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Ketoff Lotion 60 ml

Ketoff Lotion is used to prevent fungal infections of the skin like seborrheic dermatitis (dry, flaky skin on face, scalp, chest, upper back or ears). It works by damaging the fungal cell membranes and killing fungi, thereby slowing the growth of dandruff on the scalp. Some people may experience side effects such as itching, redness, irritation or a burning sensation at the site of application.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

KETOCONAZOLE-2%W/V+ZINC PYRITHIONE-1%W/V

Manufacturer/Marketer :

Eskon Pharma

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Ketoff Lotion

Ketoff Lotion is a topical medication prescribed to treat fungal skin and scalp conditions, such as seborrhoeic dermatitis, severe dandruff, and pityriasis versicolour. It works by targeting the overgrowth of yeast on the skin that leads to flaking, irritation, and redness. By addressing the root cause, it helps restore the natural balance of your skin and scalp.

For best results, you should use this medication consistently and exactly as directed by your healthcare provider, which is typically a few times a week or daily for a set period. To support your treatment, try to wash your hair and skin soon after heavy sweating and wear breathable, loose-fitting clothing. Since this is a topical product, it does not need to be taken with food, but ensuring the application area is clean and dry before use is essential.

Most people tolerate this treatment very well, though some may experience mild local irritation, burning, or redness at the application site. If you experience severe burning, swelling, or signs of a serious allergic reaction, stop using the product immediately and contact your doctor.

Talk to your doctor before starting this medicine if you have open wounds, severely broken skin, or sensitive skin conditions like eczema in the application area. Do not use this product if you have a known allergy to any of its active or inactive ingredients.

While topical products have very low absorption into the bloodstream, you should still inform your doctor about other skin treatments you are using, especially topical steroids, to avoid skin thinning or irritation. If you are pregnant, breastfeeding, or planning a pregnancy, consult your doctor or pharmacist before starting treatment to ensure it is safe for you.

Uses of Ketoff Lotion

Ketoff Lotion is used to treat fungal skin and scalp conditions and pityriasis versicolour. The detailed uses of Ketoff Lotion are as follows:

  • Seborrhoeic dermatitis: Ketoff Lotion helps treat this inflammatory skin condition by targeting the yeast responsible for causing red, greasy, and scaly patches on the scalp, face, and upper body.
  • Dandruff: Ketoff Lotion relieves chronic scalp flaking and itching by controlling yeast levels and regulating skin cell turnover.
  • Pityriasis versicolour: Ketoff Lotion treats this fungal infection, which causes discoloured patches on the chest, back, neck, or arms, by clearing the underlying fungal overgrowth.
     

Key Benefits

Ketoff Lotion provides targeted support to help manage fungal scalp and skin conditions, reducing the discomfort caused by persistent itching, flaking, redness, and irritation. By acting directly against the fungi responsible for these symptoms, this medicine offers several key benefits:

  • Helps Relieve Itching and Flaking: Ketoff Lotion works to reduce the fungal growth that contributes to dandruff, scaling, and irritation. As the infection improves, itching and visible flaking gradually decrease, helping restore comfort and confidence.
  • Supports Healthy Skin and Scalp Recovery: By reducing the yeast population on the skin and scalp, this medicine helps soothe redness, inflammation, and irritation. This supports the natural healing process and promotes a healthier skin barrier.
  • Helps Maintain Long-Term Scalp and Skin Health: With regular and appropriate use, Ketoff Lotion helps control the underlying fungal overgrowth associated with recurrent dandruff and scaly skin conditions, supporting clearer and healthier-looking skin and scalp over time.
     

Directions for Use

Always use Ketoff Lotion exactly as prescribed by your doctor or as detailed on the product packaging. The application steps vary slightly depending on whether you are using a cream, lotion, gel, or solution.

  • For Liquid, Solution, or Lotion (Scalp application): Wet your hair and scalp thoroughly. Apply a small amount of the product to the affected areas, massage gently to form a lather, and leave it on for 3 to 5 minutes before rinsing completely with water.
  • For Cream or Gel (Skin application): Clean and thoroughly dry the affected skin. Apply a thin layer of the cream or gel to the area and rub it in gently. Wash your hands immediately after application unless your hands are the treated area.
  • General Note: Avoid contact with your eyes, nose, or mouth. If accidental contact occurs, rinse thoroughly with cool water right away.

