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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tonact EZ 10 Tablet

Tonact EZ 10 Tablet is primarily used to treat high cholesterol levels. Dyslipidemia (high cholesterol level) is the deposition of unhealthy levels of fats (lipids) in the blood.

Tonact EZ 10 Tablet contains Atorvastatin and Ezetimibe. Atorvastatin helps to decrease the production of cholesterol, and Ezetimibe prevents the absorption of cholesterol from the intestines.

You may experience nausea, stomach pain, constipation, muscle pain, headache, increased glucose level in the blood, and increased liver enzymes. If the side effects are persistent, reach out to your doctor.

Do not take Tonact EZ 10 Tablet if you are allergic to any of its components. Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Inform your doctor about all the medications you are taking and pre-existing medical conditions.

Uses of Tonact EZ 10 Tablet

Tonact EZ 10 Tablet is used in the treatment of hyperlipidemia, also known as high cholesterol. The detailed uses of Tonact EZ 10 Tablet are as follows:

  • Hyperlipidemia: Tonact EZ 10 Tablet reduces high levels of total cholesterol, LDL (bad cholesterol), and triglycerides while increasing HDL (good cholesterol).
  • Heart attack prevention: Tonact EZ 10 Tablet lowers the risk of heart attacks by lowering cholesterol levels.
  • Stroke prevention: Tonact EZ 10 Tablet reduces the chance of stroke by lowering cholesterol levels and preventing blood clots.
  • Cardiovascular risk reduction: Tonact EZ 10 Tablet lowers the risk of heart-related complications by controlling lipid levels.

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Directions for Use

  • Take Tonact EZ 10 Tablet with or without food, or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Tonact EZ 10 Tablet helps in the treatment of high cholesterol, especially for heart patients, when initial dietary measures fail to lower cholesterol.
  • It helps lower the bad cholesterol (LDL) and increases the level of good cholesterol (HDL).
  • Tonact EZ 10 Tablet also reduces the amount of fat or cholesterol deposition (plaque) in the heart arteries, thereby lowering the risk of future heart attacks or strokes.

How Tonact EZ 10 Tablet Works

Tonact EZ 10 Tablet is a combination of two medicines: Atorvastatin (HMG-CoA reductase inhibitors (statins)) and Ezetimibe (sterol absorption inhibitor). Atorvastatin helps to decrease the production of cholesterol that may build up on the blood vessels (arteries) of the heart, brain, and other parts of the body. On the other hand, Ezetimibe is a cholesterol absorption inhibitor that prevents the absorption of cholesterol from the intestines. Together, they decrease cholesterol in your body.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Tonact EZ 10 Tablet
  • To improve liver health and aid in the removal of toxins, drink lots of water.
  • Alcohol consumption should be reduced or stopped because it can raise ALT levels and impair liver function.
  • Consume a well-rounded diet full of whole grains, fruits, and vegetables. Limit items that strain the liver, such as processed, fatty, or fried foods.
  • You can monitor your ALT levels and make treatment modifications with the support of routine blood tests.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.

What if I have taken an overdose of Tonact EZ 10 Tablet

Do not take more than the prescribed dose of Tonact EZ 10 Tablet as it may cause severe side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Avoid taking Tonact EZ 10 Tablet if you are allergic to any of the components in Tonact EZ 10 Tablet .
  • Do not take Tonact EZ 10 Tablet if you have a previous heart attack or stroke caused by bleeding in the brain, have hypothyroidism, or a muscle disorder (fibromyalgia).
  • Inform your doctor if you have liver, kidney or lung problems.
  • Tonact EZ 10 Tablet is not safe for children as the safety and efficacy of Tonact EZ 10 Tablet in children have not been established.
  • If you have been told by your doctor that you have an intolerance to some sugars, talk to your doctor before taking Tonact EZ 10 Tablet .
  • If you are pregnant, planning to become pregnant or breastfeeding, consult your doctor.
  • Let your doctor know if you are taking any other medicines.

