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compositionComposition:METHOXSALEN-1%W/V
prescription
Prescription Medicine
info
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Melcyl Lotion is used to treat Psoriasis (scaly, itchy, and red patches on the skin) and vitiligo (discoloured patches in different body areas, including the skin and hair). It contains methoxsalen, which is used alongside ultraviolet-A radiation. It works by reducing the number of cells the skin makes. If you are pregnant or planning pregnancy or nursing mother, please inform your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

METHOXSALEN-1%W/V

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Melcyl Lotion

Melcyl Lotion is a specialised topical medication used to treat severe skin conditions such as psoriasis and vitiligo. It is designed to work in combination with ultraviolet light therapy to help clear skin lesions and restore natural skin pigment. This treatment is typically reserved for cases that have not responded to other therapies.

Because of how it works, Melcyl Lotion is not for daily use at home. It is applied consistently according to a strict schedule, usually just before a planned light therapy session in a clinical setting. While food intake does not directly affect how this topical treatment is absorbed, making certain lifestyle adjustments, such as protecting your skin from unexpected sun exposure, is essential for getting the best results.

Like all medical treatments, this medication can cause side effects. Most commonly, patients experience temporary skin redness, itching, or a mild burning sensation. However, you should consult your doctor immediately if you experience severe skin blistering, intense pain, or signs of an allergic reaction.

Do not use this medication if you are highly sensitive to sunlight, have a history of skin cancer, or lack the natural lens in your eye. Before starting treatment, tell your doctor if you have liver damage, kidney disease, or any conditions that make you sensitive to light.

Certain medications, such as some water pills or antibiotics, can increase your skin's sensitivity to light and should not be used alongside this treatment. It is also wise to limit alcohol consumption as it can dry out and irritate your skin. Always consult your healthcare provider if you are pregnant, breastfeeding, or an older adult, as special precautions may be needed.

Uses of Melcyl Lotion

Melcyl Lotion is used in the treatment of Psoriasis and vitiligo. The detailed uses of Melcyl Lotion are as follows:

  • Severe psoriasis: Helps clear up thick, scaly skin plaques by slowing down the overactive growth of skin cells when activated by controlled light therapy.
  • Vitiligo: Works to restore natural skin colour in areas that have lost pigment by stimulating pigment-producing cells in the skin.
  • Cutaneous T-cell lymphoma (CTCL): In selected patients, methoxsalen may be used with specialised UVA (PUVA) therapy under the close supervision of a dermatologist or cancer specialist.

Key Benefits

Melcyl Lotion offers significant, visible relief for patients dealing with stubborn skin conditions.

Benefits may include:

  • By targeting only the affected areas of the skin, it provides a highly focused treatment approach that limits the risk of body-wide side effects often seen with oral medications.
  • When combined with light therapy, it helps speed up the clearing of painful, itchy plaques, leading to smoother skin and greater physical comfort.
  • For those with vitiligo, it can help restore lost skin tone, helping patients feel more comfortable and confident in their skin.
Side effects of Melcyl Lotion 30 ml
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Directions for Use

  • Follow your doctor’s instructions regarding the dosage and duration.
  • A physician will apply Melcyl Lotion only to a well-defined area of skin before the area is exposed to ultraviolet light A (UVA).
  • Wash the treated area of skin with soap and water after UVA exposure.

How Melcyl Lotion Works

Melcyl Lotion belongs to a group of medicines known as photosensitizers. On its own, the topical solution does not cause active skin changes. Instead, it sits quietly in the skin cells after application. When those cells are exposed to prescribed ultraviolet (UVA) light, the medicine becomes active. Once activated, it binds to the DNA of the abnormal skin cells. In conditions like psoriasis, this action slows down the rapid, uncontrolled division of cells that leads to thick, scaly plaques. In vitiligo, the combination of the medicine and light stimulates the cells that produce skin pigment, helping to darken the pale patches and blend them with your natural skin tone.
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Alcohol

Caution

The interaction of Melcyl Lotion with alcohol is unknown. Please discuss with your doctor if you have any concerns.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, please inform your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

If you are breastfeeding, inform your doctor before using Melcyl Lotion. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Safe

Melcyl Lotion usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Please inform your doctor if you have any liver diseases/conditions.

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Kidney

Consult your doctor

Please inform your doctor if you have any kidney diseases/conditions.

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Children

Consult your doctor

The safety of Melcyl Lotion in children has not been established. However, please consult a doctor if you have any concerns regarding this.

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Heart

Consult your doctor

Please inform your doctor if you have any heart diseases/conditions.