     

How Ketoff Lotion Works

Ketoff Lotion combines two highly effective active ingredients that work together to combat fungal skin issues from two different angles. The first active ingredient works by disrupting the cell membranes of the fungi and yeast, such as Malassezia, which effectively stops them from growing and reproducing. The second active ingredient acts as a cytostatic agent, meaning it slows down the rapid production of skin cells on your scalp. This dual action not only eliminates the fungus causing the irritation but also drastically reduces the peeling, flaking, and scaling of the skin, bringing your scalp back to its normal, healthy cycle.
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Alcohol

Consult your doctor

The interaction of Ketoff Lotion with alcohol is unknown. Please consult a doctor before consuming alcohol while using Ketoff Lotion.

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Pregnancy

Caution

Ketoff Lotion is a Category C pregnancy drug and is given to a pregnant woman only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether Ketoff Lotion is excreted in human milk. Please consult a doctor before using Ketoff Lotion while breastfeeding.

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Driving

Safe if prescribed

Ketoff Lotion usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

If you have any concerns regarding the use of Ketoff Lotion in patients with liver problems, please consult a doctor.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Ketoff Lotion in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Ketoff Lotion is not recommended for children below 12 years as the safety and effectiveness have not been established.

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Heart

Consult your doctor

Please consult your doctor before using Ketoff Lotion if you have pre-existing heart problems. Your doctor will prescribe Ketoff Lotion if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before giving Ketoff Lotion to geriatric patients. Your doctor will prescribe Ketoff Lotion if the benefits outweigh the risks.

What if I have taken an overdose of Ketoff Lotion

Do not apply Ketoff Lotion in large amounts or use it for a longer time than recommended, as it does not give quick or better results but increases the risk of side effects.

Diet & Lifestyle Advise

  • Keep the scalp dry: Fungi thrive in warm, damp environments. Ensure your hair and scalp are thoroughly dried after washing, especially before going to bed.
  • Avoid sharing personal items: Do not share combs, hairbrushes, towels, or hats with others, as this can spread fungal spores.
  • Manage stress levels: High stress can weaken your immune system and trigger flare-ups of seborrhoeic dermatitis and dandruff. Practice relaxation techniques like yoga or deep breathing.
  • Limit styling products: Reduce the use of heavy hair gels, sprays, and waxes, as they can trap oil and yeast on the scalp, worsening flaking.
  • Wash sweat away quickly: Cleanse your scalp and skin promptly after working out or sweating heavily to prevent yeast overgrowth.
     

Have a query?

How Soon It Starts Working

  • The time required for Ketoff Lotion to start to work: The time required for Ketoff Lotion to show its action is unknown.
  • The time for which the effects of Ketoff Lotion last: The duration of action for Ketoff Lotion is unknown.

Storage

•Store Ketoff Lotion at room temperature, ideally between 15°C and 30°C. Do not freeze the product, and keep it away from direct heat, sunlight, and moisture. •Store the container tightly closed in its original packaging.

What if you forget to take Ketoff Lotion

If you miss a dose of Ketoff Lotion, apply it as soon as you remember. If it is almost time for the next dose, skip the missed dose and apply the next dose at the regular time. Do not apply a double dose to make up for a missed one.

Drug Warnings

  • Avoid eye contact: This medication is strictly for external use. Keep it away from your eyes, eyelids, nose, and mouth.
  • Check the product colour and texture: Do not use Ketoff Lotion if you notice any unusual changes in its colour, consistency, or smell.
  • Do not cover the treated area: Unless specifically instructed by your doctor, do not cover the treated skin with tight bandages or airtight dressings.
  • Protect coloured or permed hair: Be aware that this product can occasionally alter the texture or colour of chemically treated hair; rinse very thoroughly after use.
  • Do not apply to broken skin: Avoid applying this product to open wounds, deep cuts, or severely raw skin unless your doctor advises otherwise.
     

Drug-Drug Interactions

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Drug-Drug Interactions

  • Topical Corticosteroids: If you have been using a strong topical steroid cream on your skin or scalp, talk to your doctor before starting Ketoff Lotion. Stopping a steroid suddenly can cause a flare-up of your skin condition, so your doctor may advise gradually reducing the steroid dose while starting Ketoff Lotion.

