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compositionComposition:DOXYCYCLINE-100MG
prescription
Prescription Medicine
info
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Venucyclin 100 mg Injection 10 ml is an antibiotic medicine used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections, and periodontitis. This medicine contains doxycycline which works by inhibiting the protein synthesis of the bacterial cell and thereby helps fight infection-causing bacteria. This medicine is not effective for treating viral infections. Common side effects include pain, itching, swelling or redness at the site of injection, nausea, vomiting, or diarrhoea.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

DOXYCYCLINE-100MG

Manufacturer/Marketer :

Venus Remedies Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Venucyclin 100 mg Injection 10 ml

Venucyclin 100 mg Injection 10 ml is a sterile injection used to treat a wide variety of severe bacterial infections. This medicine belongs to a class of antibiotics that stop the growth of bacteria, helping your body fight off the infection. It is typically prescribed when oral medications are not suitable or when a rapid clinical response is required.

Because this medicine is injected directly into a vein, it is usually given at regular intervals to maintain a consistent level in your body. Your healthcare provider will schedule these injections as prescribed, and it is vital to complete the entire course of treatment even if you feel better. To support your recovery, stay well-hydrated, eat a balanced diet, and get plenty of rest while receiving this therapy.

While receiving Venucyclin 100 mg Injection 10 ml, you may experience mild side effects like nausea, vomiting, or irritation at the injection site. However, if you notice severe symptoms such as a severe skin rash, yellowing of your eyes or skin, or persistent watery diarrhoea, you should contact your doctor immediately. These serious reactions require prompt medical attention.

Before starting treatment, tell your doctor if you have liver disease, kidney problems, or a history of allergic reactions to similar antibiotics. Do not take this medicine if you are pregnant or breastfeeding, as it can affect developing teeth and bones. It should also be avoided in young children unless specifically directed by a doctor.

Venucyclin 100 mg Injection 10 ml can interact with blood thinners such as warfarin and may increase their effect, which can raise the risk of bleeding. Your doctor may monitor you more closely if you are taking these medicines together. It is important to discuss your alcohol use with your doctor. Although alcohol is not known to significantly affect intravenous Venucyclin 100 mg Injection 10 ml directly, heavy alcohol consumption may slow your recovery and increase the risk of side effects. Your doctor can advise you on what is safest during treatment.

Uses of Venucyclin 100 mg Injection 10 ml

Your doctor may prescribe Venucyclin 100 mg Injection 10 ml to help manage the following conditions:

  • Severe bacterial pneumonia: Venucyclin 100 mg Injection 10 ml helps by stopping the growth of the bacteria causing the lung infection, allowing your lungs to clear.
  • Rickettsial infections (such as tick fevers): It targets and eliminates the specific bacteria transmitted by ticks, lice, or mites.
  • Severe urinary tract infections: It clears the bacterial overgrowth in the urinary system to relieve pain and frequent urination.
  • Skin and soft tissue infections: It halts the spread of bacteria in deep skin layers, reducing swelling, redness, and pain.
  • Intra-abdominal infections: When combined with other treatments, it helps resolve complex bacterial infections inside the abdomen.

Key Benefits

When used as directed as part of your treatment plan, this medicine may provide the following benefits:

  • Fast-Acting Infection Control: Because Venucyclin 100 mg Injection 10 ml is injected directly into your bloodstream, it begins working almost immediately to fight off harmful bacteria, leading to a faster recovery from severe infections.
  • Alternative When Oral Medicines Aren't Possible: If you are unable to take oral medications due to severe illness, nausea, or surgery, this injection ensures you still receive the vital antibiotic treatment you need without relying on your digestive tract.
  • Broad-Spectrum Bacterial Coverage: This medicine is effective against many different types of bacteria when they are susceptible to Venucyclin 100 mg Injection 10 ml. Your doctor may use culture or sensitivity test results, when available, to help choose the most appropriate antibiotic for your infection. 
Side effects of Venucyclin 100 mg Injection 10 ml
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Venucyclin 100 mg Injection 10 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Venucyclin 100 mg Injection 10 ml Works

Venucyclin 100 mg Injection 10 ml contains doxycycline and works by entering the bacterial cells and blocking their ability to produce essential proteins. Bacteria require these proteins to grow, multiply, and survive. By stopping protein production, the medicine prevents the bacteria from spreading further. This allows your body's natural immune system to easily target and destroy the remaining bacteria, clearing the infection.
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Alcohol

Caution

It is not known if alcohol affects Venucyclin 100 mg Injection 10 ml. Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Venucyclin 100 mg Injection 10 ml belongs to pregnancy category D. There are no adequate and well-controlled studies on the use of Venucyclin 100 mg Injection 10 ml in pregnant women. In some cases, taking Venucyclin 100 mg Injection 10 ml during pregnancy may affect tooth and bone development in the unborn baby. So, if you are pregnant or planning for pregnancy contact the doctor before using Venucyclin 100 mg Injection 10 ml.

