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Sigmaderm N Cream is used to treat various fungal and bacterial skin infections. It treats skin inflammation due to allergies or irritants, eczema (inflamed, itchy, cracked and rough skin patches), psoriasis (skin cells multiply rapidly to form bumpy red patches covered with white scales), ringworm, athlete's foot (fungal infection between the toes), jock itch (fungal infection in the skin of the genitals, inner thighs and buttocks), insect bites, and stings. It stops the growth of fungi and bacteria. Also, it blocks the production of prostaglandins (chemical messengers) that make the affected area red, swollen and itchy. It may cause common side effects such as burning, irritation, itching and redness at the application site.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Maneesh Pharmaceuticals Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Sigmaderm N Cream

Sigmaderm N Cream is a topical combination cream prescribed to treat various skin infections that are accompanied by redness, swelling, and itching. It is specifically used when a skin condition is complicated by both fungal and bacterial infections. This cream helps clear up the underlying microbial causes while rapidly relieving uncomfortable skin symptoms. Skin infections can be uncomfortable, frustrating, and sometimes embarrassing, and they may affect your confidence or daily comfort. The good news is that, with proper diagnosis and treatment, most skin infections improve well and symptoms can be effectively controlled.  

To get the best results, you must apply Sigmaderm N Cream consistently at the same times every day as directed by your doctor. It is designed for external use on the skin only, and you do not need to alter your meals as food does not affect how this topical cream works. Keeping the affected skin clean, dry, and exposed to fresh air as much as possible will also help speed up your recovery.

While using Sigmaderm N Cream, you may experience mild, temporary skin reactions at the application site, such as slight burning, irritation, or dryness. These symptoms usually go away on their own as your skin adjusts to the medication. However, you should contact your doctor immediately if you develop severe skin peeling, blistering, or signs of an allergic reaction.

Talk to your doctor before using Sigmaderm N Cream if you have a history of skin thinning, poor blood circulation, or immune system issues. You should not use this medicine if you have viral skin infections like chickenpox or herpes, or if you are allergic to any of its components.

Although this cream is applied to the skin, it is important to tell your doctor about all other medications you are using, as some topical products can interact and increase the risk of skin irritation. If you are pregnant, planning to become pregnant, breastfeeding, or caring for an elderly patient, consult your doctor before using this medicine. Do not self-medicate during pregnancy, and only use this medicine under medical supervision. 

Uses of Sigmaderm N Cream

The following are some of the common conditions for which this combination medicine may be prescribed:

  • Inflamed bacterial skin infections: Sigmaderm N Cream helps clear up bacterial skin issues while reducing the painful swelling and redness that come with them.
  • Fungal skin infections with inflammation: It effectively treats conditions like ringworm or athlete's foot when they are accompanied by severe itching, scaling, and irritation.
  • Infected eczema or dermatitis: It provides relief for stubborn, swollen skin patches that have become infected due to scratching or cracked skin.
     

Key Benefits

Sigmaderm N Cream offers targeted relief by addressing multiple symptoms of skin discomfort at the same time:

  • Rapid relief from itching and redness: The soothing anti-inflammatory action quickly calms irritated skin, helping you resist the urge to scratch and prevent further damage.
  • Combats multiple types of germs: By targeting both bacteria and fungi, it stops complex, mixed infections from spreading to other parts of your body.
  • Promotes faster skin healing: By clearing away harmful microbes and reducing swelling, it allows your skin's natural barrier to repair itself more quickly.
     
Side effects of Sigmaderm N Cream 10 gm
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce irritation.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin soothing.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Burning sensation is an abnormal side effect that needs medical attention. To relieve the burning feeling, your doctor may prescribe painkillers or antidepressants.
  • Focused exercises can improve strength and reduce burning by soothing muscles.
  • Change in lifestyle and improving nutrition can reduce the causes of burning sensation and provide relief.
  • Your doctor may suggest nerve block injections as it is related to sensation in the skin.
  • Burning feeling in a specific area would need mild electrical currents to reduce pain that targets the nerve affected. This practice must be done only if your doctor mentions it.

Directions for Use

  • Sigmaderm N Cream is for external use only.
  • Follow your doctor's guidance regarding the dosage and timing of this medication for optimal effectiveness.
  • Apply a thin layer of Sigmaderm N Cream to the affected areas of your skin with clean and dry hands. You can also apply it with a piece of clean cotton wool or gauze swab. Gently rub the medicine into the skin until it has disappeared.
  • Wash your hands before and after applying it unless the treatment is for your hands.
  • If Sigmaderm N Cream accidentally comes in contact with your eyes, nose, or mouth, rinse immediately with cold water.

