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compositionComposition:GLIMEPIRIDE-2MG+METFORMIN-500MG
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Prescription Medicine
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Glimzox-M2 Tablet is used to treat type 2 diabetes. It helps manage blood glucose levels in patients with diabetes and prevents diabetes-related complications like kidney damage, eye problems, and nerve issues.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

GLIMEPIRIDE-2MG+METFORMIN-500MG

Manufacturer/Marketer :

Mblaze Pharmaceuticals

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Glimzox-M2 Tablet

Glimzox-M2 Tablet is a prescription oral tablet used to manage type 2 diabetes in adults. This medicine helps control blood sugar levels when diet and exercise alone are not enough. It is designed to keep your blood sugar within a healthy range to prevent long-term health complications.

For the best results, you must take Glimzox-M2 Tablet consistently every day as prescribed by your doctor. It is typically taken with meals, which helps reduce the chance of experiencing stomach upset. Combining this medicine with a balanced diet and regular physical activity is essential to achieve proper blood sugar control.

Some people may experience mild side effects, such as a temporary upset stomach or a metallic taste in the mouth. However, you should contact your doctor immediately if you experience signs of extremely low blood sugar, such as sweating, shaking, or confusion. Severe symptoms like persistent vomiting, deep rapid breathing, or unusual muscle pain also require urgent medical advice.

Before taking Glimzox-M2 Tablet , tell your doctor if you have kidney or liver issues, heart problems, or severe dehydration. Do not take this if you have type 1 diabetes, severe kidney failure, or diabetic ketoacidosis (a serious complication of diabetes). It is also unsafe for those with severe liver damage.

This medicine can interact with alcohol, which can dangerously increase the risk of low blood sugar or a rare but serious acid buildup in the blood. You should also tell your doctor about all other medicines you take, as some can affect how this tablet works. If you are pregnant, breastfeeding, or are an elderly individual, consult your doctor before starting this treatment to ensure it is safe for you.

Uses of Glimzox-M2 Tablet

Glimzox-M2 Tablet is used to treat Type 2 diabetes mellitus. The detailed uses of Glimzox-M2 Tablet are as follows:

  • Type 2 Diabetes Mellitus: Glimzox-M2 Tablet helps lower high blood sugar levels in adults whose diabetes cannot be controlled by diet, exercise, and single-medicine therapy alone.
  • Prevention of Diabetes Complications: By maintaining stable blood sugar levels, this medicine helps reduce the risk of serious long-term issues like kidney damage, nerve problems, blindness, and loss of limbs.

Key Benefits

Glimzox-M2 Tablet helps manage type 2 diabetes by combining two complementary blood sugar-lowering medicines in a single daily tablet. With regular use, it helps maintain stable blood sugar levels, improves daily well-being, and reduces the risk of long-term diabetes-related complications.

  • Provides Stable Blood Sugar Control: By lowering blood sugar through two different mechanisms, this medicine helps keep blood glucose levels within a healthy range, reducing symptoms such as excessive thirst, frequent urination, and energy fluctuations.
  • Improves Daily Well-Being: Maintaining stable blood sugar levels helps prevent sudden energy crashes, allowing you to stay more active and feel better throughout the day.
  • Protects Against Long-Term Complications: Consistent blood sugar control helps protect your blood vessels and vital organs, reducing the risk of complications such as kidney damage, nerve damage, vision problems, and cardiovascular disease.
Side effects of Glimzox-M2 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • Glimzox-M2 Tablet can be taken with meals or as prescribed by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Glimzox-M2 Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

How Glimzox-M2 Tablet Works

Glimzox-M2 Tablet works through a dual-action mechanism to control blood sugar levels. It contains two active ingredients that target different pathways in the body to manage type 2 diabetes effectively. The first active ingredient, glimepiride, which works by stimulating the pancreas to release more insulin, which is the natural hormone that helps your body process sugar. This helps lower the amount of glucose circulating in your bloodstream after meals. The second active ingredient, metformin, which works in two ways: it reduces the amount of sugar your liver produces and improves your body's sensitivity to insulin. This allows your muscles and tissues to absorb and use sugar from the blood more efficiently. Together, these two actions provide a highly effective way to keep your blood sugar within a target range.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Glimzox-M2 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

