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Pegclear Oral Solution is used to treat chronic constipation and faecal impaction in children. It works by drawing water into the intestine, softening stools, and making them easier to pass. It may cause side effects like stomach pain, diarrhoea, nausea, or vomiting. Let your doctor know if your child is taking any other medicines or has pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

About Pegclear Oral Solution

This medicine is designed specifically to help children pass stool easily without pain or straining. It is typically given once or several times a day depending on the severity of your child's constipation.

To get the best results, give this medicine consistently at the same time each day, with or without food. Alongside this treatment, simple everyday changes, like encouraging your child to drink more water and eat high-fiber foods, can greatly improve their progress.

While taking Pegclear Oral Solution , some children may experience mild side effects like a rumbling tummy, gas, or mild bloating. These are usually harmless, but if your child develops severe watery diarrhoea, persistent vomiting, or extreme tiredness, stop giving the medicine and contact your doctor right away. Keeping your doctor informed helps ensure your child stays safe and comfortable throughout their treatment.

Talk to your doctor before starting this medicine if your child has any underlying medical conditions, especially severe stomach or heart issues. Do not give this medicine if your child has a torn bowel wall, a complete blockage in their intestines, or severe inflammatory bowel diseases. Your paediatrician will help determine if this is the safest option for your child.

Because this oral solution works by moving waste through the gut, it may temporarily affect how your child's body absorbs other oral medicines. It is best to give other oral medicines at least one to two hours before or after giving this solution. Always consult your paediatrician or pharmacist if your child is taking any other suggested or over-the-counter treatments.

Uses of Pegclear Oral Solution

Pegclear Oral Solution is used in the treatment of constipation in children. The detailed use of Pegclear Oral Solution is as follows:

  • Paediatric constipation: Helps soften hard, dry stool so your child can have regular, pain-free bowel movements.
  • Faecal impaction: Helps clear severe, long-term blockages of hardened stool that have built up in your child's bowel.
     

Key Benefits

Pegclear Oral Solution helps relieve constipation in children by softening stools and supporting hydration during bowel movements.

The following are the benefits of this medication:

  • Provides gentle and predictable relief from uncomfortable constipation.
  • Softens stools, reducing pain and straining during bowel movements.
  • Helps break the cycle of stool holding and supports the return of natural bowel habits.
  • Helps maintain proper hydration in the digestive tract.
  • Helps prevent the loss of vital body salts while clearing the bowels.
  • Helps children feel more comfortable and active.
Side effects of Pegclear Oral Solution 200 ml
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Pegclear Oral Solution should be given to your child with or without food.
  • Follow your doctor's instructions on the dosage and timing of this medication, or use it as per the labelled instructions.
  • Dissolve the contents of the sachet in a quarter glass of water to form a solution, and give it to your child to drink.
  • If your child cannot drink it immediately, store the reconstituted solution in the refrigerator (2°C to 8°C).
  • Discard the solution if not used within 24 hours.

How Pegclear Oral Solution Works

This oral solution contains four active ingredients that work through a highly effective, dual-action process in your child's digestive system. It softens the stool to manage constipation and provides salts to help your child's body maintain its natural fluid and mineral balance. Polyethylene glycol: It acts as an osmotic agent, which means it naturally holds water in the bowel. Instead of being absorbed by the body, this water stays in the stool, gently soaking and softening hard blockages so they can pass more easily Potassium chloride: It helps maintain normal potassium levels in the body while the medicine helps clear the bowel. Sodium bicarbonate: It helps maintain the body's normal fluid and mineral balance during treatment. Sodium chloride: It helps replace sodium and maintain the body's normal fluid balance while the bowel is being cleared.
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Alcohol

Not applicable

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

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Driving

Not applicable

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Liver

Consult your doctor

If your child has liver disease, inform your doctor before using Pegclear Oral Solution .

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Kidney

Consult your doctor

If your child has kidney disease, inform your doctor before using Pegclear Oral Solution .

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Children

Safe if suggested

Pegclear Oral Solution should be used for children in dose and duration as the doctor advises.

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Heart

Caution

Please inform your doctor before giving Pegclear Oral Solution to your child if they have heart problems, as the electrolytes may affect fluid balance and heart function. Medical supervision ensures safe use and helps avoid complications like electrolyte disturbances.

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Geriatrics

Not applicable

Pegclear Oral Solution is specifically for children use and is not meant for geriatric patients.

