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compositionComposition:IBUPROFEN-400MG
prescription
Prescription Medicine
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Brufen 400 Tablet 20's is used to relieve mild to moderate pain, inflammation, and fever in adults and paediatrics above 6 months of age. It helps to treat conditions such as menstrual cramps, headache, neuralgia (nerve-related pain), migraine, back pain, dental pain, swelling and stiffness in joints and muscles, cold, and flu symptoms. It contains Ibuprofen, which works by reducing the production of chemicals prostaglandins that are produced at injury sites and cause pain and swelling. Thus, it reduces mild to moderate pain, inflammation, and fever. In some cases, you may experience certain common side effects such as indigestion, diarrhoea, constipation, flatulence (gas), general weakness, and dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

IBUPROFEN-400MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Brufen 400 Tablet 20's

Brufen 400 Tablet 20's is a non-steroidal anti-inflammatory drug (NSAID) widely used to relieve mild to moderate pain, reduce inflammation, and lower fever. It helps manage painful conditions such as headaches, toothaches, muscle aches, back pain, and menstrual cramps. By targeting the source of discomfort, it allows you to comfortably carry out your daily activities.

For acute pain, you should take this medicine only when needed, while chronic conditions may require regular scheduled doses as advised by your doctor. It is highly recommended to take Brufen 400 Tablet 20's with food or a glass of milk to protect your stomach from irritation. Incorporating gentle daily stretching and staying well-hydrated can also significantly improve your recovery and joint comfort.

Most people tolerate this medication well, though minor issues like a mild upset stomach or heartburn can sometimes occur. If you notice serious symptoms like severe abdominal pain, black or tarry stools, or sudden shortness of breath, stop taking the medicine and consult your doctor immediately.

Before using Brufen 400 Tablet 20's, talk to your doctor if you have a history of stomach ulcers, high blood pressure, asthma, or kidney disease. Do not take this if you are in your third trimester of pregnancy, have severe heart failure, or have a history of allergic reactions to similar pain relievers.

Drinking alcohol while taking this medicine increases your risk of stomach bleeding, and smoking can further irritate your digestive tract. It is also important to consult your doctor before use if you are pregnant, breastfeeding, or elderly, as special precautions or alternative treatments may be necessary.

Uses of Brufen 400 Tablet 20's

Brufen 400 Tablet 20's is used to relieve pain, reduce inflammation, and lower fever in various conditions. The uses of Brufen 400 Tablet 20's are as follows: 

  • Mild to moderate pain: Brufen 400 Tablet 20's helps reduce localized discomfort from headaches, toothaches, and muscle strains by blocking pain signals.
  • Inflammatory arthritis: Brufen 400 Tablet 20's helps decrease joint swelling, stiffness, and pain associated with rheumatoid arthritis and osteoarthritis.
  • Fever reduction: Brufen 400 Tablet 20's helps lower elevated body temperature by regulating the body's internal thermostat during infections or illnesses.
  • Menstrual cramps: Brufen 400 Tablet 20's helps relieve painful uterine contractions and cramps experienced during menstrual cycles.

Key Benefits

Brufen 400 Tablet 20's offers effective, fast-acting relief that helps you return to your normal routine without being held back by discomfort. The key benefits of Brufen 400 Tablet 20's include:

  • Rapid Pain Relief: It starts working quickly to ease sudden aches, helping you manage acute pain effectively.
  • Improved Mobility: By reducing swelling and stiffness in the joints and muscles, it supports easier, pain-free movement.
  • Effective Fever Control: It brings down high temperatures reliably, making you feel more comfortable when recovering from an illness.
Side effects of Brufen 400 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Eosinophil levels can be lowered by eating fruits and vegetables, avoiding smoking, and consuming alcohol in moderation.
  • Several foods, such as ginger, garlic, pepper, turmeric, and honey, might boost immunity.
  • Avoid dairy products, including cheese, yoghurt, and milk.
  • Drink water and keep yourself hydrated.

Directions for Use

Always follow your doctor's exact instructions when taking this medication. Here are the standard guidelines for taking Brufen 400 Tablet 20's:

  • Swallow the tablet or capsule whole with a full glass of water. Do not crush, chew, or break it unless specifically instructed by your healthcare provider.
  • Take this medicine with food, a meal, or a glass of milk to minimise the risk of stomach irritation.
  • Use the lowest effective dose for the shortest duration necessary to relieve your symptoms.
  • If you are using the liquid suspension form, shake the bottle well before measuring each dose with a proper medical measuring spoon or cup.

