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compositionComposition:LORAZEPAM-2MG
prescription
Prescription Medicine
info
Lorel-2 Tablet 10's

Lorel-2 Tablet is used to treat epilepsy (status epilepticus) and anxiety disorder. It may be prescribed as short-term therapy for sleeping difficulties due to anxiety. It may also be used as a sedative prior to surgery. It contains Lorazepam, which works by increasing levels of the calming chemical in the brain; this helps relieve anxiety, stops seizure attacks (fits) and relaxes the tense muscles. It may cause common side effects such as sleepiness, tiredness, muscle weakness and problems with coordination. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LORAZEPAM-2MG

Manufacturer/Marketer :

Reliance Formulation Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Lorel-2 Tablet

Lorel-2 Tablet is an oral prescription medicine used to treat severe anxiety and associated sleep problems. It helps calm excessive nerve activity in the brain to provide rapid relief from physical and emotional distress. This medication is typically prescribed for short-term management to prevent potential dependency.

To achieve the best results, you must take this medicine consistently and exactly as directed by your doctor. It can be taken with or without food, though taking it with a meal can help if you experience a mild upset stomach. Combining this treatment with lifestyle changes like a regular sleep schedule and stress-reduction techniques will further support your recovery.

Some people may experience common side effects such as drowsiness, tiredness, or feeling unsteady while taking Lorel-2 Tablet . These effects are usually mild, but you should contact your doctor immediately if you experience serious symptoms like extreme confusion, severe muscle weakness, or yellowing of the skin.

Talk to your doctor if you have a history of breathing disorders, kidney disease, or liver damage before starting this medication. Do not take this if you have a history of severe lung disease, sleep apnea, or severe liver damage.

This medicine can interact with alcohol, smoking, and other sedating medications because they can dangerously slow down your breathing and nervous system. You should also consult your doctor if you are pregnant, breastfeeding, or an elderly individual, as this medication requires highly cautious use in these groups.

Uses of Lorel-2 Tablet

Lorel-2 Tablet is used to treat severe anxiety and sleep problems. The detailed uses of Lorel-2 Tablet are as follows:

  • Anxiety disorders: Lorel-2 Tablet helps ease severe, persistent worry, restlessness, and physical tension.
  • Short-term insomnia: Lorel-2 Tablet helps you fall asleep faster and stay asleep when anxiety disrupts your nightly rest.
  • Panic attacks: Lorel-2 Tablet provides rapid relief from sudden, overwhelming feelings of intense fear and physical panic symptoms.
  • Pre-procedure sedation: Lorel-2 Tablet helps calm and relax patients before surgical, medical, or dental procedures.

Key Benefits

Lorel-2 Tablet provides support for managing anxiety symptoms by helping calm the nervous system and reduce physical and emotional distress. By promoting relaxation and improving symptom control, this medicine offers several key health benefits:

  • Relief from Anxiety Symptoms: Lorel-2 Tablet helps reduce overwhelming feelings of fear, worry, and nervousness, supporting greater emotional balance during periods of high stress.
  • Improved Sleep and Daily Function: By calming an overactive nervous system, Lorel-2 Tablet helps promote more restful sleep, better daytime focus, and improved overall quality of life.
  • Reduction of Physical Anxiety Symptoms: Lorel-2 Tablet helps ease symptoms such as muscle tension, rapid heartbeat, and trembling, making daily activities more comfortable.
     
Side effects of Lorel-2 Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Stay organized with calendars, planners, and sticky notes. Write in notebooks and journals to remember things. Make photo albums to trigger memories and track special events.
  • Use digital tools to help you remember like reminder apps, voice recordings, and GPS navigation
  • Improve your memory with brain exercises, memory aids, and visualization.
  • Create a daily routine and set a schedule. Use reminders and labels to stay organized and on track.
  • Get help to recall from family and friends. You can also talk to a therapist for support.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.

Directions for Use

To get the full benefit of Lorel-2 Tablet and minimise side effects, follow these simple guidelines:

  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
  • You can take this medicine with or without food, as directed by your healthcare provider.
  • Always follow your doctor's exact instructions regarding how and when to take your medication.
  • Do not stop taking this medication suddenly, as doing so can cause severe withdrawal symptoms.

