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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pregeb 75 Capsule is used in the prevention of neuropathic pain, epilepsy (seizure episodes), fibromyalgia (musculoskeletal pain), and neuralgia (pain due to damaged/irritated nerve). It contains Pregabalin, which works by calming the damaged or overactive nerves in the body that may cause nerve or musculoskeletal pain or seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body. It may cause side efffects such as dizziness, somnolence (sleepiness/drowsiness), dry mouth, oedema (fluid overload with swelling), blurred vision, weight gain and abnormal thinking (difficulty with concentration/attention). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

PREGABALIN-75MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pregeb 75 Capsule

Pregeb 75 Capsule belongs to a group of medications called 'anti-convulsants', primarily used in the prevention of neuropathic pain, epilepsy (seizure episodes), fibromyalgia (musculoskeletal pain), and neuralgia (pain due to damaged/irritated nerve). Neuropathic pain is chronic nerve pain usually caused by damaged nerves due to a variety of diseases like diabetes, shingles (viral infection that causes a painful rash), spinal cord injury, and injuries to tissue, muscles, or joints.

Pregeb 75 Capsule contains 'Pregabalin', which works by calming the damaged or overactive nerves in the body that may cause nerve or musculoskeletal pain or seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body.

In some cases, Pregeb 75 Capsule might cause side effects like dizziness, somnolence (sleepiness/drowsiness), dry mouth, oedema (fluid overload with swelling), blurred vision, weight gain and abnormal thinking (difficulty with concentration/attention). Most of these side effects do not require medical attention. However, if the side effects persist or worsen, consult a doctor.

Tell your doctor if you are facing symptoms of suicidal ideation or behaviour, drug addiction, chronic pulmonary insufficiency, muscle pain, soreness, weakness, kidney, liver, or heart diseases.  Caution is required before giving Pregeb 75 Capsule to pregnant or breastfeeding women. The safety and effectiveness in children less than 18 years of age have not been established, so Pregeb 75 Capsule should not be given to them.

Uses of Pregeb 75 Capsule

Pregeb 75 Capsule is used in the treatment of Neuropathic pain, Epilepsy (seizures/fits) and Fibromyalgia (musculoskeletal pain). The detailed uses of Pregeb 75 Capsule are as follows:
• Neuropathic Pain Relief: Pregeb 75 Capsule is frequently recommended to treat nerve pain caused by conditions like postherpetic neuralgia or diabetes.
• Epilepsy management: It helps regulate seizure activity and can be used as an adjuvant therapy for people with partial seizures.
• Generalized Anxiety Disorder (GAD): Pregeb 75 Capsule reduces excessive worry and relaxes the nervous system to treat anxiety problems.
• Fibromyalgia Treatment: It could enhance general quality of life by reducing the pervasive pain and suffering brought on by fibromyalgia.
• Post-Traumatic Stress Disorder (PTSD): In order to help manage the symptoms of Post-Traumatic Stress Disorder (PTSD), Pregeb 75 Capsule can be administered to relieve anxiety and related conditions.

Directions for Use

Tablet/capsule: Swallow it as a whole with a glass of water. Do not crush, chew, or break it. Oral solution/Syrup: Shake the bottle well before use. Take the prescribed dose with the help of a measuring cup/dosing syringe/dropper.

Medicinal Benefits

Pregeb 75 Capsule belongs to a group of medications called 'anticonvulsants' used to prevent neuropathic pain (pain due to damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (fits). It works by calming the damaged or overactive nerves in the body that may cause pain or seizures, thereby decreasing the number of pain signals sent out by damaged nerves in the body.

How Pregeb 75 Capsule Works

Pregeb 75 Capsule contains 'Pregabalin', which works by calming the damaged or overactive nerves in the body that may cause nerve or musculoskeletal pain or seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body.

