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compositionComposition:DECAPEPTIDE-1MG
prescription
Prescription Medicine
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Melgain Lotion 5 ml is a depigmenting agent used in the treatment of vitiligo. This medicine contains decapeptide, which induces the proliferation of melanin-producing cells (melanocytes) in white depigmented patches of skin and roots of the hair, thus helping treat vitiligo. You may experience side effects like skin irritation, dry skin, burning sensation.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

DECAPEPTIDE-1MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Melgain Lotion 5 ml

Melgain Lotion 5 ml is a topical skin-care preparation used to treat hyperpigmentation, uneven skin tone, and dark patches such as sun spots or melasma. It works by targeting the biological pathways that produce excess skin pigment, helping to gradually lighten dark areas. By correcting uneven pigment distribution, this treatment supports a clearer, more balanced complexion.

For the best results, you should apply Melgain Lotion 5 ml consistently once or twice daily, as directed by your healthcare provider. Because this is a topical cream, it does not require any dietary restrictions and can be applied without regard to meals. To support the effects of this topical care, it is highly recommended to wear broad-spectrum sunscreen daily and limit direct sun exposure, which can trigger more pigment production.

While using Melgain Lotion 5 ml, some people may experience mild, temporary skin reactions like dryness, flaking, or slight redness. If you experience severe burning, persistent itching, or signs of an allergic reaction, stop applying it immediately and consult your doctor. Most side effects are minor and resolve as your skin adjusts to the treatment.

Before starting this medication, talk to your doctor if you have active skin conditions like eczema, psoriasis, or open wounds on the treatment area. Do not use this product if you have a known allergy to any of its ingredients. It is always safest to have a healthcare professional evaluate your skin before beginning a new regimen.

If you are using other prescription topical treatments, such as retinoids or peeling agents, discuss this with your doctor to avoid excessive skin irritation. Pregnant or breastfeeding women, elderly individuals with fragile skin, and children or adolescents should consult their healthcare provider before using this topical product, as safety and effectiveness may vary depending on age and the underlying skin condition.

Uses of Melgain Lotion 5 ml

Melgain Lotion 5 ml is used to help manage the following skin concerns:

  • Hyperpigmentation: Melgain Lotion 5 ml helps fade dark patches, age spots, and sun spots by regulating excess pigment production in the skin cells.
  • Melasma: This topical product lightens the stubborn, symmetric brown patches that commonly appear on the face due to hormonal changes or sun exposure.
  • Uneven skin tone: It helps smooth out blotchy skin discolouration, promoting a more uniform and balanced complexion over time.

Key Benefits

The following are the benefits of using Melgain Lotion 5 ml regularly:

  • Fades existing pigmentation: Gradually reduces the appearance of dark patches, age spots, and uneven pigmentation to promote a clearer, more even-looking complexion.
  • Supports an even skin tone: Helps improve overall skin uniformity by reducing blotchy discolouration and enhancing the skin's natural appearance.
  • Helps prevent new dark spots: Regulates excess pigment production to reduce the likelihood of new areas of hyperpigmentation developing with continued use.
  • Provides gentle pigment correction: Offers a milder approach to managing skin discolouration, helping minimise the risk of excessive peeling or damage to the skin barrier compared with harsher depigmenting treatments.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Apply a small amount of Melgain Lotion 5 ml as a thin layer and gently rub it on the clean and dry affected area of the skin.
  • Melgain Lotion 5 ml is for external use only.
  • Avoid contact of the Melgain Lotion 5 ml with the nose or eyes. In case of accidental contact with these areas, thoroughly rinse them with water.

How Melgain Lotion 5 ml Works

Melgain Lotion 5 ml contains a skin-brightening peptide that helps reduce skin discolouration and promote a more even skin tone. Research suggests that decapeptide may help reduce the activity of tyrosinase, a key enzyme involved in melanin production. By helping regulate melanin production, it may gradually reduce the formation of excess pigment responsible for dark spots and uneven skin tone. When the skin produces excess melanin due to factors such as sun exposure, hormonal changes, or inflammation, dark spots and uneven pigmentation can develop. Visible improvement may take several weeks of consistent use, with results varying depending on the severity of pigmentation, individual skin characteristics, and regular sun protection. With regular use, older, heavily pigmented skin cells are naturally replaced by new skin cells with a more even distribution of pigment. This gradually helps fade dark spots, improve skin clarity, and promote a brighter, more uniform complexion. Together, these actions help reduce hyperpigmentation, minimise the appearance of dark spots, and improve overall skin tone.
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Alcohol

Caution

No interactions were found/established.

