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compositionComposition:ISOTRETINOIN-10MG
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Prescription Medicine
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ISOTRETINOIN-10MG

Manufacturer/Marketer :

Roussel Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Isoros 10 mg Tablet

Isoros 10 mg Tablet is a prescription medication primarily used to treat severe, painful, and deep nodular acne. When other treatments like topical creams or oral antibiotics fail to clear your skin, doctors prescribe this medication to help control severe breakouts and prevent long-term damage. It works by targeting the root causes of severe acne to give you clearer skin.

During the first few weeks of treatment, some people may notice a temporary increase in acne breakouts, redness, or skin irritation. This initial flare happens as the medicine begins changing oil production and skin cell activity. It usually improves with continued treatment, but inform your doctor if the worsening is severe, painful, or difficult to manage.

To achieve the best results, you must take this medication consistently every day, typically once or twice daily as directed by your doctor. It is highly recommended to take this capsule with a meal containing healthy fats, as food significantly increases how well your body absorbs the medicine. Alongside your treatment, adopting a gentle skincare routine, staying hydrated, and avoiding harsh facial scrubs can help support your skin's healing process.

While this medication is highly effective, it is common to experience side effects such as dry skin, chapped lips, and dry eyes. However, you must contact your doctor immediately if you experience more serious issues, such as severe stomach pain, changes in your vision, or sudden changes in your mood or mental health.

Talk to your doctor before starting this treatment if you have a history of liver problems, high blood lipids, depression, or diabetes. Do not take this medicine if you are pregnant, planning to become pregnant, or breastfeeding, as it carries an extremely high risk of causing severe, life-threatening birth defects.

This medication can interact with other substances; for instance, you should avoid taking vitamin A supplements, certain tetracycline antibiotics, or consuming alcohol while on this treatment. If you are part of a specific group, such as the elderly or those with underlying metabolic conditions, consult your healthcare provider to discuss safe usage.

Uses of Isoros 10 mg Tablet

Your doctor may prescribe this medicine to treat several conditions, including:

  • Severe nodular acne:  Isoros 10 mg Tablet helps clear deep, painful lumps and cysts under the skin when other standard treatments, including oral antibiotics, do not work.
  • Acne scarring prevention: By rapidly clearing severe acne lesions, this medicine helps prevent permanent physical scarring and long-term skin texture damage.
  • Other uses: In some cases, doctors may prescribe Isoros 10 mg Tablet for conditions other than severe acne, such as certain difficult-to-treat skin disorders including rosacea or hidradenitis suppurativa. These uses may be based on specialist judgment and are not the primary approved use of the medicine.
     

Key Benefits

Isoros 10 mg Tablet provides powerful acne treatment by targeting severe breakouts and addressing the underlying causes of acne formation. By reducing oil production and preventing new lesions, this medicine offers several key health benefits:

  • Long-Lasting Control of Severe Acne: Isoros 10 mg Tablet helps clear persistent, severe acne and may provide lasting improvement after completing a prescribed treatment course, reducing the need for continuous acne medications.
  • Relief from Painful Acne Lesions: By reducing deep, inflamed cysts and nodules, Isoros 10 mg Tablet helps decrease skin tenderness, soreness, and discomfort caused by severe breakouts.
  • Prevention of New Acne Formation: Isoros 10 mg Tablet helps interrupt the cycle of recurring breakouts, allowing the skin barrier to heal and reducing the likelihood of new severe acne lesions developing over time.
     