How Lorel-2 Tablet Works

Lorel-2 Tablet contains lorazepam. To help you manage your health, Lorel-2 Tablet targets these body: Lorel-2 Tablet works by boosting the action of a natural chemical messenger in the brain called gamma-aminobutyric acid (GABA). GABA acts as a natural tranquilizer, slowing down overactive nerve cells in the brain and spinal cord. When anxiety or stress triggers an overstimulation of brain signals, this medication increases GABA activity to restore balance. This results in relaxed muscles, reduced feelings of fear, and a calmer state of mind.
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Alcohol

Unsafe

Avoid taking Lorel-2 Tablet with alcohol as it can increase the side effects of this medicine like dizziness, drowsiness and difficulty in concentrating.

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Pregnancy

Unsafe

Lorel-2 Tablet is considered unsafe for pregnant women. Lorel-2 Tablet may cause harmful effects on the baby (foetus), so your doctor will weigh the benefits and potential risks before prescribing it.

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Breast Feeding

Unsafe

Lorel-2 Tablet passes into the breast milk and may harm the baby. Avoid breastfeeding while taking Lorel-2 Tablet .

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Driving

Unsafe

Lorel-2 Tablet may cause sleepiness, dizziness, and drowsiness. So, it is not recommended to drive or operate machinery after taking Lorel-2 Tablet .

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Liver

Caution

Lorel-2 Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Lorel-2 Tablet to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

The safety and effectiveness of Lorel-2 Tablet in children have not been established.

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Heart

Consult your doctor

Exercise caution before using Lorel-2 Tablet in case of heart problems. Please consult your doctor if you have any concerns. Dosage adjustments may be needed based on your condition

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Geriatrics

Caution

Exercise caution before using Lorel-2 Tablet in older patients. Please consult your doctor if you have any concerns.

What if I have taken an overdose of Lorel-2 Tablet

Do not take more than the prescribed dose of Lorel-2 Tablet as it may cause overdose. The symptoms of overdose include sleepiness, slow or irregular heartbeat, uncontrolled eye movements, muscle weakness, overexcited, trouble speaking or poor coordination. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Avoid drinking alcohol completely while using this medication, as it can dangerously increase drowsiness and slow your breathing.
  • Limit your intake of caffeine, including coffee, tea, and energy drinks, as caffeine can reduce the calming effect of the medication and worsen anxiety.
  • Engage in daily relaxation practices such as deep breathing exercises, progressive muscle relaxation, or gentle yoga to help manage anxiety naturally.
  • Maintain a consistent sleep routine by going to bed and waking up at the same time each day to support the treatment of anxiety-related insomnia.

Have a query?

How Soon It Starts Working

The time required for Lorel-2 Tablet to start to work: Lorel-2 Tablet ideally shows its action within 2 hours after administration. The time for which the effects of Lorel-2 Tablet last: The effect of Lorel-2 Tablet lasts for 24 to 36 hours.

What if you forget to take Lorel-2 Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

• Store Lorel-2 Tablet oral tablets at room temperature, safely between 20°C to 25°C (68°F to 77°F). •Keep the medicine in its original container, tightly closed, to protect it from light and moisture.

Drug Warnings

  • Avoid driving, operating heavy machinery, or performing tasks that require mental alertness until you know how this medicine affects you.
  • Do not stop taking this medication suddenly; your doctor will help you by gradually decreasing your dose to prevent unpleasant withdrawal symptoms.
  • Check your prescription label carefully each time you refill to ensure you have received the correct strength and form of the medication.
  • Keep a record of when you take your doses to avoid accidentally taking more than prescribed, as this medicine can be habit-forming if used incorrectly.
  • Inform all your healthcare providers, including dentists and surgeons, that you are taking this medicine before undergoing any procedures.

 

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions:

Inform your doctor if you are taking any of the following medicines, as they may interact with Lorel-2 Tablet .

  • Opioid Pain Relievers, Sleeping Pills, or Muscle Relaxants: Taking these medicines with Lorel-2 Tablet may increase the risk of severe drowsiness, excessive sedation, slowed breathing, and other serious effects.
  • Medicines for Depression, Anxiety, or Seizures: Certain antidepressants, anti-anxiety medicines, and anticonvulsants may alter how Lorel-2 Tablet works in your body, increasing the risk of side effects or affecting its effectiveness.

Drug-Food Interactions:

  • Grapefruit or Grapefruit Juice: Consuming grapefruit or grapefruit juice may interfere with the way your body breaks down Lorel-2 Tablet , which can increase medicine levels and raise the risk of side effects.
  • Alcohol: Avoid alcohol while taking Lorel-2 Tablet , as it may worsen drowsiness, impair coordination, slow breathing, and increase the risk of serious effects such as loss of consciousness.

Drug-Disease Interactions:

Inform your doctor if you have a history of the following conditions before taking Lorel-2 Tablet , as it may worsen your condition or increase the risk of complications.

