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compositionComposition:DESMOPRESSIN-0.1MG
prescriptionPrescription Medicine
Minirin Nasal Spray 2.5 ml

Minirin Nasal Spray is used to treat central cranial diabetes insipidus and temporary polyuria (extreme urination) or polydipsia (extreme thirst) after head trauma. It mimics the natural hormone vasopressin and works by reabsorbing water from the kidneys, which controls excessive thirst and urination. Some common side effects include weakness, headache, nasal congestion/stuffy nose, rhinitis/runny nose, nosebleeds, nausea, upset stomach, abdominal pain, and flushing.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DESMOPRESSIN-0.1MG

Manufacturer/Marketer :

Ferring Pharmaceuticals Pvt Ltd

Consume Type :

Nasal

Expires on or after :

Jan-27

Return Policy :

Not Returnable

Minirin Nasal Spray is primarily used as replacement therapy in central cranial diabetes insipidus. It is also used to manage temporary polyuria (extreme urination) or polydipsia (extreme thirst) after head trauma or surgery in the pituitary gland.

Minirin Nasal Spray contains Desmopressin, which mimics the natural hormone vasopressin and works by reabsorbing water from the kidneys, which controls excessive thirst and urination. Thus, it prevents dehydration. 

Common side effects of Minirin Nasal Spray include conjunctivitis/red eyes, weakness, headache, nasal congestion/stuffy nose, rhinitis/runny nose, nosebleeds, nausea, and upset stomach. If the side effects persist or worsen, seek a doctor's advice.

Let your doctor know if you have severe kidney disease, hyponatremia (low sodium levels), excessive fluid intake, high blood pressure, heart problems/failure, swelling or scarring of the nasal lining, or illnesses that cause fluid/mineral imbalance.

Uses of Minirin Nasal Spray

Minirin Nasal Spray is used in the treatment of central cranial diabetes insipidus, polyuria, and polydipsia. The detailed uses of Minirin Nasal Spray are as follows:

  • Treat central diabetes insipidus: Minirin Nasal Spray replaces the natural antidiuretic hormone (vasopressin) to reduce excessive urination and thirst caused by a deficiency in this hormone.
  • Manage nocturnal polyuria (frequent nighttime urination): Minirin Nasal Spray helps adults who wake up multiple times at night to urinate by decreasing urine production during sleep.

Key Benefits

  • Minirin Nasal Spray is used to control excessive thirst and urination caused by an imbalance in the body’s water regulation.
  • It contains Desmopressin, a synthetic analogue of vasopressin, which acts as an antidiuretic hormone to maintain the body’s fluid balance.
  • Minirin Nasal Spray works by reducing the amount of water excreted in the urine, helping the body retain necessary fluids and prevent dehydration.
  • It helps restore normal urine output and regulate fluid levels, improving comfort and hydration.
  • By mimicking the natural hormone vasopressin, it provides effective control over frequent urination and excessive thirst.
Side effects of Minirin Nasal Spray 2.5 ml
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Rest well; get enough sleep.
  • Wear comfortable layers of clothes and get to a warm place.
  • Drink warm fluids like coffee, tea or hot chocolate.
  • Warm up using a blanket or heating pad.
  • Try eating smaller meals (4-5 times) instead of large ones to make it easier on your stomach.
  • Avoid foods that are spicy, fatty, or high in insoluble fibre.
  • Consuming soluble fibre (such as psyllium) can help with constipation, and probiotics may reduce bloating and discomfort.
  • Stay away from carbonated drinks, alcohol, caffeine, and smoking, as they can upset your stomach.
  • Reducing stress, losing weight, and exercising regularly for 20-30 minutes can help improve digestion and reduce stomach issues.
  • Poor sleep can worsen stomach problems, so focus on good sleep habits or use tools like Sleepio to improve your sleep.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

  • It is advised to use Minirin Nasal Spray once daily; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Read the instructions on the label before using. Prime the nozzle, if required. Blow your nose. Tilt your head back and insert the tip of the nozzle into your nostril. Spray into the nostril while breathing in slightly. When pressing down the pump, apply even pressure and press down quickly to produce a consistent spray. Repeat the same process for another nostril if required.
  • Wipe off the tip with a clean tissue and replace the cap.
Minirin Nasal Spray contains Desmopressin, which mimics the natural hormone vasopressin and works by reabsorbing water from the kidneys, which controls excessive thirst and urination.
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Alcohol

Caution

Alcohol consumption may interfere with the working of Minirin Nasal Spray ; hence it is advised to limit or avoid its intake.

