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Neksium 40 mg Tablet 10's

Neksium 40 mg Tablet 10's

Prescription drug
 Trailing icon

Manufacturer/Marketer

Pfizer Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

About Neksium 40 mg Tablet 10's

Neksium 40 mg Tablet 10's belongs to the class of drugs known as Proton pump inhibitor, which reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers and Zollinger-Ellison syndrome (overproduction of acid due to pancreatic tumour).

Neksium 40 mg Tablet 10's helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum. Neksium 40 mg Tablet 10's prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.

Take Neksium 40 mg Tablet 10's 1-2 hours prior to food. You are advised to take Neksium 40 mg Tablet 10's as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Neksium 40 mg Tablet 10's might cause common side effects like headache, diarrhoea, nausea, abdominal pain, and vomiting. Consult the doctor if the side effects persist or worsen. 

Neksium 40 mg Tablet 10's is safe for pregnant and breastfeeding mothers but should be taken only after consulting a doctor. Tell your doctor if you have stomach or intestinal cancer, liver problems, are allergic to Neksium 40 mg Tablet 10's, or will have an endoscopy in the future. Prolonged intake of Neksium 40 mg Tablet 10's may cause a deficiency of Vitamin B12 and low levels of calcium, magnesium, and Vitamin D, leading to osteoporosis.

Uses of Neksium 40 mg Tablet 10's

Treatment of Hyperacidity, Heartburn, Stomach ulcer, Zollinger-Ellison syndrome

Medicinal Benefits

Neksium 40 mg Tablet 10's is effective at healing erosive esophagitis (inflammation of food pipe), relieving symptoms of gastroesophageal reflux disease (heartburn), and Zollinger-Ellison syndrome. Neksium 40 mg Tablet 10's works by irreversibly blocking the proton pump gate (which secretes stomach acid). It can be prescribed to all age groups including special populations like the elderly, pregnant, lactating mothers, kidney, and liver disease patients. Usually, no dosage adjustment is required for these groups.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Suspension/Syrup: Shake the bottle well before use. Check the label for directions and take Neksium 40 mg Tablet 10's in doses as prescribed by your doctor with the help of a measuring cup.Powder/granules: Check the label for directions before use. Mix the powder/granules in water, mix well and drink immediately.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Neksium 40 mg Tablet 10's

  • Headache
  • Diarrhoea
  • Nausea
  • Abdominal pain
  • Vomiting

Drug Warnings

You should avoid taking Neksium 40 mg Tablet 10's if you are allergic to Neksium 40 mg Tablet 10's or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, pregnant or planning for pregnancy, and breastfeeding mothers. Neksium 40 mg Tablet 10's may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of Neksium 40 mg Tablet 10's may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B12, and magnesium deficiency. Intake of Neksium 40 mg Tablet 10's may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool) immediately consult the doctor. 

Drug Interactions

Drug-Drug Interactions: Neksium 40 mg Tablet 10's may interact with a blood thinner (clopidogrel, warfarin), antifungal (ketoconazole, voriconazole, itraconazole, posaconazole), anti-HIV drug (atazanavir, nelfinavir, rilpivirine),  anti-viral drugs (nelfinavir), iron supplements, antibiotic (ampicillin, rifampicin), heart medicine (digoxin) and anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines.

Drug-Food Interactions: Neksium 40 mg Tablet 10's interact with St John's wort plant that is used as an anti-depressant. This plant may affect the working of Neksium 40 mg Tablet 10's. So avoid its intake with Neksium 40 mg Tablet 10's.

Drug-Disease Interactions: Neksium 40 mg Tablet 10's should be not given in patients with Clostridium difficile associated diarrhea, magnesium and Vitamin B-12 deficiency (increased risk of bone fracture), atrophic gastritis (inflammed lining of stomach), and acute interstitial nephritis (inflammed cells of kidney).

Drug-Drug Interactions Checker List

  • CLOPIDOGREL
  • WARFARIN
  • KETOCONAZOLE
  • VORICONAZOLE
  • ITRACONAZOLE
  • POSACONAZOLE
  • ATAZANAVIR
  • NELFINAVIR
  • RILPIVIRINE
  • AMPICILLIN
  • RIFAMPICIN
  • DIGOXIN
  • METHOTREXATE

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Before going to sleep try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows, instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarette. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter) which prevents backflow of the stomach acid back into the food pipe.
  • Include high fibre containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidant, calcium and vitamin B 12 that can help cope with the long term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial in the peptic ulcer and H Pyroli infection.
  • Avoid regular sitting continuously, as it can increase stomach acid production. Try to take a break of 5 minutes in 1 hour by brisk walking or stretching.