Side effects of Isoros 10 mg Tablet
Managing Medication-Triggered Cheilitis (Inflammation of the lips): A Step-by-Step Guide:
  • Consult your doctor if you experience lip inflammation, redness, or irritation after taking medication.
  • Your doctor will assess your condition, investigate possible causes, and design a treatment plan.
  • To soothe and moisturize the lips, use topical creams or ointments like petroleum jelly or lip balm.
  • Practice good lip care by keeping your lips clean, avoiding irritants, and staying hydrated.
  • If your condition worsens or persists, speak with your doctor about further therapy.
  • Exercise and a healthy diet can help manage high cholesterol, but consult your doctor about medication if lifestyle changes are not enough.
  • Avoid foods high in cholesterol, saturated fat, and trans fats, such as egg yolks, cheese, fried foods, pastries, ice cream, and red meat.
  • Increase your intake of vegetables, fruits, oats, whole grains, lentils, and beans to boost fibre consumption.
  • Include foods rich in monounsaturated fats, like nuts, avocados, olive oil, and oily fish.
  • Exercise regularly for 30 minutes and maintain a healthy weight.
  • Quit smoking and limit excessive alcohol consumption, as both can negatively impact your cholesterol levels.
  • If you notice increased red blood cell sedimentation rate (ESR) after starting a medication, consult your doctor so that they may advise possible medication adjustments.
  • Regular blood tests are advised to monitor your ESR levels to assess the effectiveness of any treatment plan.
  • Eat a well-balanced diet rich in nutrients and antioxidants to reduce inflammation.
  • Drink lots of water to maintain proper blood viscosity.
  • Do regular physical activity as it helps to manage chronic conditions that may contribute to high ESR.
  • If you a smoker, quit smoking as it can negatively impact ESR levels.
  • Apply a gentle lip balm with ingredients such as castor seed oil or shea butter.
  • Ensure you are hydrated by drinking plenty of water; this helps heal your lips.
  • Avoid licking your lips or picking at them.
  • Use a humidifier at home, particularly at night, to maintain moisture in the air.
  • Protect your lips from sun exposure by using SPF lip balm and avoid using any irritating components.
  • Stay away from metal objects that could irritate your lips.
  • Consume a vitamin-rich diet to enhance the health of your skin overall.

Directions for Use

Take  Isoros 10 mg Tablet exactly as prescribed by your healthcare provider. Follow these simple steps for safe administration:

  • Swallow the capsule whole with a full glass of water. Do not chew, crush, or suck on the capsule.
  • Take this medicine with a high-fat meal or snack, as food significantly increases how well your body absorbs it.
  • Take your doses at the same time(s) each day to maintain a steady level of the medicine in your body.

Always follow your doctor's exact instructions regarding your daily dose and how long to continue the treatment. Do not adjust your dose or stop taking this medicine without consulting your healthcare provider first.
 

How Isoros 10 mg Tablet Works

Isoros 10 mg Tablet contains isotretinoin. It targets all four major causes of severe acne. First, it significantly shrinks the oil-producing glands (sebaceous glands) in your skin, reducing the amount of natural oil they produce. Less oil means fewer clogged pores where acne can start. Second, it slows down the rapid growth of skin cells inside your pores, preventing blockages that lead to blackheads and pimples. Third, by reducing the skin's oil content, it naturally starves and decreases the population of acne-causing bacteria. Finally, it calms the severe redness, swelling, and deep inflammation associated with painful nodular lesions.
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Alcohol

Unsafe

Avoid consumption of alcohol with Isoros 10 mg Tablet as it may increase the risk of liver damage and cause a rise in cholesterol levels.

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Pregnancy

Unsafe

Isoros 10 mg Tablet is a Category X pregnancy drug and is considered unsafe for pregnant women as it may cause severe birth defects. Please consult a doctor if you are pregnant or planning to become pregnant.

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Breast Feeding

Unsafe

Isoros 10 mg Tablet may be excreted in breast milk and cause adverse effects in the baby. Please consult a doctor before using Isoros 10 mg Tablet while breastfeeding.

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Driving

Caution

Isoros 10 mg Tablet may reduce night vision in some patients. Therefore, drive only if you are alert after taking Isoros 10 mg Tablet .

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Liver

Unsafe

Isoros 10 mg Tablet is usually not recommended for patients with impaired liver function. If you have any concerns regarding the use of Isoros 10 mg Tablet in patients with liver problems, please consult a doctor.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Isoros 10 mg Tablet in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Isoros 10 mg Tablet is not recommended for children below 12 years of age.