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Pregnancy

Caution

Minirin Nasal Spray should be used in pregnancy only when recommended by a doctor. Please consult your doctor before starting Minirin Nasal Spray if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Minirin Nasal Spray is excreted into the breast milk when used by a breastfeeding mother. Please seek medical advice before you start Minirin Nasal Spray if you are nursing.

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Driving

Safe if prescribed

Minirin Nasal Spray usually does not interfere with your driving ability. Do not drive or operate machinery if you experience unmanageable side effects with Minirin Nasal Spray .

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Liver

Caution

Please let your doctor know if you have any history of liver diseases or hepatic impairment when you are prescribed Minirin Nasal Spray .

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Kidney

Caution

Minirin Nasal Spray is contraindicated in patients with moderate to severe renal impairment. Please let your doctor know if you have any history of kidney diseases when prescribed Minirin Nasal Spray .

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Children

Caution

Minirin Nasal Spray should be used in children only when prescribed by the doctor.

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Heart

Caution

Minirin Nasal Spray should be used with caution in patients with heart problems. Therefore, please consult your doctor before using Minirin Nasal Spray .

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Geriatrics

Caution

Minirin Nasal Spray should be used with caution in elderly patients due to an increased risk of side effects. It is important to consult a healthcare professional before use.

Avoid taking more than the prescribed dose of Minirin Nasal Spray as it can cause serious side effects. Overdose of Minirin Nasal Spray includes hyponatremia (low levels of sodium in the blood). Seek immediate medical attention if you observe any of these side effects.

Diet & Lifestyle Advise

  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Reduce the amount of salt and protein in your diet, which will help your kidneys produce less urine.
  • Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime since it can lead to increased urination.
  • Avoid activities that cause dehydration, such as excessive physical exercise or spending time in the heat.
  • Optimal water intake is recommended to prevent dehydration due to excessive urination.

Have a query?

Drug Warnings

  • Before starting Minirin Nasal Spray , let your doctor know if you have any history of allergic reactions to antidiuretic hormones, severe kidney disease, hyponatremia (low sodium levels in your body), excessive fluid intake, high blood pressure, heart failure, illnesses that cause fluid/mineral imbalance (cystic fibrosis), or fluid retention.
  • Please consult your doctor before starting Minirin Nasal Spray if you are pregnant, planning to conceive or are a breastfeeding mother.
  • Alcohol consumption may interfere with the working of Minirin Nasal Spray ; hence, it is advised to limit or avoid its intake.
  • Minirin Nasal Spray should be used in children only when prescribed by the doctor.

Drug-Drug Interactions

verifiedApollotooltip
DesmopressinBetamethasone
Critical
DesmopressinFluticasone furoate
Critical

Drug-Drug Interactions

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DesmopressinBetamethasone
Critical
How does the drug interact with Minirin Nasal Spray 2.5 ml:
Co-administration of Minirin Nasal Spray 2.5 ml with Betamethasone can increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Co-administration of Betamethasone and Minirin Nasal Spray 2.5 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, and/or sudden weight gain, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DesmopressinFluticasone furoate
Critical
How does the drug interact with Minirin Nasal Spray 2.5 ml:
Co-administration of Minirin Nasal Spray 2.5 ml together with fluticasone may increase the risk of hyponatremia, a condition associated with low levels of salt in the blood.

