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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Metlin-NT 50 Tablet is used to treat Neuropathic pain. It contains Mecobalamin, Pregabalin, and Nortriptyline. Mecobalamin is a vitamin that aids in producing myelin, which protects nerve fibres and regenerates damaged nerve cells. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, it helps to treat neuropathic pain.

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Manufacturer/Marketer :

Alteus Biogenics Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Metlin-NT 50 Tablet

Metlin-NT 50 Tablet is a combination medicine indicated to manage neuropathic pain associated with diabetic peripheral neuropathy and postherpetic neuralgia. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, and evoked pain (pain caused by events usually not painful).

Metlin-NT 50 Tablet combines three drugs: Mecobalamin, Pregabalin, and Nortriptyline. Mecobalamin is a vitamin that aids in producing myelin, which protects nerve fibres and regenerates damaged nerve cells. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, Metlin-NT 50 Tablet helps to treat neuropathic pain.

Take Metlin-NT 50 Tablet as prescribed. Your doctor will decide the dose and duration based on your medical condition. In some cases, Metlin-NT 50 Tablet may cause dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of the lower legs and hands), weight gain, and dry mouth. These side effects do not necessitate medical attention and will subside gradually over time. However, you should consult your doctor if you are experiencing these side effects regularly.

Please do not take Metlin-NT 50 Tablet if you are allergic to any of its ingredients. Consult your doctor before taking Metlin-NT 50 Tablet if you are pregnant or breastfeeding. Metlin-NT 50 Tablet may cause drowsiness and dizziness, so drive only if alert. Metlin-NT 50 Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Metlin-NT 50 Tablet as it could increase dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to avoid side effects.

Uses of Metlin-NT 50 Tablet

Metlin-NT 50 Tablet is used in the treatment of Neuropathic pain. The detailed uses of Metlin-NT 50 Tablet are as follows:<br/>• Neuropathic pain relief: Metlin-NT 50 Tablet is used to treat neuropathic pain relief such as diabetic neuropathy, post-herpetic neuralgia, or sciatica.<br/>• Peripheral nerve disorders: Metlin-NT 50 Tablet helps in treating peripheral nerve disorders including numbness, tingling, or burning sensations.<br/>

Directions for Use

• Metlin-NT 50 Tablet can be taken with or without food as directed by your doctor.• It is advised to take Metlin-NT 50 Tablet once or twice daily; however, follow your doctor's advice regarding the dosage and duration.• Swallow the whole medicine with a glass of water.• Do not break, crush or chew Metlin-NT 50 Tablet .

Medicinal Benefits

Metlin-NT 50 Tablet is a combination of three drugs: Mecobalamin, Pregabalin, and Nortriptyline. Metlin-NT 50 Tablet is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Mecobalamin aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, Metlin-NT 50 Tablet helps to treat neuropathic pain.

How Metlin-NT 50 Tablet Works

Metlin-NT 50 Tablet combines three drugs: Mecobalamin, Pregabalin, and Nortriptyline. Mecobalamin is a vitamin that aids in producing myelin, which protects nerve fibres and regenerates damaged nerve cells. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, Metlin-NT 50 Tablet helps to treat neuropathic pain.

Storage

• Store in a cool and dry place away from sunlight.• Keep Metlin-NT 50 Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Metlin-NT 50 Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Metlin-NT 50 Tablet may include agitation, coma, confusion, irregular heartbeats, severe drowsiness, hallucinations, overactive reflexes, feeling hot or cold, stiff muscles, seizures, vision problems and vomiting. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

If you are allergic to any of the ingredients in Metlin-NT 50 Tablet , do not consume it. Please do not stop taking Metlin-NT 50 Tablet without consulting your doctor, as this may result in withdrawal symptoms. If you are pregnant or breastfeeding, do not take Metlin-NT 50 Tablet unless your doctor has prescribed it. Metlin-NT 50 Tablet may cause drowsiness and dizziness; therefore, drive only if alert. Metlin-NT 50 Tablet is not recommended for children as safety and effectiveness have not been established. Avoid drinking alcohol while taking Metlin-NT 50 Tablet as it may cause drowsiness and sleepiness. If you have suicidal thoughts, consult your doctor right away.

