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compositionComposition:METRONIDAZOLE-2%W/W
prescription
Prescription Medicine
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Metrogyl Gel is an antimicrobial medication used in the treatment of rosacea. It helps to treat pimples, pustules (spots), and redness associated with this condition. This medicine inhibits the bacterial growth and thus alleviates rosacea lesions. Common side effects include dryness, redness, itching, irritation, burning, and stinging sensation.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

METRONIDAZOLE-2%W/W

Manufacturer/Marketer :

Lekar Pharma Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Metrogyl Gel

Metrogyl Gel is a prescription topical gel used to treat the inflammatory bumps, pimples, and redness caused by rosacea. This medicine targets skin irritation directly at the source to help manage sudden flare-ups and maintain a clearer complexion. It is formulated specifically for external use on the skin.

To achieve the best results, you must apply Metrogyl Gel consistently at the same times every day as directed by your doctor. While this topical treatment can be applied without regard to meals, you should always apply it to clean, completely dry skin. Adopting a gentle skincare routine and avoiding spicy foods, hot drinks, and extreme temperatures can significantly support your treatment outcomes.
Some people using Metrogyl Gel may experience mild skin reactions such as temporary dryness, itching, or redness. These local effects are usually mild, but you must contact your doctor immediately if you experience severe skin irritation, swelling, or signs of an allergic reaction.

Talk to your doctor or pharmacist before starting this treatment if you have a history of blood disorders or extreme skin sensitivity. Do not use this medicine if you have a known allergy to any of the ingredients in this topical formula.
Although very little of this medicine is absorbed into the blood, avoiding alcohol during treatment is recommended to prevent rare but uncomfortable reactions like facial flushing or nausea. If you are pregnant, breastfeeding, or planning a pregnancy, consult your doctor before starting Metrogyl Gel to ensure it is safe for you.

Uses of Metrogyl Gel

Your doctor may prescribe Metrogyl Gel to help manage the following conditions:

  • Rosacea: Metrogyl Gel reduces the redness, swelling, and inflammatory pimples (papules and pustules) associated with this chronic skin condition.
  • Inflammatory skin infections: Metrogyl Gel helps clear up specific bacterial skin infections by targeting the microbes causing the irritation and swelling.

Key Benefits

When used as directed as part of your treatment plan, Metrogyl Gel may provide the following benefits:

  • Helps reduce rosacea symptoms: Helps reduce inflammatory bumps, pimples, redness, and swelling associated with rosacea.
  • May improve skin comfort: As inflammation decreases, symptoms such as burning, stinging, and irritation may gradually improve.
  • Supports clearer-looking skin: Regular use may help reduce the number of inflammatory skin lesions and improve the overall appearance of your skin.
  • Helps reduce rosacea flare-ups: Continued treatment may help keep rosacea symptoms under better control and reduce flare-ups.
  • Supports healthy skin: By controlling inflammation, it helps protect the skin and supports its natural healing process.
Side effects of Metrogyl Gel 30 gm
  • Moisturize frequently with thick, broad-spectrum moisturizers containing sunscreen.
  • Use warm water for short baths, and gentle cleansers.
  • Pat dry and apply moisturizer immediately.
  • Use a humidifier to add moisture to the air, and choose breathable fabrics like cotton and silk.
  • Wash clothes with fragrance-free detergents to minimize irritation.
  • After taking a shower or bath, apply a moisturizer to damp skin.
  • Use petroleum jelly or other thick emollients.
  • Use a hypoallergenic, fragrance-free moisturizer 2 to 3 times a day or as frequently as required.
  • Exfoliate your skin gently using a pumice stone or slightly abrasive sponge.
  • Do not scrub your skin.
  • Avoid hot showers or baths. Instead take short, warm showers or baths.
  • Use mild soap or skin cleansers with added moisturizer.
  • Drink lots of water.
  • Use sunscreen and wear protective clothing while going out to protect yourself from sun damage.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Here are the steps to manage medication-triggered Burning Or Stinging:
  • If you experience burning or stinging sensations and suspect that they may be related to medication, consult a doctor or healthcare expert to determine the cause and best course of treatment.
  • Avoid harsh products, extreme temperatures, and other potential irritants that may exacerbate burning or stinging.
  • Your healthcare professional may recommend applying a soothing or protective agent, such as a cream, gel, or ointment, to help alleviate burning or stinging.
  • Follow your healthcare professional's advice on how to care for the affected area, as gentle cleaning and care instructions may vary depending on the location and severity of the burning or stinging.
  • Schedule follow-up appointments with your doctor to monitor your symptoms and adjust your treatment plan as needed. If the burning or irritation persists or worsens, seek medical attention.
  • Clean the affected area with soap and water.
  • Apply a cold compress on the affected area for relief.
  • Avoid scratching the affected area.
  • Inform your doctor about the reaction so they can adjust your treatment plan and suggest alternative medications.
  • Get immediate medical attention if symptoms persist or worsen.
  • Consult a healthcare professional to diagnose the skin infection and receive appropriate treatment.
  • Follow your doctor's instructions for treatments including creams, ointments, or antibiotics to stop the spread of germs.
  • Avoid scratching to help stop further infection and irritation.
  • Particularly after handling the affected region, wash your hands frequently.
  • To stop the spreading of infection, avoid sharing personal items including towels, clothes, and makeup.
  • Keep your skin moist to avoid dryness and irritations.
  • If your symptoms worsen or don't change, let your doctor know as they provide medical attention.
  • Tell your doctor about the excessive oiliness so they can adjust your medication or offer advice.
  • Your doctor may recommend alternative medications with fewer side effects on oil production.
  • Wash your skin twice a day with a gentle cleanser to remove excess oil and dirt.
  • Choose oil-free, non-comedogenic products to prevent clogged pores.
  • Use clay masks to absorb excess oil and cleanse the skin.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Apply a small amount of Metrogyl Gel as a thin layer on the clean and dry affected area.
  • Wash your hands before and after using Metrogyl Gel to prevent the spread of infection.