How Brufen 400 Tablet 20's Works

Ibuprofen in Brufen 400 Tablet 20's belongs to a class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). When your body experiences injury or inflammation, it produces natural chemicals called prostaglandins, which contribute to pain, swelling, and fever. This medicine works by blocking cyclooxygenase (COX) enzymes that are involved in prostaglandin production. It inhibits both COX-1 and COX-2 enzymes, helping reduce inflammation, relieve pain, and lower fever. Because COX-1 also helps protect the stomach lining, blocking this enzyme may contribute to stomach-related side effects such as irritation, heartburn, or ulcers in some people.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Brufen 400 Tablet 20's. Alcohol intake, along with Brufen 400 Tablet 20's, may cause increased drowsiness and the risk of gastrointestinal ulcers and bleeding.

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Pregnancy

Unsafe

It is not recommended to take Brufen 400 Tablet 20's while you are pregnant, especially in the last trimester. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe you Brufen 400 Tablet 20's only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Brufen 400 Tablet 20's may pass into breast milk. Please consult your doctor if you have any concerns regarding this; your doctor will decide whether breastfeeding mothers can take Brufen 400 Tablet 20's or not.

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Driving

Caution

Brufen 400 Tablet 20's may cause drowsiness, dizziness, tiredness, and vision disturbances in some cases. So, avoid driving or operating heavy machinery if you experience any of these symptoms.

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Liver

Caution

Dose adjustment may be needed. Brufen 400 Tablet 20's should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Brufen 400 Tablet 20's should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Brufen 400 Tablet 20's is not recommended for children below six months of age, as the efficacy and safety have not been established.

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Heart

Unsafe

Brufen 400 Tablet 20's should be avoided in cardiac patients as it can lead to serious cardiavascular risks

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Geriatrics

Consult your doctor

Please consult a doctor before giving Brufen 400 Tablet 20's to geriatric patients.

What if I have taken an overdose of Brufen 400 Tablet 20's

If you suspect an overdose, seek immediate medical attention or call your local poison control centre. Symptoms of an overdose may include severe stomach pain, extreme drowsiness, breathing difficulties, or a ringing sensation in your ears.

Diet & Lifestyle Advise

  • Protect your stomach: Eat a small meal or snack rich in complex carbohydrates, like oatmeal or crackers, right before taking Brufen 400 Tablet 20's to coat your stomach lining.
  • Stay hydrated: Drink plenty of water throughout the day. Staying well-hydrated helps your kidneys process the medication safely and reduces the risk of kidney strain.
  • Limit sodium intake: Since this class of medicine can sometimes cause fluid retention, reducing salt in your diet can help prevent swelling in your feet and ankles.
  • Incorporate anti-inflammatory foods: Support your body's recovery by eating foods rich in antioxidants and omega-3 fatty acids, such as leafy greens, berries, and fatty fish.
  • Stay hydrated during illness: If you have vomiting, diarrhoea, fever, or other conditions that may cause dehydration, ensure you drink adequate fluids. Dehydration can increase the risk of kidney-related side effects while taking Brufen 400 Tablet 20's. Consult your doctor if you are unable to maintain adequate fluid intake. 

Health Queries

What stronger painkillers or remedies can I use to help me stand and walk again, since my heel tendon pain has returned after heavy exercise and has not improved after two days of taking Brufen 400 mg three times daily, icing, and wrapping it?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

Since you are already taking Brufen (ibuprofen) at a standard dose, please do not increase it without medical supervision. For additional relief, you can temporarily add paracetamol alongside the Brufen, as they target pain differently. However, because this pain is preventing you from walking, it is very important to rest and avoid putting weight on your foot. Please consult a doctor or physical therapist to examine your tendon, as you may need a specialized recovery plan or a supportive boot rather than simply stronger medication.

What should I do for one-sided back pain and an inability to bend down caused by exercising a few days ago, especially since taking Brufen and using Moov spray has not provided any relief?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

It is very common to strain a muscle or ligament during exercise, which can make bending very difficult. Since Brufen (ibuprofen) and Moov spray haven't provided relief, please avoid strenuous movements or heavy lifting, but try to walk gently rather than staying strictly in bed. Applying a warm compress may help relax the tight muscles. Because the pain is persistent, I highly recommend consulting a doctor or physical therapist for a proper evaluation. They can guide you on safe recovery exercises.