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Pregnancy

Unsafe

Glimzox-M2 Tablet is not recommended for pregnant women as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Glimzox-M2 Tablet as it may be excreted in breastmilk and cause adverse effects in the baby. Therefore, please consult a doctor before using Glimzox-M2 Tablet if you are breastfeeding.

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Driving

Caution

Glimzox-M2 Tablet may decrease alertness in some people. Therefore, drive only if you are alert after taking Glimzox-M2 Tablet .

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Liver

Caution

Take Glimzox-M2 Tablet with caution, especially if you have a history of liver diseases. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Glimzox-M2 Tablet with caution, especially if you have a history of kidney diseases. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Glimzox-M2 Tablet is not recommended for children as the safety and effectiveness were not established.

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Heart

Caution

Glimzox-M2 Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Glimzox-M2 Tablet .

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Geriatrics

Caution

Glimzox-M2 Tablet should be given with caution in elderly patients due to an increased risk of side effects. If you have any concerns about the usage of Glimzox-M2 Tablet in geriatrics, please consult your doctor.

What if I have taken an overdose of Glimzox-M2 Tablet

If you suspect an overdose, seek immediate medical attention or contact a poison control center right away. An overdose can cause severe low blood sugar or a dangerous buildup of acid in your blood, which requires urgent treatment in a hospital.

Diet & Lifestyle Advise

  • Monitor your carbohydrates: Focus on complex carbohydrates like whole grains, vegetables, and legumes, which release sugar slowly into your bloodstream, rather than simple sugars and refined flours.
  • Stay consistently active: Aim for at least 150 minutes of moderate physical activity, such as brisk walking, each week, as regular exercise helps your body use insulin more effectively.
  • Eat meals at regular times: Avoid skipping meals, especially when taking Glimzox-M2 Tablet , to prevent sudden drops in your blood sugar levels.
  • Keep a fast-acting sugar source nearby: Always carry a source of fast-acting sugar, such as fruit juice, hard candy, or glucose tablets, in case you experience symptoms of low blood sugar.
  • Stay hydrated: Drink plenty of water throughout the day to support your kidney function and help your body process the medication safely.
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Have a query?

How Soon It Starts Working

The time required for Glimzox-M2 Tablet to start to work: Glimzox-M2 Tablet ideally shows its action within few hours after administration. 

The time for which the effects of Glimzox-M2 Tablet last: The duration of action for Glimzox-M2 Tablet is clinically unknown.

What if you forget to take Glimzox-M2 Tablet

If you miss a dose, take it with your next meal if it is close to your scheduled time. However, if it is almost time for your next regular dose, skip the missed dose and resume your normal schedule. Do not take two doses at the same time to make up for a missed one, as this can cause your blood sugar to drop dangerously low.

Storage

•Store Glimzox-M2 Tablet at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from moisture and direct light.

Drug Warnings

  • Monitor your blood sugar regularly: Check your blood sugar levels as directed by your doctor to ensure the medicine is working safely and effectively.
  • Inform healthcare providers before surgery: Tell any surgeon, dentist, or doctor that you are taking Glimzox-M2 Tablet , as you may need to stop taking it temporarily before certain procedures or medical scans using contrast dyes.
  • Limit alcohol consumption: Avoid heavy drinking while taking this medicine, as alcohol significantly increases the risk of severe low blood sugar and lactic acid buildup.
  • Watch for signs of dehydration: Severe vomiting, diarrhoea, or not drinking enough fluids can increase the risk of serious side effects; contact your doctor if you cannot keep fluids down.
  • Check your feet daily: Diabetes can affect circulation and nerve health; inspect your feet regularly for any cuts, sores, or infections and report them to your doctor.