How Metrogyl Gel Works

Metrogyl Gel contains metronidazole. Metronidazole works primarily through its anti-inflammatory and antimicrobial actions. When you apply it to the affected areas, the active ingredient helps destroy harmful bacteria and microorganisms that can contribute to skin inflammation. Additionally, it acts as an antioxidant, reducing the release of reactive oxygen species that cause tissue damage, swelling, and redness in conditions like rosacea. This dual action helps calm irritated skin and prevents new bumps from forming.
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Alcohol

Caution

No reported interaction. But, it is best to avoid alcohol while using Metrogyl Gel.

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Pregnancy

Caution

There are no competent and well-controlled studies on pregnant women. Please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult the doctor. There are no appropriate and well-controlled studies on nursing mothers. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Safe if prescribed

Metrogyl Gel does not impact your ability to drive or operate machinery.

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Liver

Caution

Limited information is available; hence, if you have any concerns, discuss them with your doctor.

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Kidney

Caution

Limited information is available; hence, if you have any concerns, discuss them with your doctor.

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Children

Caution

Metrogyl Gel should not be used in children unless prescribed by a doctor.

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Heart

Caution

Please consult your doctor if you have any concerns regarding the use of Metrogyl Gel in patients with heart problems.

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Geriatrics

Consult your doctor

Limited information available about the use of Metrogyl Gel in geriatric patients. Please consult your physician.

What if I have taken an overdose of Metrogyl Gel

Since Metrogyl Gel is applied to the skin, an accidental overdose from normal topical use is highly unlikely. However, if the medication is accidentally swallowed, seek immediate medical attention.

Diet & Lifestyle Advise

  • Identify your triggers: Common triggers such as spicy foods, hot drinks, alcohol, emotional stress, and extreme temperatures may worsen rosacea. Try to identify and avoid your personal triggers.
  • Protect your skin from the sun: Apply a broad-spectrum sunscreen with SPF 30 or higher every day and wear a hat when outdoors, as sunlight can trigger flare-ups.
  • Use gentle skincare products: Choose fragrance-free cleansers and moisturisers designed for sensitive skin to help reduce irritation.
  • Avoid skin irritants: Do not use harsh scrubs, alcohol-based products, or other skincare products that may dry or irritate your skin.
  • Care for your skin gently: Wash your face with lukewarm water and pat it dry with a soft towel instead of rubbing.

Health Queries

I am treating a bacterial vaginal infection (BV) with Metrogyl Gel 2% and oral antibiotics, but I am still experiencing vaginal itching, a rash, and swelling; is it normal to see a yellowish discharge after applying the gel on my first day, should I stop using it, and do I need to reapply the gel every time I use the bathroom to pee?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

It is completely normal to see a yellowish discharge on your first day of Metrogyl Gel 2% (metronidazole), as the gel melts and clears the infection. Also, you do not need to reapply the gel after urinating, as urine does not wash it out of the vagina. However, your symptoms of itching, rash, and swelling are not typical and could suggest a yeast infection triggered by the antibiotics, or a mild sensitivity. Please consult your doctor before stopping the medication so they can safely evaluate these symptoms and help you find relief.

Why does my face become very red every time I stop using METROGYL gel, and what can I do to treat this since my skin was previously damaged by using HHFUDIC cream for two years?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

Your skin was likely sensitized by the long-term use of HHFUDIC cream, which contains a strong steroid. This can cause steroid-induced rosacea. When you stop METROGYL gel (metronidazole), which controls the inflammation, your blood vessels dilate again, causing rebound redness. To help your skin heal, please avoid harsh soaps and use a gentle, fragrance-free moisturizer to repair your skin barrier. It is very important to consult a dermatologist. They can guide you on a safe, gradual treatment plan to calm your skin without causing these flare-ups.

Can I apply Metronidazole gel on my face?

Veda Maddala

Veda Maddala

M Pharmacy

Yes, you can apply Metronidazole gel on your face, but only if it has been prescribed by your doctor. It is a common topical treatment for facial skin conditions like rosacea, which helps reduce redness, inflammation, and pimples. To use it, first wash your face with a gentle cleanser and pat it completely dry. Apply a thin layer to the affected areas as directed, usually once or twice a day. Avoid getting the gel in your eyes, nose, or mouth, as it can cause burning and irritation. If contact occurs, rinse well with water. Always follow your doctor's specific application instructions.

