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  3. PH Plus D Capsule 10's

PH Plus D Capsule 10's, Pack of 10 CAPSULES
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

PH Plus D Capsule is used to treat acidity-related conditions, nausea, vomiting, and upper abdominal discomfort. It contains pantoprazole and domperidone, which work by reducing stomach acid production and improving stomach and intestinal motility. In some cases, this medicine may cause side effects like diarrhoea, stomach pain, flatulence (gas), dry mouth, dizziness, and headache. Before starting PH Plus D Capsule , let the doctor know if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Composition :

DOMPERIDONE-30 + PANTOPRAZOLE-40

Manufacturer/Marketer :

Cogentrix Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About PH Plus D Capsule

PH Plus D Capsule is indicated in the treatment of gastro-oesophageal reflux disease (acid reflux), erosive esophagitis (inflammation of the oesophagus due to acid reflux), and gastric and duodenal ulcers. Additionally, it is also used to relieve symptoms of nausea and vomiting, upper abdominal discomfort, feeling of discomfort, and regurgitation of gastric contents.

PH Plus D Capsule contains pantoprazole and domperidone. Pantoprazole works by reducing the amount of acid made by the stomach. Domperidone works by increasing the movements of the stomach and intestines. Together, PH Plus D Capsule helps treat acidity-related conditions.

The most common side effects of PH Plus D Capsule are diarrhoea, stomach pain, flatulence (gas), dry mouth, dizziness, and headache. Most of these side effects may not require medical attention and resolve over time. However, if the side effects persist or worsen, consult your doctor.

Do not take PH Plus D Capsule if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. PH Plus D Capsule is not recommended for children below 12 years. Keep the doctor informed about your health condition and medications to prevent any interactions.

Uses of PH Plus D Capsule

PH Plus D Capsule is used in the treatment of Gastroesophageal reflux disease (GERD), Heartburn due to hyperacidity, Inflammation of the food pipe (esophagitis), and Peptic ulcers. The detailed uses of PH Plus D Capsule are as follows:

  • Gastroesophageal Reflux Disease (GERD): PH Plus D Capsule is commonly used to alleviate GERD symptoms and lower stomach acid production by relieving heartburn and acid reflux.
  • Peptic Ulcers: PH Plus D Capsule is useful in treating peptic ulcers, assisting in healing and minimising ulcer recurrence by regulating gastric acid output.
  • Dyspepsia: PH Plus D Capsule is usually given to treat dyspeptic symptoms such as bloating, nausea, and discomfort by improving stomach motility.
  • Zollinger-Ellison Syndrome: PH Plus D Capsule is used to treat Zollinger-Ellison syndrome, a disorder marked by increased stomach acid production, and it aids in reducing the symptoms and problems associated with the condition.
  • Inflammation of the food pipe (esophagitis): PH Plus D Capsule is also involved in treating esophagitis and works by blocking the gastric proton pump to relieve symptoms and promote healing.

Directions for Use

  • PH Plus D Capsule should be taken 30-60 minutes before a meal to enhance absorption and effectiveness.
  • It is usually taken once daily in the morning or as advised by your doctor. If prescribed twice daily, take the second dose before dinner.
  • Swallow PH Plus D Capsule as a whole with a glass of water.
  • Do not crush, chew, open, or break it.

Medicinal Benefits

  • PH Plus D Capsule is indicated in the treatment of acidity-related conditions, such as heartburn, gastro-oesophageal reflux disease (acid reflux), erosive esophagitis (inflammation of the oesophagus due to acid reflux), and gastric and duodenal ulcers.
  • It is also used to relieve symptoms such as nausea and vomiting, upper abdominal discomfort, bloating, and regurgitation of gastric contents.
  • PH Plus D Capsule contains pantoprazole and domperidone. Pantoprazole is a proton pump inhibitor which works by reducing the amount of acid produced in the stomach. Domperidone is a prokinetic that works by improving the movement of the stomach and intestines.
  • PH Plus D Capsule helps manage acidity-related conditions, promotes digestion, and provides relief from associated discomfort.

