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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MACROGOL SACHET is used to treat constipation. It works by drawing water into the intestine, which softens the stools, making them easier to pass. In some cases, this medicine may cause side effects such as stomach pain, indigestion, mild diarrhoea, nausea, or vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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About MACROGOL SACHET

MACROGOL SACHET belongs to a class of drugs called laxatives, used to treat constipation. Constipation refers to infrequent bowel movements in which the stools are often dry, painful, and hard to pass.

MACROGOL SACHET contains Polyethylene glycol, Potassium chloride, Sodium bicarbonate, and Sodium chloride. MACROGOL SACHET works by drawing water into the intestine, softening stools, and making them easier to pass. It also helps replenish electrolytes.

In some cases, you may experience stomach pain, indigestion, mild diarrhoea, nausea, or vomiting. Most of these side effects of MACROGOL SACHET do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to MACROGOL SACHET or any other medicines, please tell your doctor. MACROGOL SACHET is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please consult a doctor before taking MACROGOL SACHET.

Uses of MACROGOL SACHET

MACROGOL SACHET is used in the treatment of Constipation. The detailed uses of MACROGOL SACHET are as follows:

  • Constipation relief: MACROGOL SACHET helps retain water in the colon to soften stools and ease bowel movements.
  • Bowel cleansing: MACROGOL SACHET used before medical procedures like colonoscopy to effectively clear the intestines.

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Directions for Use

  • MACROGOL SACHET can be taken with or without food, or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Check the label for directions. Dilute MACROGOL SACHET with water as advised by your doctor. Take it orally using the measuring cup provided with the package.
  • Shake the bottle well before each use.

Key Benefits

  • MACROGOL SACHET is a combination of Polyethylene glycol, Potassium chloride, Sodium bicarbonate, and Sodium chloride. It is primarily used to relieve constipation and promote comfortable bowel movements.
  • Polyethylene glycol works by drawing water into the intestines, softening the stools, and cleansing the gastrointestinal tract, making stool passage easier.
  • Potassium chloride supports the healthy functioning of muscles, nerves, and organs, maintaining electrolyte balance.
  • Sodium bicarbonate helps neutralise excess stomach acid, providing relief from acidity, bloating, and heartburn.
  • Sodium chloride aids in maintaining proper sodium and fluid balance in the body.
  • MACROGOL SACHET helps in softening stools, easing bowel movements, restoring electrolyte balance, and relieving constipation effectively.

How MACROGOL SACHET Works

MACROGOL SACHET is a combination of four drugs, namely Polyethylene glycol, Potassium chloride, Sodium bicarbonate, and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools, making them easier to pass. Potassium chloride is essential for the healthy functioning of organs. Sodium bicarbonate works by neutralising high levels of acid in the stomach, helping to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, MACROGOL SACHET helps in relieving constipation.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of MACROGOL SACHET

Take MACROGOL SACHET only as advised by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are allergic to MACROGOL SACHET or any other medicines, please tell your doctor.
  • If you have ulcerative colitis or Crohn’s disease, inform your doctor before taking MACROGOL SACHET.
  • MACROGOL SACHET is not recommended for children below 12 years of age.
  • If you are pregnant or breastfeeding, please consult a doctor before taking MACROGOL SACHET.
  • Drink plenty of fluids while taking MACROGOL SACHET.
  • Do not take MACROGOL SACHET in more than the recommended doses.
  • Discard MACROGOL SACHET after 30 days of first opening the bottle.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Macrogol Sachet 14gm:
Taking Darifenacin with Macrogol Sachet 14gm(oral capsule or tablet) can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Darifenacin with Macrogol Sachet 14gm(oral capsule or tablet) is not recommended, as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not stop taking any medications without doctor's advise.
How does the drug interact with Macrogol Sachet 14gm:
Taking Solifenacin and Macrogol Sachet 14gm together can increase the risk of stomach ulcers, bleeding, and stomach injury.

How to manage the interaction:
Taking Solifenacin with Macrogol Sachet 14gm is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Macrogol Sachet 14gm:
Using Eplerenone together with Macrogol Sachet 14gm may significantly increase potassium levels in the blood.

