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compositionComposition:FERRIC CARBOXYMALTOSE-500MG
prescription
Prescription Medicine
info
Tufehart 500 mg Injection 10 ml

Tufehart 500 mg Injection is used to treat iron deficiency anaemia. It contains ferric carboxymaltose, which acts as a source of iron and helps in the transportation of oxygen throughout the body and the production of red blood cells. In some cases, this medicine may cause side effects such as nausea, flushing, dizziness, high blood pressure, and low levels of phosphorus in the blood. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

FERRIC CARBOXYMALTOSE-500MG

Manufacturer/Marketer :

Alembic Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Tufehart 500 mg Injection

Tufehart 500 mg Injection belongs to the group of anti-anaemic medicines used to treat iron deficiency anaemia in patients who are intolerant to oral iron preparations, have non-dialysis dependant chronic kidney disease, or require a quick build-up of iron stores. Iron deficiency anaemia (lack of red blood cells caused by too little iron in the body) is a condition in which the body does not have enough red blood cells for carrying adequate oxygen to various body tissues.
 
Tufehart 500 mg Injection contains ‘ferric carboxymaltose’, which acts as a source of iron and helps in the transportation of oxygen throughout the body and the production of red blood cells. Thereby, Tufehart 500 mg Injection helps in treating anaemia. Tufehart 500 mg Injection helps various vital processes in the body.
 
Tufehart 500 mg Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side effects such as nausea, flushing, dizziness, high blood pressure, and low levels of phosphorus in the blood. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Let your doctor know if you are taking any prescription, non-prescription drugs, or herbal products before starting Tufehart 500 mg Injection. If you are known to be allergic to any of the components in Tufehart 500 mg Injection, please inform your doctor. Consult a doctor before taking Tufehart 500 mg Injection if you are pregnant or breastfeeding. Tufehart 500 mg Injection is not recommended for children below 14 years as safety and effectiveness have not been established.

Uses of Tufehart 500 mg Injection

Tufehart 500 mg Injection is used in the treatment of Iron deficiency anaemia. The detailed uses of Tufehart 500 mg Injection are as follows:

  • < strong>Treatment of Iron Deficiency Anaemia:Tufehart 500 mg Injection is primarily used for managing iron deficiency anaemia in patients who cannot tolerate or have not responded adequately to oral iron therapies.
  • Supplementation for Chronic Kidney Disease Patients: Tufehart 500 mg Injection is beneficial for individuals with chronic kidney disease, addressing anaemia caused by reduced erythropoietin production and impaired iron metabolism.
  • Support During Pregnancy:Pregnant women diagnosed with or at risk of iron deficiency anaemia can use Tufehart 500 mg Injection to maintain adequate iron levels for their health and the proper development of the fetus.
  • Boosting Iron Levels Pre-Surgery:Tufehart 500 mg Injection may be administered to patients before surgeries, especially those at higher risk of bleeding, to enhance iron stores and minimise anaemia-related complications.

Key Benefits

Tufehart 500 mg Injection belongs to the group of anti-anaemic medicines used to treat iron deficiency anaemia in patients who are intolerant to oral iron preparations and have non-dialysis dependant chronic kidney disease. Tufehart 500 mg Injection contains ‘ferric carboxymaltose’, which acts as a source of iron and helps in the transportation of oxygen throughout the body and the production of red blood cells. Thereby, Tufehart 500 mg Injection helps in treating anaemia. Iron is necessary for various vital processes in the body.

Side effects of Tufehart 500 mg Injection 10 ml
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Avoid trigger foods that can cause allergic reactions, such as nuts, shellfish, or dairy products.
  • Keep a food diary to track potential food allergens.
  • Include omega-3 rich foods like salmon and walnuts to reduce inflammation.
  • Wear loose, comfortable clothing made from soft fabrics like cotton.
  • Apply cool compresses or take cool baths to reduce itching.
  • Use gentle soaps and avoid harsh skin products.
  • Reduce stress through relaxation techniques like meditation or deep breathing.

Directions for Use

  • Your doctor will determine the dosage and timing of Tufehart 500 mg Injection based on your health condition. Typically, it is given once a week.
  • Tufehart 500 mg Injection will be administered by a qualified healthcare professional in a hospital setting.
  • Do not self-administer it.

How Tufehart 500 mg Injection Works

Tufehart 500 mg Injection contains ‘ferric carboxymaltose’, which acts as a source of iron and helps in the transportation of oxygen throughout the body and the production of red blood cells. Thereby, Tufehart 500 mg Injection helps in treating anaemia. Tufehart 500 mg Injection helps various vital processes in the body.
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Alcohol

Caution

It is unknown if alcohol interacts with Tufehart 500 mg Injection, so please consult a doctor.

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Pregnancy

Caution

Consult your doctor if you are pregnant. Your doctor will decide if Tufehart 500 mg Injection can be taken during pregnancy or not.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding. Your doctor will decide if Tufehart 500 mg Injection can be taken by breastfeeding mothers or not.