Is it safe to take Brufen when my period starts to help with body aches, tiredness, and severe mood swings that begin a few days before, and are there other medications you would recommend for these symptoms?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

It is generally safe and very effective to take Brufen (ibuprofen) at the start of your period to help relieve body aches and cramps. However, while ibuprofen is great for physical pain, it won't address tiredness or mood swings. For these premenstrual symptoms, lifestyle adjustments like regular gentle exercise, quality sleep, and a balanced diet can make a big difference. Additionally, daily supplements like calcium or vitamin B6 might help stabilize your mood and energy. Please consult your doctor if the mood swings feel overwhelming, as they can discuss other tailored options to support you.

How can I treat severe stomach issues and headaches that have lasted for four years and are not getting better with Brufen 400 and Famtac 40?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

Long-term use of Brufen (ibuprofen) can actually cause or worsen severe stomach issues, like gastritis or ulcers, while also leading to rebound headaches. While Famtac (famotidine) helps reduce stomach acid, it may not be enough to counteract the irritation from Brufen. I gently recommend discussing this with a doctor to safely taper off Brufen and explore alternative pain relief. Please consider seeing a gastroenterologist for your stomach and a neurologist for your headaches to find a safer, more effective long-term treatment plan.

I have back pain that has now radiated to my ankle. What medication or treatment should I take for relief?

Veda Maddala

Veda Maddala

M Pharmacy

This sounds like sciatica, where a nerve in your lower back is irritated. For temporary relief, you can try over-the-counter anti-inflammatories like ibuprofen or naproxen, or acetaminophen for pain. Alternating ice packs and gentle heat on your lower back can also help ease the discomfort. Try to stay active with light walking and avoid prolonged bed rest. Since the pain reaches your ankle, please consult a healthcare professional for a proper evaluation. They may suggest physical therapy or prescription treatments. Seek immediate medical care if you experience sudden leg weakness, numbness in your groin, or loss of bowel or bladder control.
health query

Have a query?

How Soon It Starts Working

The time required for Brufen 400 Tablet 20's to start to work: Brufen 400 Tablet 20's ideally shows its action within 30 to 60 minutes after administration. The time for which the effects of Brufen 400 Tablet 20's last: The effect of Brufen 400 Tablet 20's lasts for 4 to 6 hours.

What if you forget to take Brufen 400 Tablet 20's

If you take this medication on a regular schedule and miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular routine. Do not take a double dose to make up for a missed one.

Storage

• Store Brufen 400 Tablet 20's at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the medication in its original container, tightly closed, to protect it from moisture and direct light.

Drug Warnings

  • Avoid doubling up on pain relievers: Do not take other over-the-counter pain medications, cold formulas, or fever reducers containing similar ingredients without consulting your pharmacist first.
  • Monitor your blood pressure: This medication can occasionally raise blood pressure, so check your readings regularly if you have high blood pressure.
  • Limit alcohol use: Avoid drinking alcohol while taking this medicine, as the combination significantly increases your risk of developing stomach ulcers or bleeding.
  • Watch for signs of bleeding: Be alert for unusual bruising, nosebleeds, or pink-tinged urine, and report these to your doctor immediately.
  • Inform healthcare providers: Let your dentist or surgeon know you are taking Brufen 400 Tablet 20's before any upcoming procedures, as it can slightly affect blood clotting.
  • Seek medical advice before use if needed: Talk to your doctor before taking Brufen 400 Tablet 20's if you are pregnant, elderly, have kidney disease, stomach ulcers, heart disease, high blood pressure, asthma, or a history of gastrointestinal bleeding, as closer monitoring or alternative treatment may be required. 

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with Brufen 400 Tablet 20's: 

  • Blood thinners (like warfarin): May increase the risk of severe stomach bleeding and bruising.
  • Other pain relievers (like aspirin or naproxen): Taking these together increases the likelihood of stomach irritation and ulcers.
  • Blood pressure medications (like ACE inhibitors or water pills): Brufen 400 Tablet 20's can decrease the effectiveness of these medicines and increase strain on the kidneys.
  • Lithium: May increase lithium levels in your blood, raising the risk of toxicity.
  • Methotrexate: Taking Brufen 400 Tablet 20's with methotrexate may increase methotrexate levels in the body and raise the risk of serious side effects, including liver, kidney, or blood-related toxicity. Extra monitoring may be required. 
IbuprofenMeloxicam
Critical
IbuprofenKetorolac
Critical

Drug-Drug Interactions

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IbuprofenMeloxicam
Critical
How does the drug interact with Brufen 400 Tablet:
Combining Meloxicam and Brufen 400 Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Meloxicam and Brufen 400 Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenKetorolac
Critical
How does the drug interact with Brufen 400 Tablet:
Taking Ketorolac and Brufen 400 Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac and Brufen 400 Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenAminolevulinic acid
Severe
How does the drug interact with Brufen 400 Tablet:
The combined use of Aminolevulinic acid and Brufen 400 Tablet can increase the risk of severe sunburn.