Drug-Disease Interactions

  • Severe skin barrier damage: If you have severe skin breakdown, open sores, or active skin infections, using Ketoff Lotion may cause intense irritation or increased absorption into your body. Talk to your doctor before applying.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIFUNGALS]

FAQs

Ketoff Lotion is primarily used to treat fungal infections of the skin like seborrheic dermatitis (dry, flaky skin on face, scalp, chest, upper back or ears).
Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close, direct contact until the infection is cleared and refrain from sharing items with the infected person, as this can also spread the infection.
After using Ketoff Lotion, wait for at least 20 minutes before applying makeup or sunscreen to the treated area of skin.
Yes, you may be advised to stop using other products containing steroids, such as hydrocortisone or betamethasone, before using Ketoff Lotion. However, inform your doctor if you are using any steroidal creams or lotions before using Ketoff Lotion, so the dose of steroidal cream can be gradually reduced to avoid flaring up the condition while using Ketoff Lotion.
It is recommended that you use Ketoff Lotion for as long as your doctor has prescribed it. However, if the condition persists or worsens after 2 to 4 weeks of treatment with Ketoff Lotion, please consult a doctor.
No, you are not recommended to stop using Ketoff Lotion without consulting your doctor, as it may cause recurring infections. Therefore, take Ketoff Lotion for as long as your doctor has prescribed it, and if you experience any difficulty while taking it, please consult your doctor.
No, Ketoff Lotion does not cure seborrheic dermatitis. However, treatment with Ketoff Lotion can control and reduce the symptoms of seborrheic dermatitis.
Many patients notice a reduction in itching, flaking, and irritation within a few applications. However, it may take 2 to 4 weeks of consistent use to achieve full improvement. Use Ketoff Lotion exactly as prescribed and do not apply it more frequently than recommended, as this may increase the risk of side effects without improving results faster. Consult your doctor if your symptoms do not improve or worsen.
The safety and effectiveness of Ketoff Lotion in children have not been fully established, particularly in children below 12 years of age. Do not use Ketoff Lotion in children unless recommended by a doctor or paediatrician.
Yes, you can use it, but only if recommended by your doctor. Before making a recommendation, your doctor will check for potential interactions between them and suggest alternatives if necessary.
Common side effects of Ketoff Lotion may include itching, redness, irritation or a burning sensation at the application site. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Yes, but only if directed by your doctor. If you are treating seborrhoeic dermatitis on your face, apply it carefully to avoid getting the product in your eyes, nose, or mouth. Talk to your doctor for advice.
Yes. You can use your regular non-medicated shampoo to wash your hair on the days you are not using Ketoff Lotion. If you use conditioner, apply it only to the ends of your hair to avoid build-up on the scalp. Talk to your doctor or pharmacist.
Because this product is applied topically, very little of it enters your bloodstream. However, you should always consult your doctor or pharmacist before using any medicated product during pregnancy.
Hair loss is highly uncommon with this medication. In rare cases, changes in hair texture or mild hair shedding can occur, but this is often related to the underlying scalp inflammation itself rather than the medicine. Talk to your doctor if you have concerns.
In some cases, the active ingredients can cause discolouration or change the texture of chemically treated, coloured, or permed hair. Make sure to rinse your hair thoroughly after each use. Talk to your doctor or pharmacist if you notice changes.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Nizoral Ketoconazole 2 Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  2. Drugs.com Clinical Review Team. Pyrithione Zinc Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  3. DailyMed Database. Druginfo.Cfm Clinical Monograph. Bethesda, MD: National Library of Medicine; 2025. [Accessed on 02 Jun. 2026] Check here
  4. Pinewood Healthcare. Ketoconazole 2% w/w Shampoo – Summary of Product Characteristics [Internet]. Dublin: Pinewood Healthcare; [Accessed on 2025 Sep 17] Check here
  5. Daily med. Pyrithione zinc shampoo. [Revised in November 2021] [Accessed on 21st April 2026] Check here
  6. Central Drugs Standard Control Organization (CDSCO). List of New Drugs Approved in the Year 2025 Till Date [Internet]. New Delhi: CDSCO; [Accessed on 2025 Sep 17] Check here
  7. Alkem Laboratories Ltd. Dandrop Shampoo 2% (Ketoconazole & Zinc Pyrithione) – Product Information [Internet]. Mumbai: Alkem Laboratories Ltd.; [Accessed on 2025 Sep 17]Check here

Country of origin

India

Manufacturer/Marketer address

5/3/3b, Anjal Nagar 4th Cross Street, Koodal Nagar, Maduari, Pin - 625 018.
Other Info - KET0196

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