforation. Its combination action approach ensures both bacterial eradication and mucosal protection.

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Directions for Use

  • Take Evoxil-HP Kit Tablet 1's 30-60 minutes before food as advised by your doctor.
  • It is advised to take Evoxil-HP Kit Tablet 1's as directed by your doctor, at the same time each day for best results.
  • Swallow Evoxil-HP Kit Tablet 1's as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Evoxil-HP Kit Tablet 1's effectively treats Helicobacter pylori (H. pylori) infection in the stomach.
  • Helps heal and prevent recurrence of peptic ulcers and gastric or duodenal ulcers.
  • Pantoprazole reduces stomach acid production, creating a favourable environment for ulcer healing.
  • Amoxycillin and clarithromycin work together to eliminate the H. pylori bacteria causing infection.
  • Reduces symptoms such as heartburn, acidity, stomach pain, bloating, and indigestion.
  • Offers a triple therapy approach for complete eradication of the infection.
  • Improves digestive comfort and promotes long-term gastrointestinal health.

How Evoxil-HP Kit Tablet 1's Works

Evoxil-HP Kit Tablet 1's is a combination of three drugs, namely: Pantoprazole, amoxycillin, and clarithromycin. Amoxycillin is bactericidal (kills bacteria) and works by preventing the formation of the bacterial cell wall (protective cell wall) necessary for their survival, thereby preventing bacterial growth. Clarithromycin is a bacteriostatic antibiotic; i.e., it stops bacterial growth but does not necessarily kill them. It works by inhibiting the protein synthesis required for bacterial cell growth. As a result, bacterial cells cannot reproduce or grow. Pantoprazole is a proton pump inhibitor that works by blocking the action of an enzyme called the gastric proton pump, which is responsible for the production of acid in the stomach. Thereby reduces the amount of acid produced in the stomach. Altogether, Evoxil-HP Kit Tablet 1's helps treat peptic ulcer disease.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Evoxil-HP Kit Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth or herbal tea to soothe sore throat.
  • Gargle with warm salt water to decrease inflammation.
  • Suck on hard candies or lozenges to increase the production of saliva and soothe your throat.
  • Avoid smoking, spicy foods, and extremely hot fluids.
  • Rest your voice and get enough sleep.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Bitter or bad taste can be managed by taking Vitamin B12 supplements only after your doctor's consultation.
  • Maintain good oral hygiene by using mouthwash frequently and cleaning your tongue while brushing.
  • Avoid eating foods that cause heartburn or stomach pain, as they can lead to a bitter taste in your mouth.
  • Do not smoke or drink alcohol, as it can worsen your condition.

What if I have taken an overdose of Evoxil-HP Kit Tablet 1's

Do not take more than the prescribed dose of Evoxil-HP Kit Tablet 1's as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Inform your doctor before taking Evoxil-HP Kit Tablet 1's if you have a history of liver disease, kidney disease, or myasthenia gravis (neuromuscular disease).
  • Do not take Evoxil-HP Kit Tablet 1's if you are pregnant or breastfeeding unless prescribed by the doctor.
  • Evoxil-HP Kit Tablet 1's causes drowsiness, so drive only if you are alert.
  • Evoxil-HP Kit Tablet 1's should not be given to children as safety has not been established.
  • Avoid consuming alcohol along with Evoxil-HP Kit Tablet 1's as it could lead to increased drowsiness and can elevate the production of stomach acid.
  • Keep your doctor informed about all the medicines and your health condition to rule out any side effects.

Drug-Drug Interactions

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ClarithromycinDroperidol
Critical

Drug-Drug Interactions

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How does the drug interact with Evoxil-HP Kit Tablet:
Taking Rifabutin and Evoxil-HP Kit Tablet together may increase the blood levels of rifabutin.

How to manage the interaction:
Taking Rifabutin with Evoxil-HP Kit Tablet is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately If you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
ClarithromycinDroperidol
Critical
How does the drug interact with Evoxil-HP Kit Tablet:
Co-administration of Droperidol with Evoxil-HP Kit Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Evoxil-HP Kit Tablet with Droperidol can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Evoxil-HP Kit Tablet:
Combining Evoxil-HP Kit Tablet with Thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Evoxil-HP Kit Tablet and Thioridazine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Evoxil-HP Kit Tablet:
When Ranolazine and Evoxil-HP Kit Tablet are taken together, significantly increases the blood levels and effects of Ranolazine.

How to manage the interaction:
Co-administration of Evoxil-HP Kit Tablet and Ranozaline can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
Critical
How does the drug interact with Evoxil-HP Kit Tablet:
When Naloxegol is taken with Evoxil-HP Kit Tablet, the amount of Naloxegol in the blood can go up.

How to manage the interaction:
Co-administration of Evoxil-HP Kit Tablet and Naloxegol can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sweating, tearing, runny nose, chills, diarrhea, abdominal pain, anxiety, insomnia, irritability, restlessness, and yawning, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Evoxil-HP Kit Tablet:
When Dronedarone is taken with Evoxil-HP Kit Tablet, can increase the blood levels of dronedarone and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Evoxil-HP Kit Tablet with Dronedarone can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinSaquinavir
Critical
How does the drug interact with Evoxil-HP Kit Tablet:
When Evoxil-HP Kit Tablet is taken with Saquinavir, increases the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Evoxil-HP Kit Tablet and Saquinavir can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Evoxil-HP Kit Tablet:
Co-administration of Eplerenone and Evoxil-HP Kit Tablet may significantly increase the blood levels and effects of eplerenone.This may increase the risk or severity of side effects like high blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking Evoxil-HP Kit Tablet with Eplerenone is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the Doctor's advice.
How does the drug interact with Evoxil-HP Kit Tablet:
Using Lurasidone together with Evoxil-HP Kit Tablet may result in significantly higher Lurasidone blood levels. This may increase the possibility of side effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Lurasidone and Evoxil-HP Kit Tablet may interact, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Evoxil-HP Kit Tablet:
Taking Evoxil-HP Kit Tablet with Lovastatin can increase the risk of muscle problems.

