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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Septran 100 mg Tablet is used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). It contains Trimethoprim and Sulfamethoxazole, which stop the growth of bacteria and kill them. Therefore, it helps treat bacterial infections. In some cases, you may experience specific common side effects, such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Koye Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Septran 100 mg Tablet

Septran 100 mg Tablet is used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. Septran 100 mg Tablet does not work against infections caused by the virus, including cold and flu. 

Septran 100 mg Tablet combines two antibiotics: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for forming proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Septran 100 mg Tablet stops the growth of bacteria and kills them. Therefore, it helps treat bacterial infections.

Your doctor will decide the dose and duration of Septran 100 mg Tablet based on your condition and the severity of the infection. In some cases, you may experience specific common side effects, such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Septran 100 mg Tablet , please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take Septran 100 mg Tablet on your own as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking Septran 100 mg Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption to prevent unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. Septran 100 mg Tablet is not recommended for children below 12 years.

Uses of Septran 100 mg Tablet

Septran 100 mg Tablet is used to treat bacterial infections. The detailed uses of Septran 100 mg Tablet are as follows:
•Urinary Tract Infections (UTIs): Septran 100 mg Tablet is often utilized to treat urinary tract infections caused by susceptible bacteria. It prevents bacterial growth and allows the immune system to eliminate the disease.
•Respiratory Tract Infection: Septran 100 mg Tablet can be used to treat specific respiratory infections, including bronchitis and pneumonia, and prevent breathing difficulties caused by bacterial infection.
•Gastrointestinal infections: Septran 100 mg Tablet is often helpful against gastrointestinal infections, especially those caused by Shigella or Salmonella strains. It reduces symptoms like diarrhea and abdominal pain.
•Skin and Soft Tissue Infections: Septran 100 mg Tablet effectively treats bacterial skin infections such as infected cuts, burns, or surgical wounds.
•Pneumocystis Pneumonia (PCP): Septran 100 mg Tablet prevents a potentially life-threatening condition in those with weakened immune systems.

Directions for Use

Swallow Septran 100 mg Tablet as a whole with water; do not crush or chew it.

Medicinal Benefits

Septran 100 mg Tablet belongs to the group of medicines called ‘antibiotics’ used to treat various bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Septran 100 mg Tablet is a combination of two antibiotics: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Septran 100 mg Tablet kills the bacteria and stops their growth. Therefore, it helps treat bacterial infections. Septran 100 mg Tablet is a broad-spectrum antibiotic which is active against a wide range of gram-positive and gram-negative bacteria such as Streptococcus pneumonia, Escherichia coli, Klebsiella species, Enterobacter species, Haemophilus influenzae, etc.

How Septran 100 mg Tablet Works

Septran 100 mg Tablet is a combination of two antibiotics: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Septran 100 mg Tablet stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Septran 100 mg Tablet

Do not take more than the prescribed dose of Septran 100 mg Tablet as it may cause overdose. The symptoms of overdose include headache, dizziness, nausea, vomiting, confusion, loss of appetite, drowsiness, or mental depression. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Septran 100 mg Tablet if you are allergic to any of its contents; if you have severe liver or kidney problems, thrombocytopenia (low levels of platelets in the blood), or porphyria (rare blood problem). Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pain. Talk to your doctor before taking Septran 100 mg Tablet if you have severe allergies, asthma, ulcers, blood disorders, thyroid dysfunction, diabetes, are elderly, underweight or malnourished; if you have a folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency, or high levels of potassium in the blood. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Septran 100 mg Tablet to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Septran 100 mg Tablet:
Taking Tranylcypromine with Septran 100 mg Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Septran 100 mg Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Septran 100 mg Tablet:
Taking Safinamide with Septran 100 mg Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Septran 100 mg Tablet is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Septran 100 mg Tablet:
Co-administration of Septran 100 mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Septran 100 mg Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Septran 100 mg Tablet:
Co-administration of Clonidine and Septran 100 mg Tablet may increase the risk and severity of high blood pressure.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Septran 100 mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache or heart palpitations, contact your doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Septran 100 mg Tablet:
Taking Paroxetine with Septran 100 mg Tablet can cause sedation, dry mouth, blurred vision, constipation.

How to manage the interaction:
Although there is a possible interaction between Paroxetine and Septran 100 mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience dry mouth, blurred vision, constipation contact your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Septran 100 mg Tablet:
Using Septran 100 mg Tablet together with Sumatriptan might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although there is a possible interaction between Sumatriptan and Septran 100 mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea call a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Septran 100 mg Tablet:
Combining flumazenil together with Septran 100 mg Tablet can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Although taking Flumazenil and Septran 100 mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience irregular heartbeat, chest tightness, blurred vision, nausea and seizures contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
TrimipramineEphedrine
Severe
How does the drug interact with Septran 100 mg Tablet:
Co-administration of Ephedrine and Septran 100 mg Tablet together may increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Ephedrine and Septran 100 mg Tablet, but it can be taken if prescribed by a doctor. It's important to maintain your blood pressure. Do not stop using any medications without talking to a doctor.
How does the drug interact with Septran 100 mg Tablet:
When Vilazodone is taken with Septran 100 mg Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Septran 100 mg Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Septran 100 mg Tablet:
Using Granisetron together with Septran 100 mg Tablet can increase the risk of a serious condition called serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a mood stabilizer).

