Pregasule-25 Capsule 10's
MRP ₹77.5
(Inclusive of all Taxes)
₹11.6 Cashback (15%)
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About Pregasule-25 Capsule
Pregasule-25 Capsule belongs to a group of medications called anticonvulsants, primarily used for the prevention of neuropathic pain, epilepsy (seizure episodes), and fibromyalgia (musculoskeletal pain). Neuropathic pain is chronic nerve pain usually caused by damaged nerves due to conditions such as diabetes, shingles (a viral infection that causes a painful rash), spinal cord injury, or injuries to tissue, muscles, or joints.
Pregasule-25 Capsule contains pregabalin, which works by calming damaged or overactive nerves in the body that can cause nerve or musculoskeletal pain or seizures. In addition, it decreases the number of pain signals sent out by damaged nerves.
You should take Pregasule-25 Capsule for as long as your doctor has prescribed it, based on your medical condition. You may experience certain common side effects, such as dizziness, somnolence (sleepiness or drowsiness), dry mouth, oedema (fluid build-up with swelling), blurred vision, weight gain, and abnormal thinking (difficulty with concentration or attention). Most of these side effects do not require medical attention. However, if they persist or worsen, consult your doctor.
Before taking Pregasule-25 Capsule , inform your doctor if you are allergic to any of its ingredients. Tell your doctor if you experience any symptoms of suicidal thoughts or behaviour while taking Pregasule-25 Capsule . Also, inform your doctor if you have a history of alcohol or drug addiction, mood disorders, bleeding disorders, chronic obstructive pulmonary disease (COPD), diabetes, or kidney, liver, or heart disease. Pregasule-25 Capsule is not recommended during pregnancy or breastfeeding unless specifically advised by your doctor. It should not be given to children under 18 years of age, as its safety and effectiveness have not been established in this age group.
Uses of Pregasule-25 Capsule
Pregasule-25 Capsule is used in the treatment of Neuropathic pain, Epilepsy (seizures/fits) and Fibromyalgia (musculoskeletal pain). The detailed uses of Pregasule-25 Capsule are as follows:
- Neuropathic Pain Relief: Pregasule-25 Capsule is frequently recommended to treat nerve pain caused by conditions like postherpetic neuralgia, diabetic neuropathy, or spinal cord injury.
- Epilepsy management: It helps regulate seizure activity and can be used as an adjuvant therapy for people with partial seizures.
- Fibromyalgia Treatment: It could enhance the general quality of life by reducing the pervasive pain and suffering brought on by fibromyalgia.
- Generalised Anxiety Disorder (GAD): Pregasule-25 Capsule reduces excessive worry and relaxes the nervous system to treat anxiety problems.
- Post-Traumatic Stress Disorder (PTSD): In order to help manage the symptoms of Post-Traumatic Stress Disorder (PTSD), Pregasule-25 Capsule can be administered to relieve anxiety and related conditions.
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Directions for Use
- Pregasule-25 Capsule can be taken with or without food, as advised by your doctor.
- Your doctor will determine the dosage and timing of this medication based on your medical condition.
- Swallow Pregasule-25 Capsule as a whole with a glass of water.
- Do not crush, chew, break, or open it.
Key Benefits
Pregasule-25 Capsule belongs to a group of medications called anticonvulsants, which are used to prevent neuropathic pain (pain caused by damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (characterised by seizures or fits). It contains pregabalin, which works by calming damaged or overactive nerves in the body that can cause nerve or musculoskeletal pain or seizures. Additionally, it reduces the number of pain signals transmitted by damaged nerves.
How Pregasule-25 Capsule Works
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- Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
- Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
- When standing up, do so slowly and carefully to avoid sudden dizziness.
- Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
- Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
- If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
- Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
- Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
- Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
- Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
- Gently massage the swollen area with firm but not painful pressure.
- Keep the swollen area clean and moisturized to prevent injury and infection.
- Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
- If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
- Confusion is a major psychotic disorder that needs immediate medical attention.
- Acknowledge your experience and put effort to control confusion.
- Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
- Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
- Talk to your dietician and consume food that can improve your mental health.
- Blood flow to the brain and the rest of the body is increased by physical activity. This could help you maintain your memory.
- Reading, solving puzzles, and picking up new skills are examples of mental workouts that can keep the brain engaged and enhance memory retention.
- Maintaining an active social life enhances memory and brain stimulation.