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Heart

Consult your doctor

If you have any concerns regarding the use of Isoros 10 mg Tablet in patients with heart problems, please consult a doctor.

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Geriatrics

Consult your doctor

Limited information is available. Please consult your doctor.

What if I have taken an overdose of Isoros 10 mg Tablet

Do not take more than the prescribed dose of Isoros 10 mg Tablet as it may cause an overdose. The symptoms of overdose include vomiting, dizziness, headache, stomach pain, loss of balance or coordination, warmth or tingling in your face and swollen or cracked lips. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Avoid taking any vitamin A supplements or multivitamins containing Vitamin A, as this can cause a dangerous buildup of the vitamin in your body.
  • Protect your skin from the sun. Apply a broad-spectrum sunscreen with SPF 30 or higher daily, and wear protective clothing, as your skin will burn much faster.
  • Moisturise your skin, lips, and eyes daily. Use a thick, fragrance-free moisturiser, lip balm, and lubricating eye drops to manage dryness.
  • Avoid cosmetic skin treatments like waxing, chemical peels, or dermabrasion while taking this medicine and for at least six months after stopping, as your skin is highly fragile and may scar.
  • Stay well-hydrated by drinking plenty of water throughout the day to help manage dry skin and eyes.
     

Have a query?

How Soon It Starts Working

The time required for Isoros 10 mg Tablet to start to work: Isoros 10 mg Tablet ideally shows its action within 1 to 4 hours after administration. The time for which the effects of Isoros 10 mg Tablet last: The effect of Isoros 10 mg Tablet lasts for 5 days.

What if you forget to take Isoros 10 mg Tablet

Skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

Store Isoros 10 mg Tablet capsules at room temperature, between 68°F and 77°F (20°C to 25°C). •Keep the capsules in their original packaging to protect them from light and moisture.

Drug Warnings

  • Do not share this medicine with anyone else, even if they have similar severe acne symptoms, as it can cause severe harm, especially to unborn babies.
  • Do not donate blood while taking  Isoros 10 mg Tablet and for at least one month after your final dose to ensure none of your blood is given to a pregnant woman.
  • Avoid consuming alcohol while on this medicine, as both alcohol and the medication are processed by the liver, and combining them increases the risk of liver damage.
  • Do not get pregnant while taking this medicine. Women of childbearing age must use two effective forms of birth control simultaneously and undergo monthly pregnancy tests before, during, and for one month after treatment.
  • Be cautious when driving or operating machinery at night, as this medicine can cause sudden decreases in night vision.
  • Do not use Isoros 10 mg Tablet longer than prescribed. Regular follow-up appointments help your doctor decide how long treatment should continue and whether dose adjustments are needed.
  • Men taking Isoros 10 mg Tablet should discuss contraception and family planning with their doctor. Although the risk to a partner is much lower than with pregnancy in women taking the medicine, avoiding pregnancy during treatment is still recommended.
  • Complete all recommended blood tests and follow-up visits during treatment, even if your acne is improving.
     

Drug-Drug Interactions

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Drug-Drug Interactions:

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Tetracycline antibiotics: Taking these with  Isoros 10 mg Tablet increases the risk of high pressure inside the skull, which can cause severe headaches and vision loss.
  • Vitamin A supplements: Combining these can lead to additive toxic effects, similar to a severe Vitamin A overdose.
  • Progesterone-only birth control pills: This medicine may reduce the effectiveness of these specific contraceptives. Use two robust forms of birth control as directed.
  • Systemic corticosteroids: May increase the risk of bone loss or weak bones when combined.

Drug-Food Interactions:

  • High-fat meals: Taking  Isoros 10 mg Tablet with fatty foods significantly increases its absorption and effectiveness. Do not take it on an empty stomach unless specifically instructed.

Drug-Disease Interactions:

Inform your doctor if you have a history of the following conditions before taking  Isoros 10 mg Tablet , as it may worsen your condition or cause complications.