Can I use Metrogyl gel 2% for acne? If yes, how should I use it?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

Yes, Metrogyl gel (Metronidazole) can be used if the acne (pimples) is related to rosacea, but it is not meant for common acne. Apply a thin layer of the gel to the clean and dry affected area once or twice daily, as advised by your doctor. Wash your hands before and after use, and avoid contact with your eyes and mouth.

Can Metrogyl Gel be used for a varicose vein ulcer infection?

Bayyarapu Mahesh Kumar

Bayyarapu Mahesh Kumar

M Pharmacy

Metrogyl Gel can sometimes be used for wound infections, but varicose vein ulcers usually need more than just an ointment. They often require proper wound assessment, special dressings, compression therapy to improve circulation, and antibiotics if infection is confirmed. Using Metrogyl Gel on your own is not recommended. It is best to have a doctor or wound care specialist examine the ulcer, confirm whether infection is present, and guide appropriate treatment to ensure safe healing.
health query

Have a query?

How Soon It Starts Working

The time required for Metrogyl Gel to start to work: Metrogyl Gel ideally shows its action within few hours after administration. The time for which the effects of Metrogyl Gel last: The duration of action for Metrogyl Gel is clinically unknown.

What if you forget to take Metrogyl Gel

If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and resume your regular routine. Do not apply a double amount to make up for a missed one.

Storage

•Store Metrogyl Gel at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F).•Keep the container tightly closed when not in use to prevent the product from drying out.

Drug Warnings

  • For external use only: Avoid getting this medicine in your eyes, nose, mouth, or on broken skin. If accidental contact occurs, rinse thoroughly with water.
  • Apply to clean, dry skin: Use a thin layer only on the affected areas as directed by your doctor. Wash your hands after applying the medicine unless your hands are being treated.
  • Allow the medicine to dry: Let the medicine dry completely before applying moisturisers, sunscreen, cosmetics, or other skincare products.
  • Do not use more than prescribed: Applying larger amounts or using it more often will not improve results and may increase skin irritation.
  • Consult your doctor right away: Seek medical advice if your skin irritation becomes severe, your rosacea worsens, or your symptoms do not improve after several weeks of regular treatment.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (such as warfarin): Although very little of this medicine is absorbed through the skin, it may occasionally increase the risk of bruising or bleeding. Tell your doctor if you are taking blood thinners.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Metrogyl Gel when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS - TOPICAL]

FAQs

Metrogyl Gel belongs to a group of medicines known as nitroimidazole antimicrobials used to treat rosacea.
Metrogyl Gel works by stopping the growth of bacteria. Thereby treats rosacea.
While using Metrogyl Gel, avoid direct sunlight, sun lamps, light therapy, tanning beds, strong massage, physical irritants, and extremely cold weather.
Metrogyl Gel should not be used on unhealed wounds, open wounds or mucous membranes (eyes, nose, mouth, and genital areas).
Consult your doctor before using other skin creams containing Metronidazole. If your doctor suggests any other skin creams or ointments in addition to Metrogyl Gel, you should maintain a time gap of at least thirty minutes between the two topical medicines.
Rosacea may respond slowly to antibiotics such as Metrogyl Gel. It is critical that you continue to use Metrogyl Gel for as long as it is advised by your doctor.
Yes, you can apply makeup after using this medicine. However, you should wait at least 5 to 10 minutes after applying Metrogyl Gel to let it fully absorb into your skin first. Use gentle, non-comedogenic cosmetics to avoid clogging your pores. Talk to your doctor if you experience increased irritation.
While only small amounts of this topical medication are absorbed into the body, you should use it during pregnancy or breastfeeding only if clearly needed. Always discuss the potential risks and benefits with your healthcare provider. Talk to your doctor to determine what is safest for you.
Although the amount of medicine absorbed through the skin is very low, it is safest to avoid alcohol during your treatment. Some people may experience a disulfiram-like reaction, which includes headaches, nausea, and flushing. Talk to your doctor or pharmacist if you have questions about alcohol use.
No, Metrogyl Gel is primarily prescribed for rosacea and specific inflammatory skin conditions, not typical hormonal acne. Using it for untreated acne may not yield the desired results. Talk to your doctor for an appropriate acne treatment plan.
If the medication accidentally gets into your eyes, rinse them immediately and thoroughly with plenty of cool, clean water. If you experience persistent burning, pain, or vision changes after rinsing, talk to your doctor right away.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.925 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.922 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. U.S. Food and Drug Administration (FDA). 021789Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  4. National Health Service (NHS). About Metronidazole - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  5. Drugs.com Clinical Review Team. Metronidazole Topical,Metrogel Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  6. Metronidazole Metronidazole. 2013. [Accessed on 29 Mar. 2019]Check here
  7. Metronidazole 500 mg Film-Coated Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 16 September 2025]Check here

Country of origin

India

Manufacturer/Marketer address

Cnergy IT Park, 3rd floor Appa Saheb Marathe Marg, Prabhadevi, Mumbai 400025
Other Info - MET1335

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