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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Psorid 100 Capsule is used to prevent organ transplant rejection. It is also used to treat inflammation and pain associated with psoriasis and rheumatoid arthritis. This medicine contains cyclosporine, which works by suppressing the immune system. It also helps reduce rapid skin cell growth, pain, and inflammation. It may sometimes cause common side effects such as headaches, vomiting, nausea, loss of appetite, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

CYCLOSPORINE-100MG

Manufacturer/Marketer :

Biocon Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

NPPA :

Regulated

About Psorid 100 Capsule

Psorid 100 Capsule belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ rejection after a transplant. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis.

Psorid 100 Capsule contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and lowers pain and inflammation in the joints.

Psorid 100 Capsule may cause side effects like headaches, vomiting, nausea, loss of appetite and diarrhoea. Most of these side effects do not require medical attention and resolve over time. However, consult your doctor if the side effects persist or worsen.

To treat your condition effectually, continue taking Psorid 100 Capsule for as long as your doctor has prescribed. Inform your doctor about your health condition and any medications you are taking to help rule out any potential/unpleasant side effects.

Uses of Psorid 100 Capsule

Psorid 100 Capsule is used to prevent organ rejection and treat psoriasis and rheumatoid arthritis. The detailed uses of Psorid 100 Capsule are as follows:

  • Treatment of Organ Transplant Rejection: Psorid 100 Capsule is used in the prevention of organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants.
  • Treatment of Psoriasis: Psorid 100 Capsule is used in the treatment of psoriasis. It helps reduce rapid skin cell growth and inflammation caused by psoriasis.
  • Treatment of Rheumatoid Arthritis: Psorid 100 Capsule is used in the treatment of rheumatoid arthritis. It helps reduce pain and inflammation in the joints and slows down joint damage.

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Directions for Use

  • Psorid 100 Capsule can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Check the label for directions and use as advised by your doctor.
  • Measure the prescribed dose of Psorid 100 Capsule using the dosing syringe. Mix it with apple or orange juice, stir well, and drink immediately.
  • Do not store the prepared mixture for later use.

Key Benefits

  • Psorid 100 Capsule suppresses the immune system to prevent the rejection of transplanted organs (e.g., kidney, liver, heart).
  • It is also used in bone marrow and stem cell transplantation to prevent graft rejection.
  • Psorid 100 Capsule helps control immune overactivity in various autoimmune conditions by blocking immune cells that attack the body’s own tissues.
  • It reduces rapid skin cell growth and inflammation in severe psoriasis, leading to clearer skin and symptom relief.
  • This medicine reduces joint pain, inflammation, and slows down joint damage in patients with active rheumatoid arthritis unresponsive to other therapies.
  • It may also be used to treat severe atopic dermatitis, especially in patients who do not respond adequately to topical treatments.
  • Helps manage severe inflammatory eye diseases that can threaten vision by reducing immune-mediated damage.
  • It is used in certain cases of nephrotic syndrome (a kidney disorder causing excess protein loss in urine), especially when other treatments fail.

How Psorid 100 Capsule Works

Psorid 100 Capsule contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and the production of interleukins (molecules involved in inflammation). Additionally, it also reduces pain and inflammation in the joints and slows down the joint damage caused by an overactive immune system.

Storage

Store in a cool and dry place away from sunlight
Side effects of Psorid 100 Capsule
  • Get plenty of fresh air.
  • Take regular sips of a cold drink.
  • Take ginger containing foods like ginger tea and ginger biscuits.
  • Do not take heavy meals at a time, take small and frequent meals.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Using a cold compress may help relieve itching and inflammation associated with conjunctivitis.
  • A warm compress and washing the eyes with water can help with crusting on the eyelids.
  • Avoid wearing contact lens until you feel better; use spectacles instead.
  • Do not rub the eyes.
  • Practise good hand hygiene and avoid touching the eyes to prevent the spread of infection.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Increase protein intake by eating protein-rich foods like eggs, fish, lean meat, beans, and nuts to support nail strength.
  • Include biotin-rich foods like salmon, avocado, bananas, almonds, and whole grains in your diet to promote nail health.
  • Boost iron intake by consuming iron-rich foods like spinach, red meat, lentils, and fortified cereals to prevent iron deficiency.
  • Moisturize your nails and cuticles regularly by applying cuticle oil or hand cream multiple times a day.
  • Keep your nails short to reduce the risk of breakage and snagging.
  • Avoid biting your nails, as it can cause significant damage to your nails and cuticles.
  • Consider taking biotin supplements after consulting your doctor, as they may help strengthen brittle nails.

What if I have taken an overdose of Psorid 100 Capsule

Do not take more than the prescribed dose of Psorid 100 Capsule as it may cause an overdose. Symptoms of overdose include vomiting, drowsiness, headache, fast heartbeat, yellowing of the skin/eyes, and swelling of the arms, hands, feet, ankles, or lower legs. If you suspect you have taken an overdose or experience any of these symptoms, please consult a doctor immediately.

Drug Warnings

  • Do not take Psorid 100 Capsule if you are allergic to any of the components.
  • Let your doctor know before using Psorid 100 Capsule if you have/had liver or kidney problems, epilepsy, high blood pressure, low levels of magnesium, high levels of potassium, cancer, or infection.
  • Psorid 100 Capsule may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.
  • Before taking Psorid 100 Capsule, inform your doctor if you have any type of cancer.
  • Consult your doctor before taking Psorid 100 Capsule if you are pregnant or planning for pregnancy.
  • Psorid 100 Capsule should not be taken by breastfeeding mothers as it passes into breast milk.
  • Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Psorid 100 Capsule:
Combining Psorid 100 Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Psorid 100 Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Psorid 100 Capsule:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Psorid 100 Capsule with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
How does the drug interact with Psorid 100 Capsule:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Psorid 100 Capsule with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Psorid 100 Capsule:
Coadministration of pitavastatin with Psorid 100 Capsule may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Psorid 100 Capsule is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Psorid 100 Capsule:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Psorid 100 Capsule with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Psorid 100 Capsule:
Taking Psorid 100 Capsule with itraconazole may significantly raise blood levels of Psorid 100 Capsule.