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Geriatrics

Caution

Melcyl Lotion should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of Melcyl Lotion

If you apply too much solution, wash it off immediately with cool water and soap. If the medication is accidentally swallowed, or if you expose your skin to sunlight after a heavy application, seek immediate emergency medical care. Overexposure can lead to severe, painful skin burns.

Diet & Lifestyle Advise

  • Block all UV light: Keep treated skin completely covered with thick, tightly woven clothing, a wide-brimmed hat, and wrap-around sunglasses that block UVA rays for at least 24 hours after application.
  • Apply sunscreen: Use a broad-spectrum sunscreen with an SPF of 30 or higher on all exposed skin, even when staying indoors near windows.
  • Moisturise safely: Keep untreated skin hydrated with a gentle, fragrance-free moisturiser to prevent overall skin dryness, but avoid putting anything on the treated areas unless approved by your doctor.
  • Stay hydrated: Drink plenty of water daily to support overall skin health and healing during your treatment course.
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How Soon It Starts Working

The time required for Melcyl Lotion to start to work: Melcyl Lotion ideally shows its action within 30 minutes of administration. The time for which the effects of Melcyl Lotion last: The duration of action for Melcyl Lotion is unknown.

What if you forget to take Melcyl Lotion

If you miss an application or a scheduled light therapy session, contact your doctor or clinic right away to reschedule. Do not try to apply extra solution at home or make up for the missed session on your own.

Storage

• Store Melcyl Lotion topical solution at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Inspect the solution: Always inspect the liquid before applying it; do not use it if it looks cloudy, is discoloured, or contains floating particles.
  • Avoid hot water: Avoid taking hot baths or showers immediately before or after your application, as hot water can increase skin sensitivity and absorption.
  • Apply only to affected skin: Never apply this medicine to healthy skin, as doing so makes that skin highly vulnerable to painful sunburns.
  • Keep your appointments: Keep all your clinic appointments strictly, as the timing between your topical application and the light therapy is vital for your safety.
  • Avoid other skin products: Do not apply any other creams, oils, or cosmetic products to the treated area unless your doctor has specifically told you it is safe to do so.

Drug-Drug Interactions

verifiedApollotooltip
  • Other photosensitising drugs (like tetracyclines, sulfa antibiotics, or certain water pills): Can significantly increase your skin's sensitivity to light, raising the risk of severe burns.
  • Other topical skin treatments (like coal tar or anthralin): May increase irritation and skin sensitivity when applied to the same areas.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Melcyl Lotion when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIPSORIATICS]

FAQs

Melcyl Lotion is used to treat Psoriasis (scaly, itchy, and red patches on the skin), and vitiligo (discoloured patches in different areas of the body, including the skin and hair).
Melcyl Lotion contains methoxsalen, which works by reducing the number of cells the skin makes. It is used alongside ultraviolet-A radiation.
Melcyl Lotion may increase skin sensitivity to sunlight. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen and wear protective clothing while going out to prevent sunburn. Also, avoid sunbathing anytime during the course of treatment with Melcyl Lotion.
Melcyl Lotion may cause premature ageing of the skin as a result of prolonged therapy. This effect is similar to the result of sunbathing for a long duration.
No, you must avoid sunlight and artificial UV light for at least 24 hours after application because your skin will be highly sensitive and can burn easily. Talk to your doctor for specific safety steps.
It typically takes several weeks of regular treatments combined with light therapy to see visible improvements in your skin. Talk to your doctor about your specific treatment plan.
You should only apply this medicine to the exact areas designated by your doctor. Avoid applying it near your eyes, mouth, or nostrils. Talk to your doctor if you have concerns about facial lesions.
If you notice severe redness, pain, or blistering, contact your healthcare provider immediately. Do not try to treat severe burns with home remedies without medical guidance. Talk to your doctor right away.
You can use gentle moisturisers on untreated skin, but avoid applying anything to the treated areas unless your doctor tells you to. Talk to your doctor or pharmacist for safe recommendations.
This medication is generally not recommended during pregnancy as it may cause harm. Talk to your doctor to discuss safer treatment options if you are pregnant or planning to become pregnant.
Melcyl Lotion makes your eyes more sensitive to ultraviolet (UVA) light. Wearing wrap-around sunglasses that block UVA rays helps protect your eyes from light-induced retinal damage, especially if you have aphakia (absence of the eye's natural lens). Follow your doctor's instructions on how long to wear eye protection after treatment.
This medicine is usually applied by a healthcare provider in a clinic to ensure safe timing before light therapy. If you are told to apply it at home, you must follow the instructions exactly. Talk to your doctor for clarification.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

6, Nandalal Bose Sarani,Kolkata -700071.
Other Info - MEL0400

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