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Composition :

ONDANSETRON-2MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Zofer Syrup

Zofer Syrup is an antiemetic medicine. It is used in the treatment of paediatric gastroenteritis in infants and children aged 6 months to 12 years. It is also used in the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy in children aged six months and above. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the natural response to the body to forcefully discharge the stomach contents.

Zofer Syrup contains 'Ondanestron', which belongs to serotonin 5-HT3 receptor antagonists. It works by blocking the action of a chemical called serotonin in the body, which is responsible for causing nausea and vomiting. As a result, Zofer Syrup prevents the sensation of nausea and vomiting caused by cancer chemotherapy.

Zofer Syrup may cause certain side effects in your child, such as feeling of warmth, headache, diarrhoea, and stomach pain. These side effects generally resolve over time. However, if it does not resolve, stop giving this medicine to your child and contact the paediatrician. Do not give more than the prescribed dose of Zofer Syrup to the child. Zofer Syrup can be given with or without food. The dose of the medicine will be decided by your paediatrician.

Zofer Syrup is intended for paediatric use only. Avoid giving Zofer Syrup to your child if he/she is allergic to it. Keep your doctor informed about your child’s health condition, including his current medications and medical history, to rule out any side effects/interactions. Before administration, inform your doctor if your child has liver and kidney disease.

Uses of Zofer Syrup

Zofer Syrup is used in the prevention of Nausea and Vomiting. The detailed uses of Zofer Syrup are as follows:
•Postoperative Nausea and Vomiting Relief: Zofer Syrup is commonly used to alleviate nausea and vomiting experienced by patients after surgical procedures, often caused by anesthesia.
•Supportive Care in Palliative Settings: Zofer Syrup provides relief for nausea and vomiting in palliative care patients, helping to improve comfort amidst challenges from underlying conditions or treatment side effects.

Directions for Use

Zofer Syrup is an oral solution (Oral drops). Shake the container well before each use. Measure the prescribed solution of Zofer Syrup and administer them to your child. It is advised to measure the quantity accurately with the help of a dropper.

Medicinal Benefits

Zofer Syrup contains 'Ondanestron' that belongs to serotonin 5-HT3 receptor antagonists. It works by blocking the action of a chemical called serotonin in the body which is responsible for causing nausea and vomiting. As a result, Zofer Syrup prevents the sensation of nausea and vomiting caused due to cancer chemotherapy.

How Zofer Syrup Works

Zofer Syrup contains 'Ondanestron', which belongs to serotonin 5-HT3 receptor antagonists. It works by blocking the action of a chemical called serotonin in the body, which is responsible for causing nausea and vomiting. As a result, Zofer Syrup prevents the sensation of nausea and vomiting caused by cancer chemotherapy.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zofer Syrup 30 ml
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Contact your physician right away if you suffer from hypoxia symptoms including chest pain, disorientation, or shortness of breath.
  • Your doctor can monitor your progress and modify treatment programs with the help of routine follow-up sessions.
  • Omega-3 supplements may support the transport of oxygen to tissues.
  • Regular exercise improves cardiovascular health and boosts oxygen delivery to tissues.
  • Quit smoking, as it can worsen hypoxia.

What if I have taken an overdose of Zofer Syrup

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Zofer Syrup may include constipation, dizziness or lightheadedness, fainting, irregular heartbeat, and sudden loss of vision for a short time. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Avoid giving Zofer Syrup to your child if he/she is allergic to it. Keep your doctor informed about your child’s health condition including his current medications and medical history to rule out any side effects/interactions. Before administration, inform your doctor if your child has liver and kidney disease. This medicine is intended for only paediatric population. Hence not recommended for use in special population (pregnant, breastfeeding mothers) and adults.

Drug-Drug Interactions

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OndansetronAnagrelide
Severe

Drug-Drug Interactions

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How does the drug interact with Zofer Syrup 30 ml:
Taking Zofer Syrup 30 ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Zofer Syrup 30 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronAnagrelide
Severe
How does the drug interact with Zofer Syrup 30 ml:
Taking Zofer Syrup 30 ml with anagrelide increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Zofer Syrup 30 ml alongside anagrelide can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zofer Syrup 30 ml:
When Vilazodone is taken with Zofer Syrup 30 ml, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Zofer Syrup 30 ml, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zofer Syrup 30 ml:
Using Tapentadol together with Zofer Syrup 30 ml might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although taking Zofer Syrup 30 ml along with tapentadol can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zofer Syrup 30 ml:
When Zofer Syrup 30 ml, is taken with Vortioxetine it can cause serotonin syndrome (A condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Zofer Syrup 30 ml along with Vortioxetine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zofer Syrup 30 ml:
When Zofer Syrup 30 ml, is taken with furazolidone it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Zofer Syrup 30 ml along with furazolidone can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zofer Syrup 30 ml:
Using Zofer Syrup 30 ml together with Sumatriptan might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Co-administration of Zofer Syrup 30 ml along with sumatriptan can lead to an interaction, it should be taken only if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zofer Syrup 30 ml:
Taking Zofer Syrup 30 ml with Iloperidone increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Zofer Syrup 30 ml along with Iloperidone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zofer Syrup 30 ml:
Taking Zofer Syrup 30 ml and Sotalol can increase the risk or severity of irregular heart rhythms which can be severe.

How to manage the interaction:
Although taking Zofer Syrup 30 ml and Sotalol can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zofer Syrup 30 ml:
When Zofer Syrup 30 ml is taken with paroxetine, can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Zofer Syrup 30 ml along with paroxetine can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Certain food items/medicines are known to cause nausea/vomiting to your child.
  • Make your child drink more fluids to avoid dehydration.
  • Making your child take a healthy diet that includes lots of fruits and vegetables, nuts, and low-fat dairy products will help to keep your child in good health and avoid chances of nausea and vomiting. 
  • Avoid giving greasy or oily foods to your child as this food triggers nausea and vomiting. 

Habit Forming

No

Therapeutic Class

ANTIEMETICS
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Caution

If your child has a liver impairment, consult your doctor before using this medicine. Your doctor may weigh the benefits and risks before prescribing Zofer Syrup.

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Kidney

Caution

If your child has a kidney impairment, consult your doctor before using this medicine. Your doctor may weigh the benefits and risks before prescribing Zofer Syrup.

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Children

Safe if prescribed

Zofer Syrup is safe for use in children if prescribed by the doctor. The dose of the medicine will be decided by your paediatrician. Do not give more than the recommended dose to your child.

Have a query?

FAQs

Zofer Syrup is an antiemetic medicine. It is used in the treatment of paediatric gastroenteritis in infants and children aged 6 months to 12 years. It is also used in the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy in children aged six months and above.

Zofer Syrup contains 'Ondanestron' that belongs to serotonin 5-HT3 receptor antagonist. It works by blocking the action of a chemical called serotonin in the body, which is responsible for nausea and vomiting.

Use it for as long as your paediatrician suggested.

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Other Info - ZOF0088

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