Drug-Drug Interactions

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NortriptylinePotassium citrate
Critical

Drug-Drug Interactions

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NortriptylinePotassium citrate
Critical
How does the drug interact with Metlin-NT 50 Tablet:
Coadministration of Metlin-NT 50 Tablet with Potassium citrate can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Metlin-NT 50 Tablet with Potassium citrate together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, abdominal pain, bloating, decreased hunger, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Metlin-NT 50 Tablet:
Co-administration of Metlin-NT 50 Tablet with Selegiline might raise serotonin hormone levels in the body (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Metlin-NT 50 Tablet with Selegiline together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metlin-NT 50 Tablet:
Coadministration of Metlin-NT 50 Tablet with Tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Metlin-NT 50 Tablet with Tranylcypromine together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Metlin-NT 50 Tablet:
Coadministration of Metlin-NT 50 Tablet with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Metlin-NT 50 Tablet with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, severe or prolonged diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metlin-NT 50 Tablet:
Coadministration of Metlin-NT 50 Tablet with Safinamide may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Metlin-NT 50 Tablet with Safinamide together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Metlin-NT 50 Tablet:
Coadministration of Metlin-NT 50 Tablet with Linezolid might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Metlin-NT 50 Tablet with Linezolid together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NortriptylineIsocarboxazid
Critical
How does the drug interact with Metlin-NT 50 Tablet:
Using Metlin-NT 50 Tablet together with Isocarboxazid can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Taking Isocarboxazid with Metlin-NT 50 Tablet is not recommended, please consult your doctor before taking it. However, if you experience increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea call a doctor. Do not discontinue any medications without consulting a doctor.
PregabalinHydromorphone
Severe
How does the drug interact with Metlin-NT 50 Tablet:
Using Metlin-NT 50 Tablet together with Hydromorphone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydromorphone and Metlin-NT 50 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinPethidine
Severe
How does the drug interact with Metlin-NT 50 Tablet:
Using Metlin-NT 50 Tablet together with Pethidine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pethidine and Metlin-NT 50 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinAlfentanil
Severe
How does the drug interact with Metlin-NT 50 Tablet:
Using Metlin-NT 50 Tablet together with Alfentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Metlin-NT 50 Tablet and Alfentanil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include vitamin B and D-rich foods in your diet.
  • Your diet should include Cayenne pepper because it can help with neuropathic pain.
  • Exercising regularly helps to improve overall health and combat pain.
  • Rest well and get plenty of rest.
  • Taking a warm bath can be very relaxing.
  • Avoid smoking and drinking alcohol.
  • Meditation and yoga can reduce stress, and pain sensitivity, and improve coping skills.
  • Acupuncture, by stimulating pressure points, can be beneficial.
  • Massages with essential oils can help increase circulation.

Habit Forming

No

Therapeutic Class

NEUTRACEUTICAL
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Metlin-NT 50 Tablet as it may increase drowsiness and sleepiness.

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Pregnancy

Caution

If you're pregnant, don't take Metlin-NT 50 Tablet unless your doctor tells you to. Please consult your doctor if you have any concerns about this; your doctor will only prescribe if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor as there is no substantial research yet on the use of Metlin-NT 50 Tablet in breastfeeding/nursing mothers.

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Driving

Caution

Metlin-NT 50 Tablet causes drowsiness, sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Inform your doctor before receiving the Metlin-NT 50 Tablet if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current liver conditions.

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Kidney

Caution

Inform your doctor before receiving the Metlin-NT 50 Tablet if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your current liver conditions.

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Children

Unsafe

Metlin-NT 50 Tablet should not be given to children as the safety and efficacy have not been established.

Have a query?

FAQs

Metlin-NT 50 Tablet is used to treat Neuropathic pain.

Metlin-NT 50 Tablet contains Mecobalamin, Pregabalin, and Nortriptyline. Mecobalamin aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Nortriptyline alters the way nerves receive pain signals, thereby decreasing pain. Together, Metlin-NT 50 Tablet helps to treat neuropathic pain.

Metlin-NT 50 Tablet contains pregabalin. It may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.

Dry mouth could be a side-effect of Metlin-NT 50 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Do not stop taking Metlin-NT 50 Tablet without consulting your doctor, as this could result in withdrawal symptoms. Continue taking Metlin-NT 50 Tablet for as long as prescribed to treat your condition effectively. If you experience any difficulty while taking Metlin-NT 50 Tablet , do not be afraid to speak with your doctor.

