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compositionComposition:OBETICHOLIC ACID-5MG
prescription
Prescription Medicine
info
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Obiholic 5 Tablet is used to treat primary biliary cirrhosis (an autoimmune disease caused by damage of bile ducts in the liver). This medicine helps reduce bile acid buildup in the liver and slows the progression of liver damage and fibrosis.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

OBETICHOLIC ACID-5MG

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Obiholic 5 Tablet

Obiholic 5 Tablet is a prescription medicine used to treat a chronic liver disease called primary biliary cholangitis (PBC). It is usually prescribed together with ursodeoxycholic acid (UDCA) when UDCA alone is not working well enough. For people who cannot tolerate UDCA, Obiholic 5 Tablet may be used on its own. Obiholic 5 Tablet helps protect the liver by reducing the buildup of harmful bile acids that can damage liver cells over time.

Obiholic 5 Tablet is typically taken once daily as an oral tablet, and it can be taken with or without food. To get the best results, it is important to take it consistently every day at the same time. Combining this treatment with a low-sodium diet and staying well-hydrated can also support your overall liver health.

Some people may experience side effects like severe skin itching, joint pain, or feeling very tired. If you notice severe itching or signs that your liver function is getting worse, you must contact your doctor immediately. Your healthcare team will monitor you closely to ensure Obiholic 5 Tablet is working safely.

Do not take this if you have a complete blockage of your bile ducts or severe liver damage with complications. Before starting, tell your doctor if you have other liver problems, as Obiholic 5 Tablet may not be suitable for you. It is also important to share your complete medical history to prevent complications.

Obiholic 5 Tablet can interact with other drugs, especially those that bind bile acids, which can lower its effectiveness. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, talk to your doctor about the risks and benefits before starting treatment.

Uses of Obiholic 5 Tablet

Obiholic 5 Tablet is used in the treatment of Primary biliary cirrhosis. The detailed uses of Obiholic 5 Tablet are as follows:

  • Primary Biliary Cholangitis (PBC): Obiholic 5 Tablet helps by slowing down the progression of this chronic liver disease. It reduces the amount of harmful bile acids that your liver produces, preventing them from building up and causing permanent liver damage.

Key Benefits

Obiholic 5 Tablet helps manage primary biliary cholangitis (PBC) by improving bile flow and reducing the buildup of harmful bile acids in the liver. By protecting the liver from ongoing damage, it supports long-term liver health and function.

Benefits may include:

  • Helps reduce harmful bile acid buildup in the liver.
  • Supports healthy liver function and helps slow the progression of primary biliary cholangitis.
  • Helps reduce liver inflammation and scarring.
  • Lowers liver enzyme levels, such as alkaline phosphatase (ALP), indicating improved liver health.
  • May help delay the progression of liver disease and reduce the risk of liver-related complications.
  • Supports long-term liver health and overall quality of life when used as prescribed.
Side effects of Obiholic 5 Tablet
  • Include omega-3 rich foods in your diet to reduce inflammation.
  • Eat antioxidant-rich foods like fruits, vegetables, and nuts to promote overall skin health.
  • Stay hydrated by drinking plenty of water.
  • Maintain a healthy skin care routine, using gentle, fragrance-free products.
  • Wear loose, breathable clothing to minimize irritation.
  • Keep fingernails short and clean to prevent further skin damage.
  • Use a humidifier to add moisture to the air, reducing dryness and itchiness.
  • Practice stress-reducing techniques like meditation or deep breathing to manage stress levels.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Throat pain can worsen if there is no proper rest for your throat.
  • Drink plenty of warm fluids and frequently gargle with salt water.
  • Humidify the surrounding air using a humidifier, as dry air may increase dryness and throat pain.
  • Consider taking lozenges or hard candy throat pain relievers, which give a soothing effect.
  • Take enough rest and stay in warm places to reduce pain quickly.

Directions for Use

  • Obiholic 5 Tablet can be taken with food to prevent stomach upset.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow Obiholic 5 Tablet as a whole with a glass of water.
  • Do not break, chew, or crush it.

