Norinfe 400 mg Tablet 10's
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About Norinfe 400 mg Tablet 10's
Norinfe 400 mg Tablet 10's is used to treat bacterial infections such as urinary tract infections, prostatitis (prostate inflammation), and gonorrhoea (a sexually transmitted disease). Additionally, Norinfe 400 mg Tablet 10's is used to treat infections of the stomach and intestine, such as traveler’s diarrhoea.
Norinfe 400 mg Tablet 10's contains norfloxacin, which works by inhibiting the bacterial enzyme DNA gyrase, thereby preventing bacterial DNA replication and leading to the death of the bacteria.
Take Norinfe 400 mg Tablet 10's as prescribed. In some cases, Norinfe 400 mg Tablet 10's may cause common side effects such as abdominal cramps, nausea, diarrhoea, heartburn, headache, and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
Take Norinfe 400 mg Tablet 10's as prescribed. It can be taken 1 hour before food or 2 hours after food. Swallow the medicine as a whole with a glass of water. The dose and duration of medicine will be decided by the physician.
Before taking Norinfe 400 mg Tablet 10's, inform your doctor if you are allergic to any of its ingredients or other fluoroquinolone antibiotics. Also, let your doctor know if you experience pain in tendons, swelling, or inflammation, as Norinfe 400 mg Tablet 10's is associated with an increased risk of tendon rupture and tendonitis in those who have had a kidney, heart, or lung transplant.
Uses of Norinfe 400 mg Tablet 10's
Norinfe 400 mg Tablet 10's is used for the treatment of bacterial infections. The detailed uses of Norinfe 400 mg Tablet 10's are as follows:
- Urinary Tract Infections (UTIs): Norinfe 400 mg Tablet 10's is an antibiotic used to treat complicated and uncomplicated urinary tract infections (UTIs) caused by certain bacteria.
- Gastrointestinal Infections: Norinfe 400 mg Tablet 10's can be used to treat infections of the stomach and intestine, such as traveller's diarrhoea.
- Prostatitis: Norinfe 400 mg Tablet 10's is also indicated for the treatment of prostatitis, an inflammation of the prostate gland often caused by bacterial infection.
- Gynecological Infections: Norinfe 400 mg Tablet 10's treats certain bacterial gynecological infections, especially those affecting the lower reproductive system, such as cervical and urethral gonorrhea caused by the bacteria Neisseria gonorrhoeae.
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Directions for Use
- Norinfe 400 mg Tablet 10's should be taken at least 1 hour before or 2 hours after a meal.
- It is usually taken twice daily or as prescribed by your doctor.
- Swallow Norinfe 400 mg Tablet 10's as a whole with a glass of water.
- Do not crush, chew, break, or open it.
Key Benefits
- Norinfe 400 mg Tablet 10's belongs to the group of medicines called quinolone antibiotics, used to treat bacterial infections.
- Additionally, Norinfe 400 mg Tablet 10's is also used to treat traveller’s diarrhoea.
- Norinfe 400 mg Tablet 10's is bactericidal in nature. It works by inhibiting the synthesis of bacterial DNA gyrase, thereby preventing the bacteria from repairing and multiplying, and ultimately killing them and treating infections.
- Norinfe 400 mg Tablet 10's is a broad-spectrum antibiotic effective against a wide range of gram-positive and gram-negative bacteria.
How Norinfe 400 mg Tablet 10's Works
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- Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
- Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
- When standing up, do so slowly and carefully to avoid sudden dizziness.
- Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
- Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
- If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
- Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
- Rest well; get enough sleep.
- Eat a balanced diet and drink enough water.
- Manage stress with yoga and meditation.
- Limit alcohol and caffeine.
- Physical activities like walking or jogging might help boost energy and make you feel less tired.
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
What if I have taken an overdose of Norinfe 400 mg Tablet 10's
Drug Warnings
- Do not take Norinfe 400 mg Tablet 10's if you are allergic to any of its ingredients
- Also, inform your doctor if you have experienced swelling or tendon tearing while taking quinolone antibiotics.
- Norinfe 400 mg Tablet 10's is associated with an increased risk of tendonitis and tendon rupture in all age groups; this risk is higher in patients over 60 years old, those taking corticosteroids, or those who have had kidney, heart, or lung transplants.
