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compositionComposition:MUPIROCIN-2%W/W
prescription
Prescription Medicine
info
Mupi Ointment 5 gm
Mupi Ointment 5 gm
Mupi Ointment 5 gm

Mupirocin ointment is an antibiotic used to treat certain bacterial skin infections. It is used for conditions such as impetigo (a contagious skin infection that causes sores or blisters), folliculitis (infected hair follicles that appear as small pus-filled pimples), and furunculosis (boils). It can be used in adults, adolescents, children, and infants aged 4 weeks and older. It works by killing bacteria that commonly cause skin infections, including Staphylococcus aureus (including some resistant types such as MRSA), other staphylococci, streptococci, and certain other bacteria. Most people tolerate it well, but possible side effects may include mild burning or stinging at the application site, redness, itching, skin soreness, or, rarely, an allergic rash. If severe irritation or signs of an allergic reaction occur, stop using the ointment and consult your healthcare provider.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

MUPIROCIN-2%W/W

Manufacturer/Marketer :

Hegde & Hegde Pharmaceutica Llp

Consume Type :

Topical

Expires on or after :

Dec-26

Return Policy :

Not Returnable

About Mupi Ointment 5 gm

Mupi Ointment 5 gm is a topical antibiotic medicine used to treat certain bacterial skin infections. It may also be available as a nasal ointment for specific uses such as bacterial decolonisation under medical guidance. t is specifically used to target and eliminate bacteria that cause skin conditions like impetigo, folliculitis, and infected cuts or wounds. Clearing the bacteria, it helps your skin heal and prevents the infection from spreading.

To get the best results, you must apply Mupi Ointment 5 gm consistently and exactly as directed by your healthcare provider, usually two to three times daily. Always apply it to clean, dry skin after washing your hands. Maintaining good personal hygiene, keeping the area clean, and avoiding scratching the lesions are simple lifestyle habits that can significantly speed up your recovery.

Mupirocin is available as a 2% cream and a 2% ointment. Your doctor may choose one formulation based on the type and location of the infection. Ointments are often preferred for dry or crusted lesions, while creams may be suitable for certain moist skin infections. Use only the formulation prescribed for you.

While using this medicine, some people may experience mild local skin reactions like temporary burning or itching. These are usually harmless, but you should consult your doctor right away if you experience severe skin irritation, blistering, or signs of a serious allergic reaction.

Talk to your doctor before starting this medicine if you have any pre-existing health conditions, especially kidney problems. Do not use this medicine if you have a known allergy to any of its ingredients. It is also important to avoid using it on large, open wounds or deeply broken skin without first consulting a professional.

Avoid using other skin products on the same area at the same time, as they can interfere with how this medicine works. If you are pregnant, breastfeeding, or treating an elderly individual, consult your doctor or pharmacist first to ensure safe use.

Uses of Mupi Ointment 5 gm

Your doctor may prescribe Mupi Ointment 5 gm to treat several conditions, including:

  • Impetigo: Mupi Ointment 5 gm treats this highly contagious bacterial skin infection, which often causes red sores on the face, by stopping the growth of the bacteria responsible.
  • Infected skin wounds: It helps clear bacterial infections that develop in minor skin breaks, such as small cuts, abrasions, or stitched wounds.
  • Folliculitis: It treats bacterial infections of the hair follicles, reducing redness, swelling, and pus-filled bumps.
  • Nasal decolonisation (specific mupirocin nasal ointment): Mupirocin may also be prescribed inside the nose to reduce colonisation with certain bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), particularly before some surgeries or in healthcare settings when recommended by a doctor. Nasal use is different from regular skin application.

Key Benefits

When taken as prescribed, Mupi Ointment 5 gm offers several important benefits, including:

  • Mupi Ointment 5 gm provides targeted relief directly at the site of infection. Because it is applied directly to the skin, very little of the medicine enters your bloodstream, which helps minimize the risk of internal side effects.
  • By stopping bacterial growth, this medicine relieves localized symptoms like pain, redness, itching, and swelling. It promotes faster healing of skin sores and lesions, helping your skin return to its healthy state. Additionally, clearing the bacteria prevents the infection from spreading to other areas of your body or to other people.
Side effects of Mupi Ointment 5 gm
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Managing Medication-Related Skin Allergies: A Step-by-Step Guide
  • If you experience signs of skin allergies such as redness, itching, or irritation after taking medication, contact your doctor right away.
  • To alleviate skin allergy symptoms, your doctor may change your medication regimen or offer tailored medication management advice.
  • Your doctor may recommend or prescribe drugs to relieve discomfort.
  • Cool compresses or calamine lotion can help relieve redness and itching on the afflicted skin area.
  • Staying hydrated by consuming plenty of water can help relieve discomfort.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Change positions or take a break from activity to relieve symptoms, as stinging can disturb your regular patterns.
  • Avoid postures that put much pressure on the body area where stinging is felt.
  • If you have a vitamin deficiency, take supplements or change your diet.
  • Exercise regularly to improve inner strength.
  • Follow your doctor's instructions to prevent stinging.
  • Massage the affected area gently to get temporary relief.
  • Burning sensation is an abnormal side effect that needs medical attention. To relieve the burning feeling, your doctor may prescribe painkillers or antidepressants.
  • Focused exercises can improve strength and reduce burning by soothing muscles.
  • Change in lifestyle and improving nutrition can reduce the causes of burning sensation and provide relief.
  • Your doctor may suggest nerve block injections as it is related to sensation in the skin.
  • Burning feeling in a specific area would need mild electrical currents to reduce pain that targets the nerve affected. This practice must be done only if your doctor mentions it.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Apply moisturizer immediately after showering or bathing.
  • Use a moisturizer containing lanolin, petroleum jelly, glycerine, hyaluronic acid or jojoba oil.
  • Do not use hot water for bathing. Instead use warm water and limit showers and bath to 5 to 10 minutes.
  • Apply a sunscreen with SPF-30 or higher.
  • Avoid harsh soaps, detergents and perfumes.
  • Do not scratch or rub the skin.
  • Drink adequate water to prevent dehydration.
  • Wear pants, full sleeves and a wide-brimmed hat while going out in the sun.

Directions for Use

Follow these steps to apply Mupi Ointment 5 gm safely and effectively:

  • Wash your hands thoroughly with soap and water before applying the medicine.
  • Clean and dry the affected skin area gently.
  • Apply a small amount of the prescribed mupirocin cream or ointment as a thin layer over the affected area. Do not switch between formulations unless advised by your doctor
  • You may cover the treated area with a sterile gauze bandage if your doctor advises you to do so.
  • Wash your hands again immediately after applying the medicine to prevent spreading the infection to other skin areas or your eyes.

Completing the prescribed course helps ensure that the infection is fully treated and reduces the chance of bacteria surviving and developing resistance to mupirocin. Do not stop treatment early or use leftover medicine for future infections unless advised by your doctor. Always follow your doctor's exact instructions regarding how often and how long to use this medicine. Do not stop using it early, even if your skin looks better, to prevent the infection from returning.

How Mupi Ointment 5 gm Works

Mupi Ointment 5 gm is an antibacterial medication designed to fight specific types of bacteria on your skin. It works by blocking a key enzyme that bacteria need to build their proteins. Without these proteins, the bacteria cannot grow, multiply, or repair themselves. As a result of this action, the bacteria eventually die off, and your body's natural immune system can easily clear away the remaining infection. Since it targets bacterial protein synthesis in a highly specific way, it is highly effective against common skin-infecting bacteria while sparing your body's healthy cells.
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Alcohol

Safe if prescribed

No reported interaction with Mupi Ointment 5 gm. But, It is best to avoid alcohol while taking medication.

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Pregnancy

Safe if prescribed

If you are pregnant, consult your healthcare provider before using Mupi Ointment 5 gm. Limited clinical data are available on its use during pregnancy, and your doctor can advise on potential risks and benefits.

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Breast Feeding

Safe if prescribed

It is not known whether Mupi Ointment 5 gm passes into breast milk. Before using this medication, inform your doctor if you are breastfeeding. If you are applying Mupi Ointment 5 gm to the breast or nipple, make sure to thoroughly wash the area before nursing your child.

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Driving

Safe if prescribed

Mupi Ointment 5 gm has no or negligible influence on the ability to drive or use machines.

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Liver

Safe if prescribed

Patients with liver impairment should consult their healthcare provider before using Mupi Ointment 5 gm, as clinical data on its use in such conditions is limited. Your doctor can provide guidance on appropriate use and monitoring.

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Kidney

Safe if prescribed

Patients with kidney impairment should consult their healthcare provider before using Mupi Ointment 5 gm, as clinical data on its use in such conditions is limited. Your doctor can provide guidance on appropriate use and monitoring.

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Children

Safe if prescribed

Mupi Ointment 5 gm can be used safely in children if prescribed by a doctor. The dose should be tailored based on the child’s age, weight, and medical condition. However, it should not be used in babies under 4 weeks of age.

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Heart

Consult your doctor

Patients with pre-existing heart problems should consult their healthcare provider before using Mupi Ointment 5 gm, as clinical data on its use in such conditions is limited. Your doctor can provide guidance on appropriate use and monitoring.

