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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pgut-3 Combipack 1's is used in the treatment of peptic ulcer disease caused by infection with a common type of bacteria called Helicobacter pylori (H. pylori). It kills bacteria or prevents their growth. Also, it reduces the amount of acid produced in the stomach. It may cause common side effects, such as nausea, diarrhoea, vomiting, stomach pain, taste change, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Spinogen

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pgut-3 Combipack 1's

Pgut-3 Combipack 1's is used in the treatment of peptic ulcer disease caused by infection with a common type of bacteria called Helicobacter pylori (H. pylori). Peptic ulcers are sores (small, shallow wounds) that develop on the intestine and stomach's inner lining.

Pgut-3 Combipack 1's is a combination of three drugs, namely: Pantoprazole, amoxycillin, and clarithromycin. Amoxycillin works by preventing the formation of bacterial cell covering (protective cell wall) necessary for their survival, thereby preventing the growth of bacteria. Clarithromycin stops bacterial growth but does not necessarily kill them. Pantoprazole reduces the amount of acid produced in the stomach. Altogether, Pgut-3 Combipack 1's helps treat peptic ulcer disease.

In some cases, you may experience certain common side effects, such as nausea, diarrhoea, vomiting, stomach pain, taste change, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Pgut-3 Combipack 1's if you are pregnant or breastfeeding unless prescribed by the doctor. Pgut-3 Combipack 1's causes drowsiness, so drive only if you are alert. Pgut-3 Combipack 1's should not be given to children as safety has not been established. Avoid consuming alcohol along with Pgut-3 Combipack 1's as it could lead to increased drowsiness and can elevate the production of stomach acid.

Uses of Pgut-3 Combipack 1's

Pgut-3 Combipack 1's is used in the treatment of Peptic ulcer disease. The detailed uses of Pgut-3 Combipack 1's are as follows:

  • Treat peptic ulcers caused by H. pylori infection: Pgut-3 Combipack 1's is primarily used to eradicate Helicobacter pylori, a bacterium responsible for stomach and intestinal ulcers. Amoxycillin and Clarithromycin are antibiotics that kill or inhibit bacterial growth, while Pantoprazole reduces stomach acid to promote healing.
  • Manage acid-related gastrointestinal disorders: Pgut-3 Combipack 1's helps relieve symptoms of acid reflux, heartburn, and gastritis by lowering gastric acid production. This creates a less acidic environment, allowing ulcers and inflamed tissues to recover.
  • Prevent recurrence of ulcers and complications: Pgut-3 Combipack 1's is also used to prevent the return of ulcers and reduce the risk of gastrointestinal bleeding or perforation. Its combination action approach ensures both bacterial eradication and mucosal protection.

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Directions for Use

  • Take Pgut-3 Combipack 1's 30-60 minutes before food as advised by your doctor.
  • It is advised to take Pgut-3 Combipack 1's as directed by your doctor, at the same time each day for best results.
  • Swallow Pgut-3 Combipack 1's as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Pgut-3 Combipack 1's effectively treats Helicobacter pylori (H. pylori) infection in the stomach.
  • Helps heal and prevent recurrence of peptic ulcers and gastric or duodenal ulcers.
  • Pantoprazole reduces stomach acid production, creating a favourable environment for ulcer healing.
  • Amoxycillin and clarithromycin work together to eliminate the H. pylori bacteria causing infection.
  • Reduces symptoms such as heartburn, acidity, stomach pain, bloating, and indigestion.
  • Offers a triple therapy approach for complete eradication of the infection.
  • Improves digestive comfort and promotes long-term gastrointestinal health.

How Pgut-3 Combipack 1's Works

Pgut-3 Combipack 1's is a combination of three drugs, namely: Pantoprazole, amoxycillin, and clarithromycin. Amoxycillin is bactericidal (kills bacteria) and works by preventing the formation of the bacterial cell wall (protective cell wall) necessary for their survival, thereby preventing bacterial growth. Clarithromycin is a bacteriostatic antibiotic; i.e., it stops bacterial growth but does not necessarily kill them. It works by inhibiting the protein synthesis required for bacterial cell growth. As a result, bacterial cells cannot reproduce or grow. Pantoprazole is a proton pump inhibitor that works by blocking the action of an enzyme called the gastric proton pump, which is responsible for the production of acid in the stomach. Thereby reduces the amount of acid produced in the stomach. Altogether, Pgut-3 Combipack 1's helps treat peptic ulcer disease.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Pgut-3 Combipack 1's

Do not take more than the prescribed dose of Pgut-3 Combipack 1's as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Inform your doctor before taking Pgut-3 Combipack 1's if you have a history of liver disease, kidney disease, or myasthenia gravis (neuromuscular disease).
  • Do not take Pgut-3 Combipack 1's if you are pregnant or breastfeeding unless prescribed by the doctor.
  • Pgut-3 Combipack 1's causes drowsiness, so drive only if you are alert.
  • Pgut-3 Combipack 1's should not be given to children as safety has not been established.
  • Avoid consuming alcohol along with Pgut-3 Combipack 1's as it could lead to increased drowsiness and can elevate the production of stomach acid.
  • Keep your doctor informed about all the medicines and your health condition to rule out any side effects.

