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  3. Xenical Capsule 42's

Xenical Capsule 42's, Pack of 1 Tablet
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Xenical Capsule is used to treat obesity and help in weight loss. It is to be used along with a low-calorie diet and regular physical exercise. It contains Orlistat, which decreases the absorption of fat from the food you eat. Thus, fat passes through the gut and is excreted in the faeces, which makes the body unable to use fat as a source of energy or convert it into fat tissue. Thus, it helps in weight loss.

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Composition :

ORLISTAT-120MG

Manufacturer/Marketer :

USV Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Xenical Capsule

Xenical Capsule is used to treat obesity and help in weight loss. Xenical Capsule is to be used along with a low-calorie diet and regular physical exercise. Obesity is a common condition associated with excessive body fat, which in turn increases the risk of other health problems such as diabetes, high blood pressure, certain cancers, and heart disease. Intake of more calories than you burn by exercise or daily activities results in obesity.

Xenical Capsule contains Orlistat, which works in the small intestine and stomach and prevents the action of enzymes that break down fat, which is absorbed by the body. Xenical Capsule decreases the absorption of fat from the food you eat. Thus, fat passes through the gut and is excreted in the faeces, which makes the body unable to use fat as a source of energy or convert it into fat tissue. Thereby, Xenical Capsule helps in weight loss.

Take Xenical Capsule as prescribed by your doctor. You are advised to take Xenical Capsule for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience soft stools, sudden bowel motions, flatulence (gas) with or without oily spotting, oily or fatty stools, stomach pain, stool incontinence (involuntary leakage of stools), and runny or liquid stools. Most of these side effects of Xenical Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Xenical Capsule or any other medicines, please tell your doctor. Avoid taking Xenical Capsule if you are pregnant or planning for pregnancy, as it may cause fetal harm. It is not known whether Xenical Capsule is excreted in human milk. Therefore, please consult a doctor if you are a breastfeeding woman. Xenical Capsule is not recommended for children below 18 years of age, as the safety and effectiveness have not been established. You are advised to take a multivitamin containing fat-soluble vitamins such as A, D, E, and K at bedtime, as Xenical Capsule may reduce the absorption of certain vitamins in the body.

Uses of Xenical Capsule

Xenical Capsule is used in the management of obesity. The detailed uses of Xenical Capsule are as follows:

Manages Obesity: Xenical Capsule is used along with a low-calorie diet to promote weight loss in obese or overweight individuals by decreasing the absorption of fat from food and preventing excess fat accumulation in the body.

Prevents Weight Regain: Xenical Capsule supports long-term weight management by lowering the risk of regaining lost weight after initial weight loss.

Directions for Use

  • Xenical Capsule can be taken during, or up to 1 hour after meals, as advised by your doctor.
  • Take Xenical Capsule daily at the same time for effective results or as your doctor advises.
  • Swallow Xenical Capsule as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Xenical Capsule contains Orlistat, an anti-obesity medicine used to aid weight management in overweight and obese patients.
  • Blocks fat absorption: Acts in the stomach and small intestine to inhibit enzymes (lipases) responsible for breaking down dietary fat.
  • Reduces calorie intake from fat: Prevents the absorption of about 25–30% of the fat consumed in meals, allowing it to pass through the gut and be excreted.
  • Promotes safe weight loss: Helps achieve gradual weight reduction when combined with a calorie-controlled diet and regular physical activity.
  • Lowers obesity-related health risks: Reduces the risk of developing type 2 diabetes, high blood pressure, heart disease, and other weight-related conditions.
  • Supports long-term weight management: Helps maintain weight loss over time when used alongside lifestyle modifications under medical supervision.