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Geriatrics

Consult your doctor

Limited information is available for use in erderly patients. Please consult your doctor.

What if I have taken an overdose of Mupi Ointment 5 gm

Do not apply Mupi Ointment 5 gm in large amounts or use it for a long time than recommended, as it does not give quick or better results but increases the risk of side effects.

Diet & Lifestyle Advise

  • Keep the infected skin clean and dry to prevent bacteria from multiplying.
  • Avoid picking, scratching, or squeezing the skin sores, as this can worsen the infection and cause scarring.
  • Wash your hands frequently with soap and water, especially after touching the affected area.
  • Do not share personal items such as towels, washcloths, clothing, or bedsheets with others to avoid spreading the infection.
  • Wear loose-fitting clothing over the treated area to prevent friction and irritation.

Health Queries

What safe medications or treatments can be used to manage severe skin problems in a kidney transplant patient?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Managing skin issues after a kidney transplant requires close coordination between your dermatologist and transplant team, as some treatments can interact with your anti-rejection medications. For dry or inflamed skin, thick, fragrance-free moisturizers and mild topical steroids (like hydrocortisone) are generally safe. Localized infections can be treated with topical antibiotics (like mupirocin) or topical antifungals (like clotrimazole). Crucially, always wear broad-spectrum zinc oxide sunscreen to protect your sensitive skin. Avoid starting any oral medications without consulting your doctor, as they can affect your kidney function. Your transplant team will safely tailor a treatment plan just for you.

What safe medications or treatments can be used to manage severe skin problems in a kidney transplant patient?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Managing skin issues after a kidney transplant requires close coordination between your dermatologist and transplant team, as some treatments can interact with your anti-rejection medications. For dry or inflamed skin, thick, fragrance-free moisturizers and mild topical steroids (like hydrocortisone) are generally safe. Localized infections can be treated with topical antibiotics (like mupirocin) or topical antifungals (like clotrimazole). Crucially, always wear broad-spectrum zinc oxide sunscreen to protect your sensitive skin. Avoid starting any oral medications without consulting your doctor, as they can affect your kidney function. Your transplant team will safely tailor a treatment plan just for you.

There seems to be a bacterial infection on my hand, causing redness and discomfort. How can I treat this properly?

Veda Maddala

Veda Maddala

M Pharmacy

Redness and discomfort on the hand can happen due to a bacterial skin infection, but sometimes it may also be irritation, allergy, insect bite reaction, or even a fungal issue that looks similar in the early stage. In bacterial infections, the area may feel warm, tender, swollen, and sometimes slowly expand if not treated properly. Keep the area clean with mild soap and water, and avoid scratching or squeezing it, as this can spread the infection deeper. Try to keep the hand dry and avoid using harsh chemicals or repeated antiseptic application unless advised. Covering the area lightly can help prevent further irritation if it is getting rubbed frequently. A doctor may need to examine the skin to confirm the cause and decide the right treatment, which could include topical or oral medicines depending on severity. Avoid starting random creams on your own, as incorrect use can delay healing. Please seek medical care urgently if the redness is spreading quickly, there is pus, severe pain, fever, red streaks on the arm, or if movement of the hand becomes difficult.

Have a query?

How Soon It Starts Working

  • The time required for Mupi Ointment 5 gm to start to work: The time required for Mupi Ointment 5 gm to show its action is unknown.
  • The time for which the effects of Mupi Ointment 5 gm last: The duration of action for Mupi Ointment 5 gm is unknown.

What if you forget to take Mupi Ointment 5 gm

Apply the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and follow your regular schedule. Do not apply Mupi Ointment 5 gm more frequently to make up for the missed dose.

Storage

• Store Mupi Ointment 5 gm at room temperature, ideally between 20°C and 25°C. Do not freeze the medicine, and keep the tube tightly closed when not in use.

Drug Warnings

  • This medicine is for external skin use only. Never apply it to your eyes, nose, mouth, or inside the vagina.
  • Complete the full course prescribed by your doctor, even if your skin improves earlier. Stopping treatment too soon may allow some bacteria to survive, increasing the risk of treatment failure and antibiotic resistance.
  • Do not mix or apply other topical skin creams, ointments, or lotions to the same area at the same time unless directed by your doctor.
  • Inspect the tube before use and do not use it if the seal is broken or if the product looks damaged.

If your skin condition does not improve within 3 to 5 days of starting treatment, contact your healthcare provider.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Inform your doctor if you are taking any of the following medicines, as they may interact.
  • Other topical medications: Avoid applying other creams, ointments, or lotions to the same skin area simultaneously. Doing so can dilute the Mupi Ointment 5 gm or prevent your skin from absorbing it properly.

