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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Qtern 5mg/10mg Tablet is used to treat type-2 diabetes mellitus adjunct to diet and exercise. It works by reducing fasting and post-prandial blood sugar levels and removing excess sugar from the body via urine. In some cases, this medicine may cause side effects such as urinary tract infection, low blood sugar, and upper respiratory tract infection. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Astra Zeneca Pharma India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Qtern 5mg/10mg Tablet

Qtern 5mg/10mg Tablet is used to treat type-2 diabetes mellitus adjunct to diet and exercise. Type-2 diabetes mellitus is also known as non-insulin-dependent diabetes or adult-onset diabetes. Qtern 5mg/10mg Tablet is not indicated to treat diabetic ketoacidosis or type-1 diabetes mellitus.
 
Qtern 5mg/10mg Tablet is a combination of two drugs: Saxagliptin (dipeptidyl peptidase-4 inhibitor) and Dapagliflozin (sodium-glucose cotransporter-2 inhibitors). Saxagliptin enhances glucose-mediated insulin secretion. Thus, it reduces fasting and post-prandial blood sugar concentrations. Dapagliflozin removes excess sugar from the body via urine. Together, Qtern 5mg/10mg Tablet helps treat type-2 diabetes mellitus.
 
You are advised to take Qtern 5mg/10mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as urinary tract infection, hypoglycaemia, upper respiratory tract infection, and dyslipidaemia. You are advised to consult your doctor if the side effects persist or worsen.
 
Avoid taking Qtern 5mg/10mg Tablet if you are pregnant or breastfeeding. Qtern 5mg/10mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established.  Avoid alcohol consumption while taking Qtern 5mg/10mg Tablet as it might cause unpleasant side effects. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of Qtern 5mg/10mg Tablet

Treatment of Type-2 diabetes mellitus.

Directions for Use

• Qtern 5mg/10mg Tablet can be taken with or without food. However, inform your doctor before taking this medication if you are on a low-sodium diet, as it may increase the risk of dehydration.• It is recommended to take Qtern 5mg/10mg Tablet once daily in the morning, or as advised by your doctor.• Swallow Qtern 5mg/10mg Tablet as a whole with a glass of water.• Do not break, chew, or crush it.

Medicinal Benefits

Qtern 5mg/10mg Tablet is a combination of two drugs: Saxagliptin and Dapagliflozin. Qtern 5mg/10mg Tablet belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus adjunct to diet and exercise. Saxagliptin is a dipeptidyl peptidase-4 inhibitor that enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations. Dapagliflozin is a sodium-glucose cotransporter 2 inhibitor that removes excess sugar from the body via urine. Together, Qtern 5mg/10mg Tablet helps treat type-2 diabetes mellitus.

How Qtern 5mg/10mg Tablet Works

Qtern 5mg/10mg Tablet is a combination of two drugs: Saxagliptin (dipeptidyl peptidase-4 inhibitor) and Dapagliflozin (sodium-glucose cotransporter-2 inhibitors). Saxagliptin enhances glucose-mediated insulin secretion. Thus, it reduces fasting and post-prandial blood sugar concentrations. Dapagliflozin removes excess sugar from the body via urine. Together, Qtern 5mg/10mg Tablet helps treat type-2 diabetes mellitus.

Storage

Keep Qtern 5mg/10mg Tablet out of reach and sight of children.
Side effects of Qtern 5mg/10mg Tablet
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
  • Include lifestyle modification by normalising body weight and intake of a balanced diet.
  • Follow healthy patterns that are good for heart and reduce the fat level in your body.
  • Contact your doctor and follow the prescribed course for a speedy recovery.
  • Quit smoking and avoid intake of alcohol which can worsen the situation.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.