  • Liver disease: Do not take this medicine if you have severe liver impairment, as it can cause further liver damage.
  • High blood lipids: This medicine can increase blood fat levels (cholesterol and triglycerides). Your doctor will monitor your blood lipids closely if you have high cholesterol.
  • Depression or mental health conditions: Let your doctor know if you have a history of depression or mood disorders, as this medicine can occasionally worsen these conditions.
     
IsotretinoinDemeclocycline
Critical

Drug-Drug Interactions

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How does the drug interact with Isoros 10 mg Tablet:
Co-administration of Isoros 10 mg Tablet with Oxytetracycline can increase the risk of pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Isoros 10 mg Tablet and Oxytetracycline together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting doctor.
IsotretinoinDemeclocycline
Critical
How does the drug interact with Isoros 10 mg Tablet:
Taking Isoros 10 mg Tablet with Demeclocycline may increase the risk of a rare and serious condition called pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking Isoros 10 mg Tablet and Demeclocycline together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting doctor.
How does the drug interact with Isoros 10 mg Tablet:
Taking Isoros 10 mg Tablet with Doxycycline may increase the risk of a rare condition called pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking Isoros 10 mg Tablet and Doxycycline together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting doctor.
IsotretinoinAminolevulinic acid
Severe
How does the drug interact with Isoros 10 mg Tablet:
Taking Isoros 10 mg Tablet with aminolevulinic acid may increase the risk of a severe sunburn.

How to manage the interaction:
Although taking Isoros 10 mg Tablet and aminolevulinic acid together can possibly result in an interaction, it can be taken if your doctor has prescribed it. After taking you should avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours. Incase you experience any unusual symptoms, consult a doctor. Do not stop using any medications without consulting doctor.
How does the drug interact with Isoros 10 mg Tablet:
Taking Isoros 10 mg Tablet with teriflunomide may affect liver and causes liver problems.

How to manage the interaction:
Although taking Isoros 10 mg Tablet and teriflunomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, light-coloured stools, and/or yellowing of the skin or eyes. Do not stop using any medications without consulting doctor.
How does the drug interact with Isoros 10 mg Tablet:
Taking Isoros 10 mg Tablet with minocycline may increase the risk of a rare and serious condition called pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking Isoros 10 mg Tablet and minocycline together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting a doctor.
IsotretinoinLomitapide
Severe
How does the drug interact with Isoros 10 mg Tablet:
Taking Isoros 10 mg Tablet with lomitapide may affect liver and cause liver problems.

How to manage the interaction:
Although taking Isoros 10 mg Tablet and lomitapide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Isoros 10 mg Tablet:
Taking Isoros 10 mg Tablet together with tretinoin may increase the risk of hypervitaminosis A (excessive vitamin A-related effects).

How to manage the interaction:
Although taking Isoros 10 mg Tablet and tretinoin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as increased pressure in the brain (headache, nausea, vomiting, visual disturbances) or liver damage (fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, yellowing of the skin or eyes). Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[RETINOIDS]

FAQs

Isoros 10 mg Tablet is used to treat a severe form of acne known as nodular acne that cannot be cleared by any other treatments, including antibiotics.

Isoros 10 mg Tablet may cause decreased night vision temporarily or permanently in some patients. It is not necessary for everyone taking Isoros 10 mg Tablet to experience this side effect. Avoid driving after taking Isoros 10 mg Tablet if you are unable to see in the dark, and consult a doctor if you notice any changes in vision or have painful or persistent dry eyes.

Isoros 10 mg Tablet may increase the skin sensitivity to sunlight. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen and wear protective clothing while going out to prevent sunburn.

No, you are not recommended to undergo any cosmetic procedures to smoothen your skin, including waxing, laser procedures or dermabrasion (an exfoliating technique to remove outer layers of skin with a rotating instrument) while taking Isoros 10 mg Tablet and for a minimum of 6 months after stopping treatment with Isoros 10 mg Tablet , as it may increase the risk of scarring.