 

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Mupi Ointment 5 gm, as it may worsen your condition or cause complications.

  • Severe kidney disease: Talk to your doctor before using this medicine on large, open wounds if you have kidney problems. Some formulations contain polyethylene glycol, which can be absorbed through broken skin and strain your kidneys.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS- TOPICAL ANTIBIOTICS/ANTIMICROBIALS]

FAQs

Mupi Ointment 5 gm is used to treat infections on the skin, including folliculitis (infected hair follicles that form pimples containing pus), impetigo (a contagious skin infection that causes blisters and crusting), and furunculosis or boils (recurring painful lumps filled with pus).
Your symptoms may improve before the infection is completely cured. But, it would be suggested to complete the full course of treatment even if you feel better.
For safe and effective use of Mupivate 2% Ointment 5 g, apply it only as prescribed for your skin condition and follow your doctor’s instructions carefully. Use a thin layer on the affected area, usually 2–3 times daily, and complete the full course even if symptoms improve. This ointment is for external use only; avoid the eyes, mouth, and mucous membranes. Do not use on large open wounds or severely damaged skin without medical advice. Stop use and seek medical attention if you experience severe irritation, rash, or an allergic reaction, and inform your doctor if you are pregnant, breastfeeding, or have any serious health conditions.
Apply a small amount of Mupi Ointment 5 gm, with a cotton swab or gauze pad to the affected area of the skin as per the dosage and schedule prescribed by your doctor.
Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not use extra medicine to make up for the missed dose.
While using Mupi Ointment 5 gm (mupirocin ointment), monitor your skin's response and whether the infection is improving. Mild burning, stinging, redness, or itching at the site is common and usually not serious. Stop using it and contact your doctor if you notice severe irritation, swelling, or a rash. Apply only to the affected area, avoid the eyes, nose, and mouth, and wash your hands before and after use. If the infection does not improve within a few days or gets worse, seek medical advice. This medicine is only effective for bacterial skin infections and will not treat viral or fungal problems.
It can be used in children, but it is not recommended for newborns under 4 weeks. Always follow your doctor’s guidance for pediatric use.
Avoid applying other topical medications on the same area unless your doctor approves, as this may reduce effectiveness or cause irritation.
You can use Mupi Ointment 5 gm on minor open wounds like infected cuts or scrapes, but you should avoid applying it to large, deep, or severely damaged skin areas without consulting your doctor first. Talk to your doctor for advice on treating extensive skin wounds.
Many people start to notice an improvement in their skin within a few days of starting treatment. However, you must continue using it for the full duration prescribed by your doctor to ensure the infection is completely gone. Talk to your doctor if you see no progress after 5 days.
Yes, you can apply Mupi Ointment 5 gm to your face to treat infections like impetigo, but you must keep it away from your eyes, nose, and mouth. If it accidentally gets into your eyes, rinse them thoroughly with plenty of water. Talk to your doctor if you experience eye irritation.
You should consult your doctor before using Mupi Ointment 5 gm if you are pregnant or planning to become pregnant. Your doctor will weigh the benefits and risks to decide if it is safe for you to use. Talk to your doctor for personalized guidance.
Do not use Mupi Ointment 5 gm to treat a diaper rash unless your child's pediatrician specifically prescribes it. Diaper rashes are often caused by yeast or skin irritation, which do not respond to this antibacterial medicine. Talk to your doctor for a proper diagnosis.
No, Mupi Ointment 5 gm is an antibacterial medicine and is not effective against fungal infections like athlete's foot or ringworm. Talk to your doctor or pharmacist to get the correct antifungal treatment for your symptoms.
Yes, you can cover the area with a sterile bandage or gauze dressing after applying Mupi Ointment 5 gm. This can help protect the wound and prevent you from touching or scratching it. Talk to your doctor to see if this is recommended for your specific infection.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.5405 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. U.S. Food and Drug Administration (FDA). 050591S034Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  4. Mupirocin [EMC Label]. 2011. [Accessed on 28 Mar. 2019] Check here
  5. Mupirocin [Prescribing Information]. [Accessed on 28 Mar. 2019] Check here
  6. Ema.Mupirocin. 2025 [Accessed on 17th September 2025] Check here
  7. Lactmed. Mupirocin. 2025 [Accessed on 17th September 2025] Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Mupirocin. 2025 [Accessed on 17th September 2025]Check here

Country of origin

India

Manufacturer/Marketer address

Office No. 11A ? 15, 1st Floor, Free Press House, 215, Nariman Point, Mumbai ? 400 021
Other Info - MUP0018

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