- Consult your doctor immediately if you experience tendon pain, swelling, or inflammation while taking Norinfe 400 mg Tablet 10's.
- Do not take Norinfe 400 mg Tablet 10's if you have myasthenia gravis, as it may cause increased muscle weakness.
- Talk to your doctor if you have epilepsy, low potassium levels, nervous or muscle disorders, head injury or brain tumour, diabetes, rheumatoid arthritis, or heart, kidney, or liver problems.
- Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking Norinfe 400 mg Tablet 10's.
- Avoid alcohol consumption while taking Norinfe 400 mg Tablet 10's, as it may increase dizziness.
- Norinfe 400 mg Tablet 10's may cause dizziness and vision problems, so avoid driving or operating machinery until you are fully alert.
Drug-Drug Interactions
Drug-Drug Interactions
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The combination of Amiodarone and Norinfe 400 mg Tablet may significantly raise the risk of an abnormal heart rhythm.
How to manage the interaction:
Despite the fact that Amiodarone and Norinfe 400 mg Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
Using bepridil together with Norinfe 400 mg Tablet can increase the risk of an irregular heart rhythm that may be serious.
How to manage the interaction:
Taking Norinfe 400 mg Tablet with Bepridil is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or a fast or pounding heartbeat. Do not stop using any medications without talking to a doctor.
Coadministration of Norinfe 400 mg Tablet with Cisapride can increase the risk or severity of irregular heart rhythm.
How to manage the interaction:
Taking Norinfe 400 mg Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
Using Mesoridazine together with Norinfe 400 mg Tablet can increase the risk of an irregular heart rhythm that may be serious.
How to manage the interaction:
Taking Mesoridazine with Norinfe 400 mg Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
Coadministration of Norinfe 400 mg Tablet with Sotalol can increase the risk or severity of irregular heart rhythm.
How to manage the interaction:
Taking Norinfe 400 mg Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
Coadministration of Norinfe 400 mg Tablet with Disopyramide can increase the risk of irregular heart rhythm.
How to manage the interaction:
Taking Norinfe 400 mg Tablet with Disopyramide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
Coadministration of Norinfe 400 mg Tablet with Papaverine can increase the risk or severity of irregular heart rhythm.
How to manage the interaction:
Taking Norinfe 400 mg Tablet with Papaverine together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
Using Ribociclib together with Norinfe 400 mg Tablet can increase the risk of an irregular heart rhythm that may be serious.
How to manage the interaction:
Taking Norinfe 400 mg Tablet with Ribociclib together can result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like a slow heart rate, irregular heart rhythm, dizziness, fainting, or trouble breathing, you should call your doctor right away. Do not stop using any medications without talking to a doctor.
Coadministration of Norinfe 400 mg Tablet with Iloperidone can increase the risk or severity of irregular heart rhythm.
How to manage the interaction:
Taking Norinfe 400 mg Tablet with Iloperidone together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
Taking insulin degludec with Norinfe 400 mg Tablet affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.
How to manage the interaction:
There could be a possible interaction between insulin degludec and Norinfe 400 mg Tablet but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu, Orange Juice
How to manage the interaction:
Consuming dairy products, cereal, or orange juice with Norinfe 400 mg Tablet can interfere with its absorption and reduce its levels in the blood and urinary tract. Using caffeine together with Norinfe 400 mg Tablet may increase the effects of caffeine. Norinfe 400 mg Tablet dose should be taken at least one hour before or two hours after consuming dairy products, cereal, or orange juice. Avoid taking caffeine with Norinfe 400 mg Tablet. Contact a doctor if you experience headaches, tremors, restlessness, nervousness, insomnia, and increased blood pressure or heart rate.
Diet & Lifestyle Advise
- Antibiotics can alter the beneficial bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
- Eat fiber-rich food like whole grains, beans, lentils, berries, broccoli, peas, and bananas.
- Avoid foods rich in calcium, such as dairy products and grapefruit and grapefruit juice, as they may hinder the absorption of antibiotics.
- Avoid consumption of alcohol and usage of tobacco.
Habit Forming
Therapeutic Class
Alcohol
Safe if prescribed
Avoid consuming alcohol while taking Norinfe 400 mg Tablet 10's, as it may cause increased dizziness.