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Breast Feeding

Caution

Venucyclin 100 mg Injection 10 ml is excreted in the breast milk. However, the extent of absorption of Venucyclin 100 mg Injection 10 ml by the breastfed infant is not known. Hence, the nursing mother should consult the doctor before using Venucyclin 100 mg Injection 10 ml.

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Driving

Caution

It is not known if Venucyclin 100 mg Injection 10 ml affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Caution

Venucyclin 100 mg Injection 10 ml is to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Safe if prescribed

At the recommended doses, Venucyclin 100 mg Injection 10 ml is safe to use in patients with kidney disease if prescribed by a doctor.

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Children

Caution

Use of Venucyclin 100 mg Injection 10 ml during tooth development in infants and children below 8 years of age may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for children below 8 years of age.

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Heart

Consult your doctor

Consult your doctor if you have a history of heart disease. Your doctor will weigh the benefits and risks before administering Venucyclin 100 mg Injection 10 ml.

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Geriatrics

Consult your doctor

Please consult a doctor before receiving Venucyclin 100 mg Injection 10 ml in geriatric patients, as they may be more sensitive to side effects.

What if I have taken an overdose of Venucyclin 100 mg Injection 10 ml

Since this medication is given by trained medical professionals, an overdose is highly unlikely. If you suspect you have received too much or experience severe symptoms after an infusion, notify your healthcare team or seek immediate medical attention right away.

Diet & Lifestyle Advise

  • Protect your skin from the sun: This medicine can make your skin highly sensitive to sunlight. Wear protective clothing and apply a high-SPF sunscreen when outdoors, and avoid tanning beds.
  • Stay well-hydrated: Drink plenty of fluids (unless advised otherwise by your doctor) to help your body process the medication and support recovery.
  • Support your gut health: Consider eating yoghurt or taking a probiotic supplement after completing your antibiotic course to help restore the healthy bacteria in your gut. Talk to your doctor or pharmacist first.
  • Inform your healthcare team about other IV fluids: If you are receiving calcium-containing solutions intravenously, tell your healthcare provider, as they should not be mixed in the same IV line as Venucyclin 100 mg Injection 10 ml.
health query

Have a query?

How Soon It Starts Working

The time required for Venucyclin 100 mg Injection 10 ml to start to work: The exact onset time of Venucyclin 100 mg Injection 10 ml has not been clinically established. The time for which the effects of Venucyclin 100 mg Injection 10 ml last: The duration of Venucyclin 100 mg Injection 10 ml’s effect is clinically not established.

What if you forget to take Venucyclin 100 mg Injection 10 ml

Because you will receive this medicine from a healthcare provider, it is unlikely that you will miss a dose. However, if you miss an appointment for your injection, contact your healthcare provider immediately to reschedule.

Storage

•Prior to mixing, store the dry powder vials at room temperature, ideally between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the solution: Before giving the medicine, ensure the healthcare professional inspects the liquid. It should be clear and free of particles or discolouration.
  • Monitor the injection site: Pay close attention to the area around your IV line. If you experience burning, redness, or swelling, alert your healthcare provider immediately to prevent tissue irritation.
  • Complete the full course: Even if your symptoms disappear after a few doses, finish the entire prescribed treatment to ensure the infection is completely cleared and to prevent bacterial resistance.
  • Check for pregnancy: This medicine is generally not recommended during pregnancy because it may affect the developing baby's teeth and bones. If you are pregnant or think you may be pregnant, tell your doctor before starting treatment.
  • Do not share equipment: If you are receiving this treatment at home under professional supervision, ensure all needles and IV supplies are sterile and disposed of in a proper sharps container.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (like warfarin): Venucyclin 100 mg Injection 10 ml may increase the effect of these medications, raising your risk of bleeding.
  • Seizure medications (like phenobarbital, phenytoin, or carbamazepine): These drugs can speed up how quickly your body processes Venucyclin 100 mg Injection 10 ml, making it less effective.
  • Retinoid medicines (like isotretinoin): Combining these can increase pressure inside the skull, leading to severe headaches or vision issues.
  • Certain antibiotics (such as penicillins): In some situations, taking Venucyclin 100 mg Injection 10 ml together with certain antibiotics may affect how well one or both medicines work. Your doctor will prescribe this combination only when it is appropriate for your infection.
DoxycyclineAcitretin
Critical
DoxycyclineIsotretinoin
Critical

