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Viropil Tablet is used to treat HIV-1 infection. It works by increasing the immune cells that help fight infections in the body and interfering with the working of certain enzymes which are necessary for the reproduction of the virus; thereby decreasing the amount of HIV in the blood. In some cases, this medicine may cause side effects such as fatigue, diarrhoea, headache, pain, fever, cough, and insomnia. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions. Practise safe sex and other necessary precautions as this medicine does not prevent the spread of HIV infection.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Viropil Tablet

Viropil Tablet is a prescription medication used to treat Human Immunodeficiency Virus type 1 (HIV-1) infection. It helps control the virus in your body, allowing your immune system to stay stronger and fight off other infections. This medication is typically prescribed for adults and children who meet specific weight requirements.

To get the best results, you must take Viropil Tablet consistently every day, exactly as your doctor prescribes. It can be taken with or without food, but taking it at the same time each day helps maintain a steady level of the medicine in your body. Combining this treatment with a balanced diet, regular exercise, and adequate rest can further support your overall immune health.

Some people may experience mild side effects, such as trouble sleeping, headaches, or tiredness, when starting Viropil Tablet . However, you must seek immediate medical attention if you notice signs of serious issues, such as a severe skin rash, yellowing of your skin or eyes, or signs of kidney problems like changes in urination.

Before starting Viropil Tablet , talk to your doctor if you have a history of liver problems (especially Hepatitis B or C), kidney disease, or bone issues. Do not take this if you are currently taking certain medications like dofetilide, as this can lead to serious, life-threatening drug interactions.

Certain medicines, including antacids containing calcium or magnesium, can stop your body from absorbing Viropil Tablet properly, so they should be taken at different times. Limit alcohol use because it can increase your risk of liver damage and worsen side effects. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor to discuss the risks and benefits before starting this treatment.

Uses of Viropil Tablet

Your doctor may prescribe Viropil Tablet to help manage the following conditions:

  • HIV-1 Infection: Viropil Tablet helps lower the amount of HIV in your body (viral load) and increases the number of CD4 cells, which are white blood cells that help fight off infections. This helps keep your immune system healthy and reduces the risk of HIV-related illnesses.
  • Post-Exposure Prophylaxis (PEP): In certain cases, under strict medical guidance, this medication may be used as part of a regimen to help prevent HIV infection after a potential exposure to the virus.

Key Benefits

Viropil Tablet offers significant health advantages for individuals managing HIV, helping them maintain their physical well-being and lead active lives.

  • Simplified Daily Routine: Because Viropil Tablet combines three different active medications into a single daily tablet, it reduces the number of pills you need to take. This makes it much easier to stay consistent with your treatment plan.
  • Robust Immune Support: By successfully keeping the virus at undetectable levels, this medicine prevents damage to your immune system, reducing your chances of falling ill from common or rare infections.
  • Lowered Risk of Transmission: When taken consistently and viral load becomes undetectable, this treatment significantly lowers the risk of passing the virus to others through sexual contact.
Side effects of Viropil Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

  • Viropil Tablet can be taken with or without food.
  • It is recommended to take Viropil Tablet once daily, or as advised by your doctor.
  • Swallow Viropil Tablet as a whole with a glass of water.
  • Do not break, chew, or crush it.

How Viropil Tablet Works

Viropil Tablet contains dolutegravir, lamivudine, and tenofovir disoproxil fumarate. It is a combination medication containing three distinct active ingredients that work together to stop HIV from multiplying in your body. Each component attacks the virus at a different stage of its lifecycle. The first active component, dolutegravir, is an integrase inhibitor. It works by blocking a viral enzyme called integrase. Without this enzyme, the virus cannot insert its genetic material into your healthy immune cells, stopping it from replicating. The second and third components, lamivudine and tenofovir disoproxil fumarate, belong to a class of medicines called reverse transcriptase inhibitors. These two ingredients mimic the natural building blocks that the virus uses to copy itself. When the virus tries to use these dummy blocks, the copying process is cut short, preventing the virus from spreading and infecting new cells. By combining these three actions, Viropil Tablet rapidly reduces the amount of virus in your blood to very low or undetectable levels, while allowing your body's immune cells to recover and grow stronger.
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Alcohol

Caution

It is not known whether Viropil Tablet interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Viropil Tablet might cause embryo-fetal toxicity when taken at the time of conception and during early pregnancy. Please consult your doctor if you have any concerns regarding this.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Viropil Tablet . Consult your doctor if you have any concerns regarding this.

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Driving

Caution

Viropil Tablet may cause dizziness. So, drive or operating machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Viropil Tablet is not recommended for children weighing below 35kgs. Consult your doctor if you have any concerns.

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Heart

Caution

Viropil Tablet should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using Viropil Tablet .

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Geriatrics

Caution

Viropil Tablet should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Viropil Tablet .

What if I have taken an overdose of Viropil Tablet

If you take more than your prescribed dose of Viropil Tablet , seek immediate emergency medical care or contact a poison control centre. Symptoms of an overdose may include severe dizziness, extreme nausea, or vomiting. Bring your medication bottle with you so healthcare providers know exactly what you have taken.