Pregnancy
Consult your doctor
Norinfe 400 mg Tablet 10's belongs to pregnancy category C. Please consult your doctor if you are pregnant or planning to become pregnant. Your doctor will prescribe Norinfe 400 mg Tablet 10's only if the benefits outweigh the risks.
Breast Feeding
Consult your doctor
It is unknown if Norinfe 400 mg Tablet 10's passes into breastmilk. Consult your doctor if you are breastfeeding before taking Norinfe 400 mg Tablet 10's.
Driving
Safe if prescribed
Norinfe 400 mg Tablet 10's may cause dizziness and light-headedness. So, drive only if you are alert.
Liver
Consult your doctor
Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease.
Kidney
Consult your doctor
Dose adjustment may be needed. Please consult your doctor if you have kidney impairment/kidney disease.
Children
Safe if prescribed
Norinfe 400 mg Tablet 10's is not recommended for children below 18 years, as its safety and effectiveness have not been established in this age group.
Heart
Norinfe 400 mg Tablet 10's should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Norinfe 400 mg Tablet 10's.
Geriatrics
Consult your doctor
Norinfe 400 mg Tablet 10's should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.
FAQs
Norinfe 400 mg Tablet 10's is used to treat bacterial infections caused by susceptible bacteria. It is indicated in the treatment of urinary tract infections‚ prostatitis (prostate inflammation), and gonorrhoea (a sexually transmitted disease). Additionally, Norinfe 400 mg Tablet 10's is used to treat infections of the stomach and intestine, such as traveller's diarrhoea.
Norinfe 400 mg Tablet 10's contains Norfloxacin, which works by inhibiting the synthesis of an enzyme called DNA gyrase. Thereby, it kills the bacteria and treats bacterial infections.
Norinfe 400 mg Tablet 10's may cause photosensitivity (sensitivity to sunlight) and increase your risk of sunburn. Avoid prolonged exposure to sunlight or tanning beds. Always wear protective clothing and sunscreen with an SPF of 30 or higher before going outdoors.
It is recommended to complete the course of Norinfe 400 mg Tablet 10's, even if you feel better, as it is an antibiotic, and leaving it incomplete may lead to a more severe infection. To treat your condition effectually, continue taking Norinfe 400 mg Tablet 10's for as long as your doctor has prescribed it.
Avoid consuming dairy products, such as milk and yoghurt, along with Norinfe 400 mg Tablet 10's, as they may decrease the effectiveness of Norinfe 400 mg Tablet 10's.
Do not take Norinfe 400 mg Tablet 10's on your own, as self-medication may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections.
Maintain a minimum gap of two hours between Norinfe 400 mg Tablet 10's and antacids, anti-ulcer medications (such as sucralfate), anti-HIV medications (like didanosine), and vitamin and mineral supplements. However, consult your doctor before taking other medicines with Norinfe 400 mg Tablet 10's.
Consult your doctor before taking Norinfe 400 mg Tablet 10's if you have diabetes, as Norinfe 400 mg Tablet 10's may cause hypoglycaemia (low blood sugar levels). Regularly monitor blood sugar levels while taking Norinfe 400 mg Tablet 10's to avoid hypoglycaemic events.
Norinfe 400 mg Tablet 10's may cause changes in liver function tests and prothrombin time (time taken for blood clotting). Inform the person doing the tests that you are taking Norinfe 400 mg Tablet 10's.
If you start feeling better, do not stop taking the medicine on your own. Instead, please inform your doctor about your progress and follow their advice. Completing the entire course of therapy is crucial to ensure the infection is fully treated and does not return. Your doctor will guide you on the next steps, so be sure to check in with them.
Common side effects of Norinfe 400 mg Tablet 10's may include abdominal cramps, nausea, headache, and dizziness. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if the side effects persist or worsen.
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Reference
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/019384s066lbl.pdf
- https://www.drugs.com/mtm/norfloxacin.html
- https://www.medsafe.govt.nz/consumers/cmi/a/arrow-norfloxacin.pdf
- https://www.nps.org.au/assets/medicines/79780e54-983f-4464-89f5-a53300feeb23-reduced.pdf
- https://www.efda.gov.et/wp-content/uploads/2023/08/Norfloxacin_Norfloxacin-Tablets_medicamen-Biotech-Ltd.pdf