What if I have taken an overdose of Qtern 5mg/10mg Tablet

Take Qtern 5mg/10mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Overdose may cause life-threatening hypoglycaemia (low blood sugar). Its symptoms include extreme weakness, tremors, confusion, sweating, trouble speaking, fast heart rate, nausea, vomiting, rapid breathing, seizures, and fainting. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Qtern 5mg/10mg Tablet if you are allergic to any of its components. Inform your doctor if you have type-1 diabetes mellitus, pancreas disorder, AIDS, reduced kidney function, diabetic ketoacidosis, heart disease, liver problems, high/low blood pressure, infections, if you are older than 75years, if you are taking insulin, sulphonylurea or pioglitazone. Avoid taking Qtern 5mg/10mg Tablet if you are pregnant or breastfeeding. Qtern 5mg/10mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Avoid alcohol consumption while taking Qtern 5mg/10mg Tablet as it might cause unpleasant side-effects. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Qtern 5mg/10mg Tablet:
Co-administration of Qtern 5mg/10mg Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Gatifloxacin can be taken with Qtern 5mg/10mg Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Qtern 5mg/10mg Tablet:
Coadministration of Qtern 5mg/10mg Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Qtern 5mg/10mg Tablet can be taken with Gatifloxacin if prescribed by the doctor. Consult the doctor if you experience nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, urination, thirst, and hunger. Monitoring blood glucose levels is advised. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Qtern 5mg/10mg Tablet:
Co-administration of Qtern 5mg/10mg Tablet with Aliskiren may increase the risk of dehydration and low blood pressure.

How to manage the interaction:
If you are supposed to use Qtern 5mg/10mg Tablet and Aliskiren together, a doctor may adjust the dose and monitor you more frequently. However, if you experience dizziness, fainting, headache, lightheadedness, and/or changes in pulse or heart rate, contact a doctor. Do not discontinue the medication without consulting a doctor.
SaxagliptinBexarotene
Severe
How does the drug interact with Qtern 5mg/10mg Tablet:
Coadministration of Bexarotene and Qtern 5mg/10mg Tablet can increase the risk of developing pancreatitis (inflammation of the pancreas).

How to manage the interaction:
Co-administration of Bexarotene and Qtern 5mg/10mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like persistent nausea, vomiting, abdominal tenderness, and upper abdominal pain, especially that which is made worse after eating or radiates to the back, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SaxagliptinTirzepatide
Moderate
How does the drug interact with Qtern 5mg/10mg Tablet:
As tirzepatide and Qtern 5mg/10mg Tablet both work through similar pathways in the body, it is possible that using them together may result in an increase in side effects.

How to manage the interaction:
Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include foods rich in healthy carbohydrates and fibre, fruits, whole grains, and vegetables in your diet.

  • Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.

  • Follow a healthy diet and walk for at least 45 minutes to complement treatment with Qtern 5mg/10mg Tablet .

  • Maintain a healthy weight by exercising regularly.

  • Rest properly, avoid stress by doing meditation or yoga.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Qtern 5mg/10mg Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Qtern 5mg/10mg Tablet to prevent unpleasant side effects.

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Pregnancy

Unsafe

Qtern 5mg/10mg Tablet is not recommended for use during pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Unsafe

It is not known if Qtern 5mg/10mg Tablet passes into breast milk. Therefore, avoid taking Qtern 5mg/10mg Tablet if you are breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Caution

Generally, Qtern 5mg/10mg Tablet does not affect your ability to drive. However, in some cases, Qtern 5mg/10mg Tablet might cause dizziness or low blood sugar levels leading to sweating, shakiness, and changes in vision. Therefore, drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Qtern 5mg/10mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established.

Have a query?

FAQs

Qtern 5mg/10mg Tablet belongs to the anti-diabetic medicines used to treat type-2 diabetes mellitus adjunct to diet and exercise.

Qtern 5mg/10mg Tablet contains Saxagliptin and Dapagliflozin. Saxagliptin enhances glucose-mediated insulin secretion, thereby reduces fasting and post-prandial blood sugar concentrations. Dapagliflozin removes excess sugar from the body via urine. Together, Qtern 5mg/10mg Tablet helps treat type-2 diabetes mellitus.

Do not stop taking Qtern 5mg/10mg Tablet without consulting your doctor, as it may cause an increase in blood glucose levels. Continue taking Qtern 5mg/10mg Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Qtern 5mg/10mg Tablet .

Dehydration could be a side-effect of Qtern 5mg/10mg Tablet . Drink plenty of fluids if you experience any symptoms of dehydration such as dry mouth, feeling thirsty, tiredness, sleepiness, passing less urine, and fast heartbeat.