How Obiholic 5 Tablet Works

Obiholic 5 Tablet helps reduce the production of bile acids in the liver and improves the flow of bile. This helps prevent bile from building up in the liver, protects liver cells from damage, and helps reduce inflammation and scarring, supporting better liver function.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Obiholic 5 Tablet . Consult your doctor if you have any concerns.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant, as limited information is available regarding the usage of Obiholic 5 Tablet during pregnancy.

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Breast Feeding

Consult your doctor

Consult your doctor if you are breastfeeding; your doctor will decide whether Obiholic 5 Tablet can be taken by breastfeeding mothers or not.

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Driving

Safe if prescribed

Obiholic 5 Tablet does not affect your ability to drive. However, you are advised to omit driving if you experience dizziness.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this. Inform your doctor if you have/had liver cirrhosis.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Obiholic 5 Tablet is not recommended for children or adolescents.

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Heart

Caution

Obiholic 5 Tablet should be used with caution in patients with heart disease due to increased risk of side effects. Therefore, please consult your doctor before using Obiholic 5 Tablet .

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Geriatrics

Caution

Obiholic 5 Tablet should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Obiholic 5 Tablet .

What if I have taken an overdose of Obiholic 5 Tablet

If you take more than your prescribed dose, seek immediate medical attention or contact your local poison control center. An overdose can lead to severe side effects, particularly affecting your liver.

Diet & Lifestyle Advise

  • Follow a low-sodium diet: Reducing salt intake helps manage and prevent fluid retention, which is a common concern in chronic liver conditions.
  • Avoid alcohol entirely: Alcohol adds extra stress to your liver and can speed up liver damage. It is highly recommended to stop drinking alcohol while on this medication.
  • Manage skin itching: To help control itching, take cool or lukewarm baths, wear loose-fitting cotton clothing, and apply gentle, fragrance-free moisturizers.
  • Stay hydrated: Drink plenty of water throughout the day to support your body's normal functions and help your kidneys and liver work effectively.
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How Soon It Starts Working

  • The time required for Obiholic 5 Tablet to start to work: The time required for Obiholic 5 Tablet to show its action is unknown.
  • The time for which the effects of Obiholic 5 Tablet last: The duration of action for Obiholic 5 Tablet is clinically unknown.

What if you forget to take Obiholic 5 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose entirely and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store Obiholic 5 Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Attend regular monitoring appointments: Keep all scheduled blood tests so your doctor can monitor your liver enzymes, bilirubin levels, and overall liver function throughout treatment.
  • Monitor for worsening itching: Tell your doctor if you develop new or worsening itching, as your dose may need to be adjusted or additional treatment may be required.
  • Do not change or stop treatment without medical advice: Never stop taking Obiholic 5 Tablet or change your dose unless instructed by your healthcare provider.
  • Separate bile acid-binding medicines from your dose: If you take bile acid-binding medicines, follow your doctor's instructions on the timing of each dose to help prevent them from reducing the absorption of Obiholic 5 Tablet .
  • Use with caution in advanced liver disease: If you have advanced liver disease or cirrhosis with complications, Obiholic 5 Tablet requires careful dose selection and close monitoring, as incorrect dosing may increase the risk of serious liver problems.
  • Discuss pregnancy and breastfeeding with your doctor: Tell your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding before starting Obiholic 5 Tablet , as your doctor will carefully assess the potential benefits and risks of treatment.

Drug-Drug Interactions

verifiedApollotooltip
  • Bile acid-binding medicines (e.g., cholestyramine, colestipol, colesevelam): These medicines may reduce the absorption and effectiveness of Obiholic 5 Tablet . Take Obiholic 5 Tablet at least 4 hours before or 4 hours after these medicines.
  • Certain medicines processed by the liver (e.g., theophylline): Obiholic 5 Tablet may increase the levels of these medicines in the body, raising the risk of side effects. Your doctor may monitor you more closely or adjust the dose if needed.
Obeticholic acidTizanidine
Severe

Drug-Drug Interactions

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Obeticholic acidTizanidine
Severe
How does the drug interact with Obiholic 5 Tablet:
Coadministration of Tizanidine and Obiholic 5 Tablet can increase tizanidine's blood levels and risk of side effects.

