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  3. Zolcalm-10 Tablet 10's

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Zolcalm-10 Tablet 10's, Pack of 10
Zolcalm-10 Tablet 10's, Pack of 10
Zolcalm-10 Tablet 10's, Pack of 10
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Zolcalm-10 Tablet is used in the treatment of insomnia. It contains Zolpidem and Melatonin which relaxes muscles, reduces anxiety, and helps to fall asleep. It may cause side effects such as nausea, headache, diarrhoea, drowsiness, and dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

MELATONIN-3MG + ZOLPIDEM-10MG

Manufacturer/Marketer :

Linux Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Zolcalm-10 Tablet

Zolcalm-10 Tablet is a combination medication containing 'sedative-hypnotics' used in the treatment of insomnia. Insomnia is a disorder of sleep that causes difficulty in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature due to various complications like stress, anxiety, and breathing problems.

Zolcalm-10 Tablet contains Zolpidem and Melatonin, primarily used to treat insomnia. Zolpidem works by increasing the activity of GABA, which is a chemical messenger in the brain, acting as a natural nerve-calming agent, thereby inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep).  Thus, Zolcalm-10 Tablet relaxes muscles, reduces anxiety, and helps to fall asleep.

Take Zolcalm-10 Tablet as prescribed by your doctor. You are advised to take Zolcalm-10 Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. Preferably take Zolcalm-10 Tablet empty stomach and just before bedtime. In some cases, you may experience nausea, headache, diarrhoea, drowsiness, and dizziness. Most of these side effects of Zolcalm-10 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are pregnant, planning to become pregnant, or breastfeeding, please inform your doctor before starting Zolcalm-10 Tablet . Do not stop taking Zolcalm-10 Tablet even if you feel better, as it may lead to unpleasant side effects. Zolcalm-10 Tablet is known to cause drowsiness, so do not drive or operate machinery. Avoid consumption of alcohol as it may reduce the effectiveness of Zolcalm-10 Tablet . Zolcalm-10 Tablet should not be used for daily naps.

Uses of Zolcalm-10 Tablet

Treatment of Insomnia (sleeplessness).

Directions for Use

• Take Zolcalm-10 Tablet with or without food or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Zolcalm-10 Tablet is a sleeping pill used to treat insomnia (difficulty in falling or staying asleep). Zolpidem increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep). Thus, Zolcalm-10 Tablet relaxes muscles, reduces anxiety, and helps to fall asleep. Appropriate lifestyle changes are recommended along with Zolcalm-10 Tablet to improve the quality of sleep.

How Zolcalm-10 Tablet Works

Zolcalm-10 Tablet contains Zolpidem and Melatonin, primarily used to treat insomnia. Zolpidem works by increasing the activity of GABA, which is a chemical messenger in the brain, acting as a natural nerve-calming agent, thereby inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep).  Thus, Zolcalm-10 Tablet relaxes muscles, reduces anxiety, and helps to fall asleep.

Storage

Keep Zolcalm-10 Tablet out of the sight and reach of children.
Side effects of Zolcalm-10 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Zolcalm-10 Tablet

Do not take more than the prescribed dose of Zolcalm-10 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Zolcalm-10 Tablet if you are allergic to Zolcalm-10 Tablet or any of its ingredients. If you notice that the tablets are not working as well as they did in the beginning of the treatment, please consult a doctor as you might have developed tolerance to Zolcalm-10 Tablet , and dose adjustment may be required. Zolcalm-10 Tablet contains Zolpidem, a category C pregnancy drug, and is not recommended for use during pregnancy as it may cause adverse effects in the baby after birth. If you are a breastfeeding mother, it is advised to consult a doctor before using Zolcalm-10 Tablet . If you have kidney, liver, or breathing problems, severe muscle weakness, sleep apnoea (a severe condition in which breathing stops and starts repeatedly in sleep), and if you have a history of depression or mental illness, please inform your doctor before taking Zolcalm-10 Tablet . Maintain a time gap of a minimum of 8 hours between taking Zolcalm-10 Tablet and driving to reduce the risk of increased adverse effects.

Drug-Drug Interactions

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ZolpidemSodium oxybate
Critical
ZolpidemCodeine
Severe

Drug-Drug Interactions

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ZolpidemSodium oxybate
Critical
How does the drug interact with Zolcalm-10 Tablet:
Using sodium oxybate together with Zolcalm-10 Tablet can significantly increase the risk of severity of low blood pressure, breathing difficulties, fainting and unconsciousness.

How to manage the interaction:
Taking Sodium oxybate with Zolcalm-10 Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate consult a doctor immediately. You should refrain from operating any dangerous machinery or driving a car. Do not stop using any medications without talking to a doctor.
ZolpidemCodeine
Severe
How does the drug interact with Zolcalm-10 Tablet:
Using Zolcalm-10 Tablet together with Codeine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking codeine and Zolcalm-10 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. Do not discontinue any medications without consulting a doctor.
ZolpidemMethadone
Severe
How does the drug interact with Zolcalm-10 Tablet:
Using Zolcalm-10 Tablet together with Methadone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Methadone and Zolcalm-10 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemPindolol
Severe
How does the drug interact with Zolcalm-10 Tablet:
Taking Zolcalm-10 Tablet with Pindolol may increase the risk of low blood pressure.