How PH Plus D Capsule Works

PH Plus D Capsule contains pantoprazole (proton pump inhibitor) and domperidone (prokinetic). Pantoprazole works by reducing the amount of acid made by the stomach. Domperidone works by increasing the motility of the stomach and intestines. Together, PH Plus D Capsule helps treat acidity-related conditions, nausea, vomiting, and abdominal discomfort.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of PH Plus D Capsule
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.

What if I have taken an overdose of PH Plus D Capsule

Do not take more than the prescribed dose of PH Plus D Capsule as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take PH Plus D Capsule if you are allergic to any of its components.
  • Inform the doctor if you have kidney, liver or heart problems, osteoporosis, high levels of calcium, blockage in the intestines, prolactinoma (prolactin-releasing pituitary tumour), or any other health condition.
  • Prolonged intake of PH Plus D Capsule may increase the risk of cyanocobalamin deficiency, Clostridium difficile-associated Diarrhoea (CDAD), bone fractures, and low magnesium levels. Therefore, take PH Plus D Capsule only for the duration advised by your doctor. If you are on long-term treatment, regular monitoring is advised.
  • Consult the doctor if you are pregnant or breastfeeding. PH Plus D Capsule is not recommended for children as safety and effectiveness have not been established.
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products, to prevent any interactions.

Drug-Drug Interactions

verifiedApollotooltip
PantoprazoleRilpivirine
Critical
DomperidoneNefazodone
Severe

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
How does the drug interact with PH Plus D Capsule:
Co-administration of Rilpivirine is taken with PH Plus D Capsule, can decrease the absorption and blood levels of Rilpivirine and make the medication less effective.

How to manage the interaction:
Taking PH Plus D Capsule with Rilpivirine can lead to an interaction, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with PH Plus D Capsule:
Coadministration of PH Plus D Capsule with Nefazodone can increase the blood levels of PH Plus D Capsule.

How to manage the interaction:
There may be a possibility of interaction between PH Plus D Capsule and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneCisapride
Severe
How does the drug interact with PH Plus D Capsule:
Coadministration of PH Plus D Capsule with Cisapride can increase the blood levels of PH Plus D Capsule.

How to manage the interaction:
There may be a possibility of interaction between PH Plus D Capsule and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneCitalopram
Severe
How does the drug interact with PH Plus D Capsule:
Coadministration of PH Plus D Capsule with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking PH Plus D Capsule and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with PH Plus D Capsule:
Coadministration of PH Plus D Capsule with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking PH Plus D Capsule and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneRitonavir
Severe
How does the drug interact with PH Plus D Capsule:
Coadministration of PH Plus D Capsule with Ritonavir can increase the blood levels of PH Plus D Capsule.

How to manage the interaction:
There may be a possibility of interaction between PH Plus D Capsule and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneClarithromycin
Severe
How does the drug interact with PH Plus D Capsule:
Coadministration of PH Plus D Capsule with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between PH Plus D Capsule and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
DomperidoneKetoconazole
Severe
How does the drug interact with PH Plus D Capsule:
Coadministration of PH Plus D Capsule with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking PH Plus D Capsule and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMethadone
Severe
How does the drug interact with PH Plus D Capsule:
Coadministration of PH Plus D Capsule with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking PH Plus D Capsule and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMizolastine
Severe
How does the drug interact with PH Plus D Capsule:
Combining Mizolastine with PH Plus D Capsule can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking PH Plus D Capsule and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows; one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the level of production of stomach acid, leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), which prevents the backflow of the stomach acid back into the food pipe.
  • Include high fibre-containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidants, calcium and vitamin B12 that can help cope with the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help prevent excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H pylori infection.
  • Avoid sitting continuously, as it can increase stomach acid production. Take a break of 5 minutes in 1 hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

PH Plus D Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is best to avoid alcohol while taking medication.

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Pregnancy

Caution

If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine. You should use this medicine only if your doctor considers the benefit for you greater than the potential risk for your unborn child or baby.

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Breast Feeding

Caution

PH Plus D Capsule should be used in breastfeeding mothers only if the benefits outweigh the risks.