What if I have taken an overdose of Pegclear Oral Solution

If your child takes much more of this solution than suggested, they may experience severe diarrhoea and vomiting, which can lead to dehydration. Seek immediate medical attention or contact your local emergency health service right away.

Diet & Lifestyle Advise

  • Increase fluid intake: Ensure your child drinks plenty of water throughout the day to help the medicine soften the stool more effectively.
  • Offer fibre-rich foods: Incorporate fruits like pears, plums, and apples, along with vegetables and whole grains, into your child's daily meals.
  • Create a toilet routine: Encourage your child to sit on the toilet for 5 to 10 minutes after meals, especially after breakfast, to help establish regular habits.
  • Encourage active play: Regular physical activity helps stimulate the natural movement of your child's digestive system.
     

Health Queries

My child has been taking Pegclear for 10 days to treat irregular bowel movements and hard stools. Since long-term use of laxatives is generally not recommended, what are the safe medical alternatives or next steps to manage pediatric constipation?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

It is reassuring to know that polyethylene glycol is highly safe and often prescribed for weeks or even months under medical guidance to help the bowel recover its natural tone. To manage transition, the best next steps involve dietary and lifestyle changes: gradually increase fiber intake (via fruits, vegetables, and whole grains), ensure plenty of water daily, and establish a regular toilet routine after meals. Safe medical alternatives include osmotic laxatives like lactulose or dietary fiber supplements. Please consult your pediatrician before making any changes; they can guide a safe, gradual tapering process to prevent recurrence of constipation.
health query

Have a query?

How Soon It Starts Working

The time required for Pegclear Oral Solution to start to work: The time required for Pegclear Oral Solution to show its action is not clinically established.

The time for which the effects of Pegclear Oral Solution last: The duration of action for Pegclear Oral Solution is not clinically established.

Storage

• Store the unopened bottle or dry powder pack at room temperature, below 25°C, away from direct heat and moisture.

What if you forget to take Pegclear Oral Solution

If you forget to give a dose, give it as soon as you remember. If it is almost time for the next scheduled dose, skip the missed one and continue with your regular schedule. Do not give a double dose to make up for a missed one.

Drug Warnings

  • Check the solution before use: Make sure the solution is clear, colourless, and free from floating particles. Do not use it if it looks cloudy, changes colour, or contains particles.
  • Measure the dose carefully: Use the measuring device provided or a proper medical measuring device to give your child the correct dose. Do not use a regular household spoon.
  • Watch for dehydration: Look for signs such as crying without tears, dry lips or mouth, or urinating less often than usual. Contact your child’s doctor if you notice these signs.
  • Avoid other laxatives: Do not give your child other laxatives while using this medicine unless your paediatrician specifically tells you to do so.

Drug-Drug Interactions

verifiedApollotooltip
  • This solution may speed up your child's digestive system, which can reduce the absorption of other medicines taken by mouth. Give other oral medications at least 1 to 2 hours before or after giving this medicine.
     
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chloridePhenindamine
Critical
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideEplerenone
Critical

Drug-Drug Interactions

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Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chloridePhenindamine
Critical
How does the drug interact with Pegclear Oral Solution 200 ml:
Taking Pegclear Oral Solution 200 ml together with Phenindamine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Pegclear Oral Solution 200 ml together with Phenindamine is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideEplerenone
Critical
How does the drug interact with Pegclear Oral Solution 200 ml:
Using Pegclear Oral Solution 200 ml together with Eplerenone may significantly increase potassium levels in the blood.

How to manage the interaction:
Taking Pegclear Oral Solution 200 ml with eplerenone is not recommended. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideOrphenadrine (citrate)
Critical
How does the drug interact with Pegclear Oral Solution 200 ml:
Taking Pegclear Oral Solution 200 ml with Orphenadrine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Pegclear Oral Solution 200 ml with Orphenadrine is not recommended, as it can lead to an interaction, can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult a doctor immediately.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideBiperiden
Critical
How does the drug interact with Pegclear Oral Solution 200 ml:
Co- administration of Pegclear Oral Solution 200 ml with Amitriptyline may cause stomach and upper intestinal discomfort.