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Pregnancy

Caution

The safety of Melgain Lotion 5 ml during pregnancy has not been established. Please seek medical advice before using the Melgain Lotion 5 ml.

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Breast Feeding

Caution

The safety of Melgain Lotion 5 ml during lactation has not been established. Please seek medical advice before using the Melgain Lotion 5 ml.

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Driving

Safe if prescribed

Melgain Lotion 5 ml has no or negligible influence on the ability to drive or use machines.

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Liver

Safe if prescribed

No interactions were found/established.

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Kidney

Safe if prescribed

No interactions were found/established.

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Children

Caution

Limited research is available on the use of Melgain Lotion 5 ml in children. So, please do not use Melgain Lotion 5 ml in children without a doctor's advice.

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Heart

Safe if prescribed

Melgain Lotion 5 ml is generally considered safe for individuals with heart conditions. However, please consult your doctor if you have any concerns.

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Geriatrics

Safe if prescribed

Melgain Lotion 5 ml is generally considered safe for elderly patients when prescribed by a doctor. Seek medical advice if you have any concerns.

What if I have taken an overdose of Melgain Lotion 5 ml

Because Melgain Lotion 5 ml is applied to the skin, an accidental topical overdose is unlikely to cause serious harm, although applying excessive amounts may lead to significant skin irritation, redness, or peeling. Applying large amounts over extensive areas of skin, particularly under airtight (occlusive) dressings, may increase absorption and the likelihood of adverse effects. If this occurs, remove any occlusive dressing, gently wash the treated area with cool water, discontinue further applications until advised otherwise, and consult your doctor or pharmacist if you are unsure how to proceed. If the product is accidentally swallowed, contact a poison control centre or seek medical attention immediately.

Diet & Lifestyle Advise

  • Wear daily sun protection: UV radiation triggers melanin production and can quickly reverse the benefits of your treatment. Apply a broad-spectrum sunscreen with SPF 30 or higher every day, even when it is cloudy.
  • Cover up outdoors: Wear wide-brimmed hats, sunglasses, and seek shade during peak sunlight hours to shield treated areas from UV damage.
  • Keep skin hydrated: Use a gentle, fragrance-free moisturiser to support your skin barrier, especially if you experience mild dryness from the treatment.
  • Avoid picking or scratching: Do not pick at acne, scabs, or insect bites, as physical trauma can trigger post-inflammatory hyperpigmentation, creating new dark spots.
  • Do not scrub your face: Avoid using harsh physical exfoliants, scrubbing brushes, or rough washcloths on the treated skin, which can worsen irritation and inflammation.
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How Soon It Starts Working

The time required for Melgain Lotion 5 ml to start to work: The time required for Melgain Lotion 5 ml to show its action is unknown. The time for which the effects of Melgain Lotion 5 ml last: The duration of action for Melgain Lotion 5 ml is clinically unknown.

What if you forget to take Melgain Lotion 5 ml

If you forget to apply Melgain Lotion 5 ml, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and return to your regular routine. Do not apply extra product or double the amount to make up for a missed application.

Storage

•Store Melgain Lotion 5 ml at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the container tightly closed when not in use to prevent air and moisture from degrading the active ingredients.

