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  3. Inlyta 1mg Tablet 28's

Inlyta 1mg Tablet 28's, Pack of 1 TABLET
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Composition :

AXITINIB-1MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Inlyta 1mg Tablet

Inlyta 1mg Tablet is an anti-cancer medicine used in the treatment of renal cell carcinoma. Renal cell carcinoma, also known as kidney cancer, is a disease in which the cancer or malignant cells grow uncontrollably in the kidney and form a tumour.

Inlyta 1mg Tablet contains Axitinib as an active ingredient, which belongs to the class of medicines known as kinase inhibitors. It works by inhibiting the action of an enzyme (tyrosine kinase) and thus stops the abnormal growth of cancer cells.

Inlyta 1mg Tablet may cause certain side effects such as diarrhea, rash, tiredness, decreased appetite, nausea, vomiting, increased blood pressure, muscle cramps, chest pain, weakness, dizziness, hoarseness, and constipation. Inform your doctor if any of these side effects bother you. Inlyta 1mg Tablet should be taken as advised by your doctor.

Avoid taking Inlyta 1mg Tablet if you are allergic to it or any other components of it. Before taking Inlyta 1mg Tablet , inform your doctor if you have/had liver or kidney disease, gastrointestinal disorders, heart problems, thyroid disorders, or blood disorders. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy and breastfeeding.

Uses of Inlyta 1mg Tablet

Inlyta 1mg Tablet is used in the treatment of Renal Cell Carcinoma. The detailed use of Inlyta 1mg Tablet is as follows:<br/>• Advanced Renal Cell Carcinoma (RCC): Inlyta 1mg Tablet is commonly prescribed for RCC, especially in patients who have not responded to previous treatments.<br/>

Directions for Use

• Inlyta 1mg Tablet can be taken with or without food as prescribed by your doctor.• It is recommended to take twice daily; however, follow your doctor's advice regarding the dosage and duration.• Swallow the medicine as a whole with a glass of water.• Do not break, chew or crush Inlyta 1mg Tablet .

Medicinal Benefits

Inlyta 1mg Tablet contains Axitinib, which is used in treating advanced renal cell carcinoma after failure of prior systemic therapy. It works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. It also decreases the blood supply to cancer tumors to slow down the growth of the tumor.  In this way, Inlyta 1mg Tablet stops the body's production, spread and growth of cancerous cells.

How Inlyta 1mg Tablet Works

Inlyta 1mg Tablet contains Axitinib as an active ingredient, which belongs to the class of medicines known as kinase inhibitors. It works by inhibiting the action of an enzyme (tyrosine kinase) and thus stops the abnormal growth of cancer cells.

Storage

Store in a cool and dry place away from sunlight
Side effects of Inlyta 1mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
  • Prefer foods high in fiber to help feel full for a long time.
  • If you have decreased appetite, eat only when you are hungry.
  • Eat several small meals or snacks all day.
  • Try to take only small sips of fluids while eating.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Inlyta 1mg Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Inlyta 1mg Tablet may include dizziness, coughing up blood, and seizures. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

To treat your condition effectually, continue taking Inlyta 1mg Tablet for the period that your doctor has prescribed. Avoid taking Inlyta 1mg Tablet if you are allergic to it or any other components present in it. Caution should be exercised if you have/had liver or kidney disease, any planned surgery, heart disease, stroke, blood or bleeding disorders, or gastrointestinal disorders. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment as this medicine is known to cause embryo-fetal toxicity. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. Avoid driving and operating machines, as this medicine may cause visual disturbances. This medicine is not recommended for use in children below 18 years of age as the safety and efficacy are not established. Inlyta 1mg Tablet may cause hypertension, arterial and venous thrombotic events, hemorrhagic events, hypothyroidism, gastrointestinal perforation and fistula, Reversible Posterior Leukoencephalopathy Syndrome (RPLS), elevated liver enzymes in some patients. Hence, inform your doctor about your complete medication and medical history before taking Inlyta 1mg Tablet .

Drug-Drug Interactions

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AxitinibEfavirenz
Severe
AxitinibIndinavir
Severe

Drug-Drug Interactions

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AxitinibEfavirenz
Severe
How does the drug interact with Inlyta 1mg Tablet:
Efavirenz may decrease the blood levels of Inlyta 1mg Tablet, which may make Inlyta 1mg Tablet less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Inlyta 1mg Tablet and Efavirenz, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
AxitinibIndinavir
Severe
How does the drug interact with Inlyta 1mg Tablet:
When Inlyta 1mg Tablet is taken with Indinavir, the body's ability to break down Inlyta 1mg Tablet may be reduced.