Drug-Drug Interactions

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DoxycyclineAcitretin
Critical
How does the drug interact with Venucyclin 100 mg Injection 10 ml:
Coadministration of Acitretin with Venucyclin 100 mg Injection 10 ml can increase the risk and severity of vision problems.

How to manage the interaction:
Taking Acitretin with Venucyclin 100 mg Injection 10 ml together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DoxycyclineIsotretinoin
Critical
How does the drug interact with Venucyclin 100 mg Injection 10 ml:
Taking isotretinoin with Venucyclin 100 mg Injection 10 ml may increase the risk of a rare condition called pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking isotretinoin and Venucyclin 100 mg Injection 10 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting doctor.
DoxycyclineTretinoin
Critical
How does the drug interact with Venucyclin 100 mg Injection 10 ml:
Coadministration of Tretinoin with Venucyclin 100 mg Injection 10 ml can increase the risk of side effects like vision problems.

How to manage the interaction:
Taking Tretinoin with Venucyclin 100 mg Injection 10 ml is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headache, nausea, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DoxycyclineEtretinate
Critical
How does the drug interact with Venucyclin 100 mg Injection 10 ml:
Taking Venucyclin 100 mg Injection 10 ml with etretinate may increase the risk of vision problems.

How to manage the interaction:
Taking Etretinate with Venucyclin 100 mg Injection 10 ml is not recommended, but can be taken if prescribed by a doctor. However, consult a doctor if you experience headache, nausea, vomiting, and visual disturbances. Do not discontinue any medication without consulting a doctor.
DoxycyclineAmoxicillin
Severe
How does the drug interact with Venucyclin 100 mg Injection 10 ml:
Co-administration of amoxicillin with Venucyclin 100 mg Injection 10 ml may reduce the therapeutic effect of amoxicillin.

How to manage the interaction:
Although there is a possible interaction between Amoxicillin and Venucyclin 100 mg Injection 10 ml, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
DoxycyclineAtracurium
Severe
How does the drug interact with Venucyclin 100 mg Injection 10 ml:
Co-administration of atracurium with Venucyclin 100 mg Injection 10 ml may increase the risk of breathing problems.

How to manage the interaction:
Although there is an interaction between Atracurium and Venucyclin 100 mg Injection 10 ml, bit it can be taken together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
DoxycyclineLomitapide
Severe
How does the drug interact with Venucyclin 100 mg Injection 10 ml:
Coadministration of lomitapide with Venucyclin 100 mg Injection 10 ml can increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Venucyclin 100 mg Injection 10 ml and Lomitapide, but it can be taken if prescribed by a doctor. However, contact your doctor if you experience fever, chills, joint pain, swelling, skin rash, itching, feeling tired, feeling sick, stomach ache, and dark urine. Do not stop using any medications without first talking to your doctor.
DoxycyclineKetoconazole
Severe
How does the drug interact with Venucyclin 100 mg Injection 10 ml:
Coadministration of Ketoconazole and Venucyclin 100 mg Injection 10 ml may increase the risk of liver problems.

How to manage the interaction:
Although taking Venucyclin 100 mg Injection 10 ml with Ketoconazole can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any symptoms such as joint pain or swelling, skin rash, itching, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue using any medications without consulting a doctor.
DoxycyclineFerrous fumarate
Severe
How does the drug interact with Venucyclin 100 mg Injection 10 ml:
Taking Venucyclin 100 mg Injection 10 ml with ferrous fumarate can reduce the levels and effects of Venucyclin 100 mg Injection 10 ml.

