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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Tonact EZ 10 Tablet

Tonact EZ 10 Tablet is a prescription oral medicine used to lower high levels of cholesterol and triglycerides in the blood. It helps decrease bad cholesterol (LDL) and fats, while increasing good cholesterol (HDL). By managing these lipid levels, this medicine plays an important role in reducing your risk of heart attacks and strokes.

For the best results, you must take Tonact EZ 10 Tablet consistently every day, exactly as prescribed by your healthcare provider. You can take this tablet with or without food, but taking it at the same time each day helps build a regular routine. Combining this treatment with a heart-healthy diet and regular physical activity will significantly improve your cholesterol levels.

Most people tolerate this medication well, but some may experience mild side effects like joint pain, diarrhoea, or muscle aches. If you develop unexplained muscle pain, tenderness, or weakness, especially if accompanied by a fever, you should contact your doctor immediately. These symptoms could be a sign of a rare but serious muscle condition, so prompt medical advice is essential.

Talk to your doctor before starting Tonact EZ 10 Tablet if you have a history of liver disease, kidney problems, or thyroid disorders. Do not take this if you currently have active liver disease or unexplained abnormal liver test results. Pregnant or breastfeeding women must not take this medication, as it can harm the developing baby.

This medicine can interact with certain other treatments, such as specific antibiotics, antifungals, or blood thinners, which can increase the risk of muscle damage. It is also important to avoid drinking large amounts of alcohol, as this can increase your risk of liver damage. If you are an elderly individual, your doctor may want to monitor your kidney and liver function more closely while you take this medicine.

Uses of Tonact EZ 10 Tablet

Tonact EZ 10 Tablet is used in the treatment of hyperlipidemia, also known as high cholesterol. The detailed uses of Tonact EZ 10 Tablet are as follows:

  • High cholesterol (Hypercholesterolemia): Tonact EZ 10 Tablet helps lower high levels of low-density lipoprotein (LDL) cholesterol and total cholesterol in the blood when diet and exercise alone are not enough.
  • Mixed lipid levels (Mixed Dyslipidemia): Tonact EZ 10 Tablet reduces elevated levels of triglycerides (fats) and bad cholesterol while helping to raise good cholesterol (HDL) levels.
  • Prevention of cardiovascular events: For patients with heart disease or those at high risk, Tonact EZ 10 Tablet lowers the chances of experiencing a heart attack, stroke, or needing medical procedures to improve blood flow to the heart.

Key Benefits

Tonact EZ 10 Tablet helps lower high cholesterol levels and supports healthier blood lipid levels. By providing effective cholesterol management, it helps protect your heart and blood vessels over the long term.

Benefits may include:

  • Helps reduce bad cholesterol and triglycerides in the blood.
  • Helps prevent the accumulation of fatty deposits in the arteries.
  • Promotes smoother circulation by helping keep blood vessels healthier.
  • Supports protection against serious heart-related complications.
  • Helps lower the chance of stroke associated with high cholesterol levels.
Side effects of Tonact EZ 10 Tablet
  • To improve liver health and aid in the removal of toxins, drink lots of water.
  • Alcohol consumption should be reduced or stopped because it can raise ALT levels and impair liver function.
  • Consume a well-rounded diet full of whole grains, fruits, and vegetables. Limit items that strain the liver, such as processed, fatty, or fried foods.
  • You can monitor your ALT levels and make treatment modifications with the support of routine blood tests.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.

Directions for Use

  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can alter how the medicine is absorbed in your body.
  • You can take this medication with or without food.
  • Try to take your dose at the same time every day to maintain a steady level of the medicine in your body.
  • Always follow your doctor's exact instructions regarding your schedule. Do not alter your dose or stop taking this medication without consulting your healthcare provider first.

How Tonact EZ 10 Tablet Works

Tonact EZ 10 Tablet contains two active ingredients that work together to lower your blood cholesterol levels. • Atorvastatin: It works directly in the liver. It blocks a specific enzyme (HMG-CoA reductase) that the liver needs to produce cholesterol, which significantly reduces the amount of cholesterol circulating in your bloodstream. • Ezetimibe: It works in the small intestine. It blocks the absorption of cholesterol from the food you eat and from the bile produced by your body.
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Alcohol

Caution

Do not drink too much while taking this medicine. Drinking a lot of alcohol, you may be more likely to get muscle and liver side effects.

