HAPPI 20MG I.V INJECTION

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Written By Santoshini Reddy G , M Pharmacy

Reviewed By Veda Maddala , M Pharmacy

HAPPI 20MG I.V INJECTION belongs to the class of proton pump inhibitors. It is used in the treatment of Gastro-oesophageal reflux disease (GERD), duodenal/gastric ulcers, and Zollinger-Ellison syndrome. It contains rabeprazole, which help decrease the amount of acid in the stomach. Some of the common side effects include headache, diarrhoea, constipation, abdominal pain, flatulence, vomiting, nausea, etc.

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About HAPPI 20MG I.V INJECTION

HAPPI 20MG I.V INJECTION is used to treat gastric/duodenal ulcers, gastro-oesophageal reflux disease (GERD), heartburn, prevention of acid-aspiration, stress-induced mucosal injury, and Zollinger-Ellison syndrome.

HAPPI 20MG I.V INJECTION contains 'Rabeprazole' that works by blocking the action of the enzyme known as gastric proton pump, which is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

In some cases, you may experience certain common side effects, such as pain at the site of injection, diarrhoea, dizziness, dry mouth, headache, and abdominal pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

On long-term treatment, HAPPI 20MG I.V INJECTION may cause low magnesium levels and vitamin B12 levels and increase the risk of bone fractures. Consult your doctor if you are pregnant or breastfeeding. HAPPI 20MG I.V INJECTION may cause dizziness, so drive only if you are alert. HAPPI 20MG I.V INJECTION is not recommended for children as safety has not been established. Avoid consuming alcohol along with HAPPI 20MG I.V INJECTION as it could lead to increased drowsiness and can elevate the production of stomach acid.

Uses of HAPPI 20MG I.V INJECTION

HAPPI 20MG I.V INJECTION is used in the treatment of Gastro-oesophageal reflux disease (GERD), Duodenal/Gastric ulcers, and Zollinger-Ellison syndrome. The detailed uses of HAPPI 20MG I.V INJECTION are as follows:<br/>• Treatment of Gastro-oesophageal Reflux Disease (GERD): HAPPI 20MG I.V INJECTION helps to manage symptoms of GERD, such as heartburn and acid reflux, by reducing stomach acid production.<br/>• Relief from Duodenal/Gastric Ulcers: HAPPI 20MG I.V INJECTION helps to treat duodenal and gastric ulcers by reducing stomach acid, allowing the ulcers to heal.<br/>• Management of Zollinger-Ellison Syndrome: HAPPI 20MG I.V INJECTION manages excessive acid production in the stomach, helping to alleviate symptoms and prevent complications associated with the condition.<br/>

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Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• HAPPI 20MG I.V INJECTION will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

HAPPI 20MG I.V INJECTION belongs to a group of antiulcer medicines called proton pump inhibitors. HAPPI 20MG I.V INJECTION is used to treat gastric ulcers, duodenal ulcers, gastro-oesophageal reflux disease (GERD), heartburn, prevention of acid-aspiration, stress-induced mucosal injury, and Zollinger-Ellison syndrome. HAPPI 20MG I.V INJECTION works by blocking the action of the enzyme known as gastric proton pump, which is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

How HAPPI 20MG I.V INJECTION Works

HAPPI 20MG I.V INJECTION contains 'Rabeprazole' that works by blocking the action of the enzyme known as gastric proton pump, which is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

Storage

• Store in a cool and dry place away from sunlight.• Keep HAPPI 20MG I.V INJECTION out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ÂºC to 25ÂºC or below 30ÂºC.

Side effects of Happi 20mg I.v Injection

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Gas Or Fart

Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:

Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.

Pain

Apply a hot/cold pack to the affected area.
Doing gentle exercises can help cope with pain by stretching muscles.
Get enough sleep. It helps enhance mood and lower pain sensitivity.
Avoid alcohol, smoking and tobacco as they can increase pain.
Follow a well-balanced meal.
Meditation and massages may also help with pain.

Sore Throat

Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
Gargle with warm salt water.
Suck on lozenges to increase the production of saliva and soothe your throat.
Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of HAPPI 20MG I.V INJECTION

A health care professional administers HAPPI 20MG I.V INJECTION in a hospital. Hence, the chances of overdose are less. Overdose of HAPPI 20MG I.V INJECTION may cause heartburn, stomach ulcer from aspirin/ibuprofen-like drugs prevention, excessive production of stomach acid, gastroesophageal reflux disease, inflammation of the stomach lining, bleeding from the stomach, and oesophagus or duodenum. Your doctor will take the necessary measures if an overdose is suspected.

Drug Warnings

Do not take HAPPI 20MG I.V INJECTION if you are allergic to any of its contents. Inform your doctor if you have a stomach tumour, liver disease, or if you are due to have Chromogranin A blood test. On long-term treatment, HAPPI 20MG I.V INJECTION may cause low magnesium levels, vitamin B12 levels, and increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition. Consult your doctor before starting HAPPI 20MG I.V INJECTION if you are pregnant or breastfeeding. HAPPI 20MG I.V INJECTION may cause dizziness, so drive only if you are alert. HAPPI 20MG I.V INJECTION is not recommended for children as safety has not been established. Avoid consuming alcohol along with HAPPI 20MG I.V INJECTION as it could lead to increased drowsiness and can elevate the production of stomach acid. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions

RabeprazoleErlotinib

Critical

RabeprazoleRilpivirine

Critical

Drug-Drug Interactions

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RabeprazoleErlotinib

Critical

How does the drug interact with Happi 20mg I.v Injection:
When used in combination with erlotinib, Happi 20mg I.v Injection may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking Happi 20mg I.v Injection with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.

