Valance Oral Solution | Uses, Side Effects, Price

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Prescription Medicine

Valance Oral Solution is used to treat seizures and manage manic episodes in bipolar disorder. It also helps prevent migraine attacks. It supports better brain stability and reduces symptom frequency. This helps improve daily functioning and overall quality of life.

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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More about the Product

Composition :

VALPROIC ACID-500MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Valance Oral Solution

Valance Oral Solution is used to treat epilepsy/seizures/fits. In addition, Valance Oral Solution also treats manic episodes associated with bipolar disorder. Additionally, it can prevent migraine symptoms (such as headache).

Valance Oral Solution contains valproic acid, which helps stabilise abnormal brain activity. It supports effective seizure control and helps calm overactive neural activity. It also helps manage mood changes in bipolar disorder and reduces the frequency of migraine attacks. This improves neurological balance and supports better functioning.

Administer Valance Oral Solution with food to prevent gastrointestinal upset. You may sometimes experience nausea, upset stomach or stomach pain, tremors (shakes), sleepiness, headache, weight gain and thinning hair. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic to any components present in Valance Oral Solution . If you are pregnant, do not take Valance Oral Solution because it may cause serious congenital defects. Valance Oral Solution is generally not recommended during breastfeeding; consult your physician before taking Valance Oral Solution .

Uses of Valance Oral Solution

Valance Oral Solution is used for the treatment of epilepsy (seizures), bipolar disorder, and migraine. The detailed uses of Valance Oral Solution are as follows:

Controls Seizures: Valance Oral Solution helps prevent and control seizures by calming overactive neural activity.
Manages Bipolar Disorder: Valance Oral Solution helps to control manic episodes and stabilise mood in individuals with bipolar disorder.
Prevents Migraine Headaches: Valance Oral Solution is also prescribed as a preventive treatment to reduce the frequency and severity of migraine attacks.

Key Benefits

Valance Oral Solution , when used as prescribed, may provide the following benefits:

For Controls Seizures:

Helps stabilise abnormal electrical activity in the brain.
Reduces sudden episodes of excessive brain stimulation

For Managing Bipolar Disorder:

Helps maintain emotional balance.
Reduces the intensity and frequency of extreme mood changes

For Preventing Migraine Headaches:

Helps reduce the risk of recurrent severe headaches.
Reduces the impact of migraine on daily life.

Side effects of Valance Oral Solution 500 ml

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Back pain

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Increased Hunger

Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
Get quality sleep for about 7-9 hours.
Try to manage stress with meditation or yoga.
Drink enough water.
Exercise regularly as it helps regulate appetite.

Directions for Use

Valance Oral Solution can be taken with food to avoid stomach upset.
It is usually taken twice daily; however, your doctor may adjust the dosage and timing based on your medical condition and response to treatment.
Swallow Valance Oral Solution as a whole with a glass of water.
Do not crush or chew this medication.

How Valance Oral Solution Works

Valance Oral Solution contains valproic acid, which helps calm excessive nerve activity in the brain. As a result, it aids in controlling seizures. In bipolar disorder, Valance Oral Solution raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. In migraine, Valance Oral Solution limits the transmission of pain, thereby preventing migraine.

Alcohol

Unsafe

Do not consume alcohol while taking Valance Oral Solution as alcohol can worsen the side effects of the Valance Oral Solution , including sleepiness and dizziness.

Pregnancy

Unsafe

Valance Oral Solution is a Category D pregnancy drug. It is not recommended for use during pregnancy as it may cause an increase in the risk of a cleft lip, which is a congenital disability in the unborn baby. If you are a female able to have a baby, you must use an effective method of birth control (contraception) without interruption during your entire treatment with Valance Oral Solution .

Breast Feeding

Caution

Valance Oral Solution passes into breast milk and may harm your infant. Please consult a doctor if you are breastfeeding before taking Valance Oral Solution . Breastfed infants are at risk for valproic acid-induced hepatotoxicity, so infants should be monitored for jaundice and other signs of liver damage during maternal therapy.

Driving

Unsafe

Valance Oral Solution may cause dizziness, drowsiness, or fatigue in some individuals. Therefore, avoid driving if you feel drowsy, dizzy or tired after taking Valance Oral Solution .

Liver

Caution

Inform your doctor before taking the Valance Oral Solution if you have a history of liver diseases. Extreme caution is recommended in patients with impaired liver function. Your doctor will weigh the benefits and potential risks before prescribing Valance Oral Solution .

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please inform your doctor if you have kidney impairment.