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Driving

Safe if prescribed

Tufehart 500 mg Injection is unlikely to affect your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Tufehart 500 mg Injection is not recommended for children below 14 years as safety and effectiveness have not been established.

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Heart

Caution

Tufehart 500 mg Injection should be administered with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before receiving Tufehart 500 mg Injection.

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Geriatrics

Caution

Tufehart 500 mg Injection should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Tufehart 500 mg Injection

It is unlikely to overdose on parenteral medication as it is administered by a healthcare professional. However, seek medical attention if you experience symptoms of overdose such as pain, wheezing, cough, shortness of breath, weight loss, or coughing up blood.

Diet & Lifestyle Advise

  • Follow a well-balanced diet.

  • Eat a healthy diet, especially green leafy vegetables, and do regular physical exercise.

  • Limit junk food and stick to freshly prepared home-cooked meals.

  • Increase your intake of fruits, especially fruits rich in iron like pomegranate, and citrus fruits.

  • Drink plenty of fluids to keep yourself hydrated.

  • Include leafy vegetables, poultry, seafood, beans, nuts, seeds, meat and fortified food in your diet.

Have a query?

How Soon It Starts Working

The time required for Tufehart 500 mg Injection to start to work: The time required for Tufehart 500 mg Injection to show its action is unknown. The time for which the effects of Tufehart 500 mg Injection last: The duration of action for Tufehart 500 mg Injection is clinically unknown.

What if you forget to take Tufehart 500 mg Injection

If you miss a dose of Tufehart 500 mg Injection, contact your doctor; they will provide guidance on rescheduling the missed dose or adjusting your treatment plan based on your health status. Do not receive a double dose without consulting your doctor.

Storage

• Store in a cool and dry place away from sunlight.• Keep Tufehart 500 mg Injection out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Do not take Tufehart 500 mg Injection if you are allergic to any of its components, if you have anaemia not caused by iron deficiency, iron overload (excess iron in the body), or disturbances in iron utilisation. Inform your doctor if you have systemic lupus erythematosus, rheumatoid arthritis, severe asthma, eczema, infection, low phosphorus levels, high blood pressure, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Tufehart 500 mg Injection is not recommended for children below 14 years as safety and effectiveness have not been established. Let your doctor know if you are taking any prescription, non-prescription drugs, or herbal products before starting Tufehart 500 mg Injection.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Oral iron preparations become less effective when taken along with Tufehart 500 mg Injection.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have iron storage or absorption disease, high blood pressure, or hypophosphatemia (low phosphate levels).

FERRIC CARBOXYMALTOSEEnalapril
Severe
FERRIC CARBOXYMALTOSEDimercaprol
Severe

Drug-Drug Interactions

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FERRIC CARBOXYMALTOSEEnalapril
Severe
How does the drug interact with Tufehart 500 mg Injection 10 ml:
Taking Enalapril and Ferric Carboxymaltoside increases the side effects of enalapril.

How to manage the interaction:
Although taking Enalapril with Tufehart 500 mg Injection 10 ml may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience dizziness, lightheadedness, headache, blurred vision, or chest pain, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
FERRIC CARBOXYMALTOSEDimercaprol
Severe
How does the drug interact with Tufehart 500 mg Injection 10 ml:
Coadministration of Dimercaprol with Tufehart 500 mg Injection 10 ml can increase the risk of developing kidney problems.

How to manage the interaction:
Although there is an interaction between Tufehart 500 mg Injection 10 ml and dimercaprol, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[IRON PREPARATIONS]