How Xenical Capsule Works

Xenical Capsule contains Orlistat, which works in the small intestine and stomach and prevents the action of enzymes that break down fat, which is absorbed by the body. Xenical Capsule decreases the absorption of fat from the food you eat. Thus, fat passes through the gut and is excreted in the faeces, which makes the body unable to use fat as a source of energy or convert it into fat tissue. Thereby, Xenical Capsule helps in weight loss.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Xenical Capsule
  • If you notice your stools are bulky, frothy, greasy, floating, or foul-smelling, and have weight loss or cramps, consult your doctor right away.
  • Try to limit or avoid foods or drinks like whole nuts, butter, coconut and palm oils, red meat, coffee creamers, and alcohol.
  • Increase your intake of healthy fats in your diet, such as those from oily fish (like salmon and tuna), olive oil, and avocados.
  • Fatty stools can cause a lack of fat-soluble vitamins, so consider adding foods rich in vitamin A (fish oil, butter), vitamin D (fatty fish, mushrooms), vitamin E (sunflower seeds, almonds), and vitamin K (kale, spinach) to your meals.
  • If left untreated, fatty stools may lead to significant weight loss, malnutrition, and electrolyte imbalances, so have regular check-ups with your doctor, including nutritional assessments.
  • Tell your doctor about your gas symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage gas symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for gas symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Defecation urgency can bother you, and if this happens without a specific reason, consult your doctor.
  • Avoid infections that may frequently occur by maintaining good hygiene if you have an issue of frequent bowel movements.
  • Avoid eating fibre-containing foods, nuts and caffeine that make you feel like defecating.
  • Stay calm and do not smoke or drink alcohol, as it can worsen your condition.
  • Contract specific muscles near the anus that help to stop releasing the stool.
  • Try to stand or lie down instead of sitting for long hours if you have defecation urgency.
  • If you notice your stools are bulky, frothy, greasy, floating, or foul-smelling, and have weight loss or cramps, consult your doctor right away.
  • Try to limit or avoid foods or drinks like whole nuts, butter, coconut and palm oils, red meat, coffee creamers, and alcohol.
  • Increase your intake of healthy fats in your diet, such as those from oily fish (like salmon and tuna), olive oil, and avocados.
  • Fatty stools can cause a lack of fat-soluble vitamins, so consider adding foods rich in vitamin A (fish oil, butter), vitamin D (fatty fish, mushrooms), vitamin E (sunflower seeds, almonds), and vitamin K (kale, spinach) to your meals.
  • If left untreated, fatty stools may lead to significant weight loss, malnutrition, and electrolyte imbalances, so have regular check-ups with your doctor, including nutritional assessments.
  • If you notice your stools are bulky, frothy, greasy, floating, or foul-smelling, and have weight loss or cramps, consult your doctor right away.
  • Try to limit or avoid foods or drinks like whole nuts, butter, coconut and palm oils, red meat, coffee creamers, and alcohol.
  • Increase your intake of healthy fats in your diet, such as those from oily fish (like salmon and tuna), olive oil, and avocados.
  • Fatty stools can cause a lack of fat-soluble vitamins, so consider adding foods rich in vitamin A (fish oil, butter), vitamin D (fatty fish, mushrooms), vitamin E (sunflower seeds, almonds), and vitamin K (kale, spinach) to your meals.
  • If left untreated, fatty stools may lead to significant weight loss, malnutrition, and electrolyte imbalances, so have regular check-ups with your doctor, including nutritional assessments.
  • Increased defectaion can bother you, and if this happens without a specific reason, consult your doctor.
  • Avoid infections that may frequently occur by maintaining good hygiene if you have an issue of frequent bowel movements.
  • Do not eat fibre-containing foods, nuts and caffeine that make you feel like defecating.
  • Stay calm and do not smoke or drink alcohol, as it can worsen your condition.
  • Contract specific muscles near the anus that help to stop releasing the stool.
  • Try to stand or lie down instead of sitting for long hours if you have defecation urgency.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Xenical Capsule

Avoid taking extra doses, as doing so can lead to unwanted side effects. If an overdose is suspected, seek prompt medical assistance or contact the nearest poison control centre, even if you feel well.

Drug Warnings

  • Inform your doctor if you are allergic to Xenical Capsule or any other medicines.
  • Consult your doctor before taking Xenical Capsule if you have cholestasis (blocked bile flow from the liver), chronic malabsorption syndrome, anorexia, bulimia, thyroid disorder, diabetes, kidney problems, or liver problems.
  • Avoid taking Xenical Capsule if you are pregnant or planning to become pregnant, as it may cause harm to the unborn baby.
  • If you are breastfeeding, consult your doctor before using Xenical Capsule , as it is not known whether the medicine passes into breast milk.
  • Xenical Capsule is not recommended for children under 18 years of age due to a lack of established safety and effectiveness.
  • Combine Xenical Capsule with regular exercise and a low-fat, low-calorie diet for best results in weight management.
  • If you experience severe diarrhoea while taking Xenical Capsule , it may reduce the effectiveness of oral contraceptive pills. Use an additional contraceptive method to prevent pregnancy in such cases.
  • Take a daily multivitamin supplement containing fat-soluble vitamins (A, D, E, and K) at bedtime, at least 2 hours after Xenical Capsule , since the medicine may reduce the absorption of these vitamins.