Children

Caution

Use is not recommended for children under 10 years old. Your doctor will decide the dose based on your child's condition if they are more than ten years old.

Heart

Caution

Valance Oral Solution can be used cautiously in patients with heart disease if prescribed by a physician.

Geriatrics

Caution

Valance Oral Solution can be given to elderly patients with extreme caution if prescribed by a physician.

What if I have taken an overdose of Valance Oral Solution

Avoid exceeding the prescribed dose, as this may lead to adverse effects. Symptoms of adverse effects may include sleepiness, an irregular heartbeat, and coma (loss of consciousness). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

Diet:

Follow a high-fat, low-carbohydrate diet if advised by your doctor.
Maintain a balanced meal plan to support overall health.

Physical Activity:

Exercise regularly to help maintain a healthy weight and general fitness.

Safety & Preparedness:

Keep a seizure response plan and inform people around you.
Make simple home safety changes to reduce injury risk.
Identify and avoid known seizure triggers.
Use an alarm or emergency device to call for help during a seizure.

Rest & Sleep:

Get enough rest and sleep to reduce seizure risk.

Habits:

Avoid smoking and alcohol consumption.

Stress Management:

Practice meditation or yoga to reduce stress and improve coping ability.

Have a query?

How Soon It Starts Working

The time required for Valance Oral Solution to start to work: Valance Oral Solution ideally shows its action within 1 to 4 hours after administration.
The time for which the effects of Valance Oral Solution last: The effect of Valance Oral Solution lasts for 13 to 19 hours.

What if you forget to take Valance Oral Solution

If you forget to take a dose of Valance Oral Solution , take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dose. Do not take a double dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Valance Oral Solution out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Before taking the Valance Oral Solution , let your doctor know about all your medical conditions, sensitivities, and all medications you are using.
Inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby, or are breastfeeding.
You should not become pregnant during treatment with Valance Oral Solution .
Consult your doctor immediately if you become pregnant while taking Valance Oral Solution .
Alcohol should be avoided during treatment with this medicine.
You must not drive or operate machinery while taking Valance Oral Solution .

Drug-Drug Interactions

Drug-Drug Interactions: Inform your doctor if you are taking any of the following medicines, as there may be an interaction.

Immunity-lowering medicines (Leflunomide, Teriflunomide)
• Potential effect: May increase the risk of liver problems when used together.
Anaesthetic (loss of sensation) and pain-relief medicine (Ketamine)
• Potential effect: May increase side effects and cause respiratory depression.
Mood-stabilising medicine (Lithium)
• Potential effect: May increase the risk of irregular heart rhythm.
Strong pain-relief medicine – Opioid (Buprenorphine)
• Potential effect: May increase the risk of severe side effects, including breathing problems and loss of consciousness.
Antibiotic medicines (Ertapenem, Meropenem)
• Potential effect: May reduce the blood levels of Valance Oral Solution and decrease its effectiveness.

Drug-Food Interactions:

Alcohol: Avoid alcohol while taking Valance Oral Solution , as it may increase dizziness and sleepiness.

Drug-Disease Interactions: Inform your doctor if you have a history of this condition before taking Valance Oral Solution .

Depression
Liver disease
Urea cycle disorders (ammonia buildup disorders)
Suicidal thoughts
HIV disease
Hereditary mitochondrial disorders
Thrombocytopenia (low platelets)

DivalproexGlycerol phenylbutyrate

Critical

DivalproexErtapenem

Severe

Drug-Drug Interactions

DivalproexGlycerol phenylbutyrate

Critical

How does the drug interact with Valance Oral Solution 500 ml:
Coadministration of Glycerol phenylbutyrate and Valance Oral Solution 500 ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Valance Oral Solution 500 ml together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

DivalproexErtapenem

Severe

How does the drug interact with Valance Oral Solution 500 ml:
Coadministration of Ertapenem with Valance Oral Solution 500 ml may reduce the blood levels of Valance Oral Solution 500 ml and increase the risk of developing seizures.

How to manage the interaction:
Although there is a possible interaction, ertapenem can be taken with Valance Oral Solution 500 ml if prescribed by the doctor. Consult the doctor if you experience loss of seizure control or changes in behaviour. Do not stop using any medications without talking to your doctor.

DivalproexDoripenem

Severe

How does the drug interact with Valance Oral Solution 500 ml:
Co-administration of Valance Oral Solution 500 ml and Doripenem can reduce the blood levels of Valance Oral Solution 500 ml sodium and increase the risk of developing seizures.