How to manage the interaction:
Using Aminolevulinic acid and Brufen 400 Tablet together can lead to an interaction, they can be taken together if advised by your doctor. After treatment, avoid exposing your eyes and skin to sunlight or bright interior lights for 48 hours. Do not stop using any medications without a doctor's advice.
IbuprofenTeriflunomide
Severe
How does the drug interact with Brufen 400 Tablet:
The combined use of Teriflunomide and Brufen 400 Tablet can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Brufen 400 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light- colored stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenTinzaparin
Severe
How does the drug interact with Brufen 400 Tablet:
The combined use of Tinzaparin and Brufen 400 Tablet can increase the risk of bleeding complications.

How to manage the interaction:
Co-administration of Tinzaparin and Brufen 400 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenMetrizamide
Severe
How does the drug interact with Brufen 400 Tablet:
The combined use of Metrizamide and Brufen 400 Tablet can cause kidney damage.

How to manage the interaction:
Co-administration of Metrizamide and Brufen 400 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, irregular heart rhythm, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenHuman immunoglobulin
Severe
How does the drug interact with Brufen 400 Tablet:
Taking Human immunoglobulin with Brufen 400 Tablet may raise the risk of kidney problems.

How to manage the interaction:
Co-administration of Human immunoglobulin with Brufen 400 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
IbuprofenPhenylbutazone
Severe
How does the drug interact with Brufen 400 Tablet:
The combined use of Phenylbutazone and Brufen 400 Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Co-administration of Phenylbutazone and Brufen 400 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenIndometacin
Severe
How does the drug interact with Brufen 400 Tablet:
The combined use of Indometacin and Brufen 400 Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Indometacin and Brufen 400 Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenPrasugrel
Severe
How does the drug interact with Brufen 400 Tablet:
Co-administration of Prasugrel and Brufen 400 Tablet can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Prasugrel and Brufen 400 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Combining alcohol with this medicine significantly raises the risk of stomach ulcers and gastrointestinal bleeding.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Brufen 400 Tablet 20's is used to relieve mild to moderate pain, inflammation, and fever
Brufen 400 Tablet 20's works by blocking the effect of chemical messengers (prostaglandin), thereby reducing pain and inflammation.
Diarrhoea or dehydration might be a side-effect of Brufen 400 Tablet 20's. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Do not take Brufen 400 Tablet 20's for more than 10 days unless prescribed by your doctor. Taking Brufen 400 Tablet 20's for longer durations or high doses may cause a heart attack or stroke. Do not exceed the dose and duration prescribed by your doctor.
Brufen 400 Tablet 20's may increase the risk of heart attack or stroke. Therefore, consult your doctor before taking Brufen 400 Tablet 20's if you have heart problems. Do not use Brufen 400 Tablet 20's immediately before or after bypass surgery like CABG.
Taking Brufen 400 Tablet 20's with or after food or milk may partially reduce stomach side effects such as indigestion.
Brufen 400 Tablet 20's can be used for relieving period pain and cramps if prescribed by the doctor. Do not exceed the dose and duration prescribed by your doctor.
No, you should not take Brufen 400 Tablet 20's during pregnancy especially during late pregnancy, like other NSAIDs, as it may cause premature closure of the ductus arteriosus (a blood vessel that connects fetal pulmonary artery to aorta before birth and closes after birth). However if you have concerns consult your doctor.
Yes, Brufen 400 Tablet 20's can cause stomach pain. It is a common side effect of Brufen 400 Tablet 20's. To reduce the risk of stomach discomfort, it's recommended to take the Brufen 400 Tablet 20's with food or milk. If you experience persistent or severe stomach pain, it's important to consult doctor for advice.
Yes, Brufen 400 Tablet 20's can be effective in treating headaches. However, it's important to follow the dosage instructions on the packaging and consult with your doctor if you have any underlying health conditions or are taking other medications.
You should take Brufen 400 Tablet 20's exactly as prescribed by the doctor. Do not exceed the recommended dosage as this could result in an overdose.
Brufen 400 Tablet 20's is generally considered safe when used as directed by your doctor. However do not exceed recommended daily dosage.
If you forgot to take a dose of Brufen 400 Tablet 20's, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not take the double the dose as this can increase the risk of side effects.
If Brufen 400 Tablet 20's is prescribed for short term, it can be discontinued when the pain is relieved. However, it's always a good idea to follow your doctor's advice regarding the duration of use, especially if you have been prescribed a specific course of treatment.