- Relaxation methods like yoga, meditation, and deep breathing can help because long-term stress can affect memory.
- Drink plenty of water and stay hydrated.
- Limit the intake of alcohol and caffeine.
- Maintain good hygiene habits.
- Avoid holding on and empty the bladder at regular intervals.
- Try to quit smoking.
What if I have taken an overdose of Pregasule-25 Capsule
Drug Warnings
Do not take Pregasule-25 Capsule if you are known to be allergic to any of its ingredients. Do not stop taking Pregasule-25 Capsule without consulting your doctor, as this may cause withdrawal symptoms. Inform your doctor if you experience any symptoms of suicidal thoughts or behaviour while taking Pregasule-25 Capsule . Also, let your doctor know if you have a history of alcohol or drug addiction, mood disorders, bleeding disorders, chronic obstructive pulmonary disease (COPD), diabetes, or kidney, liver, or heart disease before starting Pregasule-25 Capsule . Pregasule-25 Capsule is not recommended during pregnancy or breastfeeding unless specifically advised by your doctor. It should not be given to children under 18 years of age, as its safety and effectiveness have not been established in this age group. Pregasule-25 Capsule may cause decreased concentration, drowsiness, and dizziness, so avoid driving or operating machinery unless you are fully alert. Avoid consuming alcohol while taking Pregasule-25 Capsule , as it may worsen side effects such as dizziness and drowsiness.
Drug-Drug Interactions
Drug-Drug Interactions
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Using Pregasule-25 Capsule together with Codeine may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Although taking Codeine and Pregasule-25 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
Using Pregasule-25 Capsule together with Oxycodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).
How to manage the interaction:
Although taking oxycodone and Pregasule-25 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
Using Pregasule-25 Capsule together with Hydromorphone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Although taking Hydromorphone and Pregasule-25 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
Using Tapentadol together with Pregasule-25 Capsule may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Taking Pregasule-25 Capsule with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without consulting a doctor.
When Tramadol is used with Pregasule-25 Capsule, it may possibly lead to side effects such as respiratory difficulties, unconsciousness.
How to manage the interaction:
Although taking tramadol and Pregasule-25 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
Using Pregasule-25 Capsule together with Alfentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).
How to manage the interaction:
Although taking Pregasule-25 Capsule and Alfentanil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
Using Pregasule-25 Capsule together with Dezocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).
How to manage the interaction:
Although taking Dezocine and Pregasule-25 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
Using Pregasule-25 Capsule together with Remifentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).
How to manage the interaction:
Although taking remifentanil and Pregasule-25 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
Taking Ketamine with Pregasule-25 Capsule may increase the risk of side effects.
How to manage the interaction:
Although taking Pregasule-25 Capsule and ketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as dizziness, drowsiness, confusion, difficulty concentrating, breathing difficulty, consult the doctor. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
Using Pregasule-25 Capsule together with Methadone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Although taking methadone and Pregasule-25 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
Drug-Food Interactions
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St. John’S Wort
How to manage the interaction:
Taking St. John's wort during Pregasule-25 Capsule treatment may increase the risk of side effects such as dizziness, drowsiness, confusion, and difficulty concentrating, impairment in thinking, judgment, and motor coordination. Avoid St. John's wort during treatment with Pregasule-25 Capsule.
Diet & Lifestyle Advise
- Maintain a diet rich in fruits, vegetables, whole grains, and omega-3-rich foods.
- Avoid fried foods, high-fat dairy products, pastries, and processed foods, as they may worsen neuropathic pain.
- Include cayenne pepper in your diet, as it can help reduce neuropathic pain.
- Exercising regularly helps maintain weight and improve overall health.
- Rest well; get plenty of sleep.
- Avoid smoking and alcohol consumption.
- Meditation and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
- Have a seizure response plan that helps those around you know what to do.
- Prepare your living area; small changes may help reduce the risk of physical injury during a seizure.
- Install an alarm or emergency device to get assistance during a seizure attack.
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Alcohol
Safe if prescribed
Avoid consuming alcohol while taking Pregasule-25 Capsule , as it may worsen the side effects like dizziness and drowsiness.
Pregnancy
Consult your doctor
Pregasule-25 Capsule is a category C pregnancy drug. Please consult your doctor if you are pregnant before starting Pregasule-25 Capsule . Your doctor will weigh the benefits and potential risks before prescribing Pregasule-25 Capsule .