RabeprazoleRilpivirine

Critical

How does the drug interact with Happi 20mg I.v Injection:
Co-administration of Happi 20mg I.v Injection can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Happi 20mg I.v Injection with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.

RabeprazolePhenytoin

Severe

How does the drug interact with Happi 20mg I.v Injection:
When Phenytoin and Happi 20mg I.v Injection are taken in combination, Phenytoin will reduce the concentration or impact of Happi 20mg I.v Injection.

How to manage the interaction:
Although taking Phenytoin and Happi 20mg I.v Injection together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

RabeprazolePazopanib

Severe

How does the drug interact with Happi 20mg I.v Injection:
Taking Happi 20mg I.v Injection together with Pazopanib can result in a decreased effectiveness of Pazopanib in treating the disease.

How to manage the interaction:
Although taking Happi 20mg I.v Injection and Pazopanib together can result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.

RabeprazoleAcalabrutinib

Severe

How does the drug interact with Happi 20mg I.v Injection:
Taking Happi 20mg I.v Injection together with Acalabrutinib results in a decreased effectiveness of Acalabrutinib.

How to manage the interaction:
Although taking Happi 20mg I.v Injection and Acalabrutinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

RabeprazoleClopidogrel

Severe

How does the drug interact with Happi 20mg I.v Injection:
Taking Clopidogrel with Happi 20mg I.v Injection can reduce the effectiveness of Clopidogrel.

How to manage the interaction:
Taking Clopidogrel and Happi 20mg I.v Injection together possibly has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.

RabeprazoleAtazanavir

Severe

How does the drug interact with Happi 20mg I.v Injection:
Co-administration of Atazanavir's blood levels and absorption can both be affected by Happi 20mg I.v Injection, which decreases the atazanavir's ability to treat HIV.

How to manage the interaction:
Although taking Happi 20mg I.v Injection and atazanavir together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

RabeprazoleIdelalisib

Severe

How does the drug interact with Happi 20mg I.v Injection:
When Happi 20mg I.v Injection and Idelalisib are taken in combination, Idelalisib may increase the level or impact of Happi 20mg I.v Injection.

How to manage the interaction:
Although taking Happi 20mg I.v Injection and Idelalisib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

RabeprazoleDasatinib

Severe

How does the drug interact with Happi 20mg I.v Injection:
Taking Happi 20mg I.v Injection together with Dasatinib results in decreased levels of Dasatinib and its effectiveness.

How to manage the interaction:
Although taking Happi 20mg I.v Injection and Dasatinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

RabeprazoleGefitinib

Severe

How does the drug interact with Happi 20mg I.v Injection:
Taking Happi 20mg I.v Injection together with Gefitinib results in decreased levels of gefitinib in your blood. This can result in a decreased effectiveness of gefitinib in treating the disease.

How to manage the interaction:
Although taking Happi 20mg I.v Injection and Gefitinib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. To lessen the effects of the interaction, it is advised that you take gefitinib 12 hours before or 12 hours after Happi 20mg I.v Injection. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Eat smaller meals more often.
Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
Maintain a healthy weight by regular exercising.
Avoid lying down after eating to prevent acid reflux.
Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
Practise relaxation techniques and avoid stress by doing yoga or meditation.
Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

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Alcohol

Unsafe

Avoid consumption of alcohol while taking HAPPI 20MG I.V INJECTION. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

Pregnancy

Caution

Please consult your doctor if you are pregnant. Your doctor will weigh the benefits and any potential risks before prescribing HAPPI 20MG I.V INJECTION.

Breast Feeding

Caution

Please consult your doctor if you are breastfeeding. Your doctor will decide if HAPPI 20MG I.V INJECTION can be taken by breastfeeding mothers or not.

Driving

Caution

HAPPI 20MG I.V INJECTION may cause dizziness. Do not drive or operate machinery unless you are alert.

Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this.

Children

Unsafe

HAPPI 20MG I.V INJECTION is not recommended for children as the safety and effectiveness were not established.

FAQs

What is the use of HAPPI 20MG I.V INJECTION?

HAPPI 20MG I.V INJECTION is used to treat gastric/duodenal ulcers, gastro-oesophageal reflux disease (GERD), heartburn, prevention of acid-aspiration, stress-induced mucosal injury, and Zollinger-Ellison syndrome.

How does HAPPI 20MG I.V INJECTION work?

HAPPI 20MG I.V INJECTION works by blocking the action of the enzyme known as gastric proton pump that is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

Does HAPPI 20MG I.V INJECTION cause diarrhoea?

Diarrhoea might be a side-effect of HAPPI 20MG I.V INJECTION. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Prolonged intake of HAPPI 20MG I.V INJECTION is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor.

Does HAPPI 20MG I.V INJECTION cause dry mouth?

Dry mouth could be a side-effect of HAPPI 20MG I.V INJECTION. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Does HAPPI 20MG I.V INJECTION increase the risk of bone fractures?

On long-term treatment, HAPPI 20MG I.V INJECTION might increase the risk of fractures of the hip, spine, and wrist. Inform your doctor if you have osteoporosis or if you are taking corticosteroids.

Does HAPPI 20MG I.V INJECTION increase the risk of bleeding?

HAPPI 20MG I.V INJECTION may increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice any signs of increased bleeding or bruising.

Country of origin

INDIA

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads, Ahmedabad – 380015, Gujarat, India.

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