Drug-Drug Interactions

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OrlistatCiclosporin
Severe
OrlistatKetoconazole
Severe

Drug-Drug Interactions

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OrlistatCiclosporin
Severe
How does the drug interact with Xenical Capsule:
Coadministration of Ciclosporin with Xenical Capsule can reduce the levels and effects of Ciclosporin.

How to manage the interaction:
Although there is a possible interaction between Xenical Capsule and Ciclosporin, you can take these medicines together when prescribed by your doctor. Do not stop using any medications without talking to a doctor.
OrlistatKetoconazole
Severe
How does the drug interact with Xenical Capsule:
Coadministration of Ketoconazole and Xenical Capsule can increase the risk of developing liver damage.

How to manage the interaction:
Although taking Ketoconazole and Xenical Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience fever, chills, joint pain, unusual bleeding, skin rash, lack of appetite, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
OrlistatCalcitriol
Severe
How does the drug interact with Xenical Capsule:
Co-administration of Xenical Capsule with Calcitriol may reduce the levels of Calcitriol which can lead to low treatment outcomes.

How to manage the interaction:
Although there is an interaction, Calcitriol can be taken with Xenical Capsule when prescribed by the doctor. Do not discontinue any medications without consulting a doctor.
OrlistatTeriflunomide
Severe
How does the drug interact with Xenical Capsule:
Co-administration of Teriflunomide and nintedanib can increase the risk of developing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Nintedanib can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, skin rash, loss of appetite, fatigue, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
OrlistatLomitapide
Severe
How does the drug interact with Xenical Capsule:
Co-administration of Lomitapide and Xenical Capsule can increase the risk of developing liver problems.

How to manage the interaction:
Co-administration of Lomitapide and Xenical Capsule can lead to an interaction, it can be taken when advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, vomiting, abdominal pain, dark-coloured urine, light-coloured stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
OrlistatMipomersen
Severe
How does the drug interact with Xenical Capsule:
Co-administration of Mipomersen and Xenical Capsule can increase the risk of developing liver problems.

How to manage the interaction:
Co-administration of Mipomersen and Xenical Capsule can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, skin rash, loss of appetite, fatigue, vomiting, abdominal pain, dark-coloured urine, light-coloured stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
OrlistatLeflunomide
Severe
How does the drug interact with Xenical Capsule:
Co-administration of leflunomide and Xenical Capsule can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Xenical Capsule can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a low-fat, balanced diet where no more than 30% of calories come from fat to minimise side effects like oily stools. Choose lean meats, fish, low-fat dairy, whole grains, vegetables, and fruits.
  • Distribute fat intake evenly throughout the day to avoid digestive discomfort caused by excessive fat intake in a single meal.
  • Avoid high-fat, fried, or greasy foods, as these can increase gastrointestinal side effects while taking Xenical Capsule .
  • Take a multivitamin supplement at bedtime, at least two hours apart from Xenical Capsule , since the medicine may reduce the absorption of vitamins A, D, E, and K.
  • Stay hydrated by drinking sufficient water throughout the day to support digestion and prevent constipation.
  • Engage in regular physical activity, aiming for at least 150 minutes of moderate exercise per week to aid weight loss and improve overall health.
  • Limit or avoid alcohol intake as it adds extra calories and may slow down your weight-loss progress.
  • Monitor your weight and overall health regularly and follow up with your doctor to track treatment effectiveness.
  • Eat small, frequent meals to help control hunger and maintain stable energy levels.
  • Take Xenical Capsule as advised by the doctor, and do not skip, double, or change your dose without medical advice.

