apollo
logo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
compositionComposition:RETEPLASE-18MG
prescription
Prescription Medicine
info
image icons
image icons
Best Price

₹36418 with coupons & bank offers*

View

RETELEX KIT INJECTION 2S is used in the treatment of ST-elevation myocardial infarction (STEMI) to lower the risk of heart failure and death. It contains Reteplase, which works by dissolving the blood clot that is blocking the heart's blood vessels. It may also treat a recent left bundle branch block (a delay/blockage of electrical impulses to the left side of the heart). Common side effects of RETELEX KIT INJECTION 2S are bleeding, bruising at the injection site, nausea or vomiting.

Read more
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
Get Extra 18% Off with Coupons
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

RETEPLASE-18MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About RETELEX KIT INJECTION 2S

RETELEX KIT INJECTION 2S is a tissue plasminogen activator indicated for the treatment of acute ST-elevation myocardial infarction (STEMI) to lower the risk of heart failure and death. STEMI is a very serious type of heart attack that occurs due to blockage of the heart’s major arteries.

RETELEX KIT INJECTION 2S contains Reteplase, which works by dissolving the blood clot that is blocking the heart blood vessel.

In some cases, RETELEX KIT INJECTION 2S may cause side effects such as bleeding, bruising at the injection site, nausea or vomiting. You are advised to talk to your doctor if any of the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. The efficacy and safety of RETELEX KIT INJECTION 2S in children have not been established. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of RETELEX KIT INJECTION 2S

RETELEX KIT INJECTION 2S is used in the treatment of ST-elevation myocardial infarction (STEMI). The detailed uses of RETELEX KIT INJECTION 2S are as follows:

  • Acute myocardial infarction (heart attack): RETELEX KIT INJECTION 2S helps dissolve blood clots in the coronary arteries, restoring blood flow to the heart muscle and reducing the risk of heart failure or death.
  • ST-elevation myocardial infarction (STEMI): RETELEX KIT INJECTION 2S is specifically indicated for this type of heart attack, where quick clot dissolution is critical.

Key Benefits

RETELEX KIT INJECTION 2S is a tissue plasminogen activator indicated for the treatment of acute ST-elevation myocardial infarction (STEMI) to reduce the risk of heart failure and death. RETELEX KIT INJECTION 2S contains Reteplase that works by dissolving the blood clot that is blocking the heart blood vessel. It may also be indicated in the treatment of a recent left bundle branch block (a delay/blockage of electrical impulses to the left side of the heart).

Side effects of Retelex Kit Injection 2s
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
  • Regularly exercise and have a balanced diet to maintain a healthy weight.
  • Eat fruits and vegetables to maintain a healthy weight.
  • Include vitamin K-rich foods in your diet for stable anticoagulation control.
  • Limit red and processed meats.
  • Avoid smoking and consumption of alcohol to improve your condition.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • RETELEX KIT INJECTION 2S will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How RETELEX KIT INJECTION 2S Works

RETELEX KIT INJECTION 2S contains Reteplase, which works by dissolving the blood clot that is blocking the heart blood vessel.
bannner image

Alcohol

Consult your doctor

Limited information is available. Please consult your doctor.

bannner image

Pregnancy

Caution

Please consult your doctor if you are pregnant. Your doctor will prescribe only if the potential benefits outweigh the potential risk to the foetus.

bannner image

Breast Feeding

Caution

Please consult your doctor if you are breastfeeding. Caution should be exercised whilst administering RETELEX KIT INJECTION 2S to a nursing mother.

bannner image

Driving

Consult your doctor

Limited information is available. Please consult your doctor.

bannner image

Liver

Caution

The potential risks with the therapy of RETELEX KIT INJECTION 2S may be increased in patients with severe liver dysfunction and should be weighed against the anticipated benefits. Please consult your doctor.

bannner image

Kidney

Caution

The potential risks of RETELEX KIT INJECTION 2S therapy may be increased in patients with severe renal dysfunction and should be weighed against the anticipated benefits. Please consult your doctor.

bannner image

Children

Caution

The efficacy and safety of RETELEX KIT INJECTION 2S in children have not been established.

bannner image

Heart

Safe if prescribed

RETELEX KIT INJECTION 2S is generally safe for heart patients if prescribed, but should be used under medical supervision.

bannner image

Geriatrics

Caution

RETELEX KIT INJECTION 2S should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of RETELEX KIT INJECTION 2S

Since RETELEX KIT INJECTION 2S is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Diet & Lifestyle Advise

  • Include vegetables, fruits and whole grains in your diet.
  • Stop smoking.
  • Be physically active every day.
  • Aim for a healthy weight.
  • Limit the consumption of alcohol.
  • Manage stress with meditation.
health query

Have a query?

How Soon It Starts Working

The time required for RETELEX KIT INJECTION 2S to start to work: RETELEX KIT INJECTION 2S ideally shows its action within 30 to 90 minutes after administration. The time for which the effects of RETELEX KIT INJECTION 2S last: The duration of action for RETELEX KIT INJECTION 2S is clinically unknown.