How to manage the interaction:
Although taking Inlyta 1mg Tablet and Indinavir together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience Chest pain or pressure, pain in the arms, back, neck, or jaw, swelling, shortness of breath, numbness or weakness on one side of the body, headache, vision changes, seizures, unusual bleeding or bruising, red or black stools, coughing up or vomiting blood or blood clots, and extreme stomach or abdominal pain, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
AxitinibBosentan
Severe
How does the drug interact with Inlyta 1mg Tablet:
Taking Inlyta 1mg Tablet with bosentan may significantly reduce the blood levels of Inlyta 1mg Tablet, making the medication less effective in treating the condition.

How to manage the interaction:
Although using Bosentan and Inlyta 1mg Tablet together can result in an interaction, they can be taken together if advised by a doctor. Do not stop taking any medications without consulting a doctor.
AxitinibCobicistat
Severe
How does the drug interact with Inlyta 1mg Tablet:
When Inlyta 1mg Tablet is taken with Cobicistat, the body's ability to break down Inlyta 1mg Tablet is reduced.

How to manage the interaction:
There may be a possibility of interaction between Cobicistat and Inlyta 1mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience Chest pain or pressure, pain in the arms, back, neck, or jaw, swelling, shortness of breath, numbness or weakness on one side of the body, headache, vision changes, seizures, unusual bleeding or bruising, red or black stools, coughing up or vomiting blood or blood clots, and extreme stomach or abdominal pain, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
AxitinibPhenobarbital
Severe
How does the drug interact with Inlyta 1mg Tablet:
Phenobarbital can considerably lower Inlyta 1mg Tablet levels in the blood, making the medicine less effective in treating the illness.

How to manage the interaction:
Although taking phenobarbital with Inlyta 1mg Tablet can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
AxitinibRifapentine
Severe
How does the drug interact with Inlyta 1mg Tablet:
Rifapentine may decrease the blood levels of Inlyta 1mg Tablet, which may make Inlyta 1mg Tablet less effective in treating the condition.

How to manage the interaction:
There may be a possibility of interaction between Inlyta 1mg Tablet and Rifapentine, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
AxitinibRifabutin
Severe
How does the drug interact with Inlyta 1mg Tablet:
Coadministration of Rifabutin may decrease the blood levels of Inlyta 1mg Tablet.

How to manage the interaction:
Although taking Inlyta 1mg Tablet and Rifabutin together can cause an interaction, it can be taken if a doctor has suggested it. If you experience any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.
AxitinibTroleandomycin
Severe
How does the drug interact with Inlyta 1mg Tablet:
Co-administration of Inlyta 1mg Tablet with troleandomycin may cause Inlyta 1mg Tablet blood levels to rise significantly, leading to an increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Inlyta 1mg Tablet and Troleandomycin, you can take these medicines together if prescribed by a doctor. However, if you experience high blood pressure, diarrhea, nausea, vomiting, constipation, decreased appetite, weight loss, rash, itching or peeling of skin on the hands and feet, chest pain or pressure, pain in the arms, back, neck or jaw, swelling, shortness of breath, numbness or weakness on one side of the body, headache, vision changes, seizures, unusual bleeding or bruising, red or black stools, coughing up or vomiting blood or blood clots, and severe stomach or abdominal pain, consult a doctor. Do not stop using any medications without a doctor’s advice.
AxitinibTeriflunomide
Severe
How does the drug interact with Inlyta 1mg Tablet:
When Inlyta 1mg Tablet is taken with Teriflunomide, the risk of liver problems increases.

How to manage the interaction:
Taking Inlyta 1mg Tablet with Teriflunomide together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
AxitinibBoceprevir
Severe
How does the drug interact with Inlyta 1mg Tablet:
When Inlyta 1mg Tablet and boceprevir are taken together it may considerably raise Inlyta 1mg Tablet levels in the blood. This may eventually result in increased side effects.

How to manage the interaction:
Co-administration of Inlyta 1mg Tablet with Boceprevir can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain or pressure; pain in the arms, back, neck, or jaw; swelling; shortness of breath; numbness or weakness on one side of the body; headache; vision changes; seizures, unusual bleeding or bruising; red or black stools; coughing up or vomiting blood or blood clots; and severe stomach or abdominal pain, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AXITINIB-1MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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AXITINIB-1MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit or grapefruit juice might raise the medication's levels in the blood leading to side effects such as high blood pressure, diarrhea, nausea, vomiting, constipation, decreased appetite, weight loss, and rash, itching or peeling of skin on the hands and feet. Avoid consuming grapefruit or grapefruit juice during treatment with Inlyta 1mg Tablet.