How Sigmaderm N Cream Works

Sigmaderm N Cream contains three active medicines that work together to treat skin infections associated with inflammation, fungal growth, and bacterial infection. Betamethasone is a corticosteroid that works mainly at the site where it is applied by reducing the production of inflammatory chemical messengers that cause redness, swelling, itching, and irritation. This helps provide rapid relief from inflammation and discomfort. Clotrimazole is an antifungal medicine that works by inhibiting the production of ergosterol, an essential component of the fungal cell membrane. Without enough ergosterol, the fungal cell membrane becomes damaged and unable to function properly, helping eliminate the fungal infection. Neomycin is an antibiotic that works by stopping bacteria from producing the proteins they need to grow and multiply. This helps control and eliminate bacterial infections affecting the skin. Together, these medicines help clear fungal and bacterial infections, reduce inflammation, relieve itching and irritation, and promote healing of the affected skin.
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Alcohol

Safe if prescribed

No interactions were found/ established. Please consult your doctor before using Sigmaderm N Cream.

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Pregnancy

Caution

There is limited data on how the Sigmaderm N Cream affects pregnancy. Please consult your doctor if you are planning to become pregnant or are already pregnant before starting Sigmaderm N Cream.

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Breast Feeding

Caution

Please consult your doctor before using Sigmaderm N Cream if you are breastfeeding. If you need to apply the cream or ointment on your breasts, don't do this shortly before giving a feed.

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Driving

Safe if prescribed

Sigmaderm N Cream has no or negligible influence on the ability to drive or use machines.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment before starting Sigmaderm N Cream.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before starting Sigmaderm N Cream.

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Children

Caution

Sigmaderm N Cream is recommended for children only with a doctor's advice.

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Heart

Safe if prescribed

Sigmaderm N Cream is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Although Sigmaderm N Cream is for topical use, caution should be exercised when used in elderly patients.

What if I have taken an overdose of Sigmaderm N Cream

Using too much of this cream or applying it over very large areas of skin for a long time can lead to increased absorption into the body, which may cause unwanted side effects. If you have applied substantially more cream than prescribed or used it over large areas of skin for a prolonged period, wash off any excess medication and contact your doctor or pharmacist for advice. If someone accidentally swallows the cream, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Keep the Area Clean and Dry: Keep the infected skin area clean and completely dry, as moisture encourages the growth of fungi and bacteria.
  • Wear Breathable Clothing: Wear loose-fitting, breathable cotton clothing to prevent sweat accumulation and friction against the infected skin.
  • Avoid Scratching the Skin: Avoid scratching or picking at the infected area, as this can spread the infection to other parts of your body or introduce new bacteria.
  • Prevent the Spread of Infection: Use separate towels, clothing, and bedsheets from others to prevent spreading the infection, and wash these items in hot water regularly.
  • Avoid Skin Irritants: Avoid using harsh soaps, perfumed cosmetics, or abrasive scrubs on the treated skin area, as they can cause further irritation.

 

health query

Have a query?

How Soon It Starts Working

The time required for Sigmaderm N Cream to start to work: The time required for Sigmaderm N Cream to show its action is unknown. The time for which the effects of Sigmaderm N Cream last: The duration of action for Sigmaderm N Cream is not clinically established.

What if you forget to take Sigmaderm N Cream

If you forget to apply Sigmaderm N Cream, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and continue with your regular routine. Do not apply extra cream to make up for a missed dose.

Storage

•Store the medicine according to the temperature stated on the product packaging. Most formulations should be stored at room temperature below the manufacturer-recommended limit. •Keep the tube tightly closed when not in use to help prevent contaminat

Drug Warnings

  • For External Use Only: Only apply this medication to your skin; keep it far away from your eyes, nose, mouth, and inside your ears.
  • Use on Sensitive Areas Only if Directed: Do not use this cream on your face, underarms, or groin area unless your doctor has specifically instructed you to do so.
  • Avoid Prolonged Use: Avoid using Sigmaderm N Cream for longer than the prescribed period, as prolonged use can cause your skin to become thin, weak, or easily bruised.
  • Inspect Before Use: Check the tube before use to ensure the seal is intact and the cream does not look discoloured or separated.
  • Do Not Share Medication: Do not share this medication with anyone else, even if they have skin symptoms that look similar to yours.
  • Complete the Full Treatment Course: Continue using the medicine for the full duration prescribed by your doctor, even if your symptoms improve earlier, to help ensure the infection is completely treated.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Before using Sigmaderm N Cream, inform your doctor about any other medicines you are using on your skin. Certain topical treatments may increase the risk of side effects when used together.

  • Other Topical Corticosteroids: Using other topical corticosteroid creams or ointments at the same time may increase the risk of skin thinning and other steroid-related side effects.
  • Other Topical Medicines: Applying multiple medicated creams, ointments, or lotions to the same area may increase skin irritation or affect how the treatments work.
  • Immunosuppressive Medicines: Medicines that weaken the immune system may increase susceptibility to infections and should be discussed with your doctor before use.

