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Tofaciz 5 mg Tablet 60's

Manufacturer/Marketer

Assentus Biogenics Pvt Ltd

Composition

TOFACITINIB-5MG

Consume Type

ORAL

In Stock

Prescription Required
Product Details

About Tofaciz 5 mg Tablet 60's

Tofaciz 5 mg Tablet 60's belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is an inflammatory condition of the joints, often associated with psoriasis. Ulcerative colitis is an inflammatory disease of the large intestine.
 
Tofaciz 5 mg Tablet 60's contains 'Tofacitinib' which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis. 
 
In some cases, you may experience common side-effects such as diarrhoea, headache, upper respiratory tract infection, cold, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Inform your doctor if you have an active infection, if you have a condition that increases the chance of having infections, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids. Avoid taking Tofaciz 5 mg Tablet 60's if you are pregnant or breastfeeding. Tofaciz 5 mg Tablet 60's is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Tofaciz 5 mg Tablet 60's

Rheumatoid arthritis, Psoriatic arthritis, Ulcerative colitis.

Medicinal Benefits

Tofaciz 5 mg Tablet 60's belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Tofaciz 5 mg Tablet 60's works by blocking Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis. Tofaciz 5 mg Tablet 60's is indicated for patients with moderate to severe rheumatic arthritis, and psoriatic arthritis who have had intolerance or inadequate response to methotrexate or DMARDs (Disease-Modifying Anti-Rheumatic Drugs).

Directions for Use

Swallow Tofaciz 5 mg Tablet 60's as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tofaciz 5 mg Tablet 60's

  • Headache
  • Diarrhoea
  • Vomiting
  • Nausea
  • Upper respiratory tract infection
  • Cold
  • High blood pressure

In-Depth Precautions and Warning

Drug Warnings

Do not take Tofaciz 5 mg Tablet 60's if you are allergic to any of its components; if you have a severe infection, bloodstream infection, active tuberculosis, or if you have severe liver problems such as cirrhosis. Avoid taking Tofaciz 5 mg Tablet 60's if you are pregnant or breastfeeding. Inform your doctor if you have an infection, symptoms of infection, a condition that increases chances of infection, are taking any medicines that affect the immune system; have or had a history of tuberculosis, or were in close contact with someone who has/had tuberculosis; chronic lung disease, liver problems, hepatitis B/C, cancer, are at a high risk of developing skin cancer, inflammation/ulcers of the large intestine, kidney problems, planning to get vaccinated, heart problems, high cholesterol, high blood pressure, heart attack, diabetes, or blood clotting problems. If your white blood cell count or red blood cell count is low, avoid taking Tofaciz 5 mg Tablet 60's. Tofaciz 5 mg Tablet 60's is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug Interactions

Drug-Drug Interactions: Tofaciz 5 mg Tablet 60's may interact with antibiotic (rifampicin), anti-fungal (fluconazole, ketoconazole), immunosuppressant (azathioprine, mercaptopurine, cyclosporine, tacrolimus), corticosteroids (prednisone).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have infections, bloodstream infection, severe liver problems, tuberculosis, blood clot problems, diabetes, high cholesterol, intestinal perforation, or gastrointestinal obstruction.

Drug-Drug Interactions Checker List:

  • RIFAMPICIN
  • FLUCONAZOLE
  • KETOCONAZOLE
  • AZATHIOPRINE
  • MERCAPTOPURINE
  • CYCLOSPORINE
  • TACROLIMUS
  • PREDNISONE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      It is not known if alcohol interacts with Tofaciz 5 mg Tablet 60's, so please consult a doctor.

    • Safety Warning

      Pregnancy

      unsafe

      Tofaciz 5 mg Tablet 60's must not be taken during pregnancy. If you are a woman of child-bearing potential, use effective contraception during the treatment with Tofaciz 5 mg Tablet 60's and for 4 weeks after discontinuation.

    • Safety Warning

      Breast Feeding

      unsafe

      Avoid breastfeeding while taking Tofaciz 5 mg Tablet 60's. Please consult a doctor if you have any concerns.

    • Safety Warning

      Driving

      safe if prescribed

      Tofaciz 5 mg Tablet 60's generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Tofaciz 5 mg Tablet 60's is not recommended for patients with severe liver problems.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      unsafe

      Tofaciz 5 mg Tablet 60's is not recommended for children below 18 years as safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
    • Performing yoga may also help in improving joint flexibility and pain management.
    • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
    • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
    • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
    • Acupuncture, massage and physical therapy may also be helpful.
    • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
    • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
    • Avoid smoking and alcohol consumption.

    Special Advise

    • Your doctor may advise you to get a blood test done before starting treatment with Tofaciz 5 mg Tablet 60's, after 4-8weeks of treatment and then every three months to determine your blood cell count.
    • Your doctor might advise regular tests to determine blood cholesterol levels and liver functioning.
    • Inform your doctor if you notice painful blisters on the skin or if you experience breathing difficulties.
    • If you are a woman of child-bearing potential, use effective contraception during the treatment with Tofaciz 5 mg Tablet 60's and for 4 weeks after discontinuation.

    Other Information (TOF0056)

    This item is Not Returnable.

    Expires on or after - Mar-23

    Patients Concern

    Disease/Condition Glossary

    Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

    Psoriatic arthritis: It is a type of inflammatory arthritis which occurs in patients with psoriasis. It could also occur in patients without psoriasis, particularly in those who have relatives with psoriasis. It affects large joints in the lower extremities, distal joints of toes and fingers, back and pelvis. Symptoms include inflammation of joints, difficulty moving, swelling, patches of red, scaly skin and pain.

    Ulcerative colitis: It is a type of chronic inflammatory bowel disease that causes inflammation of the lining of the large intestine (colon) and produces ulcers on the lining of the colon, which may cause bleeding and discharge of pus and mucus. The common symptoms include bloody stools, stomach pain, rectal pain, diarrhoea, fever, and weight loss. Additionally, it may cause other problems such as joint pain or swelling, mouth sores, skin problems, decreased appetite or nausea. 

    FAQs

    Tofaciz 5 mg Tablet 60's works by blocking Janus kinase enzyme, thereby lowers inflammation and symptoms associated with rheumatoid and psoriatic arthritis.

    Hypertension/high blood pressure could be a side-effect of Tofaciz 5 mg Tablet 60's. Consult your doctor before taking Tofaciz 5 mg Tablet 60's if you have high blood pressure or if you are taking anti-hypertensive medicines.

    Diarrhoea might be a side-effect of Tofaciz 5 mg Tablet 60's. Eat non-spicy meals and drink plenty of fluids to prevent dehydration if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

    Tofaciz 5 mg Tablet 60's might impair fertility in females of reproductive potential. It is not known if the effect is reversible. Therefore, talk to a doctor before starting Tofaciz 5 mg Tablet 60's if you are trying to become pregnant or if you have any concerns regarding this.

    Tofaciz 5 mg Tablet 60's affects the immune system and might lower the ability of the immune system to fight infections. Inform your doctor if you have an active infection, if you have a condition that increases the chance of having infections, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids.

    PRODUCT SUBSTITUTES

    Tofaciz 5 mg Tablet 60's

    Disclaimer

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    (Inclusive of all taxes)

    Provide Delivery Location

    Bottle

    1

    60 Tablet in 1 Bottle