How to manage the interaction:
Co-administration of Granisetron with Septran 100 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of the following symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, blurred vision, muscle spasm, stomach cramp, nausea, vomiting, diarrhea, dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations it is recommended to contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTIC COMBINATION
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Alcohol

Unsafe

Avoid alcohol consumption while taking Septran 100 mg Tablet to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

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Pregnancy

Caution

Please consult your doctor before taking Septran 100 mg Tablet if you are pregnant. Your doctor will prescribe Septran 100 mg Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding, your doctor will prescribe Septran 100 mg Tablet only if the benefits outweigh the risks.

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Driving

Caution

It is unknown whether Septran 100 mg Tablet affects your ability to drive and operating machinery. Drive only if you are physically stable and mentally focussed.

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Liver

Caution

Please consult your doctor before taking Septran 100 mg Tablet if you have liver impairment/liver disease. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Kidney

Caution

Septran 100 mg Tablet to be taken with caution, especially if you have a history of kidney impairment/kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Septran 100 mg Tablet is not recommended for children below 12 years.

Have a query?

FAQs

Septran 100 mg Tablet is used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma).

Septran 100 mg Tablet is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. By inhibiting these, Septran 100 mg Tablet kills the bacteria and stops their growth. Thereby, helps to treat bacterial infections.

Septran 100 mg Tablet causes thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

Diarrhoea might be a side-effect of Septran 100 mg Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Septran 100 mg Tablet and consult your doctor. Do not take anti-diarrheal medicine on your own.

It is recommended to complete the course of Septran 100 mg Tablet even if you feel better as it is an antibiotic, and leaving it in between may lead to recurring infections. Continue taking Septran 100 mg Tablet for as long as your doctor has prescribed to treat your condition effectually.

Do not take Septran 100 mg Tablet on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.

Septran 100 mg Tablet may affect certain laboratory test results. Inform the person doing the tests that you are taking Septran 100 mg Tablet .

Septran 100 mg Tablet may cause high levels of potassium in the blood, which could lead to abnormal heartbeats (palpitations). Regular monitoring of potassium levels and heart rate is advised while taking Septran 100 mg Tablet .

You can take Septran 100 mg Tablet with or without as advised by your doctor. Take Septran 100 mg Tablet preferably with food to avoid nausea or diarrhoea.

No, Septran 100 mg Tablet is not an addiction causing medicine. But the dose and duration should be followed as prescribed by your doctor.

Yes, Septran 100 mg Tablet can be used for urinary tract infection as Septran 100 mg Tablet is used to prevent infections caused by bacteria.

Pimples are caused due to various reasons. Therefore, please consult your doctor before taking Septran 100 mg Tablet . If you have any concerns regarding acne, discuss with your doctor.

Yes, Septran 100 mg Tablet is a stronger antibiotic. It contains two antibiotics namely, Sulfamethoxazole and Trimethoprim.

Septran 100 mg Tablet can cause side effects such as high levels of potassium in your blood, which can cause abnormal heart beats. Also, it may cause fungal infections like thrush or candidiasis which can affect mouth or vagina and other common side effects like headache, nausea, diarrhoea and skin rashes. If these effects worsen or persist, consult your doctor.

Yes, Septran 100 mg Tablet is safe to use in most patients. However consult your doctor if you experience any side effects like nausea, vomiting, skin rash, allergic reaction.

Yes, Septran 100 mg Tablet can cause nausea and vomiting. If these persist or worsen, consult your doctor.

Septran 100 mg Tablet is contraindicated in patients who have a history of drug-induced immune thrombocytopenia from using trimethoprim and/or sulfonamides, who have a known hypersensitivity to these medications, or who have megaloblastic anemia from a folate deficiencies and in patients with severe renal insufficiency or obvious liver impairment.

Avoid spicy, acidic, and greasy foods while taking Septran 100 mg Tablet as they may increase your risk of side effects such upset stomach and diarrhoea. Also, Septran 100 mg Tablet can interact with alcohol. It's best to avoid drinking alcohol while taking Septran 100 mg Tablet .

Yes, Septran 100 mg Tablet expires. The expiry date can be found on the packaging.

No, do not stop taking Septran 100 mg Tablet without first consulting your doctor. Complete the full course of treatment even if you feel better as you may notice an improvement in your symptoms before the infection is cured completely.

If you miss a dose of Septran 100 mg Tablet , do not worry. Take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for the missed dose.

If you don't feel better after completing the full course of treatment with Septran 100 mg Tablet , inform your doctor. Also, let your doctor know if your symptoms are worsening while taking Septran 100 mg Tablet .

Septran 100 mg Tablet should be used in children above 12 years of age if advised by a doctor.

Avoid taking Septran 100 mg Tablet if you are allergic to Sulfamethoxazole, Trimethoprim or any other ingredients of Septran 100 mg Tablet . If you have severe liver or kidney problems, or have ever had thrombocytopenia (blood problem causing bleeding or bruises) or have porphyria (a rare blood problem), inform your doctor before taking Septran 100 mg Tablet .

Take Septran 100 mg Tablet as advised by your doctor. It should be taken with food and it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose. Swallow it as whole with a glass of water. Do not crush or chew it.

Store the Septran 100 mg Tablet in the original package at room temperature. Keep it out of the reach and sight of children.

Country of origin

India

Manufacturer/Marketer address

A-10, 3rd Floor, Art Guild House, Phoenix Market City Annexe, LBS Marg, Kurla (West), Mumbai - 400070
Other Info - SEP0009

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