  • Breathing Problems (COPD or Sleep Apnea): This medicine may further slow breathing and should be used with caution in people with chronic breathing disorders or sleep apnea.
  • Liver or Kidney Disease: Reduced liver or kidney function may affect how the body processes and removes Lorel-2 Tablet , increasing the risk of medicine accumulation and side effects.
  • Myasthenia Gravis: This medicine may worsen muscle weakness and affect muscle control in people with myasthenia gravis.
LorazepamRemifentanil
Severe
LorazepamTapentadol
Severe

Drug-Drug Interactions

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LorazepamRemifentanil
Severe
How does the drug interact with Lorel-2 Tablet:
Using Lorel-2 Tablet together with Remifentanil can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness, possibly leading to coma or death).

How to manage the interaction:
Taking Lorel-2 Tablet with Remifentanil together can result in an interaction, but it can be taken if your doctor has advised it. It's important to keep an eye on your health and talk to a doctor about any concerns. They can recommend different options that won't cause any problems. If you notice any discomfort like pain, feeling dizzy, or having trouble focusing, make sure to reach out to a doctor right away. Do not stop using any medications without talking to a doctor.
LorazepamTapentadol
Severe
How does the drug interact with Lorel-2 Tablet:
Using Lorel-2 Tablet together with Tapentadol can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Lorel-2 Tablet with Tapentadol is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of dizziness, lightheadedness, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LorazepamDroperidol
Severe
How does the drug interact with Lorel-2 Tablet:
Coadministration of Lorel-2 Tablet with Droperidol can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Lorel-2 Tablet and Droperidol, you can take these medicines together if prescribed by your doctor. If you notice that your heart is beating very slowly, your blood pressure is low, or your heart rhythm feels irregular, it's important to contact a doctor right away. Also, if you suddenly feel dizzy, lightheaded, or faint, or if your heartbeat doesn't feel normal, don't hesitate to reach out to a doctor for help. Do not stop using any medications without talking to a doctor.
LorazepamDezocine
Severe
How does the drug interact with Lorel-2 Tablet:
Using Lorel-2 Tablet together with Dezocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness, possibly leading to coma or death).

How to manage the interaction:
Although there is a possible interaction between Lorel-2 Tablet and Dezocine, you can take these medicines together if prescribed by your doctor. It's important to keep an eye on your health and talk to your doctor about any concerns. If you notice any symptoms like trouble breathing, pain, feeling dizzy or tired, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
LorazepamKetamine
Severe
How does the drug interact with Lorel-2 Tablet:
Using Lorel-2 Tablet together with Ketamine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness, possibly leading to coma or death).

How to manage the interaction:
There may be a possibility of interaction between Ketamine and Lorel-2 Tablet, but it can be taken if prescribed by a doctor. If you feel dizzy, sleepy, confused, have trouble focusing, feel too relaxed, or have trouble breathing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
LorazepamBumetanide
Severe
How does the drug interact with Lorel-2 Tablet:
Coadministration of Lorel-2 Tablet with Bumetanide shows additive effects and results in low blood pressure.

How to manage the interaction:
Although taking Lorel-2 Tablet with Bumetanide together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice headache, dizziness, lightheadedness, fainting, or irregular pulse or heart rate, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LorazepamEsketamine
Severe
How does the drug interact with Lorel-2 Tablet:
Using Esketamine together with Lorel-2 Tablet may increase side effects such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination.

How to manage the interaction:
Although taking Lorel-2 Tablet and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. If you're having trouble with feeling sleepy, confused or finding it hard to focus, it's important to let a doctor know right away. They may have other options for you that won't cause these problems. Do not discontinue any medications without consulting a doctor.
LorazepamFlumazenil
Severe
How does the drug interact with Lorel-2 Tablet:
Co-administration of flumazenil with Lorel-2 Tablet can increase the risk of seizures(fits).