Drug Warnings

  • Perform a patch test: Apply a small amount to a hidden area of skin, such as the inner forearm, and wait 24 hours before the first full application to check for allergic reactions.
  • Avoid contact with sensitive areas: Do not get this product in your eyes, nose, mouth, or on other mucous membranes. If accidental contact occurs, rinse thoroughly with plenty of water.
  • Inspect the product before use: Do not apply the gel or cream if you notice significant changes in its colour, consistency, or if the product has separated.
  • Do not apply to damaged skin: Avoid using this product on broken, sunburned, windswept, or open wounds, as it can cause severe irritation and increase absorption into the bloodstream.
  • Avoid occlusive dressings: Do not wrap, bandage, or cover the treated area with airtight dressings unless specifically instructed by your doctor.

verifiedApollotooltip

The following medicines and topical products may interact with Melgain Lotion 5 ml:

  • Topical retinoids and peeling agents: Combining Melgain Lotion 5 ml with other exfoliating treatments (like salicylic acid, glycolic acid, or tretinoin) may increase the risk of skin irritation, dryness, and peeling. Talk to your doctor before combining these products.
  • Alcohol-based skincare products: Astringents, toners, or aftershaves containing high amounts of alcohol may cause severe stinging and dryness when used alongside Melgain Lotion 5 ml.

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verifiedApollotooltip
  • No clinically significant food interactions are known with Melgain Lotion 5 ml when used as directed.

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS DERMATOLOGICALS]