How to manage the interaction:
Co-administration of Tizanidine and Obiholic 5 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, contact your doctor immediately if you experience drowsiness, dizziness, lightheadedness, fainting, and irregular heart rhythm. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Obiholic 5 Tablet when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Obiholic 5 Tablet helps improve liver functioning by reducing the production and build-up of bile in the liver and reducing inflammation.
Do not discontinue Obiholic 5 Tablet without consulting your doctor. To treat your condition effectually, continue taking Obiholic 5 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Obiholic 5 Tablet .
Constipation might be a side-effect of Obiholic 5 Tablet . Drink lots of fluids and eat fibre-rich food if you experience constipation. Talk to your doctor if you have severe constipation.
Obiholic 5 Tablet may cause palpitation, a sensation that the heart is racing, pounding, or fluttering. A minor fluctuation should not be a worry; however, if palpitations continue or you begin to feel unwell, speak with your doctor.
Obiholic 5 Tablet is used to treat primary biliary cholangitis (PBC), an autoimmune liver disease. Adults with PBC and individuals who haven't responded to other treatments may need to take OCA, but only if advised by their doctor.
You can use Obiholic 5 Tablet combined with ursodeoxycholic acid to treat primary biliary cholangitis (PBC), but only if your doctor advises.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimise side effects.
Common side effects of Obiholic 5 Tablet may include stomach pain, tiredness, dizziness, constipation, and palpitations. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if the side effects persist or worsen.
Obiholic 5 Tablet is not recommended for children or adolescents.
Obiholic 5 Tablet is used to treat primary biliary cholangitis (PBC), a chronic autoimmune liver disease in which the bile ducts are gradually damaged. It may be used in adults whose response to ursodeoxycholic acid (UDCA) is inadequate or who cannot tolerate UDCA. Your doctor will determine whether Obiholic 5 Tablet is appropriate for you.
No, Obiholic 5 Tablet does not cure primary biliary cholangitis, but it helps slow down the progression of the disease and protects your liver from further damage. Talk to your doctor about what to expect from long-term treatment.
Bile acid-binding medicines such as cholestyramine, colestipol, and colesevelam can reduce the absorption of Obiholic 5 Tablet . Take Obiholic 5 Tablet at least 4 hours before or 4 hours after these medicines. Your doctor or pharmacist can help you plan an appropriate dosing schedule.
Itching is a very common side effect. If it becomes severe or hard to manage, contact your doctor right away, as they may need to adjust your dose or prescribe a treatment to relieve the itching. Talk to your doctor before making any changes.
It is highly recommended to avoid alcohol completely while taking Obiholic 5 Tablet . Alcohol puts extra stress on your liver and can worsen your liver condition. Talk to your doctor about safe lifestyle choices for your liver health.
There is limited information about the safety of Obiholic 5 Tablet during pregnancy. If you are pregnant, planning to become pregnant, or think you may be pregnant, discuss the potential benefits and risks with your doctor before starting or continuing treatment.
Regular blood tests allow your doctor to check your liver enzymes and overall liver function to ensure Obiholic 5 Tablet is working safely and effectively. Talk to your doctor about your scheduled monitoring plan.
Watch for yellowing of your skin or eyes, unusually dark urine, severe stomach swelling, pale stools, or mental confusion. If you notice any of these signs, seek medical care immediately. Talk to your doctor if you experience any new symptoms.
Primary biliary cholangitis is a long-term condition, so treatment with Obiholic 5 Tablet is often continued for an extended period if it is working well and you tolerate it. Your doctor will regularly review your liver function and decide whether you should continue treatment.
Your doctor will regularly review your blood test results and symptoms to see how well the treatment is working. If your liver tests do not improve or your disease continues to progress, your doctor may adjust your treatment plan or discuss other treatment options. Do not stop taking Obiholic 5 Tablet unless your doctor advises you to.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase III, New Delhi - 110020.
Other Info - OBI0076

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