Storage

Store in a cool and dry place away from sunlight
Side effects of Pregeb 75 Capsule
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Blood flow to the brain and the rest of the body is increased by physical activity. This could help you maintain your memory.
  • Reading, solving puzzles, and picking up new skills are examples of mental workouts that can keep the brain engaged and enhance memory retention.
  • Maintaining an active social life enhances memory and brain stimulation.
  • Relaxation methods like yoga, meditation, and deep breathing can help because long-term stress can affect memory.
  • Drink plenty of water and stay hydrated.
  • Limit the intake of alcohol and caffeine.
  • Maintain good hygiene habits.
  • Avoid holding on and empty the bladder at regular intervals.
  • Try to quit smoking.
  • Perform balance exercises like heel raises, standing on one leg, and weight shifts with the guidance of a physical therapist.
  • Focus on strengthening leg muscles and core muscles for better stability.
  • Stay hydrated by drinking plenty of water as dehydration may lead to unsteadiness and dizziness.
  • Wear low-heeled shoes with good tread for better grip.
  • Change your surroundings by removing tripping hazards like clutter, loose rugs and poorly lit areas.
  • Avoid sudden position changes; stand up slowly and take your time to move around.
  • Watch out for rapid head movements that might trigger dizziness.
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.

What if I have taken an overdose of Pregeb 75 Capsule

Do not take more than the prescribed dose of Pregeb 75 Capsule as it may cause overdose. The symptoms of overdose include sleepiness, confusion,agitation, restlessness, fits and coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Pregeb 75 Capsule if you are known to be allergic to any of its contents. Inform your doctor if you have symptoms of suicidal ideation or behaviour, drug addiction, chronic lung diseases, muscle weakness, heart problems, liver/kidney impairment. Caution is required before giving Pregeb 75 Capsule to pregnant or breastfeeding women. The safety and effectiveness of Pregeb 75 Capsule in children under 18 years of age have not been established, so Pregeb 75 Capsule should not be given to them. Taking Pregeb 75 Capsule with opioids analgesics or painkillers like oxycodone can cause respiratory failure, coma, and even leading to death, so avoid its intake together. If you are taking any sleeping pills or tranquillizers, tell your doctor about this as Pregeb 75 Capsule interacts with these drugs and causes sleepiness, drowsiness and dizziness and affects your daily activity. Immediately contact a doctor if you have swelling of your face, mouth, tongue, lips, gums, neck, or throat (angioedema).

Drug-Drug Interactions

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PregabalinAlfentanil
Severe
PregabalinPethidine
Severe

Drug-Drug Interactions

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PregabalinAlfentanil
Severe
How does the drug interact with Pregeb 75 Capsule:
Using Pregeb 75 Capsule together with Alfentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Pregeb 75 Capsule and Alfentanil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinPethidine
Severe
How does the drug interact with Pregeb 75 Capsule:
Using Pregeb 75 Capsule together with Pethidine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pethidine and Pregeb 75 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinKetamine
Severe
How does the drug interact with Pregeb 75 Capsule:
Taking Ketamine with Pregeb 75 Capsule may increase the risk of side effects.

How to manage the interaction:
Although taking Pregeb 75 Capsule and ketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as dizziness, drowsiness, confusion, difficulty concentrating, breathing difficulty, consult the doctor. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinDezocine
Severe
How does the drug interact with Pregeb 75 Capsule:
Using Pregeb 75 Capsule together with Dezocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Dezocine and Pregeb 75 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinFentanyl
Severe
How does the drug interact with Pregeb 75 Capsule:
Using Pregeb 75 Capsule together with Fentanyl can increase the risk of side effects.

How to manage the interaction:
Although taking fentanyl together with Pregeb 75 Capsule can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you have dizziness, sleepiness, difficulty concentrating, or impairment in judgment. Do not stop taking any medication without consulting a doctor.
PregabalinNalbuphine
Severe
How does the drug interact with Pregeb 75 Capsule:
Using Pregeb 75 Capsule together with Nalbuphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Nalbuphine and Pregeb 75 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinRemifentanil
Severe
How does the drug interact with Pregeb 75 Capsule:
Using Pregeb 75 Capsule together with Remifentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking remifentanil and Pregeb 75 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinHydrocodone
Severe
How does the drug interact with Pregeb 75 Capsule:
Using Pregeb 75 Capsule together with Hydrocodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydrocodone and Pregeb 75 Capsule together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinHydromorphone
Severe
How does the drug interact with Pregeb 75 Capsule:
Using Pregeb 75 Capsule together with Hydromorphone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydromorphone and Pregeb 75 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinPentazocine
Severe
How does the drug interact with Pregeb 75 Capsule:
Using Pregeb 75 Capsule together with Pentazocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pentazocine and Pregeb 75 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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PREGABALIN-75MGHerbal products/medicines
Moderate

Drug-Food Interactions

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PREGABALIN-75MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Taking St. John's wort during Pregeb 75 Capsule treatment may increase the risk of side effects such as dizziness, drowsiness, confusion, and difficulty concentrating, impairment in thinking, judgment, and motor coordination. Avoid St. John's wort during treatment with Pregeb 75 Capsule.