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Avoid tight-fitting clothes.
  • Avoid foods such as high-fat, spicy foods, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
  • Avoid sitting continuously, as it may trigger acidity. Take a 5-minute break every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTIULCERS

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pgut-3 Combipack 1's. Alcohol intake leads to increased production of stomach acid.

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Pregnancy

Consult your doctor

Consult your doctor before taking Pgut-3 Combipack 1's if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Pgut-3 Combipack 1's. Your doctor will decide whether Pgut-3 Combipack 1's can be taken by breastfeeding mothers or not.

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Driving

Caution

Pgut-3 Combipack 1's causes dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Pgut-3 Combipack 1's if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Pgut-3 Combipack 1's if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Pgut-3 Combipack 1's should not be given to children as the safety and effectiveness were not established.

FAQs

Pgut-3 Combipack 1's is used in the treatment of peptic ulcer disease caused by infection with a common type of bacteria called Helicobacter pylori (H. pylori). It works by inhibiting the action of the gastric proton pump and preventing the growth of microorganisms.

Speak to your doctor if you do not feel better even after taking Pgut-3 Combipack 1's for 14 days. Do not take Pgut-3 Combipack 1's for longer durations unless prescribed by the doctor.

Pgut-3 Combipack 1's may cause dizziness. Drive only if you are alert, and do not operate machinery if you feel dizzy after taking Pgut-3 Combipack 1's.

Avoid or limit the consumption of alcohol while on Pgut-3 Combipack 1's as it may lead to increased dizziness. Alcohol intake may also lead to excess production of stomach acid, thereby increasing acidity and heartburn.

Diarrhoea might be a side-effect of Pgut-3 Combipack 1's. Drink enough fluids and eat fibre-rich food if you experience diarrhoea after taking Pgut-3 Combipack 1's. If you find blood in your stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Pgut-3 Combipack 1's contains pantoprazole, which may increase the risk of bone fracture in the hip, spine, or wrist. Recent clinical studies indicated that pantoprazole may affect the absorption of certain nutrients and minerals required for maintaining good bone health, leading to fractures. This mainly occurs in people taking higher doses of Pgut-3 Combipack 1's for longer durations. Inform your doctor before taking Pgut-3 Combipack 1's if you have osteoporosis or if you are already taking corticosteroids.

Dry mouth could be a side effect of Pgut-3 Combipack 1's. Limiting caffeine intake, avoiding smoking, drinking enough water, and chewing sugar-free gum or candy might help stimulate saliva production and thereby prevent dry mouth.

Inform your doctor if you don’t get better after finishing the full course of treatment. Also, let your doctor know if your symptoms are getting worse while using Pgut-3 Combipack 1's. Your doctor may need to reassess your condition, possibly perform additional tests, and prescribe a different treatment if necessary.

A peptic ulcer is a sore that develops on the lining of your stomach, lower esophagus, or small intestine. It's usually caused by an infection with Helicobacter pylori (H. pylori) bacteria or prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs).

Do not use Pgut-3 Combipack 1's if you have a known hypersensitivity to Pgut-3 Combipack 1's. Use Pgut-3 Combipack 1's with caution if you have liver disease, as the antibiotics in Pgut-3 Combipack 1's can affect liver function. Inform your doctor if you have or ever had gastrointestinal bleeding, diabetes, myasthenia gravis (neuromuscular disease), bone fractures, or hypomagnesemia (low levels of magnesium). Also, let your doctor know if you are breastfeeding, pregnant or planning pregnancy.

Take Pgut-3 Combipack 1's 30-60 minutes before food or as advised by your doctor. Swallow it as a whole with a glass of water. But try to take it at the same time each day for better efficacy. Do not crush or chew it.

No, do not stop using Pgut-3 Combipack 1's even if you feel better, as stopping Pgut-3 Combipack 1's early can leave the infection untreated, which could lead to side effects. Therefore, complete the full course of treatment as prescribed by your doctor.

Common side effects of Pgut-3 Combipack 1's include nausea, diarrhoea, vomiting, stomach pain, altered taste, and headache. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Near, GSPL Tower, E304, Second Floor Industrial Area, Phase 8, Godrejj, Sahibzada Ajit Singh Nagar, Punjab 160055
Other Info - PGU0004

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