How to manage the interaction:
Co-administration of Evoxil-HP Kit Tablet and Lovastatin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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AMOXYCILLIN-750MG+CLARITHROMYCIN-500MG+PANTOPRAZOLE-40MGFruit juices
Mild

Drug-Food Interactions

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AMOXYCILLIN-750MG+CLARITHROMYCIN-500MG+PANTOPRAZOLE-40MGFruit juices
Mild
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice with Evoxil-HP Kit Tablet may delay the gastrointestinal absorption of Evoxil-HP Kit Tablet. Avoid Grapefruit juice while being treated with Evoxil-HP Kit Tablet.

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Avoid tight-fitting clothes.
  • Avoid foods such as high-fat, spicy foods, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
  • Avoid sitting continuously, as it may trigger acidity. Take a 5-minute break every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTIULCERS

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Evoxil-HP Kit Tablet 1's. Alcohol intake leads to increased production of stomach acid.

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Pregnancy

Consult your doctor

Consult your doctor before taking Evoxil-HP Kit Tablet 1's if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Evoxil-HP Kit Tablet 1's. Your doctor will decide whether Evoxil-HP Kit Tablet 1's can be taken by breastfeeding mothers or not.

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Driving

Caution

Evoxil-HP Kit Tablet 1's causes dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Evoxil-HP Kit Tablet 1's if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Evoxil-HP Kit Tablet 1's if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Evoxil-HP Kit Tablet 1's should not be given to children as the safety and effectiveness were not established.

FAQs

Evoxil-HP Kit Tablet 1's is used in the treatment of peptic ulcer disease caused by infection with a common type of bacteria called Helicobacter pylori (H. pylori). It works by inhibiting the action of the gastric proton pump and preventing the growth of microorganisms.

Speak to your doctor if you do not feel better even after taking Evoxil-HP Kit Tablet 1's for 14 days. Do not take Evoxil-HP Kit Tablet 1's for longer durations unless prescribed by the doctor.

Evoxil-HP Kit Tablet 1's may cause dizziness. Drive only if you are alert, and do not operate machinery if you feel dizzy after taking Evoxil-HP Kit Tablet 1's.

Avoid or limit the consumption of alcohol while on Evoxil-HP Kit Tablet 1's as it may lead to increased dizziness. Alcohol intake may also lead to excess production of stomach acid, thereby increasing acidity and heartburn.

Diarrhoea might be a side-effect of Evoxil-HP Kit Tablet 1's. Drink enough fluids and eat fibre-rich food if you experience diarrhoea after taking Evoxil-HP Kit Tablet 1's. If you find blood in your stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Evoxil-HP Kit Tablet 1's contains pantoprazole, which may increase the risk of bone fracture in the hip, spine, or wrist. Recent clinical studies indicated that pantoprazole may affect the absorption of certain nutrients and minerals required for maintaining good bone health, leading to fractures. This mainly occurs in people taking higher doses of Evoxil-HP Kit Tablet 1's for longer durations. Inform your doctor before taking Evoxil-HP Kit Tablet 1's if you have osteoporosis or if you are already taking corticosteroids.

Dry mouth could be a side effect of Evoxil-HP Kit Tablet 1's. Limiting caffeine intake, avoiding smoking, drinking enough water, and chewing sugar-free gum or candy might help stimulate saliva production and thereby prevent dry mouth.

Inform your doctor if you don’t get better after finishing the full course of treatment. Also, let your doctor know if your symptoms are getting worse while using Evoxil-HP Kit Tablet 1's. Your doctor may need to reassess your condition, possibly perform additional tests, and prescribe a different treatment if necessary.

A peptic ulcer is a sore that develops on the lining of your stomach, lower esophagus, or small intestine. It's usually caused by an infection with Helicobacter pylori (H. pylori) bacteria or prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs).

Do not use Evoxil-HP Kit Tablet 1's if you have a known hypersensitivity to Evoxil-HP Kit Tablet 1's. Use Evoxil-HP Kit Tablet 1's with caution if you have liver disease, as the antibiotics in Evoxil-HP Kit Tablet 1's can affect liver function. Inform your doctor if you have or ever had gastrointestinal bleeding, diabetes, myasthenia gravis (neuromuscular disease), bone fractures, or hypomagnesemia (low levels of magnesium). Also, let your doctor know if you are breastfeeding, pregnant or planning pregnancy.

Take Evoxil-HP Kit Tablet 1's 30-60 minutes before food or as advised by your doctor. Swallow it as a whole with a glass of water. But try to take it at the same time each day for better efficacy. Do not crush or chew it.

No, do not stop using Evoxil-HP Kit Tablet 1's even if you feel better, as stopping Evoxil-HP Kit Tablet 1's early can leave the infection untreated, which could lead to side effects. Therefore, complete the full course of treatment as prescribed by your doctor.

Common side effects of Evoxil-HP Kit Tablet 1's include nausea, diarrhoea, vomiting, stomach pain, altered taste, and headache. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Leeford Healthcare Limited , Leo House, Shaheed Bhagat Singh Nagar, Dugri-Dhandra Road, Near Joseph School , Ludhiana-141116.
Other Info - EVO0088

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