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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Valance Oral Solution is used to treat seizures. Besides this, it is also used to treat manic episodes associated with bipolar disorder and prevent migraine symptoms. It contains Valproic acid which works by reducing abnormal electrical activity in the brain. It also produces a calming effect and limits the transmission of pain signals. This medicine may sometimes cause side effects such as nausea, upset stomach, tremors, sleepiness, headache, and weight gain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

VALPROIC ACID-500MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About Valance Oral Solution

Valance Oral Solution belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. In addition, Valance Oral Solution also treats manic episodes associated with bipolar disorder. Besides this, it can also prevent migraine symptoms (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state.

Valance Oral Solution contains Valproic acid, which reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Valance Oral Solution raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Valance Oral Solution limits the transmission of nerve pain, thereby preventing migraine headaches.

Valance Oral Solution should be taken as prescribed by the doctor. You may sometimes experience nausea, upset stomach or stomach pain, tremors (shakes), sleepiness, headache, weight gain and thinning hair. Most of these side effects are temporary and will go away on their own. However, if you suffer these adverse effects on a regular basis, you should consult your doctor.

Inform your doctor if you are allergic to any components present in Valance Oral Solution . If you are pregnant, do not take Valance Oral Solution because it may cause serious congenital defects. Use effective contraception if you are of childbearing age while taking Valance Oral Solution . If you are breastfeeding, inform your doctor before taking Valance Oral Solution . As Valance Oral Solution causes sleepiness and dizziness, do not drive or operate machinery. Avoid drinking alcohol with Valance Oral Solution as it may cause dizziness and tiredness. To rule out any negative effects, keep your doctor updated about your health condition and medications.

Uses of Valance Oral Solution

Valance Oral Solution is used for the treatment of epilepsy (seizures), bipolar disorder, and migraine. The detailed uses of Valance Oral Solution are as follows:

  • Controls Seizures: Valance Oral Solution helps to prevent and control seizures by calming overactive brain signals.
  • Manages Bipolar Disorder: Valance Oral Solution helps to control manic episodes and stabilize mood in individuals with bipolar disorder.
  • Prevents Migraine Headaches: Valance Oral Solution is also prescribed as a preventive treatment to reduce the frequency and severity of migraine attacks.

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Directions for Use

  • Valance Oral Solution can be taken with food to avoid stomach upset.
  • It is usually taken twice daily; however, your doctor may adjust the dosage and timing based on your medical condition and response to treatment.
  • Swallow Valance Oral Solution as a whole with a glass of water.
  • Do not crush or chew this medication.

Key Benefits

Valance Oral Solution contains Valproic acid, an anticonvulsant (or anti-epileptic) medicine that reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Valance Oral Solution raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Valance Oral Solution limits the transmission of nerve pain, thereby preventing migraine headaches.

How Valance Oral Solution Works

Valance Oral Solution contains Valproic acid, which reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Valance Oral Solution raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Valance Oral Solution limits the transmission of nerve pain, thereby preventing migraine headaches.

Storage

Store in a cool and dry place away from sunlight
Side effects of Valance Oral Solution 500 ml
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.

What if I have taken an overdose of Valance Oral Solution

Take Valance Oral Solution only as prescribed by the doctor. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include sleepiness, irregular heartbeat, and coma (loss of consciousness for a period of time). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Before taking the Valance Oral Solution , let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby, or are breastfeeding. You should not become pregnant while you are receiving Valance Oral Solution . Consult your doctor immediately if you become pregnant while receiving a Valance Oral Solution . Alcohol should be avoided during treatment with this medicine. You must not drive or operate machinery while receiving Valance Oral Solution .

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Valance Oral Solution 500 ml:
Coadministration of Glycerol phenylbutyrate and Valance Oral Solution 500 ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Valance Oral Solution 500 ml together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Valance Oral Solution 500 ml:
Co-administration of Valance Oral Solution 500 ml and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Valance Oral Solution 500 ml and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DivalproexSodium oxybate
Severe
How does the drug interact with Valance Oral Solution 500 ml:
Co-administration of Sodium oxybate and Valance Oral Solution 500 ml can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Sodium oxybate and Valance Oral Solution 500 ml can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like dizziness, sweating, palpitations, and shortness of breath, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Valance Oral Solution 500 ml:
Coadministration of Ketoconazole and Valance Oral Solution 500 ml may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Valance Oral Solution 500 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain, fatigue, nausea, vomiting, stomach pain, dark urine, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexEsketamine
Severe
How does the drug interact with Valance Oral Solution 500 ml:
Coadministration of Esketamine and Valance Oral Solution 500 ml can increase the side effects of esketamine.

How to manage the interaction:
Although taking Valance Oral Solution 500 ml and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any symptoms like drowsiness and impaired motor coordination, consult the doctor immediately. Do not stop using any medications without talking to your doctor.
DivalproexSodium phenylbutyrate
Severe
How does the drug interact with Valance Oral Solution 500 ml:
Co-administration of Sodium phenylbutyrate and Valance Oral Solution 500 ml can increase ammonia levels in the blood and is generally not recommended for patients with urea cycle disorders.

How to manage the interaction:
Co-administration of Valance Oral Solution 500 ml with Sodium phenylbutyrate can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Valance Oral Solution 500 ml:
Coadministration of Valance Oral Solution 500 ml and Lamotrigine can increase the risk and severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Valance Oral Solution 500 ml and Lamotrigine, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience restlessness, rash, or muscle weakness. Do not stop using any medications without a doctor's advice.
How does the drug interact with Valance Oral Solution 500 ml:
Co-administration of Valance Oral Solution 500 ml and teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Valance Oral Solution 500 ml and teriflunomide can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Valance Oral Solution 500 ml:
Co-administration of Valance Oral Solution 500 ml and Doripenem can reduce the blood levels of Valance Oral Solution 500 ml sodium and increase the risk of developing seizures.

