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Drug-Drug Interactions
Drug-Drug Interactions
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Co-administration of Gemcal Capsule may lower the effectiveness of Patiromer calcium in binding potassium.
How to manage the interaction:
Although there is an interaction, Gemcal Capsule can be taken with Patiromer calcium if prescribed by the doctor. Consult the prescriber if you experience symptoms such as metabolic alkalosis like nausea, vomiting, tremor, muscle twitching, lightheadedness, numbness or tingling, prolonged muscle spasms, slowed breathing, irregular heartbeat, and confusion. Do not discontinue the medication without a doctor's advice.
Co-administration of Gemcal Capsule and Digoxin may increase the calcium levels may increase the effects of Digoxin
How to manage the interaction:
Although there is an interaction, Gemcal Capsule can be taken with Digoxin if prescribed by the doctor. Do not discontinue the medication without consulting a doctor.
Co-administration of Gemcal Capsule may interfere with the absorption of Raltegravir and reduce its effectiveness.
How to manage the interaction:
Taking Gemcal Capsule with Raltegravir should be avoided. Consult the doctor if you have any concerns, the doctor may recommend alternatives that do not interact with raltegravir. Do not discontinue the medication without consulting a doctor.
Co-administration of Dolutegravir with Gemcal Capsule can reduce the effectiveness of dolutegravir.
How to manage the interaction:
Although there is an interaction, Gemcal Capsule can be taken with dolutegravir if prescribed by the doctor. However, dolutegravir and Gemcal Capsule should not be taken orally at the same time. Maintain a gap of 2-6 hours between both medicines. Do not discontinue using any medications without consulting a doctor.
Co-administration of Gemcal Capsule may interfere with the absorption of Gefitinib and reduce its effectiveness.
How to manage the interaction:
Although there is an interaction, Gemcal Capsule can be taken with Gefitinib if prescribed by the doctor. However, Gefitinib and Gemcal Capsule should not be taken orally at the same time. Maintain a gap of 2-6 hours between both medicines. Do not discontinue using any medications without consulting a doctor.
Co-administration of Gemcal Capsule with Ketoconazole may decrease the effects of Ketoconazole.
How to manage the interaction:
Although there is an interaction, Gemcal Capsule can be taken with Ketoconazole if prescribed by the doctor. However, maintain a gap of 2 or more hours between both medicines. Do not discontinue the medication without consulting a doctor.
Coadministration of dolutegravir with Gemcal Capsule can reduce the efficacy of dolutegravir.
How to manage the interaction:
Although taking Dolutegravir and Gemcal Capsule together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take dolutegravir either two hours before or six hours after taking a dose of Gemcal Capsule. Do not discontinue using any medications without consulting a doctor.
Cholecalciferol and dihydrotachysterol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.
How to manage the interaction:
Although there is a possible interaction between Gemcal Capsule and dihydrotachysterol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Cholecalciferol and doxercalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.
How to manage the interaction:
Although there is a possible interaction between Gemcal Capsule and doxercalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Co-administration of Cholecalciferol and Calcitriol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.
How to manage the interaction:
Although there is a possible interaction between Gemcal Capsule and calcitriol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Spinach
How to manage the interaction:
Taking Gemcal Capsule with food containing oxalic acid (spinach or rhubarb) or phytic acid results in decreased absorption of Gemcal Capsule. It is advised to take Gemcal Capsule two hours before or after consumption of food containing oxalic acid or phytic acid.
Product Substitutes
Alcohol
Caution
Drinking alcohol can affect calcium absorption; hence it is advised to limit the alcohol intake while using Gemcal Capsule .
Pregnancy
Caution
During pregnancy, use higher doses of Gemcal Capsule than the daily dietary allowance only when advised by the doctor. Calcitriol in higher doses may harm the fetus. Your doctor will weigh the potential risks and benefits before recommending Gemcal Capsule .
Breast Feeding
Caution
Consult your doctor before taking Gemcal Capsule if you are breastfeeding. Gemcal Capsule can pass into the breast milk. If Gemcal Capsule is used during breastfeeding, please monitor the mother and the infant's serum calcium levels.
Driving
Caution
No interaction was found/established.
Liver
Caution
Let your doctor know if you have any history of liver diseases before taking Gemcal Capsule . Hepatic impairment/liver disease can alter the metabolic and therapeutic activity of certain Vitamin D forms.
Kidney
Caution
It is advised to seek doctor advice before starting Gemcal Capsule if you have kidney diseases like kidney stones or undergoing dialysis. Calcitriol in Gemcal Capsule increases inorganic phosphate levels in serum; hence caution should be taken in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition).
Children
Caution
Gemcal Capsule should be used with caution in children and only if recommended by a doctor.
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