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Pregnancy

Caution

Tonact EZ 10 Tablet contains atorvastatin, which is not recommended during pregnancy. Contact your doctor before taking Tonact EZ 10 Tablet .

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Breast Feeding

Consult your doctor

Breastfeeding is not recommended while taking Tonact EZ 10 Tablet because the safety of this medication passing into breast milk is unknown. Contact your doctor before taking Tonact EZ 10 Tablet .

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Driving

Safe

Tonact EZ 10 Tablet has negligible influence on the ability to drive and use machines.

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Liver

Caution

Tonact EZ 10 Tablet to be taken with caution, especially if you have a history of liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Tonact EZ 10 Tablet to be taken with caution, especially if you have a history of kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Tonact EZ 10 Tablet is not recommended for children as the safety and efficacy of Tonact EZ 10 Tablet has not been established.

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Heart

Safe if prescribed

Tonact EZ 10 Tablet is generally safe for heart patients. However, medical supervision is essential to monitor for side effects like liver or muscle issues.

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Geriatrics

Caution

Tonact EZ 10 Tablet can be used in geriatric patients, but with caution due to increased sensitivity to side effects like muscle pain, liver enzyme changes, or drug interactions. Medical supervision is essential to ensure safe and effective cholesterol management in older adults.

What if I have taken an overdose of Tonact EZ 10 Tablet

In case of an accidental overdose, seek immediate medical attention or contact a local poison control centre. Do not wait for symptoms to appear.

Diet & Lifestyle Advise

  • Eat a heart-healthy diet: Focus on soluble fibre-rich foods like oats, beans, lentils, and fruits, which help lower cholesterol. Limit saturated fats and trans fats found in fried foods, butter, and fatty meats.
  • Incorporate healthy fats: Use plant-based oils like olive or canola oil, and consume omega-3 fatty acids from fish (like salmon or mackerel) or flaxseeds.
  • Engage in regular exercise: Aim for at least 150 minutes of moderate-intensity aerobic exercise, such as brisk walking, swimming, or cycling, every week to help raise your good cholesterol.
  • Limit alcohol intake: Restrict your alcohol consumption, as excessive drinking can increase your triglyceride levels and place extra stress on your liver.
  • Avoid smoking: Quitting smoking helps improve your HDL cholesterol levels and significantly reduces your overall risk of cardiovascular disease.

Have a query?

How Soon It Starts Working

  • The time required for Tonact EZ 10 Tablet to start to work: Tonact EZ 10 Tablet ideally shows its action within 1 to 2 hours after administration.
  • The time for which the effects of Tonact EZ 10 Tablet last: The effect of Tonact EZ 10 Tablet lasts for 2 days.

What if you forget to take Tonact EZ 10 Tablet

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Avoid during pregnancy: Do not take this medicine if you are pregnant, planning to become pregnant, or think you may be pregnant. Use reliable birth control while taking this medication and contact your doctor immediately if you become pregnant.
  • Avoid grapefruit: Do not eat grapefruit or drink grapefruit juice while taking this medicine. Grapefruit can increase the amount of the medicine in your body and may raise the risk of side effects.
  • Watch for muscle problems: Contact your doctor if you develop unexplained muscle pain, tenderness, weakness, cramps, or unusual tiredness. These symptoms may need medical attention.
  • Check liver health: Your doctor may order blood tests before and during treatment to monitor your liver function. Attend all recommended check-ups and report symptoms such as yellowing of the skin, dark urine, or severe fatigue.
  • Tell healthcare providers: Inform your surgeon, dentist, or any other healthcare professional that you are taking this medicine before any procedure or surgery. This helps them plan your care safely.

Drug-Drug Interactions

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Drug-Drug Interaction:

  • Antivirals (e.g., ritonavir): Taking these medicines alongside Tonact EZ 10 Tablet may increase the amount of the medicine in your body and may increase the risk of severe muscle damage.
  • Antifungals (e.g., ketoconazole): May increase the amount of the medicine in your body and may increase the risk of severe muscle damage.
  • Antibiotics (e.g., erythromycin): May increase the amount of the medicine in your body and may increase the risk of severe muscle damage.
  • Fibrates/Lipid-lowering Medications (e.g., fenofibrate, gemfibrozil): Taking these medicines alongside Tonact EZ 10 Tablet may increase the risk of muscle problems and liver-related side effects.
  • Niacin (Vitamin B3): Taking niacin alongside Tonact EZ 10 Tablet may increase the risk of muscle problems and liver-related side effects.
  • Blood Thinners (e.g., warfarin): These medicines may affect blood clotting when taken with Tonact EZ 10 Tablet and may require closer monitoring.

