ACEBROPHYLLINE+ACETYLCYSTEINE belongs to the class of drugs called ‘mucolytic agents’ (cough/sputum thinner) primarily used to prevent and treat symptoms of chronic obstructive pulmonary disease (COPD) such as shortness of breath, coughing, or wheezing (whistling sound while breathing). COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).
ACEBROPHYLLINE+ACETYLCYSTEINE is a combination of two drugs, namely: Acebrophylline (mucolytic and bronchodilator) and Acetylcysteine (mucolytic agent/sputum thinner). Acebrophylline belongs to the class of bronchodilators with additional mucolytic properties and works by relaxing muscles and widening the airways of the lungs. Acetylcysteine belongs to the class of mucolytic agents (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. ACEBROPHYLLINE+ACETYLCYSTEINE breakdown the acid mucopolysaccharide fibers that make the mucus (sputum) thinner and less dense/viscous removing sputum efficiently by coughing. However, the viscosity of sputum remains low for as long as treatment is maintained. Together, they help to cough out easily and make breathing easier by opening airways.
Take ACEBROPHYLLINE+ACETYLCYSTEINE as prescribed. Your doctor will recommend how often you take ACEBROPHYLLINE+ACETYLCYSTEINE based on your medical condition. Some people may experience diarrhoea, nausea, vomiting, runny nose, dizziness, heartburn, stomach pain, skin rash, drowsiness, and cool and moist skin. Most of these side effects of ACEBROPHYLLINE+ACETYLCYSTEINE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to ACEBROPHYLLINE+ACETYLCYSTEINE or any other medicines, please tell your doctor. ACEBROPHYLLINE+ACETYLCYSTEINE is not recommended for children below 14 years of age. Drink plenty of fluids to thin mucus and lubricate your throat while taking ACEBROPHYLLINE+ACETYLCYSTEINE. ACEBROPHYLLINE+ACETYLCYSTEINE is not recommended for use during pregnancy. If you are breastfeeding, it is advised to inform your doctor before taking ACEBROPHYLLINE+ACETYLCYSTEINE. Severe skin reactions such as Stevens-Johnson syndrome (a serious and rare disorder of skin and mucus membranes) or toxic epidermal necrolysis (skin blistering or skin peeling) have been rarely reported in some patients. However, if you notice any skin rash worsening with mucosal lesions or blisters, stop taking ACEBROPHYLLINE+ACETYLCYSTEINE and contact your doctor immediately. Do not take ACEBROPHYLLINE+ACETYLCYSTEINE if you have a heart rhythm disorder that causes fast heartbeats. Avoid taking ACEBROPHYLLINE+ACETYLCYSTEINE if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), had a heart attack, or kidney or liver diseases. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, asthma, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, or kidney or liver insufficiency, inform your doctor before taking ACEBROPHYLLINE+ACETYLCYSTEINE.
Chronic obstructive pulmonary disease (COPD)
ACEBROPHYLLINE+ACETYLCYSTEINE is a combination of two drugs, namely: Acebrophylline and Acetylcysteine. Acebrophylline belongs to the class of bronchodilators with additional mucolytic properties and works by relaxing muscles and widening the airways of the lungs. Acetylcysteine is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. ACEBROPHYLLINE+ACETYLCYSTEINE breakdown the acid mucopolysaccharide fibers that make the mucus (sputum) thinner and less dense/viscous removing sputum efficiently by coughing. However, the viscosity of sputum remains low for as long as treatment is maintained. Together, they help to cough out easily and make breathing easier by opening airways.
If you are allergic to ACEBROPHYLLINE+ACETYLCYSTEINE or any other medicines, please tell your doctor. ACEBROPHYLLINE+ACETYLCYSTEINE is not recommended for children below 14 years of age. Regular monitoring of potassium levels is recommended while taking ACEBROPHYLLINE+ACETYLCYSTEINE as it may cause low potassium levels in the blood. ACEBROPHYLLINE+ACETYLCYSTEINE is not recommended for use during pregnancy. If you are breastfeeding, it is advised to inform your doctor before taking ACEBROPHYLLINE+ACETYLCYSTEINE. Severe skin reactions such as Stevens-Johnson syndrome (a serious and rare disorder of skin and mucus membranes) or toxic epidermal necrolysis (skin blistering or skin peeling) have been rarely reported in some patients. However, if you notice any skin rash worsening with mucosal lesions or blisters, stop taking ACEBROPHYLLINE+ACETYLCYSTEINE and contact your doctor immediately. Do not take ACEBROPHYLLINE+ACETYLCYSTEINE if you have heart rhythm disorder that causes fast heartbeats. Avoid taking ACEBROPHYLLINE+ACETYLCYSTEINE if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), had a heart attack, or kidney or liver diseases. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, asthma, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, or kidney or liver insufficiency, inform your doctor before taking ACEBROPHYLLINE+ACETYLCYSTEINE.
Drug-Drug Interaction: ACEBROPHYLLINE+ACETYLCYSTEINE may interact with water pills (furosemide), medicines used to treat gout (allopurinol), antacid (cimetidine), antibiotics (ciprofloxacin, erythromycin, amoxicillin, doxycycline, tetracycline, gentamicin, amikacin, neomycin), drugs used to lower high blood pressure (diltiazem, verapamil), heart-related medicines (isoprenaline), anthelmintic (thiabendazole), corticosteroids (prednisone), oral contraceptives (ethinylestradiol), medicines used to treat chest pain (glyceryl trinitrate) and cough suppressants (dextromethorphan, codeine).
Drug-Food Interaction: If you are allergic to histamine, avoid histamine-rich foods such as tomatoes, wine, and processed foods as it may cause histamine intolerance leading to symptoms such as flushing (redness of the skin), migraine headaches, skin rash, itching, and rhinitis (runny and stuffy nose). Also, avoid intake of alcohol with ACEBROPHYLLINE+ACETYLCYSTEINE as it may increase drowsiness. Also, avoid or limit the intake of caffeine with ACEBROPHYLLINE+ACETYLCYSTEINE as it may cause side effects.
Drug-Disease Interaction: Avoid taking ACEBROPHYLLINE+ACETYLCYSTEINE if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), had a heart attack, or kidney or liver diseases. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, asthma, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, or kidney or liver insufficiency, inform your doctor before taking ACEBROPHYLLINE+ACETYLCYSTEINE.
Avoid consumption of alcohol with ACEBROPHYLLINE+ACETYLCYSTEINE as it may reduce the effectiveness of ACEBROPHYLLINE+ACETYLCYSTEINE and increase drowsiness. Please consult a doctor before consuming alcohol with ACEBROPHYLLINE+ACETYLCYSTEINE.
ACEBROPHYLLINE+ACETYLCYSTEINE is not recommended for pregnant women. Please consult a doctor before using ACEBROPHYLLINE+ACETYLCYSTEINE if you are pregnant.
It is unknown whether ACEBROPHYLLINE+ACETYLCYSTEINE is excreted in human milk. Please consult a doctor before taking ACEBROPHYLLINE+ACETYLCYSTEINE if you are breastfeeding.
ACEBROPHYLLINE+ACETYLCYSTEINE usually does not affect your ability to drive or operate machinery.
Take ACEBROPHYLLINE+ACETYLCYSTEINE with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Take ACEBROPHYLLINE+ACETYLCYSTEINE with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
ACEBROPHYLLINE+ACETYLCYSTEINE is not recommended for children below 14 years of age. Please consult a doctor before giving ACEBROPHYLLINE+ACETYLCYSTEINE to children.
Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).