Yes, Brufen 400 Tablet 20's can cause nausea and vomiting in some people as these are the side effects of Brufen 400 Tablet 20's. To help reduce the risk of these side effects, it's recommended to take the tablet with food or milk. If you experience persistent or severe nausea and vomiting, it's important to consult your doctor for advice.
Brufen 400 Tablet 20's is contraindicated in patients with known hypersensitivity to Ibuprofen, and in patients with urticaria, asthma, or allergic reactions after taking aspirin or NSAIDs. Also, it should not be used for treating perioperative pain during coronary artery bypass graft (CABG) surgery. It's important to discuss your medical history with your doctor before taking the Brufen 400 Tablet 20's to avoid potential interactions.
Brufen 400 Tablet 20's is generally not recommended for relieving stomach pain, if you're experiencing stomach pain, it's best to consult your doctor.
Yes, Brufen 400 Tablet 20's can cause kidney damage, especially with long-term use or in higher doses. Brufen 400 Tablet 20's can reduce blood flow to the kidneys, which may lead to acute kidney injury. Symptoms of kidney damage can include producing less urine, swelling in the arms, legs, or feet, and nausea. If these symptoms persist or worsen, please consult your doctor.
Yes, Brufen 400 Tablet 20's can cause dizziness in some people. This is a less common side effect, but it can happen. If you experience dizziness, it's a good idea to sit or lie down until you feel better and avoid activities that require full alertness. If dizziness persists for long time, consult your doctor.
The common side effects of Brufen 400 Tablet 20's are indigestion, diarrhoea, constipation, flatulence (gas), nausea, rash, weakness, dizziness. If these side effects persist or worsen, please consult your doctor.
You are recommended to avoid alcohol consumption while taking Brufen 400 Tablet 20's. Alcohol intake, along with Brufen 400 Tablet 20's may increase drowsiness and raise the risk of bleeding and stomach ulcers.
It is best to take Brufen 400 Tablet 20's with food or milk to prevent stomach upset. Taking it on an empty stomach can increase your risk of heartburn or irritation. If stomach pain persists, talk to your doctor.
For pain and fever, Brufen 400 Tablet 20's typically starts working within 30 to 60 minutes after you take it. For chronic inflammatory conditions, it may take a few days of consistent use to notice full benefits. If you do not feel relief, talk to your doctor.
No, Brufen 400 Tablet 20's does not typically cause drowsiness. However, in rare cases, some people might experience dizziness or fatigue. If you feel dizzy, avoid driving or operating machinery, and talk to your doctor.
Yes, in many cases, healthcare providers may allow you to alternate or combine Brufen 400 Tablet 20's with paracetamol because they work differently. However, you must ensure you do not exceed the recommended daily doses of either medication. Talk to your doctor.
If Brufen 400 Tablet 20's causes mild stomach discomfort, try taking it with food, milk, or an antacid. If the pain is severe, persistent, or accompanied by dark stools, stop taking it immediately and talk to your doctor
Yes, Brufen 400 Tablet 20's can cause mild fluid retention, which may lead to an increase in blood pressure, especially in individuals who already have high blood pressure. If you have hypertension, you should monitor your readings regularly while taking this medication. Talk to your doctor.
Frequent use of Brufen 400 Tablet 20's for headaches may increase the risk of medication-overuse headaches, stomach problems, kidney issues, and other side effects. If you need pain relief regularly, consult your doctor to identify the underlying cause and discuss safer long-term treatment options.
Brufen 400 Tablet 20's may be used in children over 6 months of age when recommended by a healthcare professional. The dose is usually based on the child's weight and age. Always use an appropriate paediatric formulation and measuring device, and consult your doctor or pharmacist before giving Brufen 400 Tablet 20's to children, especially those under 12 years of age.

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Reference

  1. Electronic Medicines Compendium (EMC). Pil.9406 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. U.S. Food and Drug Administration (FDA). 017463S105Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  3. National Health Service (NHS). Ibuprofen For Adults - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Ibuprofen Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Ulramol Soluble - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 23 August 2021]Check here
  6. Anadin Ibuprofen 200 mg tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 23 August 2021]Check here
  7. Derry, Christopher J et al. Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain. [Revised in 24th Jun 2013] . [Accessed on 10th February 2026]Check here

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi Dl 110034 INDIA
Other Info - BRU0204

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