Drug-Drug Interactions

verifiedApollotooltip
  • Water pills (diuretics) and steroids: May raise your blood sugar levels, making Glimzox-M2 Tablet less effective.
  • Heart medicines (like beta-blockers): Can hide the warning signs of low blood sugar, such as a rapid heart rate.
  • Pain relievers (like NSAIDs) and certain blood pressure drugs: May increase the risk of kidney problems when combined with this medicine.
Glimepiride + MetforminGatifloxacin
Critical
Glimepiride + MetforminMetrizamide
Critical

Drug-Drug Interactions

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Glimepiride + MetforminGatifloxacin
Critical
How does the drug interact with Glimzox-M2 Tablet:
Taking Glimepiride with Gatifloxacin may cause both low blood glucose and high blood glucose have been reported.

How to manage the interaction:
Gatifloxacin is not recommended for patients with diabetes, however, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Do not discontinue the medications without consulting a doctor.
Glimepiride + MetforminMetrizamide
Critical
How does the drug interact with Glimzox-M2 Tablet:
Co-administration of Metformin and Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Metformin with Metrizamide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, nausea, vomiting, diarrhea, muscle cramps or pain, body weakness, extreme fatigue, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Glimepiride + MetforminIopromide
Critical
How does the drug interact with Glimzox-M2 Tablet:
Co-administration of Iopromide with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Iopromide with Metformin is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Glimepiride + MetforminIodixanol
Critical
How does the drug interact with Glimzox-M2 Tablet:
Co-administration of Iodixanol with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Metformin with Iodixanol is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Glimepiride + MetforminIodamide
Critical
How does the drug interact with Glimzox-M2 Tablet:
Co-administration of Metformin and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Metformin with Iodamide is generally avoided as it can result in an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Glimepiride + MetforminIomeprol
Critical
How does the drug interact with Glimzox-M2 Tablet:
Co-administration of Iomeprol with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Metformin with Iomeprol is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Glimepiride + MetforminIopamidol
Critical
How does the drug interact with Glimzox-M2 Tablet:
Co-administration of Iopamidol with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Metformin with Iopamidol is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Glimepiride + MetforminVoriconazole
Severe
How does the drug interact with Glimzox-M2 Tablet:
Co-administration of Glimepiride with Voriconazole may increase the blood levels and effects of Glimepiride.

How to manage the interaction:
Although there is a possible interaction, glimepiride can be taken with voriconazole if prescribed by the doctor. Consult a prescriber if you experience headache, dizziness, drowsiness, nervousness, confusion, tremors, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
Glimepiride + MetforminZonisamide
Severe
How does the drug interact with Glimzox-M2 Tablet:
The combined use of Metformin and Zonisamide may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Coadministration Metformin and Zonisamide can lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience any symptoms such as weakness, muscle pain, respiratory distress, fatigue, loss of appetite, slow or irregular heartbeat, breathing difficulty, or chills, consult a doctor immediately. Do not stop using any medication without a doctor's advice.
Glimepiride + MetforminEthanol
Severe
How does the drug interact with Glimzox-M2 Tablet:
Co-administration of Metformin with Ethanol may increase the risk of Lactic acidosis (excessive lactic acid production in blood).