How to manage the interaction:
Co-administration of Valance Oral Solution 500 ml with Doripenem can possibly result in an interaction, it can be taken when your doctor has advised it. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Valance Oral Solution 500 ml:
Co-administration of Valance Oral Solution 500 ml and Ketamine can increase the risk of side effects.

How to manage the interaction:
Co-administration of Valance Oral Solution 500 ml and Ketamine can lead to an interaction, it can be taken if advised by your doctor. If you have any symptoms such as dizziness, drowsiness, shortness of breath, or impairment in thinking and motor coordination, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Adolescents and adults are advised to follow the Atkins diet (high fat, low carbohydrate).
  • Exercising on a regular basis aids with weight maintenance and general health.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and drinking alcohol.
  • Meditation and yoga can help reduce stress, reduce pain sensitivity, and increase coping abilities.
  • Have a seizure response plan in place, and make sure everyone around you knows what to do in the event of a seizure.
  • Prepare your living environment; simple changes may help reduce the risk of physical damage during a seizure.
  • Understand what causes seizures and try to reduce or avoid them.
  • Please keep your overall health in mind, as it can aid in the reduction of seizure activity.
  • Install an alarm or an emergency gadget to summon help during a seizure attack.

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

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Alcohol

Safe if prescribed

Do not consume alcohol while taking Valance Oral Solution as alcohol can worsen the side effects of the Valance Oral Solution , including sleepiness and dizziness.

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Pregnancy

Consult your doctor

Valance Oral Solution is a Category D pregnancy drug. It is not recommended for use during pregnancy as it may cause an increase in the risk of a cleft lip, which is a congenital disability in the unborn baby. If you are a female able to have a baby, you must use an effective method of birth control (contraception) without interruption during your entire treatment with Valance Oral Solution .

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Breast Feeding

Consult your doctor

Valance Oral Solution passes into breast milk and may harm your infant. Please consult a doctor if you are breastfeeding before taking Valance Oral Solution . Breastfed infants are at risk for valproic acid-induced hepatotoxicity, so infants should be monitored for jaundice and other signs of liver damage during maternal therapy.

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Driving

Safe if prescribed

Valance Oral Solution may cause dizziness, drowsiness or tiredness in some people. Therefore, avoid driving if you feel drowsy, dizzy or tired after taking Valance Oral Solution .

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Liver

Consult your doctor

Inform your doctor before receiving the Valance Oral Solution if you have a history of liver diseases/conditions. Extreme caution is recommended in patients with impaired liver function. Your doctor will weigh the benefits and potential risks before prescribing Valance Oral Solution .

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please inform your doctor if you have kidney impairment.

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Children

Safe if prescribed

Use is not recommended for children less than ten years. Your doctor will decide the dose based on your child's condition if more than ten years.

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Heart

Valance Oral Solution can be used in heart patients if prescribed by the physician.

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Geriatrics

Consult your doctor

Valance Oral Solution can be given in elderly patients with extreme caution, if prescribed by the physician.

FAQs

Valance Oral Solution is used to treat epilepsy/seizures/fits. In addition, it also helps treat manic episodes associated with bipolar disorder and prevent migraine symptoms (like a headache).

Valance Oral Solution decreases the excessive and abnormal nerve activity in the brain. Thereby helping in controlling seizures.

Valance Oral Solution helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect.

Valance Oral Solution limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition which is characterized by intense headaches.

Valance Oral Solution may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with Valance Oral Solution . Avoid getting pregnant while taking Valance Oral Solution as it could lead to serious birth defects. Do not stop taking Valance Oral Solution and consult your doctor immediately if you become pregnant.

Valance Oral Solution may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Valance Oral Solution may cause common side effects such as nausea, vomiting, headache, sleepiness, tremor, weakness, dizziness, stomach pain, and weight gain. If these side effects persist or worsen, please consult your doctor.

Valance Oral Solution contains Valproic acid as its active ingredient.

Take Valance Oral Solution with or without food as advised by your doctor.

You are recommended to avoid alcohol consumption while taking Valance Oral Solution as it may worsen the side effects of the Valance Oral Solution , including sleepiness and dizziness.

No, Valance Oral Solution does not cause addiction. However, Valance Oral Solution should be used as per dose and duration prescribed by your doctor. Do not self-medicate.

Valance Oral Solution does not cure epilepsy, it only helps to prevent the seizures. However, you have to take Valance Oral Solution for as long as it is advised by your doctor. If you face any difficulty while taking Valance Oral Solution , consult your doctor.

If you stop taking Valance Oral Solution suddenly, it may increase the risk of recurrence of seizures. Therefore, it should be stopped gradually. If you feel the need to stop taking Valance Oral Solution , please consult your doctor.

Some birth control pills (oestrogen-containing birth control pills) may lower the levels of Valance Oral Solution in blood. Thus, inform your doctor if you are using birth control pills and discuss with your doctor about the suitable method of contraception.

Valance Oral Solution is safe to take for long time in many patients if prescribed by a doctor. In rare cases, prolonged use of Valance Oral Solution may weaken your bones, thereby increasing their risk of breaking easily (osteopenia and osteoporosis). Get regular checkups done for bone health if you are taking Valance Oral Solution for a long time.

Valance Oral Solution may cause hair thinning, hair colour changes and even hair loss. If you have any concerns regarding this, please ask your doctor if it is possible to lower the dose of Valance Oral Solution . Your hair may regrow after either lowering your dose or changing medication.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - VAL0271

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