Breast Feeding
Consult your doctor
Pregasule-25 Capsule should not be used during breastfeeding unless prescribed by a doctor. Your doctor will weigh the benefits and potential risks before prescribing Pregasule-25 Capsule .
Driving
Safe if prescribed
Pregasule-25 Capsule may cause decreased concentration, drowsiness, and dizziness; therefore, avoid driving or operating machinery unless you are fully alert.
Liver
Consult your doctor
Take Pregasule-25 Capsule with caution, especially if you have or had a history of liver disease/conditions. The dose may be adjusted by your doctor as required.
Kidney
Consult your doctor
Take Pregasule-25 Capsule with caution, especially if you have or had a history of kidney disease/conditions. The dose may be adjusted by your doctor as required.
Children
Safe if prescribed
Pregasule-25 Capsule is not recommended for children below the age of 18 years, as its safety and effectiveness have not been established in this age group.
Heart
Please consult your doctor before using Pregasule-25 Capsule if you have pre-existing heart problems. Your doctor will prescribe Pregasule-25 Capsule if the benefits outweigh the risks.
Geriatrics
Consult your doctor
Please consult a doctor before giving Pregasule-25 Capsule to geriatric patients. Your doctor will prescribe Pregasule-25 Capsule if the benefits outweigh the risks.
FAQs
Pregasule-25 Capsule belongs to a group of medications called "anticonvulsants", primarily used in the prevention of neuropathic pain, epilepsy (seizure episodes), and fibromyalgia (musculoskeletal pain).
Pregasule-25 Capsule contains Pregabalin, which works by calming the damaged or overactive nerves in the body that may cause nerve or musculoskeletal pain or seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body.
Yes, Pregasule-25 Capsule may cause weight gain because it increases your hunger. However, regular physical exercise and a balanced diet with low-calorie food may help you keep your weight stable. Please consult your doctor if you have any further concerns about keeping your weight stable.
No, you are not recommended to take Pregasule-25 Capsule with tramadol, as co-administration of these medicines may cause breathing problems, drowsiness, and even lead to a state of coma. So, before using Pregasule-25 Capsule with painkillers like oxycodone or any other opioid analgesics, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.
No, Pregasule-25 Capsule is not a normal painkiller. It is an anticonvulsant that helps treat neuropathic pain, musculoskeletal pain, and epilepsy (seizures).
Do not discontinue Pregasule-25 Capsule without consulting your doctor, as it might cause withdrawal symptoms. The doctor will reduce the dose gradually to prevent withdrawal symptoms.
Neuropathic pain occurs due to nerve damage while muscle pain occurs due to spasms or injury. Neuropathic pain is chronic and is felt as tingling and burning sensation. Whereas, muscle pain is a dull ache and will generally get better within a few days unless it is a severe injury.
Pregasule-25 Capsule works in different ways for each disease. For neuropathic and musculoskeletal pain, it calms the damaged or overactive nerves and decreases pain signals sent out by damaged nerves in the body. In case of epilepsy, it reduces abnormal electrical activity in the brain.
Pregasule-25 Capsule starts working within a week and you may notice its full benefits in a few weeks. Continue taking Pregasule-25 Capsule for the prescribed duration for effective results.
Pregasule-25 Capsule should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.
Pregasule-25 Capsule may be addictive. Therefore, take Pregasule-25 Capsule only for the prescribed duration. Do not take Pregasule-25 Capsule for a prolonged time as it may lead to mental or physical dependence.
Taking Pregasule-25 Capsule with diazepam may increase side effects such as dizziness, confusion, drowsiness and difficulty concentrating. Hence, consult the doctor before taking diazepam with Pregasule-25 Capsule .
Pregasule-25 Capsule may cause common side effects, such as dizziness, somnolence (sleepiness/drowsiness), dry mouth, oedema (fluid overload with swelling), blurred vision, weight gain, and abnormal thinking (difficulty with concentration/attention). Most of these side effects do not require medical attention and will gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
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Reference
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021446s035,022488s013lbl.pdf
- https://www.medicines.org.uk/emc/product/1761/pil
- https://www.drugs.com/pregabalin.html
- https://medlineplus.gov/druginfo/meds/a605045.html
- https://www.nhs.uk/medicines/pregabalin/
- https://www.ema.europa.eu/en/documents/product-information/pregabalin-sandoz-epar-product-information_en.pdf