Diet & Lifestyle Advise

  • Stay Well-Hydrated: Drink plenty of fluids throughout the day to support kidney function, unless your doctor has advised you to limit your fluid intake.
  • Support Bone Health: Include calcium- and vitamin D-rich foods, such as dairy products, leafy green vegetables, or fortified foods, to help maintain healthy bones.
  • Eat a Balanced Diet: Choose meals rich in lean proteins, whole grains, healthy fats, fruits, and vegetables to support your immune system and overall health.
  • Practise Food Safety: Avoid raw or undercooked meat, seafood, eggs, and unpasteurised dairy products to reduce the risk of foodborne infections.
  • Stay Physically Active: Engage in regular weight-bearing and muscle-strengthening exercises, such as walking or resistance training, to help maintain bone strength, muscle mass, and cardiovascular health.
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How Soon It Starts Working

The time required for Viropil Tablet to start to work: Viropil Tablet shows its action within 2 to 4 hours of administration. The time for which the effects of Viropil Tablet last: Viropil Tablet effect lasts for 24 hours.

What if you forget to take Viropil Tablet

If you miss a dose of Viropil Tablet , take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a forgotten one. Keeping a consistent daily routine is vital to prevent the virus from becoming resistant to the medication.

Storage

• Store Viropil Tablet tablets in their original container at room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Do not share your medicine: This medication is prescribed for your specific condition; sharing it can lead to severe health complications for others and will not prevent HIV transmission if taken incorrectly.
  • Inspect the packaging: Always check the safety seal on your bottle before opening. If the bottle is damaged, damp, or the tablets appear discoloured or crumbly, return it to your pharmacy for a replacement.
  • Get your kidney and liver function checked: Ensure you attend all scheduled appointments for blood tests, as your doctor needs to monitor your kidneys, liver, and CD4 counts regularly while you take this medicine.
  • Beware of Hepatitis B flare-ups: If you have both HIV and Hepatitis B, stopping Viropil Tablet suddenly can cause a severe, life-threatening flare-up of your Hepatitis B. Never stop this medicine without your doctor's explicit guidance.
  • Check your bone health: If you have a history of bone loss or osteoporosis, ask your doctor if you need a bone density scan, as this medication can affect your bone strength over time.

Drug-Drug Interactions

verifiedApollotooltip

Viropil Tablet may interact with certain medicines, affecting its effectiveness or increasing the risk of side effects.

  • Antacids and Mineral Supplements: Supplements containing calcium, iron, zinc, magnesium, or aluminium can bind with this medicine and severely lower its absorption. Take these supplements at least 2 hours before or 6 hours after your dose.
  • Dofetilide: Taking this heart medication with Viropil Tablet is highly dangerous and can cause life-threatening heart rhythm issues.
  • Metformin: Viropil Tablet can increase the levels of this diabetes medication in your blood, raising the risk of low blood sugar and lactic acidosis.
  • Anti-seizure medications (such as carbamazepine, phenobarbital, or phenytoin): These drugs can speed up how your body processes this medicine, making it less effective.
  • Rifampin: This tuberculosis treatment can lower the amount of Viropil Tablet in your body, rendering your HIV treatment less effective.

Drug-Drug Interactions

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How does the drug interact with Viropil Tablet:
Co-administration of Viropil Tablet with Adefovir dipivoxil may increase the risk or severity of kidney problems.

How to manage the interaction:
Combining Viropil Tablet with Adefovir dipivoxil can possibly result in an interaction, but it can be taken if a doctor has advised it. If you experience any symptoms such as increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, contact a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Viropil Tablet:
Co-administration of Acyclovir with Dolutegravir/ Tenofovir disoproxil / Lamivudine may increase the risk or severity of kidney problems.

How to manage the interaction:
Co-administration of Acyclovir with Viropil Tablet can result in an interaction, it can be taken when a doctor has advised it. Contact a doctor immediately if you experience decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Viropil Tablet:
Co-administration of Lithium carbonate with Viropil Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Although there is a possible interaction between Viropil Tablet with Lithium, you can take these medicines when prescribed by a doctor. Consult the doctor immediately if you experience symptoms such as increased or decreased urination, sudden weight gain or weight loss, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Viropil Tablet:
Co-administration of Viropil Tablet with Ganciclovir can increase the risk or severity of side effects like kidney damage.

How to manage the interaction:
Although taking Ganciclovir with Viropil Tablet together can cause an interaction, it can be taken if a doctor has suggested it. If you have symptoms like feeling gaining or losing weight suddenly, trouble breathing, bone or muscle pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Viropil Tablet:
Co-administration of Viropil Tablet with Didanosine can reduce the effectiveness of Viropil Tablet.

How to manage the interaction:
Although taking Viropil Tablet and Didanosine together can possibly result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Viropil Tablet:
Co-administration of Viropil Tablet with Calcium acetate can reduce the effectiveness of Viropil Tablet.