FAQs

Tufehart 500 mg Injection is used to treat iron deficiency anaemia in patients who are intolerant to oral iron preparations, have non-dialysis dependant chronic kidney disease, or require a quick build-up of iron stores.
Tufehart 500 mg Injection acts as a source of iron and helps in the transportation of oxygen throughout the body and the production of red blood cells. Thereby, Tufehart 500 mg Injection helps in treating anaemia.
Tufehart 500 mg Injection might cause hypophosphatemia (low phosphorus levels). Inform your doctor if you experience symptoms such as severe tiredness, bone or muscle pain, as these could be a sign of low phosphorus levels. Regular monitoring of phosphorus levels whilst on treatment with Tufehart 500 mg Injection is advised.
Consult your doctor if you have hypertension as Tufehart 500 mg Injection might cause high blood pressure, sometimes accompanied by dizziness, facial flushing, or nausea. Your doctor will monitor for signs and symptoms of hypertension while on treatment with Tufehart 500 mg Injection.
Tufehart 500 mg Injection might cause the stools to appear darker than usual; this is due to the elimination of unabsorbed iron. Do not worry, as it is normal and harmless. Consult a doctor if this bothers you or if you notice blood in your stools.
Oral iron preparations will be less effective when taken along with Tufehart 500 mg Injection. Inform your doctor if you are taking oral iron preparations or any supplements.
Iron deficiency anaemia occurs when the body's iron stores are too low to support the production of haemoglobin, a crucial protein in red blood cells that carries oxygen to the body's tissues. As a result, the body may not have enough healthy red blood cells or haemoglobin, leading to anaemia. Anaemia can cause symptoms like fatigue, weakness, pale skin, and shortness of breath.
Iron is a vital nutrient that can be sourced from a diverse range of foods. Animal-based options like red meat, poultry, and seafood are high in iron, with organ meats like liver and kidney being particularly rich. Plant-based sources include legumes like lentils, beans, and peas and leafy greens such as spinach, kale, and collard greens. Nuts and seeds like pumpkin, sesame, and sunflower are also good sources, along with fortified cereals and dried fruits like apricots, prunes, and raisins. Whole grains like quinoa, brown rice, and whole-wheat bread contain iron, too. Additionally, certain mushrooms like shiitake and oyster and cooked veggies like broccoli, Brussels sprouts, and sweet potatoes are iron-rich. Eating a varied diet that includes these foods can help ensure you meet your daily iron requirements.
Tufehart 500 mg Injection is usually safe to take during pregnancy. It's an iron supplement that helps with iron deficiency and anaemia, which are common in pregnant women. If you have any concerns, talk to your doctor. They'll check your needs and ensure the benefits outweigh any risks.
The duration of taking Tufehart 500 mg Injection depends on the individual's health condition and response to the medication. Always consult your healthcare provider for personalized advice on taking Tufehart 500 mg Injection. They will assess your needs and provide guidance on the appropriate duration of treatment.
Tufehart 500 mg Injection is a highly effective and well-tolerated iron supplement, particularly suited for individuals who struggle to absorb iron from food or have elevated iron requirements. However, talking to your healthcare provider before using Tufehart 500 mg Injection is essential. They will diagnose and confirm iron deficiency or anaemia, recommend the appropriate dosage and duration of treatment, and monitor your response to treatment, making adjustments as necessary. This ensures that you receive personalized care and optimal management of your iron levels.
To boost your iron levels, complement your iron supplement (Tufehart 500 mg Injection) with a balanced diet rich in iron-boosting foods. Opt for protein-rich options like red meat, poultry, and seafood, particularly shellfish and sardines. Legumes, including lentils, beans, and peas, are also packed with iron. Leafy greens like spinach, kale, collard greens, and broccoli are excellent choices. Pay attention to nuts and seeds like pumpkin seeds, sesame seeds, sunflower seeds, and whole grains like fortified cereals and quinoa. Dried fruits like apricots and prunes are also good sources of iron. Additionally, include a variety of cooked vegetables like bell peppers and sweet potatoes in your meals. Incorporating these iron-rich foods into your diet will support overall health and well-being.
You can take vitamin C/ Vitamin D/ multivitamin/ folic acid along with iron. In general, these vitamins do not cause any interactions, and they help in good iron absorption and healthy RBC. However, it's always a good idea to seek medical attention from a healthcare provider before starting any new supplement program to ensure it's appropriate for your specific health needs and to get proper guidance on usage.
Taking Tufehart 500 mg Injection with zinc may increase the risk of certain side effects. However, if it is essential to use together, your doctor may change the dose or how often you use one or both of the medicines.
There are no documented interactions between Tufehart 500 mg Injection and Tylenol (acetaminophen), but it is recommended that you inform your doctor before using them together to guarantee safety and prevent negative complications.
Taking Tufehart 500 mg Injection does not typically lead to weight gain. However, as your anaemia improves, you may experience weight fluctuations. If you notice any unexpected changes in your body weight during treatment, consult your doctor to discuss potential causes and appropriate guidance.
Causing constipation is the most common side effect of the Tufehart 500 mg Injection (especially in breastfeeding women if the doctor advises to use it). However, Tufehart 500 mg Injection is not typically linked to acne development. If you experience worsening constipation or unexpected acne, consult your healthcare provider for personalized advice and management.
The common side effects of Tufehart 500 mg Injection are nausea, flushing, dizziness, high blood pressure, Low levels of phosphorus in the blood, and some injection site reactions. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
Tufehart 500 mg Injection is generally considered safe when following the instructions recommended by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.5910 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. U.S. Food and Drug Administration (FDA). 203565S005Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Ferric Carboxymaltose Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. Ferric carboxymaltose. 2007. [Accessed on 23 Jan. 2019] Check here
  5. Ferric Carboxymaltose Ferric Carboxymaltose. 2013. [Accessed on 07 Apr. 2019] Check here
  6. Ferric carboxymaltose injection [Prescribing Inforamtion]. 2021. [Accessed on 25 Jul. 2024] Check here
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 07 Apr. 2019]Check here

Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,India
Other Info - TUF0081

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