How to manage the interaction:
Taking Macrogol Sachet 14gm with eplerenone is not recommended. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat, consult the doctor immediately. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Biperiden with Macrogol Sachet 14gm can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Biperiden with Macrogol Sachet 14gm is not recommended as it can lead to an interaction, but can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Macrogol Sachet 14gm:
Taking Procyclidine and Macrogol Sachet 14gm together can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Procyclidine with Macrogol Sachet 14gm is not recommended, but it can be taken together if advised by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Mepenzolate and Macrogol Sachet 14gm(in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Mepenzolate with Macrogol Sachet 14gm is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
How does the drug interact with Macrogol Sachet 14gm:
Taking Clemastine and Macrogol Sachet 14gm(in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Clemastine with Macrogol Sachet 14gm is not recommended, as it can lead to an interaction, can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
How does the drug interact with Macrogol Sachet 14gm:
Taking Tolterodine and Macrogol Sachet 14gm together can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tolterodine and Macrogol Sachet 14gm, they can be taken if prescribed by a doctor. However, contact a doctor immediately if you develop severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), or less desire to eat. Do not discontinue medications without consulting a doctor.
Potassium chlorideclidinium bromide
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Macrogol Sachet 14gm with clidinium bromide may increase the risk of irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Co-administration of Macrogol Sachet 14gm with clidinium bromide is not recommended, it can be taken if prescribed by the doctor. However, if you experience symptoms such as severe stomach pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), decreased hunger, black, tarry stools, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macrogol Sachet 14gm:
Taking Olanzapine with Macrogol Sachet 14gm can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Co-administration of Olanzapine and Macrogol Sachet 14gm is not recommended as it leads to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try maintaining a balanced diet, which includes fresh fruits and vegetables.
  • Stay hydrated by drinking enough water and fluids.
  • Exercise regularly, and stay fit.
  • Get enough sleep.
  • Eat food rich in fibre, such as whole-wheat bread, oatmeal, flaxseed, nuts, beans, lentils, fruits (berries, apples, oranges, bananas, pears, figs), and vegetables (broccoli, spinach, sweet potatoes, avocados).

Habit Forming

No

Therapeutic Class

[LAXATIVES]

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Alcohol

Safe if prescribed

The interaction of alcohol with MACROGOL SACHET is unknown. Please consult a doctor before consuming alcohol while using MACROGOL SACHET.

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Pregnancy

Consult your doctor

Please consult a doctor if you are pregnant. MACROGOL SACHET is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Please consult a doctor if you are breastfeeding. MACROGOL SACHET is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.

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Driving

Safe if prescribed

MACROGOL SACHET usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Take MACROGOL SACHET with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Consult your doctor

Take MACROGOL SACHET with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Safe if prescribed

MACROGOL SACHET is not recommended for children under 12 years of age, as its safety and effectiveness have not been established.

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Heart

MACROGOL SACHET should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking MACROGOL SACHET.

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Geriatrics

Consult your doctor

MACROGOL SACHET should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using MACROGOL SACHET.

FAQs

MACROGOL SACHET belongs to a class of drugs called laxatives, used to treat constipation.

MACROGOL SACHET contains Polyethylene glycol, Potassium chloride, Sodium bicarbonate and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools, making it easier to pass. Potassium chloride is essential for the healthy functioning of organs. Sodium bicarbonate works by neutralising high levels of acid in the stomach, helping to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, MACROGOL SACHET helps in relieving constipation.

MACROGOL SACHET may cause mild diarrhoea as a side effect at the beginning of the treatment. It usually gets better by reducing the amount of MACROGOL SACHET intake. However, if the condition persists or worsens, please consult a doctor.

You are not recommended to take MACROGOL SACHET with anticonvulsants as it may reduce the effectiveness of anticonvulsants (medicines for epilepsy). However, please consult your doctor before taking MACROGOL SACHET with other medicines.

You are recommended to avoid foods that are high in fat and low in fibre, such as ice cream, red meat, frozen meals, potato chips, cheese, hot dogs and hamburgers.

You are not recommended to take more than the advised dose of MACROGOL SACHET as it may cause excessive diarrhoea that might lead to dehydration. If you have diarrhoea, stop taking MACROGOL SACHET and drink plenty of fluids to avoid dehydration. However, if the condition persists or worsens, please consult a doctor.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Other Info - MAC0064

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