Piokind M 15 Tablet belongs to the group of medicines called anti-diabetic drugs used to treat type 2 diabetes. Type 2 diabetes mellitus used to be known as 'non-insulin-dependent diabetes mellitus (NIDDM)' or 'maturity-onset diabetes'. Type 2 diabetes develops if the body does not produce enough insulin or when the insulin that your body makes does not work as well as it should. It can also develop if the body produces too much glucagon. Insulin is a substance that helps to lower the level of sugar in your blood, especially after meals.

Piokind M 15 Tablet contains Pioglitazone (thiazolidinediones) & Metformin (biguanides). Pioglitazone decreases blood sugar and reverses the effects of Type II diabetes by activating switches (PPAR) inside cells to take up free glucose from the blood and decrease its levels in the blood. Metformin, on the other hand, decreases blood sugar by decreasing its formation and increasing its consumption by cells, thereby decreasing high blood sugar levels. Piokind M 15 Tablet is used in adults to treat type 2 (non-insulin-dependent) diabetes mellitus when treatment with metformin alone is not sufficient.

Piokind M 15 Tablet should be taken with food to avoid an upset stomach. Piokind M 15 Tablet should be taken at the same time of the day each time for best results. For better advice, your doctor will decide what dose should be taken, and it can change timely depending upon your condition. Some people may have stomach aches, feeling sick (Nausea), vomiting, diarrhoea, loss of appetite, localized swelling (oedema), weight gain, headache, respiratory infection, numbness, taste disturbance, etc. Most of these side effects of Piokind M 15 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Piokind M 15 Tablet should not be stopped even if you feel better, without consulting your doctor as your sugar level keeps changing. If you stop taking Piokind M 15 Tablet abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Piokind M 15 Tablet should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have any heart disease, are or are planning to get pregnant or are breastfeeding.

Piokind M 15 Tablet lowers blood sugar in type II diabetic patients (Non-insulin dependent ) & prevents diseases of the heart, kidneys, eyes & blood vessels in feet, which happens due to persistently high levels of blood sugar in diabetic patients. Piokind M 15 Tablet plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing. Piokind M 15 Tablet lowers blood sugar due to the activation of cell switches (PPAR) to take up free glucose from blood & use it for energy production  & decrease the production of glucose inside the liver.

Piokind M 15 Tablet should not be used in patients with type 1 diabetes or with diabetic ketoacidosis. Some diabetic patients, while taking Piokind M 15 Tablet , might develop a rare but serious condition called lactic acidosis. In this condition, too much lactic acid accumulates in the blood, which can damage the workings of the liver and kidneys required for the elimination of excess lactic acid from the blood. Before you start taking Piokind M 15 Tablet , tell your doctor if you’ve ever had pancreatitis (inflammation of the pancreas), kidney disease, and low vitamin B12 levels. Piokind M 15 Tablet , when used with insulin, may extremely lower the blood sugar level, leading to hypoglycemia condition, which can be fatal. In this case, your doctor may adjust the dose by lowering the dose of insulin or Piokind M 15 Tablet . Prolonged intake of Piokind M 15 Tablet may lower your thyroid-stimulating hormone (TSH); hence, an annual check-up of TSH is recommended. In rare cases, you may also develop a serious skin reaction known as bullous pemphigoid that requires immediate medical attention. Tell your doctor if you are going to have a diagnostic test with an injection of dye or X-ray contrast agent. The use of Piokind M 15 Tablet should be stopped for a short time before having an X-ray procedure.