Drug-Drug Interactions

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AtorvastatinSaquinavir
Severe

Drug-Drug Interactions

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How does the drug interact with Tonact EZ 10 Tablet:
Taking Tonact EZ 10 Tablet with Posaconazole can increase the blood levels of Tonact EZ 10 Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Tonact EZ 10 Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AtorvastatinSaquinavir
Severe
How does the drug interact with Tonact EZ 10 Tablet:
Taking Tonact EZ 10 Tablet with saquinavir may significantly enhance Tonact EZ 10 Tablet levels in the blood. This can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury0.

How to manage the interaction:
Co- administration of Tonact EZ 10 Tablet with saquinavir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinClofibrate
Severe
How does the drug interact with Tonact EZ 10 Tablet:
Using clofibrate together with Tonact EZ 10 Tablet can increase the risk of side effects.

How to manage the interaction:
Co-administration of Clofibrate with Tonact EZ 10 Tablet can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and contact a doctor right away if you notice any of these signs - liver problems, muscle damage, kidney problems, complications, pain, weakness, fever, dark urine, chills, joint pain, swelling, bruising, rash, itching, loss of appetite, tiredness, feeling sick, throwing up, or bleeding. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tonact EZ 10 Tablet:
Taking Tonact EZ 10 Tablet with rifampicin can decrease the blood levels of Tonact EZ 10 Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Tonact EZ 10 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AtorvastatinLomitapide
Severe
How does the drug interact with Tonact EZ 10 Tablet:
Coadministration of Tonact EZ 10 Tablet with Lomitapide may increase the blood levels of lomitapide.

How to manage the interaction:
There may be a possibility of interaction between Tonact EZ 10 Tablet and Lomitapide, but it can be taken if prescribed by a doctor. Seek immediate medical attention if you develop signs and symptoms of liver damage such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tonact EZ 10 Tablet:
Combining Tonact EZ 10 Tablet with atazanavir may drastically elevate Tonact EZ 10 Tablet levels in the blood. This can raise the chance of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Tonact EZ 10 Tablet with atazanavir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Tonact EZ 10 Tablet:
Taking Tonact EZ 10 Tablet and ciclosporin can significantly increase the blood levels of Tonact EZ 10 Tablet.

How to manage the interaction:
Taking Tonact EZ 10 Tablet and cyclosporine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light colored stools, or yellowing of the skin or eyes, you should consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Tonact EZ 10 Tablet:
Taking Tonact EZ 10 Tablet with indinavir may considerably raise Tonact EZ 10 Tablet levels in the blood.

How to manage the interaction:
Taking Tonact EZ 10 Tablet and indinavir together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinFosamprenavir
Severe
How does the drug interact with Tonact EZ 10 Tablet:
Using Tonact EZ 10 Tablet together with fosamprenavir may significantly increase the blood levels of Tonact EZ 10 Tablet.

How to manage the interaction:
Although there is a possible interaction between Tonact EZ 10 Tablet and Fosamprenavir, you can take these medicines together if prescribed by a doctor. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without talking to a doctor.
How does the drug interact with Tonact EZ 10 Tablet:
Using Tonact EZ 10 Tablet with ketoconazole, may raise the chance of side effects (liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Tonact EZ 10 Tablet with ketoconazole can result in an interaction, it can be taken if a doctor has recommended it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try aromatherapy, yoga, and meditation to help relax your body and mind.
  • Try to do breathing exercises to get more oxygen.
  • Eat a healthy diet, especially rich in soluble fibre like beans, legumes, whole grains, flax, apples, and citrus fruits.
  • Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol in a short span of time. Foods like avocados, olive oil, fatty fish, and nuts contain lots of heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
  • Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, and fish, and low in red meat and most dairy.
  • Try to give priority to more fruits and veggies in your daily meals, as these contain antioxidants that help to lower LDL
  • Minimise the intake of added sugar. The American Heart Association (ADA) recommends that one should not eat more than 100 calories (25 grams) of added sugar for women and children, and no more than 150 calories (37.5 grams) for men every day.
  • The American Heart Association recommends that the intake of sodium chloride (table salt) should not exceed 2,300 mg per day as part of a healthy eating pattern.
  • As a precautionary measure, do not consume alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANTILIPEMICS
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Alcohol

Caution

Do not drink too much while taking this medicine. Drinking a lot of alcohol, you may be more likely to get muscle and liver side effects.