Drug-Disease Interactions

Some medical conditions can affect whether this medicine is suitable for you. Make sure your doctor is aware of any current or previous skin conditions before starting treatment.

  • Viral skin infections: Do not use this medication if you have chickenpox, shingles, herpes, or other viral skin conditions, as it can worsen these infections.
  • Tuberculosis of the skin: This medicine should not be applied to areas affected by skin tuberculosis, as it may interfere with your body's response to the condition.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS AND CORTICOSTEROIDS]

FAQs

Sigmaderm N Cream is used to treat certain fungal and bacterial skin infections associated with inflammation. It helps relieve symptoms such as redness, swelling, itching, and irritation. It may be prescribed for conditions such as infected eczema, ringworm, athlete’s foot, jock itch, insect bites and stings, and other inflammatory skin conditions caused or complicated by susceptible fungal or bacterial infections. Use Sigmaderm N Cream only as directed by your doctor.
Sigmaderm N Cream is for external use only. Avoid contact with eyes. If Sigmaderm N Cream gets into your eyes, nose, mouth or vagina, rinse with water. Do not put a bandage or a dressing on the affected area while using Sigmaderm N Cream unless advised by the doctor. Do not apply Sigmaderm N Cream on sunburns, open wounds, lesions and blisters.
Sigmaderm N Cream should be used with caution and under doctor's supervision if you have pituitary gland diseases, cataract or glaucoma, diabetes, liver and kidney diseases. Using corticosteroids (Betamethasone) on the skin may sometimes cause systemic immunosuppression while treating infections. This condition may worsen the infections, hence Sigmaderm N Cream should be carefully used with patients with active infections.
No, Sigmaderm N Cream is not recommended for treating diaper rash unless specifically prescribed by a doctor. The medicine contains betamethasone, a potent corticosteroid that may be excessively absorbed through an infant's skin, especially under diapers. This can increase the risk of serious side effects such as adrenal suppression, Cushing's syndrome, and increased pressure in the brain.
Sigmaderm N Cream may not work for skin infections like viral skin infections, such as chickenpox, shingles, cold sores or herpes simplex, bacterial infections like impetigo, lesions caused by tuberculosis or syphilis, acne vulgaris (spots), rosacea, perioral dermatitis (red spotty rash around the mouth) and widespread plaque psoriasis. Please reach out to a doctor for more information.
You are required to maintain at least a three-hour gap after application of Sigmaderm N Cream if you are using more than one topical medicine.
Sigmaderm N Cream may start relieving itching, redness, and inflammation within a few days of treatment. However, complete improvement may take several weeks depending on the condition being treated. Continue using the medicine for the full duration prescribed by your doctor, even if symptoms improve earlier. Consult your doctor if symptoms do not improve within 1–2 weeks or if they worsen.
Yes, it is safe to use Sigmaderm N Cream if prescribed by the doctor.
Do not stop using Sigmaderm N Cream without consulting your doctor, even if your symptoms improve. Stopping treatment too early may allow the infection or inflammation to return and may reduce the effectiveness of treatment. Continue using the medicine for the full duration prescribed by your doctor.
Apply a thin layer of Sigmaderm N Cream with clean and dry hands on the skin's affected areas. You can also apply it with a piece of clean cotton wool or gauze swab on the skin. Gently rub the medicine into the skin until it has disappeared.
No, do not overuse Sigmaderm N Cream or apply it in large amounts as it does not give quick or better results but increases the risk of side effects.
In some cases, Sigmaderm N Cream may cause side effects like burning, irritation, itching and redness at the application site. These side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, please consult your doctor.
Sigmaderm N Cream should not be applied by people who are allergic to any of its components. Do not use it on sunburns, lesions, blisters and open wounds.
Sigmaderm N Cream should be used during pregnancy or breastfeeding only if advised by your doctor. Although the medicine is applied to the skin, some of its components may be absorbed into the bloodstream. Your doctor will assess whether the benefits outweigh any potential risks before recommending its use.
Store Sigmaderm N Cream at room temperature, protected from light and moisture. Do not freeze. Keep it out of sight and reach of children.
No, you should not use Sigmaderm N Cream on your face or to treat acne. Using this strong topical medication on your face can cause skin thinning, redness, and other unwanted side effects.
Skin thinning is a serious side effect that can occur if this cream is used for too long or on delicate areas. If you notice your skin becoming thin, fragile, or bruising easily, contact your doctor immediately to discuss adjusting or stopping your treatment.
No. This medicine is intended for specific inflammatory skin conditions associated with fungal and/or bacterial infection. Using it on the wrong type of rash may worsen the condition or delay proper treatment.

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Country of origin

INDIA

Manufacturer/Marketer address

Plot No. 29-33, Ancillary Industrial Plots, Govandi, Mumbai - 400 043.
Other Info - SIG0011
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