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Driving

Caution

Drive only if you are physically stable and mentally focussed, If you experience drowsiness after taking PH Plus D Capsule you should not drive or operate any machinery or vehicles.

bannner image

Liver

Caution

In patients with severe liver impairment, the liver enzymes should be monitored regularly during treatment with pantoprazole, particularly on long-term use

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Kidney

Caution

Inform your doctor before receiving the PH Plus D Capsule if you have a kidney impairment/disorder. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

PH Plus D Capsule is not recommended for children as safety and effectiveness have not been established.

Have a query?

FAQs

PH Plus D Capsule is used to treat Gastroesophageal reflux disease (GERD), Heartburn due to hyperacidity, Inflammation of food pipe (esophagitis), and Peptic ulcer.

Domperidone works by increasing the movement of food through the stomach and the digestive tract more quickly and, in this way, reduces the feeling of bloating, fullness and indigestion. On the other hand, it effectively blocks the action of a vomiting centre (chemoreceptor trigger zone - CTZ) located in your brain, which is responsible for inducing the feeling of nausea and vomiting. Pantoprazole helps in reducing stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall and is responsible for the release of gastric acid, damaging tissues in the food pipe, stomach, and duodenum.

PH Plus D Capsule can be safely taken as long as your doctor has prescribed it to you.

Yes, taking PH Plus D Capsule for a very long time can cause calcium depletion in the body, leading to weakening of bones. Hence, a calcium and vitamin D supplement is recommended along with PH Plus D Capsule to replenish calcium depletion in the body.

Yes. PH Plus D Capsule can alter certain medical tests, such as those for neuroendocrine tumours (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So, before undergoing such diagnostic tests, contact your doctor.

Prolonged intake of PH Plus D Capsule may weaken your bones and lower your haemoglobin level. Your doctor may prescribe you Vitamin B12 to enhance haemoglobin and calcium/vitamin D/magnesium supplements for bone health.

A combination of pantoprazole and domperidone is effective and safe.

No, PH Plus D Capsule is a prescribed drug with minimal side effects. Only take it if your doctor has recommended it to you for acidity.

PH Plus D Capsule is an antacid medicine containing Domperidone (anti-emetic) and Pantoprazole (proton pump inhibitor). It is used to treat acidity-related conditions.

Yes, PH Plus D Capsule is safe for use if taken in the dose and duration prescribed by the doctor.

Do not take PH Plus D Capsule if you are allergic to any of its components. It should be used with caution in patients with liver or kidney disease.

Dry mouth could be a side-effect of PH Plus D Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

PH Plus D Capsule may cause diarrhoea as a side effect. Drink enough fluids and eat fibre-rich food if you experience diarrhoea. Consult the doctor if the diarrhoea persists or worsens.

Store PH Plus D Capsule at room temperature, in a dry place. Keep out of sight and reach of children.

Foods/drinks that aggravate acidity like fried or spicy food, butter, oil, beverages containing caffeine, citrus fruits and alcohol should be avoided.

Alcohol may not affect PH Plus D Capsule . However, it might increase acid production. Therefore, avoid alcohol consumption.

Do not discontinue PH Plus D Capsule without consulting your doctor. To treat your condition effectively, keep taking PH Plus D Capsule for the prescribed duration.

Country of origin

INDIA

Manufacturer/Marketer address

Galpha Laboratories Limited, 221, Kanakia Zillion, E Wing, Bandra Kurla Complex Annexe, LBS Marg & CST Road Junction, Kurla West, Mumbai-400070.
Other Info - PHP0001

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Aug 5, 2025 | 11:57 AM IST

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Reference

  1. https://www.krishlarpharma.com/product/kritzol-d/
  2. https://www.zuventus.com/sites/default/files/2024-09/Pansa%20D%20PIL.pdf
  3. https://www.quest.com.np/wp-content/uploads/2024/01/Patient-Information-Leaflet-of-QPDOM.pdf
  4. https://www.ciplamed.com/product-index/pansec-dsr-capsules-0

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