Metlin-NT 50 Tablet is used to treat diabetic neuropathy. Diabetic neuropathy is a condition that causes nerve damage due to high blood glucose levels. It primarily affects the nerves in the legs and feet.

Metlin-NT 50 Tablet may cause peripheral oedema. The swelling of the hands and lower legs are known as peripheral oedema. If you experience oedema, avoid sitting or standing for extended periods. Raise your legs by laying down and placing a pillow under them.

Metlin-NT 50 Tablet is a combination medicine that contains mecobalamin, pregabalin, and nortriptyline. It is effectively used in the treatment of neuropathic pain.

Metlin-NT 50 Tablet may cause sleepiness or drowsiness. To overcome sleepiness or drowsiness, try getting moving, taking a short walk, or stretching, cold shower, and some fresh air. Drink water or other non-caffeinated fluids to stay hydrated. However, consult your doctor if you're consistently struggling with sleepiness.

Taking Metlin-NT 50 Tablet can affect your sexual life. You might experience lower sex drive, erectile dysfunction, or problems with ejaculation or orgasm. If you notice any of these changes, it's important to tell your doctor. They can help you find solutions or adjust your medication to minimize these effects.

The common side effects of Metlin-NT 50 Tablet may include dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of the lower legs and hands), weight gain, and dry mouth. These side effects do not necessitate medical attention and will subside gradually over time. However, you should consult your doctor if you are experiencing these side effects regularly.

The time it takes for Metlin-NT 50 Tablet to take effect can vary from person to person. Some people may start feeling better within a couple of weeks, while others may need 4 to 6 weeks to experience the full benefits. The exact treatment duration will depend on your medical condition, and your doctor will provide personalized guidance on the recommended treatment course.

Focus on nutrient-dense foods, be mindful of your portion sizes, and avoid high-calorie snacks like crisps, cakes, biscuits, and sweets. Instead, opt for fresh fruits and vegetables, low-calorie foods, whole grains, and lean protein sources. Regular exercise will also help stabilize your weight and support overall health and well-being.

If you forget to take Metlin-NT 50 Tablet , take it as soon as you remember if it's within a few hours. If it's almost time for your next dose, skip the missed one and continue as usual. Don't take a double dose to make up for it. If you're unsure or frequently forget doses, consult your doctor or pharmacist for guidance. Taking medication at the same time every day can help make it a habit and reduce the likelihood of forgetting.

Do not take more Metlin-NT 50 Tablet than prescribed. Be aware of serious side effects like abnormal heartbeat, seizures, allergic reactions, and suicidal thoughts. If you experience any of these, tell your doctor right away and get medical help immediately to avoid serious problems.

Taking more than the recommended dose of Metlin-NT 50 Tablet won't improve its effectiveness and can be harmful. Stick to the recommended dosage to minimize risks and maximize benefits. If you have concerns, consult your doctor for personalized guidance.

While taking Metlin-NT 50 Tablet , be aware of potential interactions and risks. Avoid excessive alcohol consumption, driving, and operating heavy machinery until you know how the medication affects you. Also, consult your doctor before taking other medications, or supplements, or changing your diet and exercise routine. Limit grapefruit intake and exercise caution with opioid medications, as they may interact with Metlin-NT 50 Tablet . By following your doctor's guidance, you can minimize risks and ensure the medication works effectively for you.

Regular doctor's visits are important when receiving medical treatment. How often you visit will depend on your situation, but expect more frequent visits during the initial treatment phase to adjust plans and monitor side effects. Even during maintenance, regular check-ins will help track progress and address concerns. This helps ensure you receive the best care and stay on track with your treatment.

Metlin-NT 50 Tablet should be stored in a cool and dry place away from sunlight and keep it out of reach of children. When disposing, check the expiration date, remove the label, and throw it away in a plastic bag in the household trash. Do not flush it down the toilet or sink. Follow these steps to keep the medication safe and effective.

Country of origin

India

Manufacturer/Marketer address

Alteus Biogenics Pvt. Ltd., 14-B Dover Lane, Kolkata - 700029, Wb, India.
Other Info - MET2353

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