How to manage the interaction:
If you have to use Minirin Nasal Spray 2.5 ml and Fluticasone together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
DesmopressinTriamcinolone
Critical
How does the drug interact with Minirin Nasal Spray 2.5 ml:
Co-administration of Minirin Nasal Spray 2.5 ml together with triamcinolone may increase the risk of hyponatremia (a condition associated with low levels of salt in the blood).

How to manage the interaction:
Taking Triamcinolone with Minirin Nasal Spray 2.5 ml is not recommended, but it should be taken if advised by a doctor. However, if you experience nausea, vomiting, headache, tiredness, irritability, difficulty concentrating, confusion, muscle spasm, weakness, , decreased urination and loss of appetite(less desire to eat), contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DesmopressinDexamethasone
Critical
How does the drug interact with Minirin Nasal Spray 2.5 ml:
Co-administration of Minirin Nasal Spray 2.5 ml with Dexamethasone may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Co-administration of Dexamethasone and Minirin Nasal Spray 2.5 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DesmopressinCortisone
Critical
How does the drug interact with Minirin Nasal Spray 2.5 ml:
Co-administration of Cortisone and Minirin Nasal Spray 2.5 ml may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Minirin Nasal Spray 2.5 ml and Cortisone together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
DesmopressinCiclesonide
Critical
How does the drug interact with Minirin Nasal Spray 2.5 ml:
Co-administration of Bumetanide and Minirin Nasal Spray 2.5 ml may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Minirin Nasal Spray 2.5 ml and Ciclesonide together, a doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
DesmopressinFluticasone Propionate
Critical
How does the drug interact with Minirin Nasal Spray 2.5 ml:
Co-administration of Minirin Nasal Spray 2.5 ml together with fluticasone may increase the risk of hyponatremia, a condition associated with low levels of salt in the blood.

How to manage the interaction:
Coadministration of Minirin Nasal Spray 2.5 ml and Fluticasone Propionate is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, headache, lethargy, irritability, difficulty concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination and sudden weight gain contact doctor immediately. Do not discontinue any medications without consulting a doctor.
DesmopressinBumetanide
Critical
How does the drug interact with Minirin Nasal Spray 2.5 ml:
Co-administration of Bumetanide and Minirin Nasal Spray 2.5 ml may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Minirin Nasal Spray 2.5 ml and Bumetanide together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
DesmopressinBeclometasone
Critical
How does the drug interact with Minirin Nasal Spray 2.5 ml:
Co-administration of Minirin Nasal Spray 2.5 ml together with Beclomethasone may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Minirin Nasal Spray 2.5 ml and Beclomethasone together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
DesmopressinDeflazacort
Critical
How does the drug interact with Minirin Nasal Spray 2.5 ml:
Co-administration of Deflazacort and Minirin Nasal Spray 2.5 ml may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although co- administration of Daflazacort with Desmopression can possibly lead to an interaction, it can be taken in case a doctor advices you. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty in concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, or sudden weight gain. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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No
[HORMONES]

FAQs

Minirin Nasal Spray is an antidiuretic medicine used as replacement therapy in central cranial diabetes insipidus. It is also used to manage temporary polyuria (extreme urination) or polydipsia (extreme thirst) after head trauma.

Minirin Nasal Spray contains Desmopressin, a human-made form of vasopressin (antidiuretic hormone). When your body cannot produce enough vasopressin, Minirin Nasal Spray is used to replace it. It helps treat cranial diabetes insipidus, polyuria, and polydipsia.

Do not use Minirin Nasal Spray if you have polyuria that has not been diagnosed as diabetes insipidus. It is advised to use the Minirin Nasal Spray only when the doctor has suggested it for you, depending on your medical condition.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule.

Optimal intake of fluids is recommended to prevent dehydration. However, avoid excess intake of water and other liquids like coffee, tea, cola, and energy drinks during the treatment. Excessive fluid intake while using Minirin Nasal Spray may lead to a build-up of water, which dilutes the salt in the body, leading to serious problems.

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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K-28/1, ADDITIONAL MIDC , ANAND NAGAR , AMBERNATH - 421506 , INDIA
Other Info - MIN0009

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