How to manage the interaction:
Co-administration of Valance Oral Solution 500 ml with Doripenem can possibly result in an interaction, it can be taken when your doctor has advised it. Do not stop using any medications without first talking to your doctor.

DivalproexLamotrigine

Severe

How does the drug interact with Valance Oral Solution 500 ml:
Coadministration of Valance Oral Solution 500 ml and Lamotrigine can increase the risk and severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Valance Oral Solution 500 ml and Lamotrigine, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience restlessness, rash, or muscle weakness. Do not stop using any medications without a doctor's advice.

DivalproexLomitapide

Severe

How does the drug interact with Valance Oral Solution 500 ml:
Co-administration of Valance Oral Solution 500 ml and Lomitapide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Valance Oral Solution 500 ml and lomitapide can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like fever, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without the doctor's advice.

DivalproexMeropenem

Severe

How does the drug interact with Valance Oral Solution 500 ml:
Co-administration of Valance Oral Solution 500 ml and Meropenem can reduce the blood levels of Valance Oral Solution 500 ml sodium.

How to manage the interaction:
Co-administration of Valance Oral Solution 500 ml with Meropenem can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without a doctor's advice.

DivalproexMipomersen

Severe

How does the drug interact with Valance Oral Solution 500 ml:
Co-administration of Valance Oral Solution 500 ml and mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Valance Oral Solution 500 ml and mipomersen can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Avoid alcohol consumption, and Do not stop using any medications without a doctor's advice.

DivalproexLeflunomide

Severe

How does the drug interact with Valance Oral Solution 500 ml:
Co-administration of Valance Oral Solution 500 ml and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Valance Oral Solution 500 ml and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

DivalproexKetoconazole

Severe

How does the drug interact with Valance Oral Solution 500 ml:
Coadministration of Ketoconazole and Valance Oral Solution 500 ml may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Valance Oral Solution 500 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain, fatigue, nausea, vomiting, stomach pain, dark urine, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

DivalproexVorinostat

Severe

How does the drug interact with Valance Oral Solution 500 ml:
Coadministration of Valance Oral Solution 500 ml and Vorinostat can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Valance Oral Solution 500 ml and Vorinostat, you can take these medicines together if prescribed by your doctor. If you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Habit Forming

Therapeutic Class

[ANTICONVULSANT]

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Author Details

Written By

Santoshini Reddy G
M Pharmacy

Reviewed By

Dr Aneela Siddabathuni
MPharma., PhD

Last Updated

Feb 12, 2026 | 7:22 AM IST

We provide you with authentic, trustworthy and relevant information.

See our editorial policy

Reference

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot â€“ C, â€œGâ€ Block, Bandra-Kurla Complex, Bandra (East), Mumbai â€“ 400 051, India

Other Info - VAL0271

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Welcome User

Valance Oral Solution 500 ml

Delivery Information

More about the Product

Composition :

Manufacturer/Marketer :

Consume Type :

Expires on or after :

Return Policy :

About Valance Oral Solution

Uses of Valance Oral Solution

Key Benefits

Stomach Pain

Back pain

Constipation

Loose And Watery Stools

Dizziness

Nausea

Increased Hunger

Directions for Use

How Valance Oral Solution Works

Alcohol

Pregnancy

Breast Feeding

Driving

Liver

Kidney

Children

Heart

Geriatrics

What if I have taken an overdose of Valance Oral Solution

Diet & Lifestyle Advise

How Soon It Starts Working

What if you forget to take Valance Oral Solution

Storage

Drug Warnings

Drug-Drug Interactions

Drug-Drug Interactions

Drug-Food Interactions

Drug-Food Interactions

Habit Forming

Therapeutic Class

FAQs

What is the use of Valance Oral Solution ?

How does Valance Oral Solution help to control seizures?

Is Valance Oral Solution used to treat bipolar disorder?

Does Valance Oral Solution help in preventing migraine?

Does Valance Oral Solution cause weight gain?

I am planning for pregnancy. Is it safe to take Valance Oral Solution ?

Does prolonged intake of Valance Oral Solution causes weight gain?

What are the side effects of Valance Oral Solution ?

What does Valance Oral Solution contain?

When should I take Valance Oral Solution ?

Can I consume alcohol while taking Valance Oral Solution ?

Does Valance Oral Solution cause an addiction?

For how long should I take Valance Oral Solution to cure my epilepsy completely?

What happens if I stop taking Valance Oral Solution ?

Does Valance Oral Solution affect the working of birth control pills?

Is it safe to take Valance Oral Solution for long term?

I am concerned because I have heard that Valance Oral Solution causes hair loss. Is it true?

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