How to manage the interaction:
Although taking Pindolol and Zolcalm-10 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
ZolpidemTapentadol
Severe
How does the drug interact with Zolcalm-10 Tablet:
Using Zolcalm-10 Tablet together with Tapentadol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Zolcalm-10 Tablet with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemButorphanol
Severe
How does the drug interact with Zolcalm-10 Tablet:
Using Zolcalm-10 Tablet together with Butorphanol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Butorphanol and Zolcalm-10 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, or reaction speed, avoid driving or operating hazardous machinery consult a doctor. Do not stop using any medications without a doctor's advice.
ZolpidemOxycodone
Severe
How does the drug interact with Zolcalm-10 Tablet:
Using Zolcalm-10 Tablet together with Oxycodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Oxycodone and Zolcalm-10 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemMorphine
Severe
How does the drug interact with Zolcalm-10 Tablet:
Using Zolcalm-10 Tablet together with Morphine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Morphine and Zolcalm-10 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemEsketamine
Severe
How does the drug interact with Zolcalm-10 Tablet:
Taking Zolcalm-10 Tablet with Esketamine increases the effects of Zolcalm-10 Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Esketamine and Zolcalm-10 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should wait until the following day to operate any dangerous machinery or drive a car. Do not discontinue any medications without consulting a doctor.
ZolpidemCiprofloxacin
Severe
How does the drug interact with Zolcalm-10 Tablet:
Coadministration of Zolcalm-10 Tablet with ciprofloxacin can increase the blood levels and effects of Zolcalm-10 Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking ciprofloxacin and Zolcalm-10 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience drowsiness, dizziness, or sleep disturbances, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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MELATONIN-3MG+ZOLPIDEM-10MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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MELATONIN-3MG+ZOLPIDEM-10MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking caffeine with Zolcalm-10 Tablet may increase the blood levels and effects of Zolcalm-10 Tablet. Avoid taking excessive caffeine consumption while being treated with Zolcalm-10 Tablet.

Diet & Lifestyle Advise

  • Do regular exercise during day time.
  • Do not take a nap during day time. Set regular timings to go to bed and wake up.
  • Relax at least 1 hour before bedtime by bathing with warm water, listening to music, or reading a book.
  • Make the bedroom dark and quiet, and ensure that your pillows and mattresses are comfortable.
  • Avoid watching tv, using mobiles or laptops just before bedtime.
  • Limit caffeine intake, including tea, coffee, hot chocolate, cola, and energy drinks, as it may reduce the effectiveness of Zolcalm-10 Tablet .
  • Avoid alcohol consumption as it may increase the risk of psychomotor impairment (slowdown of thought process and reduced physical movements), dependence, sleepwalking, or sleep-driving.

Habit Forming

Yes

Therapeutic Class

SEDATIVE-HYPNOTIC DRUGS

Zolcalm-10 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol with Zolcalm-10 Tablet as it may increase the risk of dependence, psychomotor impairment (slowdown of thought process, and reduced physical movements), sleepwalking, or sleep-driving.

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Pregnancy

Unsafe

Zolcalm-10 Tablet contains Zolpidem, a Category C pregnancy drug, and is not recommended for use during pregnancy as it may cause adverse effects in the baby after birth.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Zolcalm-10 Tablet as it may be excreted in breast milk.

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Driving

Unsafe

You may experience dizziness, drowsiness, confusion, decreased alertness, blurred, or double vision, especially the day after taking Zolcalm-10 Tablet . Therefore, avoid driving if you feel drowsy or dizzy after taking Zolcalm-10 Tablet .

bannner image

Liver

Caution

Take Zolcalm-10 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Zolcalm-10 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Caution

Zolcalm-10 Tablet is not recommended for children below 18 years of age.

Health Queries

What the time period with sleep this pill

Dr Bayyarapu Kumar

Dr Bayyarapu Kumar

M Pharmacy

After taking Zolcalm-10 Tablet (Melatonin 3 mg + Zolpidem 10 mg), you should aim for at least 6 to 8 hours of uninterrupted sleep for it to work effectively and to avoid next-day drowsiness or dizziness. The exact duration may vary from person to person depending on factors like age, overall health, other medications, and individual sensitivity to the drug.

Have a query?

FAQs

Zolcalm-10 Tablet is used in the treatment of insomnia.

Zolcalm-10 Tablet is a sleeping pill used to treat insomnia (difficulty in falling or staying asleep). Zolpidem increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep)

No, Zolcalm-10 Tablet is not recommended for depression patients as it may worsen the condition and increase self-harming or suicidal thoughts. Therefore, if you are suffering from depression or have a history of depression, please inform your doctor before taking Zolcalm-10 Tablet .

You are recommended to take Zolcalm-10 Tablet just before bedtime as it helps to sleep quickly and improves sleep quality. If you forget to take Zolcalm-10 Tablet at night, do not take it in the day time as it may cause drowsiness, confusion and dizziness.

No, you are not recommended to take Zolcalm-10 Tablet with hydrocodone or other opioid pain killers such as oxycodone, naloxone, and tramadol as co-administration of these medicines with Zolcalm-10 Tablet may increase the risk of difficulty in breathing, drowsiness, coma, and even death. However, before using Zolcalm-10 Tablet with any other medicines, you are advised to contact your doctor so that the dose may be adjusted to use safely.

Yes, Zolcalm-10 Tablet may cause dependence (mental and physical effects caused due to compulsion of taking Zolcalm-10 Tablet ) if used in high doses and for a prolonged time. This risk of dependency on Zolcalm-10 Tablet increases in patients who have a history of drug or alcohol abuse.

Country of origin

INDIA

Manufacturer/Marketer address

Plot no: 492, Viduthalai Nagar Extension Near JD Mahal, Pallavaram Thuraipakam Road S.Kulathur,Kovilambakkam, Chennai - 600 117
Other Info - ZOL0174

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:45 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/019908s027lbl.pdf
  2. https://www.drugs.com/zolpidem.html
  3. https://www.nhs.uk/medicines/zolpidem/
  4. https://www.medicines.org.uk/emc/files/pil.10405.pdf

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