Special Advise

Prolonged intake of Neksium 40 mg Tablet 10's may be associated with increased risk of Clostridium difficile associated diarrhea, magnesium and Vitamin B-12 deficiency (increased risk of bone fracture), atrophic gastritis (inflammed lining of stomach), and acute interstitial nephritis (inflammed cells of kidney).

 

Disease/Condition Glossary

Normally a thick layer of mucous protects the stomach against its own acid secretion. But, in long run, it gets eroded by excessive stomach acid production leading to complications like GERD, peptic ulcer, and Zollinger Ellison syndrome. Gastroesophageal reflux disease (GERD) is a gastrointestinal disorder that occurs when stomach acid frequently flows back into the food pipe (esophagus). This backflow (acid reflux) irritates the food pipe that causes heartburn. On the other hand, peptic ulcer is a painful condition followed by the development of sores or ulcers in the stomach lining or duodenum (first part of the small intestine) (the duodenum). Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting tumor of the pancreas causes excessive acid production leading to peptic ulcers.

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Alcohol

Caution

Drinking alcohol with Neksium 40 mg Tablet 10's may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol or contact doctor before intake of Neksium 40 mg Tablet 10's.

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Pregnancy

Caution

Neksium 40 mg Tablet 10's isn't usually recommended during pregnancy as there's no firm evidence it's safe. So, contact a doctor before intake of Neksium 40 mg Tablet 10's. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Neksium 40 mg Tablet 10's passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of Neksium 40 mg Tablet 10's. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Driving

Caution

In some cases, Neksium 40 mg Tablet 10's may cause dizziness, sleepy, or blur vision. If you observe these symptoms do not drive or operate heavy machinery until you feel better.

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Liver

Caution

Neksium 40 mg Tablet 10's should be taken with precaution in patients with liver disease.

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Kidney

Caution

Patients with kidney disease should consult a doctor before taking Neksium 40 mg Tablet 10's.

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Children

Caution

Neksium 40 mg Tablet 10's should not be prescribed for children under 5 years of age. Neksium 40 mg Tablet 10's is generally prescribed from 5-16 years of children for the treatment of acid-related damage of the food pipe (erosive esophagitis).

Country of origin

India

Manufacturer/Marketer address

Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Other Info -

FAQs

Neksium 40 mg Tablet 10's is used to treat Hyperacidity, Heartburn, Stomach ulcer, and Zollinger-Ellison syndrome.
Neksium 40 mg Tablet 10's is a proton pump inhibitor (PPI), which is a type of medication. Proton pumps are enzymes found in the stomach lining that aid in the production of acid needed for digestion. Esomeprazole impairs the function of proton pumps. This decreases the quantity of acid produced by the stomach.
No. Neksium 40 mg Tablet 10's prevents excess production of stomach acid causing acid reflux and heartburn. If blood is coming in your stool or mucous immediately contact the doctor.
Yes. Neksium 40 mg Tablet 10's can alter certain medical tests like neuroendocrine tumours (secretin stimulation test), and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test contact your doctor.
It is very unlikely that taking one or two extra doses by accident will cause any problems. However, you should check with your doctor if you have taken too much and have are feeling sweaty, have a fast heartbeat, are feeling sleepy.
There's no firm evidence to suggest that taking Neksium 40 mg Tablet 10's will reduce fertility in either men or women. However, speak to your doctor if you're trying to get pregnant and do as advised.
You can eat and drink normally while taking Neksium 40 mg Tablet 10's. However, you should avoid foods that seem to make your indigestion worse, such as rich, spicy and fatty foods. You should also cut down on caffeinated drinks, such as tea, coffee and cola, as well as alcohol.
No. Gas and acidity are two different common discomforts. Acidity is caused when improper functioning of the valve (sphincter) is located at the junction of the stomach and food pipe. As a result stomach acid backflows and enters the upper part of the food pipe causing heartburn. On the other hand, gas is the result of the digestion of the food and drinks eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc. from the body.
Prolonged intake of Neksium 40 mg Tablet 10's may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin enhancing medications to cope with long term side effects.

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