How to manage the interaction:
Although there is a possible interaction between Metformin and Ethanol, you can take these medicines together if prescribed by a doctor. However, if you have symptoms such as weakness, muscle pain, increased drowsiness, dizziness, stomach pain or discomfort, slow or irregular heartbeat difficulty in breathing, or loss of appetite, contact a doctor immediately. Do not stop using any medications without a doctor’s advice.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Interacts dangerously by increasing the risk of extremely low blood sugar and a serious buildup of lactic acid in the blood.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Glimzox-M2 Tablet is indicated in the treatment of type 2 diabetes mellitus.
Glimzox-M2 Tablet works by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It helps the pancreas to produce insulin and helps the body use insulin efficiently.
In type 1 diabetes, the body does not produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completely. In type 2 diabetes, though islet cells are working, the body doesn't respond to insulin as the body becomes resistant to it.
You are not recommended to stop taking Glimzox-M2 Tablet on your own as discontinuing Glimzox-M2 Tablet suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Glimzox-M2 Tablet , please consult your doctor so that alternative medicine may be prescribed.
Include a diet rich in fruits, vegetables and whole grains like brown rice, whole wheat, oats, barley, and quinoa. Non-fat or low-fat dairy and proteins like chicken, lean meats, nuts, beans, tofu, lentils, eggs, fish, and turkey can also be included.
Store Glimzox-M2 Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Glimzox-M2 Tablet may cause lactic acidosis (builds up of lactic acid in the blood). Consult the doctor if you notice symptoms of lactic acidosis like abdominal pain, vomiting, muscle cramps, difficulty breathing, reduced body temperature and heartbeat, and severe tiredness.
Side effects of Glimzox-M2 Tablet are stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Long-term use of Glimzox-M2 Tablet may lead to vitamin B12 deficiency. Regular monitoring of vitamin B12 levels is recommended.
Glimzox-M2 Tablet should be swallowed as a whole with water; do not crush, break or chew it.
Regularly monitor blood glucose levels. Have your meals regularly and never miss a meal. Always carry a source of sugar and consume it if you experience low blood sugar. If you are due to undergo any tests or surgery, inform the doctor that you are taking Glimzox-M2 Tablet . Avoid drinking alcohol.
Other medicines should be taken with Glimzox-M2 Tablet only if prescribed by the doctor. To prevent any interactions it is advised to consult the doctor before taking other medicines during treatment with Glimzox-M2 Tablet .
It is highly recommended to avoid or strictly limit alcohol while taking Glimzox-M2 Tablet . Alcohol can cause your blood sugar to drop dangerously low and increase the risk of a rare but serious condition called lactic acidosis, which is an acid buildup in your blood. Talk to your doctor about safe alcohol limits for you.
If you experience signs of low blood sugar, such as shaking, sweating, or dizziness, immediately consume 15 to 20 grams of fast-acting sugar (like half a cup of fruit juice or 3 to 4 glucose tablets). Check your blood sugar again after 15 minutes. If symptoms persist or if you feel confused, seek immediate medical help. Talk to your doctor about how to manage these episodes.
Some patients may experience mild weight loss or a stable weight while taking this medication, primarily due to how one of the active ingredients affects insulin use and appetite. However, Glimzox-M2 Tablet is not a weight-loss drug and should only be used to manage blood sugar. Talk to your doctor for advice on managing your weight.
Glimzox-M2 Tablet is generally not recommended during pregnancy or breastfeeding, as alternative treatments are usually preferred to manage blood sugar during these times. If you are planning a pregnancy or become pregnant while taking this medicine, contact your healthcare provider immediately. Talk to your doctor to discuss safer alternatives.
Glimzox-M2 Tablet does not typically cause kidney damage, but your kidneys are responsible for clearing this medicine from your body. If your kidney function declines, the medicine can build up and cause serious side effects. Your doctor will perform routine blood tests to check your kidney health. Talk to your doctor if you have concerns about your kidneys.
You must temporarily stop taking Glimzox-M2 Tablet before or at the time of any imaging test that uses iodinated contrast dye, as the dye can temporarily affect your kidney function and increase the risk of a serious blood acid buildup. You can usually restart the medicine 48 hours after the procedure once your kidney function is checked. Talk to your doctor for specific instructions.

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Country of origin

INDIA

Manufacturer/Marketer address

Murali Nagar, Visakhapatnam-530012, Andhra Pradesh, India
Other Info - GLI0996
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