How to manage the interaction:
Taking Pegclear Oral Solution 200 ml with Biperiden is not recommended as it can lead to an interaction, but can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideTrospium
Critical
How does the drug interact with Pegclear Oral Solution 200 ml:
Taking Pegclear Oral Solution 200 ml with Trospium can increase the risk of stomach ulcers and bleeding

How to manage the interaction:
Taking Pegclear Oral Solution 200 ml with Trospium is not recommended as it may lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideTolterodine
Critical
How does the drug interact with Pegclear Oral Solution 200 ml:
Taking Pegclear Oral Solution 200 ml together with Tolterodine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Pegclear Oral Solution 200 ml together with Tolterodine is not recommended, as it can lead to an interaction, they can be taken if prescribed by a doctor. However, contact a doctor immediately if you develop severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), or loss of appetite. Do not discontinue medications without consulting a doctor.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideSolifenacin
Critical
How does the drug interact with Pegclear Oral Solution 200 ml:
Taking Pegclear Oral Solution 200 ml together with Solifenacin can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Pegclear Oral Solution 200 ml with Solifenacin is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideDoxepin
Critical
How does the drug interact with Pegclear Oral Solution 200 ml:
Taking Doxepin with Pegclear Oral Solution 200 ml with doxepin can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Pegclear Oral Solution 200 ml with Doxepin is not recommended, as it can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), loss of appetite, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideOxybutynin
Critical
How does the drug interact with Pegclear Oral Solution 200 ml:
Co-administration of Pegclear Oral Solution 200 ml with Oxybutynin can increase the risk of developing stomach ulcers and bleeding.

How to manage the interaction:
Taking Pegclear Oral Solution 200 ml with Oxybutynin is not recommended, as it can lead to an interaction, it can be taken when a doctor has prescribed it. Consult a doctor immediately if you experience severe stomach pain, bloating, lightheadedness, dizziness, vomiting (especially with blood), decreased hunger, or dark stools. Do not discontinue any medication without contacting a doctor.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideDicyclomine
Critical
How does the drug interact with Pegclear Oral Solution 200 ml:
Co-administration of Pegclear Oral Solution 200 ml with Dicyclomine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Pegclear Oral Solution 200 ml with Dicyclomine is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult a doctor immediately. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically relevant food or drink interactions have been found.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Pegclear Oral Solution is used to treat constipation. It helps children to have a comfortable bowel movement even if they have been constipated for a long time.
Pegclear Oral Solution contains Polyethylene glycol, Potassium chloride, Sodium bicarbonate and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools, making it easier to pass. Potassium chloride is essential for healthy organ functioning. Sodium bicarbonate works by suppressing high levels of acid in the stomach and helps to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, Pegclear Oral Solution helps in relieving constipation.
Pegclear Oral Solution may cause diarrhoea as a side effect at the beginning of the treatment. It usually gets better when the dose is reduced. However, if the condition persists or worsens, please consult a doctor.
It is recommended to avoid foods that are high in fat and low in fibre, such as ice cream, red meat, frozen meals, potato chips, cheese, hot dogs and hamburgers.
You are not recommended to give more than the advised dose of Pegclear Oral Solution as it may cause excessive diarrhoea that might lead to dehydration. If your child has diarrhoea, stop giving Pegclear Oral Solution and let them drink plenty of fluids to avoid dehydration. However, if the condition persists or worsens, please consult a doctor.
It is best to mix and give this solution with plain water as directed on the packaging. Talk to your doctor or pharmacist before mixing it with other drinks.
If your child develops loose, watery stools, reduce the dose or stop giving the medicine and contact your paediatrician for advice. Talk to your doctor to adjust the treatment safely.
This medicine can be used for longer periods if suggested by a paediatrician, but you should not give it for extended times without regular medical supervision. Talk to your doctor about your child's treatment plan.
Some children may experience mild stomach grumbling or light cramps when they first start taking it, but this usually stops quickly. If the pain is severe or persistent, talk to your doctor.
Yes, you can mix the solution in advance, but you must keep it in a sealed container in the refrigerator and use it within 24 hours. Talk to your pharmacist if you need more storage advice.
If your child vomits shortly after taking a dose, do not immediately give another dose. Wait for their tummy to settle and consult your paediatrician on how to proceed. Talk to your doctor if vomiting continues.
Most formulations of this oral solution do not contain added sugars, making them safe for children who need to limit sugar intake. Talk to your doctor or pharmacist to confirm the exact ingredients of your specific product.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Office No. 5119, 5th Floor, 'D' Wing, Oberoi Garden Estates, Chandivili, Andheri (E), Mumbai - 400 072.
Other Info - PEG0065

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