How to manage the interaction:
Although there is a possible interaction between Flumazenil and Lorel-2 Tablet, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
LorazepamAlfentanil
Severe
How does the drug interact with Lorel-2 Tablet:
Using narcotic pain or cough medications together with other medications that also cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
There may be a possibility of interaction between Lorel-2 Tablet and Alfentanil, but it can be taken if prescribed by a doctor. It's important to keep an eye on your health. Your doctor can recommend other options that won't cause any problems. If you notice any of these signs - feeling sad, having trouble breathing, feeling dizzy or sleepy, or finding it hard to focus - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
LorazepamMorphine
Severe
How does the drug interact with Lorel-2 Tablet:
Using Lorel-2 Tablet together with Morphine can increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Co-administration of Morphine with Lorel-2 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

Yes

Therapeutic Class

[SEDATIVE-HYPNOTIC DRUGS]

FAQs

Lorel-2 Tablet is used to treat epilepsy (status epilepticus) and anxiety disorder. It may also be prescribed as short-term therapy for sleeping difficulties due to anxiety and as a sedative prior to surgery.
Lorel-2 Tablet works by increasing levels of the chemical mediator which calms brain cells (neurons), known as gamma-aminobutyric acid (GABA), thus helps relieve anxiety.
Elderly patients are more likely to have confusion and sleepiness or age-related health issues, which may require caution and an adjustment in the dose. Consult your doctor if you have any concerns.
Yes, this medicine has the potential to cause physical or psychological dependence, especially if taken for a long period or at high doses. Your doctor will monitor your treatment carefully to prevent this. Talk to your doctor about how to use this medicine safely.
If you have taken a double dose or overdosed on Lorel-2 Tablet , you need immediate medical help. Call your doctor or go to the nearest hospital or clinic.
No, Lorel-2 Tablet is not an opioid. It belongs to the group of medications called benzodiazepines used for the treatment of epilepsy and anxiety disorders.
Yes, drowsiness is a common side effect of this medicine, especially when you first start taking it or when your dose is increased. Avoid driving or operating machinery if you feel drowsy. Talk to your doctor if this sleepiness interferes with your daily activities.
Lorel-2 Tablet will stay in our body's system for 12 hours.
If you get addicted to Lorel-2 Tablet , you might experience symptoms like, withdrawal symptoms like anxiety, tremors, insomnia, intense cravings and increased tolerance. Seek emergency medical help if you experience these symptoms.
Lorel-2 Tablet is not known to cause weight gain. However, you may experience weight changes due to loss of appetite.
Yes, Lorel-2 Tablet may cause depression if you suddenly stop taking it. Hence, continue taking this medicine for a prescribed period.
Yes, Lorel-2 Tablet may affect memory, particularly in older persons. Consult the doctor before taking Lorel-2 Tablet if you have any queries.
Lorel-2 Tablet can cause CNS and respiratory depression if Lorel-2 Tablet is taken more than the recommended dose, potentially leading to hypotension, extreme drowsiness, muscle weakness, confusion, ataxia and coma. Therefore, always follow the dose prescribed by the doctor based on your medical condition.
No, you should not drink alcohol while taking this medicine. Alcohol increases the sedative effects of the medication, which can lead to severe drowsiness, breathing problems, and even loss of consciousness. Talk to your doctor if you have concerns about alcohol use.
This medicine is generally not recommended during pregnancy as it can potentially harm the developing baby. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor to discuss safer alternatives.
The oral form of this medicine usually begins working within 20 to 30 minutes after taking it. It reaches its peak effect within 1 to 2 hours. Talk to your doctor if you do not feel any improvement in your symptoms.
ou should never stop taking this medicine suddenly, as this can cause withdrawal symptoms like anxiety, sweating, tremors, or sleep problems. Your doctor will guide you in gradually decreasing your dose. Talk to your doctor before making any changes.
Yes, you can take this medicine with or without food. If you find that it causes a mild upset stomach, taking it with a light meal or snack may help. Talk to your doctor or pharmacist for more personalized advice.
Take the missed dose as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your normal routine. Never take two doses at the same time. Talk to your doctor if you regularly miss doses.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. National Center for Biotechnology Information (NCBI). Nbk532890 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Drugs.com Clinical Review Team. Lorazepam Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  3. National Health Service (NHS). Lorazepam - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  4. Lorazepam [Prescribing Information]. 2025. [Accessed on 18 Jun. 2025] Check here
  5. DailyMed - ATIVAN- lorazepam tablet [Internet]. Nih.gov. [Accessed on 2025 Nov 21] Check here
  6. Lorazepam: Worsening of delirium: 3 case reports. React Wkly [Internet]. 2017 [Accessed on 2025 Nov 21] Check here
  7. NIH National Library of Medicine, National center for biotechnology information. PubChem. Lorazepam. [Accessed on 4th April 2024]Check here

Country of origin

INDIA

Manufacturer/Marketer address

Dhirubhai Ambani Life Sciences Centre, R-282, TTC Area of MIDC, Thane-Belapur Road, Rabale, Navi Mumbai 400 701
Other Info - LOR0236

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