How to manage the interaction:
Taking Viropil Tablet with Calcium acetate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take dolutegravir at least two hours before or six hours after the calcium acetate dose. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Viropil Tablet:
Co-administration of Ketorolac with Viropil Tablet may increase the risk of developing kidney problems.

How to manage the interaction:
Although taking Ketorolac with Viropil Tablet together can possibly result in an interaction, it can be taken when a doctor has prescribed it. However, if you experience symptoms like increased or decreased urination, sudden weight gain or loss, shortness of breath, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Viropil Tablet:
Taking Viropil Tablet with Ferrous gluconate can reduce the effectiveness of Viropil Tablet.

How to manage the interaction:
Although taking Viropil Tablet and Ferrous gluconate together can possibly result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Viropil Tablet:
Co-administration of Viropil Tablet with Cyclophosphamide may increase the risk of developing kidney problems.

How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with Viropil Tablet if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of kidney damage such as loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath. Do not stop using any medication without consulting a doctor.
How does the drug interact with Viropil Tablet:
Co-administration of Diclofenac with Viropil Tablet may increase the risk of developing kidney problems.

How to manage the interaction:
There may be a possible interaction between Diclofenac and Viropil Tablet but they can be taken together if a doctor has prescribed them. However consult a doctor immediately if you experience symptoms such as such as loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip

Certain foods, beverages, and supplements may influence the safety or effectiveness of Viropil Tablet during treatment.

  • Alcohol: Regularly drinking alcohol while taking this medicine can increase your risk of liver damage and make side effects like dizziness and sleepiness worse.
  • St. John's Wort: This herbal supplement can significantly lower the levels of this medicine in your body, which may cause your treatment to fail.
DOLUTEGRAVIR-50MG+LAMIVUDINE-300MG+TENOFOVIR DISOPROXIL FUMARATE-300MGHerbal products/medicines
Moderate

Drug-Food Interactions

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DOLUTEGRAVIR-50MG+LAMIVUDINE-300MG+TENOFOVIR DISOPROXIL FUMARATE-300MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Consuming St.John's Wort with Viropil Tablet can increase the risk of side effects. Avoid consuming St.John's Wort with Viropil Tablet.

Habit Forming

No

Therapeutic Class

[ANTIRETROVIRAL AGENTS]

FAQs

Viropil Tablet is used to treat HIV infection.
Viropil Tablet contains Dolutegravir, Lamivudine, and Tenofovir disoproxil fumarate. Dolutegravir increases the immune cells that help fight infections in the body and decreases the amount of HIV in the blood. Lamivudine and Tenofovir disoproxil fumarate work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Viropil Tablet helps in treating HIV infection.
Do not stop taking Viropil Tablet without consulting your doctor as it may reduce the effectiveness of anti-HIV therapy. Continue taking Viropil Tablet for as long as your doctor has prescribed it to you to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Viropil Tablet .
Viropil Tablet might cause lactic acidosis (excess of lactic acid in the blood), a rare but severe side effect. Consult a doctor immediately if you experience stomach pain, vomiting, nausea, drowsiness, and deep rapid breathing, as these could be the signs of lactic acidosis.
Viropil Tablet may cause bone problems such as bone pain, softening or thinning of bone which might lead to bone fractures. A regular bone density test is advised while taking Viropil Tablet .
Antacids, laxatives, or other medicines containing magnesium, aluminium or buffered medicines (medicines used to neutralise stomach acids) should be taken 2 hours before and 6 hours after taking Viropil Tablet . Consult your doctor if you have any concerns.
You can take iron or calcium supplements with Viropil Tablet if you have taken Viropil Tablet with food. If you haven’t taken Viropil Tablet with food, take Viropil Tablet 2 hours before or 6 hours after taking iron or calcium supplements. Consult your doctor if you have any concerns.
It is best to limit or avoid alcohol while taking this medication. Alcohol can increase the risk of liver damage and worsen side effects like dizziness or drowsiness. Talk to your doctor about what is safe for you.
If you vomit within 1 hour of taking your tablet, take another dose as soon as possible. If it has been more than 1 hour since you took it, do not take an extra dose—just wait and take your next dose at your regular time. Talk to your doctor if you experience persistent vomiting.
No, Viropil Tablet does not cure HIV. However, it is highly effective at keeping the virus under control, lowering your viral load, and helping your immune system stay strong so you can live a long, healthy life. Talk to your doctor to learn more about managing your treatment.
You should consult your doctor immediately if you are pregnant or planning to become pregnant. Your doctor will weigh the benefits and risks of continuing this medication to protect your health and prevent passing the virus to your baby. Talk to your doctor for personalised advice.
Some clinical studies have shown that modern antiretroviral treatments, including components in Viropil Tablet , can lead to weight gain in some individuals. This is often a sign of returning health as your immune system recovers. Talk to your doctor for guidance on managing weight changes through diet and exercise.
Maintaining an undetectable viral load through consistent use of Viropil Tablet means there is effectively zero risk of sexually transmitting HIV to partners. However, using protection is still highly recommended to prevent other sexually transmitted infections (STIs) and unplanned pregnancies. Talk to your doctor about your options.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - VIR0105
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