Habit Forming

No

Therapeutic Class

ANTIOBESITY DRUG

Xenical Capsule Substitute

Substitutes safety advice

Product Substitutes

bannner image

Alcohol

Caution

Alcohol should be limited or avoided while taking Orlistat to support weight loss goals and overall health.

bannner image

Pregnancy

Unsafe

Xenical Capsule is a Category X pregnancy drug and is considered unsafe for pregnant women as it may cause harm to the unborn baby. So, if you are pregnant or planning for pregnancy, please inform your doctor before taking Xenical Capsule .

bannner image

Breast Feeding

Caution

It is unknown whether Xenical Capsule is excreted in human milk. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.

bannner image

Driving

Safe if prescribed

Xenical Capsule usually does not affect your ability to drive or operate machinery.

bannner image

Liver

Caution

Take Xenical Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Caution

Take Xenical Capsule with caution, especially if you have a history of Kidney diseases/conditions. Xenical Capsule may cause kidney stones in patients suffering from chronic kidney disease. Please consult a doctor if you have kidney problems so that the dose may be adjusted by your doctor as required.

bannner image

Children

Unsafe

Xenical Capsule is not recommended for children below 18 years of age, as the safety and effectiveness have not been established.

Have a query?

FAQs

Xenical Capsule is used to treat obesity and help in weight loss. It is to be used along with a low-calorie diet and regular physical exercise.

Xenical Capsule contains Orlistat, which works in the small intestine and stomach and inhibits the action of enzymes that break down fat, which is absorbed by the body. Xenical Capsule decreases the absorption of fat from the food you eat. Thus, fat passes through the gut and is excreted in the faeces, which makes the body unable to use fat as a source of energy or convert it into fat tissue. Thereby, Xenical Capsule helps in weight loss.

You are not recommended to take Xenical Capsule with ciclosporin (used for organ transplant rejections, severe rheumatoid arthritis) as it may reduce the effectiveness of ciclosporin. However, if you are supposed to take both medicines, you are advised to take ciclosporin after 3 hours of taking Xenical Capsule . However, please consult a doctor before taking Xenical Capsule with any other medicines.

Xenical Capsule may cause kidney stones in patients suffering from chronic kidney disease. Therefore, if you have any kidney problems, please inform your doctor before taking Xenical Capsule .

Xenical Capsule should be used with caution in diabetic patients as it may increase the risk of low blood sugar levels. Therefore, inform your doctor if you have diabetes before taking Xenical Capsule so that the dose of antidiabetic medicine may be adjusted accordingly.

You are recommended to avoid high-fat meals that include butter, meat, dark chocolate, olive oil, nuts and seeds (brazil nuts) with Xenical Capsule as it may increase the risk of adverse effects on the stomach or intestines.

You are recommended to use Xenical Capsule for as long as your doctor has prescribed it. However, avoid taking Xenical Capsule for more than 6 months. If you do not notice weight loss after taking Xenical Capsule for 12 weeks, please consult a doctor.

You are recommended to take a multivitamin containing fat-soluble vitamins such as A, D, E and K at bedtime or at least 2 hours after taking Xenical Capsule . Generally, Xenical Capsule may reduce the absorption of certain vitamins in the body. Therefore, your doctor may advise you to take multivitamins.

Do not take Xenical Capsule if you are allergic to any of its components or if you have cholestasis (bile flow from the liver is blocked) or chronic malabsorption syndrome.

Follow a low-calorie diet and regular physical exercise. Include fruits, vegetables and whole grains in your diet.

Interaction of Xenical Capsule with alcohol is unknown. Please consult a doctor before consuming alcohol while using Xenical Capsule .

Xenical Capsule starts working within 2 weeks and you may notice results in 1-3 months.

Yes, it is important to do regular exercise and maintain a low-fat and low-calorie diet along with Xenical Capsule for effective results.

Xenical Capsule should be swallowed as a whole with water; do not crush or chew it. Take it during a meal or up to 1 hour after a meal.

Xenical Capsule may cause side effects like soft stools, sudden bowel motions, flatulence (gas) with or without oily spotting, oily or fatty stools, stomach pain, stool incontinence (involuntary leakage of stools), and runny or liquid stools. If the side effects persist, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

1503, 15th Floor, ?The Capital?, Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051
Other Info - XEN0009

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Aug 4, 2025 | 2:13 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.6533.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020766s029lbl.pdf

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