Drug-Food Interaction:

  • Grapefruit and grapefruit juice: Consuming grapefruit or grapefruit juice while taking Tonact EZ 10 Tablet may increase the amount of the medicine in your body and may increase the risk of side effects.

Drug-Disease Interaction:

  • Active liver disease: Do not take this medicine if you have active liver disease or unexplained, elevated liver enzymes, as it can worsen liver damage.
  • Kidney impairment: If you have severe kidney problems, your doctor may need to monitor you closely to prevent side effects.
  • Thyroid issues (Hypothyroidism): Underactive thyroid function should be managed before starting this medicine, as untreated thyroid issues can increase the risk of muscle-related side effects.
Severe

Drug-Drug Interactions

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Severe
How does the drug interact with Tonact EZ 10 Tablet:
Using Tonact EZ 10 Tablet together with cerivastatin can increase the risk of side effects (liver damage and rhabdomyolysis - a condition that involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
There may be a possibility of interaction between Tonact EZ 10 Tablet and Cerivastatin, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - like feeling achy, weak, or having a fever - it's a good idea to reach out to your doctor right away. Other symptoms to watch out for include dark urine, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, or bleeding. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tonact EZ 10 Tablet:
Taking Tonact EZ 10 Tablet and ciclosporin can significantly increase the blood levels of atorvastatin, that may increase the risk of side effects such as liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Tonact EZ 10 Tablet and cyclosporine together can result in an interaction; it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light colored stools, or yellowing of the skin or eyes, you should consult a doctor. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Tonact EZ 10 Tablet:
Using conivaptan together with Tonact EZ 10 Tablet may significantly increase the blood levels of atorvastatin that may increase the risk of side effects such as liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Tonact EZ 10 Tablet with Conivaptan together can result in an interaction, but it can be taken if a doctor has advised it. You should also seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Tonact EZ 10 Tablet:
Using tipranavir together with Tonact EZ 10 Tablet may significantly increase the blood levels of atorvastatin that may increase the risk of side effects such as liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Tipranavir and Tonact EZ 10 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tonact EZ 10 Tablet:
Taking Tonact EZ 10 Tablet with atazanavir may drastically elevate atorvastatin levels in the blood, that may increase the risk of side effects such as liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Tonact EZ 10 Tablet with atazanavir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Tonact EZ 10 Tablet:
Taking Temsirolimus and Tonact EZ 10 Tablet can increase blood levels of cholesterol and triglycerides.

How to manage the interaction:
There may be a possibility of interaction between Tonact EZ 10 Tablet and Temsirolimus, but it can be taken if prescribed by a doctor. If you are taking sirolimus or temsirolimus along with your cholesterol-lowering medications, it is important to regularly check blood cholesterol and triglyceride levels with a doctor. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Tonact EZ 10 Tablet:
Coadministration of Tonact EZ 10 Tablet with Lomitapide may increase the blood levels of lomitapide that may increase the risk of side effects such as liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
There may be a possibility of interaction between Tonact EZ 10 Tablet and Lomitapide, but it can be taken if prescribed by a doctor. Seek immediate medical attention if you develop signs and symptoms of liver damage such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Tonact EZ 10 Tablet:
Taking Tonact EZ 10 Tablet with nelfinavir may considerably raise atorvastatin levels in the blood that may increase the risk of side effects such as liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Tonact EZ 10 Tablet and Nelfinavir together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Tonact EZ 10 Tablet:
Taking Tonact EZ 10 Tablet with rifampicin can decrease the blood levels of atorvastatin, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Tonact EZ 10 Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Tonact EZ 10 Tablet:
Taking Tonact EZ 10 Tablet and Pravastatin can significantly increase the blood levels of atorvastatin that may increase the risk of side effects such as liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Tonact EZ 10 Tablet with Pravastatin can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, fever, dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light colored stools, or yellowing of the skin or eyes, you should consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTILIPEMICS]

FAQs

Tonact EZ 10 Tablet is used to treat high cholesterol levels.