Diet & Lifestyle Advise

  • Maintain a diet rich in fruits, vegetables, whole grains, omega-3 rich foods. Avoid fried foods, high-fat dairy products, pastries, and processed foods, as they may worsen neuropathic pain.

  • Do regular exercise and maintain a healthy weight.

  • Avoid the consumption of alcohol as it may increase dizziness or drowsiness.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects like dizziness and sleepiness.

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Pregnancy

Caution

Pregeb 75 Capsule is a category C pregnancy drug. Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing Pregeb 75 Capsule .

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Breast Feeding

Caution

Pregeb 75 Capsule should be used in breastfeeding women only when prescribed by a doctor. Your doctor will weigh the benefits and potential risks before prescribing Pregeb 75 Capsule .

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Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using Pregeb 75 Capsule . Pregeb 75 Capsule can also sometimes cause blurry/double vision; hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Take Pregeb 75 Capsule with caution, especially if you have or had a history of liver disease/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Pregeb 75 Capsule with caution, especially if you have or had a history of kidney disease/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Pregeb 75 Capsule is not recommended for children below the age of 18 years. The safety and efficacy of Pregeb 75 Capsule have not been established.

FAQs

Pregeb 75 Capsule is primarily used in the prevention of neuropathic pain, epilepsy (seizure episodes), fibromyalgia (musculoskeletal pain), and neuralgia (pain due to damaged/irritated nerve).

Pregeb 75 Capsule works by blocking the pain centre that interferes with pain messages that travel through the brain and spine (central nervous system). In epilepsy, it prevents episodes of fits by reducing the abnormal electrical activity in the brain and calming the overactive nerves.

Yes, Pregeb 75 Capsule may cause weight gain because it increases your hunger. However, regular physical exercise and a balanced diet with low-calorie food may help you keep your weight stable. Please consult the doctor if you have any further concerns about keeping your weight stable.

No, you are not recommended to take Pregeb 75 Capsule with tramadol as co-administration of these medicines may cause breathing problems, drowsiness, and even lead to a stage of coma. So, before using Pregeb 75 Capsule with painkillers like oxycodone or any other opioid analgesics, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.

No, Pregeb 75 Capsule is not a normal painkiller. It is an anti-convulsant that helps treat neuropathic pain, musculoskeletal pain, and epilepsy.

Do not discontinue Pregeb 75 Capsule without consulting your doctor as it might cause withdrawal symptoms. The doctor will reduce the dose gradually to prevent withdrawal symptoms.

Neuropathic pain occurs due to nerve damage while muscle pain occurs due to spasms or injury. Neuropathic pain is chronic and is felt as tingling and burning sensation. Whereas, muscle pain is a dull ache and will generally get better within a few days unless it is a severe injury.

Pregeb 75 Capsule works in different ways for each disease. For neuropathic and musculoskeletal pain, it calms the damaged or overactive nerves and decreases pain signals sent out by damaged nerves in the body. In case of epilepsy, it reduces abnormal electrical activity in the brain.

Pregeb 75 Capsule starts working within a week and you may notice its full benefits in a few weeks. Continue taking Pregeb 75 Capsule for the prescribed duration for effective results.

Pregeb 75 Capsule should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.

Pregeb 75 Capsule may be addictive. Therefore, take Pregeb 75 Capsule only for the prescribed duration. Do not take Pregeb 75 Capsule for a prolonged time as it may lead to mental or physical dependence.

Taking Pregeb 75 Capsule with diazepam may increase side effects such as dizziness, confusion, drowsiness and difficulty concentrating. Hence, consult the doctor before taking diazepam with Pregeb 75 Capsule .

Pregeb 75 Capsule may cause side effects like dizziness, somnolence (sleepiness/drowsiness), dry mouth, oedema (fluid overload with swelling), blurred vision, weight gain and abnormal thinking (difficulty with concentration/attention). Most of these side effects do not require medical attention. However, if the side effects persist or worsen, consult a doctor.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - PRE0015

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