You are not recommended to take vitamin A supplements with Isoros 10 mg Tablet as it may cause hypervitaminosis A (excessive levels of vitamin A in the body), leading to an increased risk of adverse effects. However, please consult a doctor before taking other medicines or supplements with Isoros 10 mg Tablet .

Isoros 10 mg Tablet is safe to use if prescribed by the doctor. Use Isoros 10 mg Tablet exactly as advised by the doctor as it is associated with adverse effects.

Isoros 10 mg Tablet is not a steroid. It is a retinoid used to treat severe nodular acne.

Pregnancy tests, lipid profile tests, liver function tests, blood glucose tests, and creatine phosphokinase (CPK) tests are recommended tests during Isoros 10 mg Tablet treatment.

In most cases, the effect of Isoros 10 mg Tablet is permanent. Isotretinoin is a clinically effective anti-acne therapy that shows significant improvement in many patients.

Isoros 10 mg Tablet does not cause cancer. In fact, isotretinoin slows the growth of cancer cells by activating protein receptors in cells, including cancer cells.

Long-term use of Isoros 10 mg Tablet , even in low doses, has not been studied and is not recommended. Hence, long-term side effects of Isoros 10 mg Tablet have not been established.

Isoros 10 mg Tablet is not known to affect male fertility.

Isoros 10 mg Tablet might elevate liver enzymes. Therefore, regular liver function tests are advised.

Side effects of Isoros 10 mg Tablet include chapped lips and dry skin, eyes, nose, or lips. These side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

No, you must not get pregnant while taking Isoros 10 mg Tablet . It causes severe, life-threatening birth defects. Women who can get pregnant must use two effective forms of birth control and have regular pregnancy tests. Talk to your doctor if you have questions about birth control.

Taking Isoros 10 mg Tablet with a meal, especially one containing healthy fats, helps your body absorb the medicine properly. If taken on an empty stomach, the medicine may not work as effectively. Talk to your doctor or pharmacist for specific meal advice.

Most people begin to notice improvement within 1 to 2 months of starting Isoros 10 mg Tablet . During the first few weeks, your acne may temporarily become worse before it starts improving. This early flare is usually temporary, but you should inform your doctor if it becomes severe. A typical treatment course lasts about 4 to 6 months, although the duration may vary depending on your response and your doctor's advice.

It is highly recommended to avoid alcohol while taking Isoros 10 mg Tablet . Both alcohol and this medicine are processed by your liver, and combining them increases the risk of liver damage and elevated blood fats. Talk to your doctor for advice.

No, you should avoid waxing, laser treatments, and chemical peels while taking Isoros 10 mg Tablet and for at least six months after stopping. The medicine makes your skin highly fragile, increasing the risk of severe skin irritation, tearing, and scarring. Talk to your dermatologist.

Yes, dryness of the skin, lips, eyes, and nose is the most common side effect of Isoros 10 mg Tablet . You can manage this by using thick moisturizers, lip balms, and lubricating eye drops regularly. Talk to your pharmacist for product recommendations.

No, you must not donate blood while taking Isoros 10 mg Tablet and for at least one month after you stop taking it. This precaution prevents the risk of your blood being given to a pregnant woman, which could cause severe birth defects. Talk to your doctor for more information.

If you or your family notice any unusual mood changes, severe sadness, anxiety, or thoughts of self-harm while taking Isoros 10 mg Tablet , stop taking the medicine immediately and contact your healthcare provider. Talk to your doctor right away if you experience these symptoms.

Yes, your doctor may recommend blood tests before and during treatment to monitor your liver function and blood fat levels such as cholesterol and triglycerides. Some patients may also require other tests depending on their health history. These checks help ensure that the medicine remains safe and appropriate for you.

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Country of origin

India

Manufacturer/Marketer address

Godown No. B/19 Part-2, Gujrat Estate Sarkhej Sanand Road, Sarkhej Ahmedabad Ahmedabad Gj 382210 In
Other Info - ISO0342
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