How to manage the interaction:
Although there is a interaction between cyclosporine and itraconazole can be used if a doctor prescribes them. However, consult a doctor if you have any of the following symptoms fever, sore throat, unusual bruising or bleeding, increased or reduced urination, nausea, vomiting, diarrhea, stomach discomfort, dizziness, tiredness, headache, shaking, fits, and headache. Never stop taking any medications without talking to a doctor.
How does the drug interact with Psorid 100 Capsule:
Coadministration of posaconazole and Psorid 100 Capsule together can enhance the effects of Psorid 100 Capsule.

How to manage the interaction:
Although using posaconazole and Psorid 100 Capsule together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor immediately if you experience any symptoms such as nausea, dizziness, weakness, vomiting, diarrhea, abdominal pain, or headache. Do not stop taking any medications without consulting a doctor.
Severe
How does the drug interact with Psorid 100 Capsule:
Coadministration of iohexol with Psorid 100 Capsule may increases the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between iohexol and Psorid 100 Capsule, they can be taken together if your doctor has prescribed them. However, contact your doctor immediately if experience any symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm. Do not stop using any medications without talking to a doctor.
How does the drug interact with Psorid 100 Capsule:
Taking carbamazepine and Psorid 100 Capsule may decrease the effects of Psorid 100 Capsule.

How to manage the interaction:
Although taking carbamazepine and Psorid 100 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Psorid 100 Capsule:
Using ceritinib and Psorid 100 Capsule may increase the blood levels of Psorid 100 Capsule.

How to manage the interaction:
There may be a possibility of interaction between ceritinib and Psorid 100 Capsule, but it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience any symptoms such as diarrhea or stomach pain, feeling dizzy or tired, having a headache or fits, having a fever or sore throat, or bleeding or bruising. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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CYCLOSPORINE-100MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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CYCLOSPORINE-100MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit and grapefruit juice while taking Psorid 100 Capsule can increase the effects of Psorid 100 Capsule. Avoid consuming grapefruit and grapefruit juice while taking Psorid 100 Capsule.

Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid) such as apples, cherries, broccoli, spinach, and blueberries.
  • Consuming food rich in probiotics helps in developing the immune system against allergies.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Avoid consumption of foods with excess sugar to prevent flare-up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a regular sleep pattern would be helpful.
  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

Habit Forming

No

Therapeutic Class

[IMMUNOSUPPRESSANTS]

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Alcohol

Safe if prescribed

You are recommended to avoid alcohol consumption while taking Psorid 100 Capsule. It could lead to increased dizziness.

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Pregnancy

Consult your doctor

Psorid 100 Capsule belongs to pregnancy category C. Consult your doctor before taking Psorid 100 Capsule if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Psorid 100 Capsule passes into breast milk. Avoid breastfeeding while taking Psorid 100 Capsule.

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Driving

Safe if prescribed

Psorid 100 Capsule may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Psorid 100 Capsule is not recommended for children as efficacy and safety have not been established.

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Heart

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Consult your doctor

Psorid 100 Capsule should be given to elderly patients only if prescribed by a doctor. If you have any concerns, please consult your doctor.

FAQs

Psorid 100 Capsule is used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis.

Psorid 100 Capsule acts as an immunosuppressant, which helps in reducing inflammation and preventing joint stiffness, thereby providing relief from rheumatoid arthritis.

If you miss a dose of Psorid 100 Capsule, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose instead.

Diarrhoea might be a side effect of Psorid 100 Capsule. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Yes, the use of Psorid 100 Capsule may cause abnormal facial and body hair growth as a common side effect. Please consult your doctor if you have any concerns.

Psorid 100 Capsule is known to suppress the immune system. As a result, it increases the risk of infections and developing cancers, especially of the skin. Therefore, avoid prolonged exposure to sunlight by wearing suitable protective clothing and using sunscreen regularly.

Psorid 100 Capsule may cause high blood pressure. Therefore, consult the doctor before taking Psorid 100 Capsule if you have high blood pressure.

No, Psorid 100 Capsule is not a steroid. It is an immunosuppressant.

Psorid 100 Capsule may cause weight gain. Follow a healthy diet and exercise regularly to maintain proper weight. Consult your doctor if you have any concerns.

Psorid 100 Capsule may cause fatigue. Eat a healthy diet, get regular exercise, manage stress, improve sleep habits, and quit smoking. Doing these may help cope with fatigue.

Yes, your doctor will recommend certain tests to check your body’s response to Psorid 100 Capsule.

Psorid 100 Capsule may cause side effects like headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Talk to your doctor if you experience these side effects persistently.

Use the measuring cup/dosing syringe provided with the pack to measure the prescribed dose of Psorid 100 Capsule. Mix the solution/suspension in a glass of milk or orange juice, stir well, and consume immediately. Do not store the prepared mixture for later use.

You are advised to take Psorid 100 Capsule for the duration prescribed by the doctor. The duration of treatment will depend upon your condition and response to the treatment.

Country of origin

INDIA

Manufacturer/Marketer address

20th KM, Hosur Road, Electronic City, Bangalore, India - 560 100
Other Info - PSO0025

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