How to manage the interaction:
Although taking ferrous fumarate and Venucyclin 100 mg Injection 10 ml possibly results in an interaction, they can be taken together as advised by your doctor. However, consult a doctor if you experience any unusual symptoms. Do not stop using any medications without consulting a doctor.
DoxycyclineMipomersen
Severe
How does the drug interact with Venucyclin 100 mg Injection 10 ml:
Taking Venucyclin 100 mg Injection 10 ml with mipomersen may increase the risk of liver problems.

How to manage the interaction:
Although taking Venucyclin 100 mg Injection 10 ml with Mipomersen can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any symptoms such as joint pain or swelling, skin rash, itching, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue using any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Venucyclin 100 mg Injection 10 ml when used as directed. 
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Venucyclin 100 mg Injection 10 ml belongs to a group of medications called tetracycline antibiotics used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections (gonorrhoea, syphilis), and gum infections (periodontitis). Besides this, Venucyclin 100 mg Injection 10 ml may also be used to treat or prevent anthrax.
Venucyclin 100 mg Injection 10 ml stops the growth of bacteria by preventing the synthesis of essential proteins necessary for their survival. Thereby, Venucyclin 100 mg Injection 10 ml helps treat bacterial infections.
No, Venucyclin 100 mg Injection 10 ml should not be stopped even if you feel better as it is an antibiotic medication and completing the full course is necessary; otherwise, the infection might re-appear in a more severe form and will also become difficult to treat due to antibiotic resistance.
If you are taking Venucyclin 100 mg Injection 10 ml, avoid taking antacids containing aluminium, calcium or magnesium or other drugs containing these cations; oral zinc, iron salts or bismuth preparations within 2 hours of consumption of Venucyclin 100 mg Injection 10 ml as they may affect the absorption of Venucyclin 100 mg Injection 10 ml. Avoid taking dairy products within 2 hours of taking Venucyclin 100 mg Injection 10 ml as they may also impair the absorption of Venucyclin 100 mg Injection 10 ml.
Use of Venucyclin 100 mg Injection 10 ml during tooth development (last half of pregnancy, infancy, and in children below the age of 8 years) may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for pregnant women, breastfeeding mothers, and children below 8 years of age.
Venucyclin 100 mg Injection 10 ml may make your skin sensitive to sunlight. So, apply sunscreen while going out and wear protective clothing and sunglasses. Avoid prolonged and unnecessary exposure to sunlight.
Venucyclin 100 mg Injection 10 ml may lower the effectiveness of hormonal contraceptives such as birth control pills, rings, patches, or injections. Consult your doctor if you have any concerns, your doctor may advise regarding other forms of contraception.
Venucyclin 100 mg Injection 10 ml does not completely prevent malaria caused by P. falciparum as Venucyclin 100 mg Injection 10 ml is given as a prophylactic regimen (protection) whenever anyone enters a malaria-prone area.
Venucyclin 100 mg Injection 10 ml is given parenterally, which means it is injected directly into a vein as an intravenous (IV) infusion. This is done slowly by a trained healthcare professional, usually in a hospital or clinic. Talk to your doctor or pharmacist for more details.
Venucyclin 100 mg Injection 10 ml is generally not recommended for children younger than 8 years because exposure during tooth development may affect tooth colour. However, in certain serious infections, your doctor may decide that the benefits outweigh the risks. Always use this medicine exactly as prescribed by your child's doctor.
Most people can drive safely after receiving Venucyclin 100 mg Injection 10 ml, as it does not typically cause drowsiness. However, if you experience dizziness or vision changes as a side effect, you should avoid driving or operating machinery. Talk to your doctor or pharmacist if you feel unwell.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.4063 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. MedlinePlus. A601141 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Doxycycline Injection Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Doxycycline 100 mg Capsules – Summary of Product Characteristics [Internet]. London: electronic Medicines Compendium (emc); [Accessed on 2025 Sep 16]Check here
  5. Doxycycline Hyclate (Oral Route): Drug Information [Internet]. WebMD LLC; [Accessed on 2025 Sep 16]Check here
  6. Mu Q, Tavella VJ, Luo XM. Role of Lactobacillus reuteri in Human Health and Diseases. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. April 2018. [Accessed on 11th August 2022]Check here
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 28 Mar. 2019]Check here

Country of origin

India

Manufacturer/Marketer address

Sco 857, Cabin No. 10, 2nd Floor, Nac, Manimajra, Chandigarh (U.T.), 160101, India
Other Info - VEN0710
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