What if you forget to take RETELEX KIT INJECTION 2S

As this medication will be administered in a hospital by your healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight. • Keep RETELEX KIT INJECTION 2S out of sight and reach of children. • Cold chain - To be stored in cold places at 2ºC to 8ºC.
icon image

Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

RETELEX KIT INJECTION 2S should not be used if you are allergic to any of the components in RETELEX KIT INJECTION 2S, in patients with active internal bleeding, recent stroke, recent intracranial or intraspinal surgery or serious head trauma, intracranial neoplasm (brain tumour), arteriovenous malformation, or aneurysm (ballooning and weakened area in an artery), known bleeding diathesis (tendency to bleed or bruise easily), or severe uncontrolled hypertension. RETELEX KIT INJECTION 2S may cause bleeding, hypersensitivity reactions, or cholesterol embolism. Inform your doctor if you have/had recent major surgery, cerebrovascular disease, recent gastrointestinal/genitourinary bleeding, hypertension, subacute bacterial endocarditis, severe hepatic or renal disease, if you are over 75 years or if you are taking any oral anticoagulants. Consult your doctor if you are pregnant or breastfeeding. The safety and effectiveness of RETELEX KIT INJECTION 2S in children have not been established.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Inform your doctor if you are taking anti-coagulants (heparin, enoxaparin, warfarin, phenindione, aspirin, dipyridamole, ticlopidine, clopidogrel, vitamin K antagonists).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have/had cancer, stroke, high blood pressure, active ulcer in the stomach or intestine, portal hypertension, inflammation of the pancreas, bleeding behind or in the eye, or severe liver or kidney problems.

ReteplaseEnoxaparin
Severe
ReteplaseIbrutinib
Severe

Drug-Drug Interactions

Login/Sign Up

ReteplaseEnoxaparin
Severe
How does the drug interact with Retelex Kit Injection 2s:
Combining Retelex Kit Injection 2s with Enoxaparin can increase the risk or severity of bleeding.

How to manage the interaction:
Although there is a possible interaction between Enoxaparin and Retelex Kit Injection 2s, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like bleeding, bruising, dizziness, or severe headache, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
ReteplaseIbrutinib
Severe
How does the drug interact with Retelex Kit Injection 2s:
Co-administration of Ibrutinib with Retelex Kit Injection 2s can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Ibrutinib with Retelex Kit Injection 2s together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
ReteplaseFondaparinux
Severe
How does the drug interact with Retelex Kit Injection 2s:
Taking Retelex Kit Injection 2s with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between fondaparinux and Retelex Kit Injection 2s, you can take these medicines together if prescribed by your doctor. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
ReteplaseCangrelor
Severe
How does the drug interact with Retelex Kit Injection 2s:
Co-administration of Cangrelor with Retelex Kit Injection 2s can increase the risk of bleeding.

How to manage the interaction:
Although taking Cangrelor and Retelex Kit Injection 2s together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs, it's important to contact a doctor right away: difficulty with bleeding, complications, bruising, feeling dizzy or lightheaded, dark or sticky stools, intense headache, weakness, or bleeding or vomiting. Do not stop using any medications without talking to a doctor.
ReteplaseApixaban
Severe
How does the drug interact with Retelex Kit Injection 2s:
Coadministration of Retelex Kit Injection 2s and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Retelex Kit Injection 2s and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
ReteplaseDabigatran etexilate
Severe
How does the drug interact with Retelex Kit Injection 2s:
Taking Dabigatran etexilate with Retelex Kit Injection 2s can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Retelex Kit Injection 2s together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
ReteplasePrasugrel
Severe
How does the drug interact with Retelex Kit Injection 2s:
Taking Prasugrel with Retelex Kit Injection 2s can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Prasugrel with Retelex Kit Injection 2s can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

RETELEX KIT INJECTION 2S is used to treat ST-elevation myocardial infarction (STEMI).
RETELEX KIT INJECTION 2S works by dissolving the blood clot that is blocking the heart's blood vessels.
RETELEX KIT INJECTION 2S may increase the risk of bleeding. The sites of bleeding could be internal or external. Talk to your doctor if you have any concerns.
Heparin and RETELEX KIT INJECTION 2S are incompatible. RETELEX KIT INJECTION 2S should not be administered through an intravenous line containing heparin. Please consult your doctor if you have any concerns.
RETELEX KIT INJECTION 2S will be administered by a healthcare professional in a clinical setting. Do not attempt to administer it yourself. A trained healthcare professional will ensure safe and proper administration.
Yes, RETELEX KIT INJECTION 2S is safe when used under the doctor’s supervision. It is used in the treatment of ST-elevation myocardial infarction (STEMI). However, it may cause some side effects like bleeding, bruising at the injection site, nausea, or vomiting in some cases. You are advised to talk to your doctor if any of the side effects persist or worsen.
RETELEX KIT INJECTION 2S may interact with anti-coagulants like heparin, enoxaparin, warfarin, phenindione, aspirin, dipyridamole, ticlopidine, clopidogrel, and vitamin K antagonists. So, it’s best to consult your doctor before taking anti-coagulants or any other medications along with RETELEX KIT INJECTION 2S.
RETELEX KIT INJECTION 2S helps prevent blood clots from forming in your legs, lungs, heart, and brain. You may not feel any immediate effects after taking the medicine, but that doesn't mean it's not working. Continue taking the medicine exactly as prescribed by your doctor, even if you don't notice any difference.
The common side effects of RETELEX KIT INJECTION 2S may include bleeding, bruising at the injection site, nausea, or vomiting. You are advised to talk to your doctor if any of the side effects persist or worsen.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. DailyMed Database. Druginfo.Cfm Clinical Monograph. Bethesda, MD: National Library of Medicine; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Retavase Pi. [Accessed on 02 Jun. 2026]Check here
  3. Retefast Intravenous Bolus Injection. [Accessed on 02 Jun. 2026]Check here
  4. Ministry of Health and Family Welfare. National Formulary of India (NFI) 2021. 6th ed. New Delhi, India: IPC; 2021. Clinical Drug Monographs: Retefuse 18Mg Injection

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - RET0064
whatsapp Floating Button
Buy Now
Add to Cart