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles, reduces fatigue, helps in weight loss, and gives strength. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, etc.
  • Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains, nuts, and seeds.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Inlyta 1mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Limit alcohol consumption while taking Inlyta 1mg Tablet .

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Pregnancy

Unsafe

Inlyta 1mg Tablet is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Inlyta 1mg Tablet . You should not become pregnant while you are taking Inlyta 1mg Tablet . Using effective birth control methods while on treatment with Inlyta 1mg Tablet is suggested.

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Breast Feeding

Caution

It is not known whether Inlyta 1mg Tablet passes into breastmilk. Hence, if you are breastfeeding, inform your doctor before taking Inlyta 1mg Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

bannner image

Driving

Unsafe

Inlyta 1mg Tablet may cause dizziness and visual disturbances in some patients. Hence, do not drive, operate machinery, or engage in any activity that needs clear vision until you are confident that you can do so safely while you are on treatment with Inlyta 1mg Tablet .

bannner image

Liver

Caution

If you have a pre-existing or a history of liver problems, tell your doctor before taking this medicine. Inlyta 1mg Tablet is known to cause elevated liver enzymes, which may be fatal. Hence, this medicine should be taken cautiously in patients with moderate liver impairment. Your doctor may suggest tests to monitor your liver function while on treatment with this medicine.

bannner image

Kidney

Caution

If you have a pre-existing or a history of kidney diseases, inform your doctor before taking Inlyta 1mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Children

Unsafe

Inlyta 1mg Tablet is not recommended for use in children below 18 years of age as the safety and efficacy is not established.

Have a query?

FAQs

Inlyta 1mg Tablet is used to treat Renal Cell Carcinoma.

Inlyta 1mg Tablet contains Axitinib, which works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells.

Inlyta 1mg Tablet is safe to be taken by a diabetic person. However, take Inlyta 1mg Tablet only after consulting with a doctor, as they may adjust the dosing according to your condition.

Inlyta 1mg Tablet may cause thyroid dysfunction, leading to decreased thyroid hormone levels. This effect causes hypothyroidism. So, notify your doctor if you feel extremely tired, colder than others, sudden weight gain/ weight loss, hair loss, or change in voice while using this medicine.

The possible signs and symptoms of kidney cancer are haematuria (blood in urine), low back pain on one side, fever, fatigue, weight loss, loss of appetite, anaemia (low blood count), and a lump on the side or lower back.

Inlyta 1mg Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.

Seek medical attention immediately if you have swelling in your lower legs, fast heartbeats, or trouble breathing as it may be a sign of a heart problem.

Your doctor may suggest blood tests, and liver & kidney function tests before starting Inlyta 1mg Tablet . If you are female, you will have to take a pregnancy test before starting treatment.

People who are allergic to any of the components in Inlyta 1mg Tablet should not take this medicine. It is also not recommended during pregnancy and breastfeeding.

Yes, Inlyta 1mg Tablet might decrease fertility in men and women. Talk to the doctor if you have any concerns regarding fertility during treatment with Inlyta 1mg Tablet .

Fatigue could be a side effect of Inlyta 1mg Tablet . To cope with fatigue rest properly, eat healthy food, limit alcohol/caffeine, and manage stress. However, consult the doctor if you have excessive tiredness as it could be a sign of heart failure.

Consult your doctor if you get tired more easily, generally feel colder than other people, or your voice deepens whilst taking this medicine as these could be signs of the thyroid problem. The doctor will recommend thyroid function tests before and during treatment with Inlyta 1mg Tablet .

Posterior Reversible Leukoencephalopathy Syndrome is a neurological condition characterised by headache, seizures (fits), confusion, and changes in vision with or without high blood pressure. Consult the doctor immediately if you notice these symptoms.

Swelling of the abdomen, legs or ankles, protruding neck veins, excessive tiredness, and shortness of breath could be an indication of heart failure. Consult the doctor if you experience these symptoms.

Store Inlyta 1mg Tablet at room temperature, in a dry place. Keep out of sight and reach of children.

Inlyta 1mg Tablet may cause side effects such as diarrhoea, rash, tiredness, decreased appetite, nausea, vomiting, increased blood pressure, muscle cramps, chest pain, weakness, dizziness, hoarseness, and constipation. Inform your doctor if any of these side effects bother you.

Country of origin

INDIA

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051
Other Info - INL0074

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:05 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202324lbl.pdf
  2. https://www.drugs.com/mtm/axitinib.html
  3. https://medlineplus.gov/druginfo/meds/a612017.html
  4. https://reference.medscape.com/drug/inlyta-axitinib-999715
  5. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/axitinib

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