Qtern 5mg/10mg Tablet may sometimes lower the blood glucose levels more than normal, leading to hypoglycemia. Regularly monitor your blood sugar levels while taking Qtern 5mg/10mg Tablet . Hypoglycemia symptoms include headache, dizziness, drowsiness, shakiness, faintness, confusion, and visual disturbances.

Maintain a healthy diet by regular intake of carbohydrates. Eat your meals regularly, and do not exercise heavily for longer durations with an empty stomach.

Inform your doctor if you are allergic to Qtern 5mg/10mg Tablet , if you have type-1 diabetes mellitus, pancreas disorder, AIDS, reduced kidney function, diabetic ketoacidosis, heart disease, liver problems, high/low blood pressure, infections, if you are older than 75years, if you are taking insulin, sulphonylurea or pioglitazone. Also inform your doctor about all the other medicines you are taking and your health condition. If you are breastfeeding, pregnant or planning pregnancy, inform your doctor.

Qtern 5mg/10mg Tablet is not recommended in patients with history of a serious hypersensitivity reaction to Qtern 5mg/10mg Tablet , moderate to severe renal (kidney), impairment end-stage renal (kidney) disease (ESRD), or patients on dialysis. Qtern 5mg/10mg Tablet is not recommended to use for children below 18 years of age. Also inform your doctor if you are breastfeeding, pregnant or planning pregnancy before taking Qtern 5mg/10mg Tablet . However, consult your doctor if you have any concerns.

Qtern 5mg/10mg Tablet does not cause weight gain. In fact, it may lead to weight loss in some individuals. However, if you notice any changes in your body weight, maintain a healthy diet and do some physical activities.

Qtern 5mg/10mg Tablet is generally safe for people with normal kidney function. However, it should be used with caution in individuals with moderate to severe kidney impairment or those on dialysis. Dapagliflozin in Qtern 5mg/10mg Tablet works by helping the kidneys remove glucose from the bloodstream, which can be problematic for those with existing kidney issues. Therefore, it's important to inform your doctor if you have any history of kidney problems before starting Qtern 5mg/10mg Tablet .

Yes, it is important to manage your diet and exercise while taking Qtern 5mg/10mg Tablet . Managing blood sugar levels properly requires not only medication but also a good diet and regular exercise. Therefore, a well-balanced diet is part of a healthy lifestyle for people with type 2 diabetes.

If you accidentally take more than the prescribed dose of Qtern 5mg/10mg Tablet , it can lead to serious side effects, including life-threatening hypoglycaemia (low blood sugar). Symptoms of severe hypoglycaemia include, extreme weakness, tremors, confusion, sweating, trouble speaking, fast heart rate, nausea, vomiting, rapid breathing, seizures, and fainting. If you experience any these symptoms or suspect you have taken an overdose, please consult your doctor immediately.

Yes, Qtern 5mg/10mg Tablet can cause urinary tract infections (UTIs) as a common side effect. To prevent this, it's important to stay hydrated by drinking plenty of water to help flush out bacteria. Maintain good hygiene to reduce the risk of infection. Monitor signs of a urinary tract infection (UTI), such as pain or burning sensation during urination, frequent urination, or cloudy urine. If you experience any of these symptoms, please consult your doctor.

The duration for which you need to take Qtern 5mg/10mg Tablet depends on your individual health condition and how well you respond to the treatment. Typically, it is used as a long-term medication to help manage type 2 diabetes. Therefore, do not stop using Qtern 5mg/10mg Tablet without consulting your doctor and continue using Qtern 5mg/10mg Tablet as long as your has prescribed you.

If you miss a dose of Qtern 5mg/10mg Tablet , take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and take your regularly scheduled dose. Do not take double dose to make up for the missed one.

Qtern 5mg/10mg Tablet is generally considered as safe for long-term use only when prescribed by your doctor. However, it's important to have regular check-ups with your doctor to monitor your kidney function and overall health while taking Qtern 5mg/10mg Tablet .

The common side effects of Qtern 5mg/10mg Tablet are urinary tract infection, hypoglycaemia (low blood sugar), upper respiratory tract infection, and dyslipidaemia (high levels of lipids). Consult your doctor if any of these side effects persist or worsen.

Country of origin

Sweden

Manufacturer/Marketer address

Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Other Info - QTE0007

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