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Pregnancy

Caution

Tonact EZ 10 Tablet contains atorvastatin, which is not recommended during pregnancy. Contact your doctor before taking Tonact EZ 10 Tablet .

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Breast Feeding

Consult your doctor

Breastfeeding is not recommended while taking Tonact EZ 10 Tablet because the safety of this medication passing into breast milk is unknown. Contact your doctor before taking Tonact EZ 10 Tablet .

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Driving

Safe

Tonact EZ 10 Tablet has negligible influence on the ability to drive and use machines.

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Liver

Caution

Tonact EZ 10 Tablet to be taken with caution, especially if you have a history of liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Tonact EZ 10 Tablet to be taken with caution, especially if you have a history of kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Tonact EZ 10 Tablet is not recommended for children as the safety and efficacy of Tonact EZ 10 Tablet has not been established.

FAQs

Tonact EZ 10 Tablet is used to treat high cholesterol levels.

You should avoid alcohol while taking Tonact EZ 10 Tablet since it may increase your risk of getting side effects in the liver. Talk with your doctor if you have any trouble.

Tonact EZ 10 Tablet is a medication that helps lower cholesterol levels. It works in two ways: by reducing the amount of cholesterol produced in the liver and blocking the absorption of cholesterol from food in the intestines. This medication helps significantly reduce harmful cholesterol levels, which can lower the risk of heart disease.

Yes. Muscle weakness can be a long-term side effect of Tonact EZ 10 Tablet . You may have muscle fatigue or muscle pain which affects your daily activity. Try to contact a doctor if you have muscle weakness or fatigue.

No, there is no evidence that Tonact EZ 10 Tablet is addictive. It is used for lowering cholesterol levels.

Tonact EZ 10 Tablet contains Atorvastatin, which can cause a slight increase in blood sugar levels. If you already have type 2 diabetes please consult your doctor. Your doctor may adjust the dosage of Tonact EZ 10 Tablet .

Increase your daily diet with fibre, fruits, vegetables, whole grains, and fish, and cut saturated fat as well. Stop smoking and drinking, and try to work out every day as well.

No, you should not stop taking Tonact EZ 10 Tablet without consulting your doctor. Please take advice from the doctor before quitting.

Tonact EZ 10 Tablet is generally well-tolerated, with most individuals experiencing transient and manageable adverse effects. Commonly reported side effects include gastrointestinal disturbances (nausea, stomach pain, and constipation), musculoskeletal pain, headache, and minor elevations in blood glucose and liver enzyme levels. These effects typically resolve over time. However, if any adverse reactions persist or worsen, it is essential to consult a healthcare professional for proper evaluation and guidance.

Tonact EZ 10 Tablet is a highly effective treatment option when used as directed by your healthcare provider. It is crucial to adhere to the prescribed dosage and treatment duration to achieve optimal results. Completing the entire course of therapy is essential, as premature discontinuation may lead to the return or worsening of symptoms. By following your doctor's instructions, you can maximise the benefits of Tonact EZ 10 Tablet and effectively manage your condition.

No, it is not recommended for use in patients with active liver disease. Therefore, inform your doctor if you have any liver diseases before prescribing Tonact EZ 10 Tablet . Your doctor will assess your condition and determine whether this medication is safe and appropriate for you.

Diarrhoea is a potential side effect of Tonact EZ 10 Tablet , although it occurs in a minority of individuals. If you experience diarrhoea while taking this medication, it is essential to prioritise hydration by drinking plenty of fluids, such as water, clear broths, and electrolyte-rich beverages. If diarrhoea persists or becomes severe, consult your healthcare provider promptly for guidance and support.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - TON0121

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