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Puvalen 1% Lotion 30 ml belongs to the class of drugs called psoralens (light-sensitive drugs) used along with controlled ultraviolet light in a treatment called psoralen plus ultraviolet light A (PUVA) to treat skin conditions such as vitiligo and psoriasis. Psoriasis is a skin disorder in which skin cells multiply and form bumpy (uneven) red patches covered with white scales. Vitiligo is a skin condition that causes loss of skin colour in blotches when melanocytes (cells that produce the colour) do not produce skin pigment, melanin (that gives the skin colour).
Puvalen 1% Lotion 30 ml contains methoxsalen, which is used alongside ultraviolet-A radiation. It works by reducing the number of cells the skin makes.
Puvalen 1% Lotion 30 ml is for external use only. Some people may experience itching or skin irritation. Most of these side effects of Puvalen 1% Lotion 30 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Methoxsalen or any other medicines, please inform your doctor. If you are pregnant or a nursing mother, it is advised to inform your doctor before using Puvalen 1% Lotion 30 ml. After UVA exposure, you are recommended to wash the treated area of the skin with soap and water. Then use sunscreen or wear protective clothing to protect the treated area. If you have squamous cell cancer (a form of skin cancer) or melanoma (a serious type of skin cancer), please inform your doctor beforehand.
Puvalen 1% Lotion 30 ml used in the treatment of Psoriasis (scaly, itchy, and red patches on the skin), and vitiligo (discoloured patches in different areas of the body, including the skin and hair). The detailed uses of Puvalen 1% Lotion 30 ml are as follows:
Puvalen 1% Lotion 30 ml contains methoxsalen, used along with controlled ultraviolet light in a treatment called psoralen plus ultraviolet light A (PUVA) to treat skin conditions such as vitiligo (discoloured patches in different areas of the body, including the skin and hair) and psoriasis (scaly, itchy, and red patches on the skin). It is used alongside ultraviolet-A radiation. It works by reducing the number of cells the skin makes.
Caution
The interaction of Puvalen 1% Lotion 30 ml with alcohol is unknown. Please discuss with your doctor if you have any concerns.
Consult your doctor
If you are pregnant or planning pregnancy, please inform your doctor. Your doctor will prescribe only if the benefits outweigh the risks.
Consult your doctor
If you are breastfeeding, inform your doctor before using Puvalen 1% Lotion 30 ml. Your doctor will prescribe only if the benefits outweigh the risks.
Safe
Puvalen 1% Lotion 30 ml usually does not affect your ability to drive or operate machinery.
Consult your doctor
Please inform your doctor if you have any liver diseases/conditions.
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Please inform your doctor if you have any kidney diseases/conditions.
Consult your doctor
The safety of Puvalen 1% Lotion 30 ml in children has not been established. However, please consult a doctor if you have any concerns regarding this.
Consult your doctor
Please inform your doctor if you have any heart diseases/conditions.
Caution
Puvalen 1% Lotion 30 ml should be used with caution in elderly patients. Please consult your doctor before use.
Vitiligo:
Minimize sun exposure. Use sunscreen with high SPF and protective sunglasses while going out in the sun.
Prefer using self-tanning lotions as they may help to even out skin tone and the effect lasts longer, even with washing.
Psoriasis:
Increase your intake of lean proteins containing omega-3 fatty acids, such as sardines, salmon, shrimp, flax seeds, walnuts and soybeans.
Avoid foods such as refined sugar, red meat, dairy products and highly processed foods, as these might trigger inflammation.
Avoid alcohol consumption as it may increase the risk of flare-ups.
Stress can also trigger psoriasis. Therefore, learn to manage and cope with stress by doing yoga, breathing, meditation, and journaling.

Have a query?
Please inform your doctor if you are allergic to Methoxsalen or any other medicines. If you are pregnant or a nursing mother, it is advised to inform your doctor before using Puvalen 1% Lotion 30 ml. After UVA exposure, you are recommended to wash the treated area of your skin with soap and water. Then use sunscreen or wear protective clothing to protect the treated area. If you have squamous cell cancer (a form of skin cancer) or melanoma (a serious type of skin cancer), please inform your doctor beforehand. Wear special sunglasses during and for 24 hours after the treatment.
Drug-Drug Interaction: Inform your doctor if you are receiving concomitant therapy with photosensitizing agents (anthralin/dithranol, coal tar or its derivatives, phenothiazines, thiazides, griseofulvin, nalidixic acid, sulphonamides, salicylanilides, tetracyclines) and certain organic staining dyes (toluidine blue, methylene blue, methyl orange and rose Bengal).
Drug-Food Interaction: Avoid eating figs, parsley, mustard, parsnips, carrots, limes, and celery while being treated with Puvalen 1% Lotion 30 ml, as these may increase the skin’s sensitivity to sunlight.
Drug-Disease Interaction: Puvalen 1% Lotion 30 ml is contraindicated in patients with aphakia (missing lens inside the eye). If you have a specific history of light-sensitive disease states such as erythropoietic protoporphyria (rare inherited metabolic disorder), lupus erythematosus (autoimmune disease), xeroderma pigmentosum (extreme sensitivity to UV rays), variegate porphyria (inherited porphyria), albinism (group of genetic disorders that causes hair, skin or eyes to have little or no colour) and porphyria cutanea tarda (a type of blood disorder that affects the skin), please inform your doctor.
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Puvalen 1% Lotion 30 ml is used to treat Psoriasis (scaly, itchy, and red patches on the skin), and vitiligo (discoloured patches in different areas of the body, including the skin and hair).
Puvalen 1% Lotion 30 ml contains methoxsalen, which works by reducing the number of cells the skin makes. It is used alongside ultraviolet-A radiation.
Puvalen 1% Lotion 30 ml may increase skin sensitivity to sunlight. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen and wear protective clothing while going out to prevent sunburn. Also, avoid sunbathing anytime during the course of treatment with Puvalen 1% Lotion 30 ml.
Puvalen 1% Lotion 30 ml may cause premature ageing of the skin as a result of prolonged therapy. This effect is similar to the result of sunbathing for a long duration.
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