You should avoid alcohol while taking Tonact EZ 10 Tablet since it may increase your risk of getting side effects in the liver. Talk with your doctor if you have any trouble.

Tonact EZ 10 Tablet is a medication that helps lower cholesterol levels. It works in two ways: by reducing the amount of cholesterol produced in the liver and blocking the absorption of cholesterol from food in the intestines. This medication helps significantly reduce harmful cholesterol levels, which can lower the risk of heart disease.

Yes. Muscle weakness can be a long-term side effect of Tonact EZ 10 Tablet . You may have muscle fatigue or muscle pain which affects your daily activity. Try to contact a doctor if you have muscle weakness or fatigue.

No, there is no evidence that Tonact EZ 10 Tablet is addictive. It is used for lowering cholesterol levels.

Tonact EZ 10 Tablet contains Atorvastatin, which can cause a slight increase in blood sugar levels. If you already have type 2 diabetes please consult your doctor. Your doctor may adjust the dosage of Tonact EZ 10 Tablet .

Increase your daily diet with fibre, fruits, vegetables, whole grains, and fish, and cut saturated fat as well. Stop smoking and drinking, and try to work out every day as well.

No, you should not stop taking Tonact EZ 10 Tablet without consulting your doctor. Please take advice from the doctor before quitting.

Tonact EZ 10 Tablet is generally well-tolerated, with most individuals experiencing transient and manageable adverse effects. Commonly reported side effects include gastrointestinal disturbances (nausea, stomach pain, and constipation), musculoskeletal pain, headache, and minor elevations in blood glucose and liver enzyme levels. These effects typically resolve over time. However, if any adverse reactions persist or worsen, it is essential to consult a healthcare professional for proper evaluation and guidance.

Tonact EZ 10 Tablet is a highly effective treatment option when used as directed by your healthcare provider. It is crucial to adhere to the prescribed dosage and treatment duration to achieve optimal results. Completing the entire course of therapy is essential, as premature discontinuation may lead to the return or worsening of symptoms. By following your doctor's instructions, you can maximise the benefits of Tonact EZ 10 Tablet and effectively manage your condition.

No, it is not recommended for use in patients with active liver disease. Therefore, inform your doctor if you have any liver diseases before prescribing Tonact EZ 10 Tablet . Your doctor will assess your condition and determine whether this medication is safe and appropriate for you.

Diarrhoea is a potential side effect of Tonact EZ 10 Tablet , although it occurs in a minority of individuals. If you experience diarrhoea while taking this medication, it is essential to prioritise hydration by drinking plenty of fluids, such as water, clear broths, and electrolyte-rich beverages. If diarrhoea persists or becomes severe, consult your healthcare provider promptly for guidance and support.

No, you must not take Tonact EZ 10 Tablet if you are pregnant or planning to become pregnant. It can cause serious harm to a developing baby. If you suspect you are pregnant while taking this medicine, stop taking it and talk to your doctor immediately.

Yes, you should avoid eating grapefruit or drinking grapefruit juice. Grapefruit can increase the amount of this medication in your blood, which raises your risk of developing serious side effects. For more dietary advice, talk to your doctor or pharmacist.

Tonact EZ 10 Tablet starts working to lower your lipid levels within 1 to 2 weeks, but it may take up to 4 weeks to see the full therapeutic effect. Your doctor will likely perform blood tests after a few weeks to monitor your progress. Talk to your doctor to understand your specific treatment timeline.

Yes, muscle pain is a known, though relatively uncommon, side effect of this medication. If you experience unexplained muscle pain, tenderness, or weakness, especially if you also have a fever or feel generally unwell, contact your doctor right away. Talk to your doctor about any unusual muscle symptoms.

You can take Tonact EZ 10 Tablet at any time of day, with or without food. However, it is best to take it at the same time every day to maintain consistent levels in your body. Talk to your doctor or pharmacist to determine the best schedule for your daily routine.

If you experience mild side effects like a mild stomach upset or a headache, they may resolve on their own. However, if these symptoms persist or if you experience serious symptoms like severe muscle pain or yellowing of the skin, you should contact your healthcare provider immediately. Talk to your doctor or pharmacist for advice on managing side effects.

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Country of origin

India

Manufacturer/Marketer address

3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Other Info - TON0013
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