FAQs

Melgain Lotion 5 ml belongs to the "depigmenting agents" class. It is primarily used in vitiligo treatment.
Melgain Lotion 5 ml promotes the formation of pigment-producing cells known as melanocytes. It also aids in the migration of melanocytes to the afflicted area, restoring skin tone.
Depending on the severity of your medical condition, your doctor may prescribe it to you for an extended time on a daily basis. However, please do not use it continuously without consulting a doctor.
Do not apply any other topical medications without a doctor's recommendation. If it requires the application of any other medication, please maintain at least 2 hours gap in-between them.
Melgain Lotion 5 ml is safe if used as prescribed. No severe or fatal side effects or contraindications have been reported so far. If any of the side effects persist or worsen, consult your doctor.
Vitiligo does not cause skin discomfort, such as dryness, but the patches can sometimes be itchy.
It may vary depending on your skin concerns and the treatment protocol your doctor recommends. It is important to follow the specific instructions provided with the product or your doctor's instructions. Consult a professional if you have any questions or concerns about its use.
Melgain Lotion 5 ml is a treatment for vitiligo, a skin condition characterized by white patches due to melanin deficiency. While Melgain Lotion 5 ml can help promote melanocyte proliferation and migration, leading to repigmentation in affected areas, it may not completely cure white patches in all cases. Results may vary depending on individual skin types, the severity of vitiligo, and consistent product use. Some users may experience significant repigmentation, while others may see partial or minimal improvement.
The safety and effectiveness of Melgain Lotion 5 ml in children have not been extensively studied. As a result, it is recommended to exercise caution and consult with a healthcare professional or paediatrician before using Melgain Lotion 5 ml in children.
Melgain Lotion 5 ml is only for external use. Take a small amount of Melgain Lotion 5 ml on the fingertip and apply it as a thin layer on the clean and dry affected area as prescribed by your doctor. Wash your hands before and after using Melgain Lotion 5 ml if your hands are not the affected area to prevent the spread of infection.
Melgain Lotion 5 ml is generally considered safe when used as directed. However, there may be potential side effects or interactions to be aware of. Common side effects may include mild skin irritation, redness, itching, or dryness. These effects are usually mild and temporary, but consult your healthcare professional if they persist or worsen. To ensure safe use, follow the instructions, do a patch test, and start with a small area. Consult your healthcare professional for personalized guidance if you experience any unusual symptoms or have concerns.
Yes, childhood vitiligo can go away on its own in some cases. According to the American Academy of Dermatology, approximately 10-20% of children with vitiligo experience spontaneous repigmentation, meaning their skin regains its natural pigment without treatment. Additionally, early treatment may also improve the chances of repigmentation. However, it's essential to note that vitiligo can be unpredictable, and the likelihood of it going away on its own or with treatment varies from child to child.
Vitiligo is a chronic skin disorder that causes pale white spots to appear on the skin. It is caused by a deficiency of melanin, which is the pigment in the skin. Vitiligo can affect any skin area, but it commonly happens on the face, neck, and hands, as well as in skin creases. Vitiligo typically begins as a pale patch of skin that gradually becomes completely white. A patch's centre may be white, with paler skin surrounding it. The severity of the condition varies from person to person. Some people develop a few small white patches, while others develop larger white patches that spread across large areas of their skin.
Melgain Lotion 5 ml promotes repigmentation and improves patient outcomes in vitiligo. But it does not cure permanently.
Melgain Lotion 5 ml represents a safe and effective therapeutic option for vitiligo treatment.
Melgain Lotion 5 ml is a possible therapy option for vitiligo! While it is not yet a proven cure, studies suggest it may aid in skin repigmentation and improve the appearance of vitiligo lesions. However, keep in mind that everyone's experience with vitiligo is unique, and what works best for one person may not work for another.
Melgain Lotion 5 ml contains "Decapeptide" as an active ingredient.
Common side effects of Melgain Lotion 5 ml may include skin irritation, dry skin, and a burning sensation. Most of the $ name's side effects do not necessitate medical treatment and gradually fade over time. However, please contact your doctor if the side effects persist or worsen.
The exact cause is unknown, but it's believed to be an autoimmune disorder, possibly triggered by genetic, environmental, or stress factors.
Melgain Lotion 5 ml is generally considered ideal for all skin types, but consulting a healthcare professional for personalized advice is essential.
Vitiligo itself is not painful, but some people may experience itching or discomfort due to skin dryness or other related conditions.
Melgain Lotion 5 ml may help promote skin repigmentation, but its effectiveness in preventing the spread of vitiligo is still being studied.
Yes, protecting your skin from the sun, maintaining a healthy diet, and managing stress may help manage vitiligo.
Hormonal fluctuations may potentially trigger vitiligo, but more research is needed to understand the relationship.
Melgain Lotion 5 ml may have the potential to treat skin depigmentation caused by other disorders, such as alopecia areata or skin trauma, but additional research is needed. Do not treat any condition on your own using Melgain Lotion 5 ml.
Follow the application frequency and dosage directions advised by your healthcare practitioner or on the product's label.
Consult a healthcare practitioner before using Melgain Lotion 5 ml in sensitive regions, as its safety and efficacy have yet to be completely demonstrated.
Yes, you can use makeup over this product. Allow the cream or gel to dry completely and absorb into your skin before applying moisturiser, sunscreen, and makeup. Talk to your doctor or pharmacist if you experience clumping or skin irritation.
Your doctor will determine the best schedule for you. It is commonly prescribed for once-daily use at night, or twice-daily use in the morning and evening. Always follow up with sunscreen during the day. Talk to your doctor to confirm your specific schedule.
Melgain Lotion 5 ml is generally considered a milder depigmenting ingredient than treatments such as hydroquinone and may be used as part of a broader skincare regimen. However, direct clinical studies comparing decapeptide with hydroquinone are limited, and effectiveness may vary depending on the specific formulation, concentration, and individual skin condition. Depending on your skin condition, your doctor may recommend using it alone or alongside other ingredients such as niacinamide or kojic acid as part of a personalised treatment plan.
Yes, it is formulated to be gentle on most skin types, including sensitive skin. However, individuals with extremely sensitive skin or active skin conditions should proceed with caution. Talk to your doctor to ensure it is suitable for your skin type.
There is limited clinical data on the use of topical Melgain Lotion 5 ml during pregnancy or breastfeeding. To ensure the safety of you and your baby, always talk to your doctor before starting this or any new skincare treatment.
Mild dryness or flaking can happen when starting this treatment. If peeling occurs, you can use a gentle, fragrance-free moisturiser. If the peeling becomes severe, painful, or red, stop using the product and talk to your doctor.
You should avoid applying this product to open, inflamed acne lesions, as it can cause stinging and irritation. It is best used on healed acne scars or post-inflammatory dark spots. Talk to your doctor for guidance on managing active acne.
Melgain Lotion 5 ml is designed to target areas of excess pigmentation, but some lightening of the surrounding normal skin may occur if it is applied beyond the affected area. Apply the product carefully and only as directed. If you notice unexpected or widespread skin lightening, stop using the product and consult your doctor.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

DEMPO TOWERS 5TH FLOOREDC PATTO PLAZA PANJIM GOA GA 403001 IN
Other Info - MEL0044

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