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About ISOXSUPRINE HYDROCHLORIDE

ISOXSUPRINE HYDROCHLORIDE belongs to a class of medication called 'vasodilators' (blood vessel relaxing agents) used to treat and prevent peripheral vascular diseases such as Raynaud's phenomenon, cerebral vascular insufficiency (poor blood flow to the brain), arteriosclerosis (hardening of the arteries), Buerger's disease (a condition that causes small and medium arteries and veins to constrict blood flow to the hands and feet) and other conditions involving poor blood flow in the blood vessels. Besides this, it is also used for relaxing uterine muscles to prevent premature labour.

ISOXSUPRINE HYDROCHLORIDE contains Isoxsuprine hydrochloride, which acts by relaxing and widening the blood vessels, thereby improving blood circulation. Thus, it helps to treat peripheral vascular diseases. ISOXSUPRINE HYDROCHLORIDE relaxes and prevents the contractions of smooth muscles of the uterus, thereby preventing premature labour.

ISOXSUPRINE HYDROCHLORIDE should be taken regularly in dose and duration as advised by the doctor. In some cases, ISOXSUPRINE HYDROCHLORIDE may cause dizziness, irregular heartbeat, nausea, vomiting, and weakness. Most of these side effects of ISOXSUPRINE HYDROCHLORIDE do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

ISOXSUPRINE HYDROCHLORIDE should not be stopped abruptly without consulting the doctor as it may lead to unpleasant side effects. Inform your doctor before starting ISOXSUPRINE HYDROCHLORIDE if you have any bleeding disorder or heart problem. ISOXSUPRINE HYDROCHLORIDE may cause a sudden fall in blood pressure, so be cautious if you are driving, operating a motor vehicle or doing any hazardous task. Do not stand suddenly from a lying position as you may feel dizzy. Avoid alcohol intake with ISOXSUPRINE HYDROCHLORIDE as it may cause dizziness.

Uses of ISOXSUPRINE HYDROCHLORIDE

Peripheral vascular diseases, Prevention of premature labour

Medicinal Benefits

ISOXSUPRINE HYDROCHLORIDE contains Isoxsuprine hydrochloride, which is a vasodilator. It is used in the treatment of cerebrovascular insufficiency (poor blood flow to the brain), peripheral vascular disease (blocked veins of the leg), Buerger's disease (blood clot in arm and legs) and Raynaud's disease (numb and cold sensation due to blocked nerves of hand). ISOXSUPRINE HYDROCHLORIDE acts by relaxing and widening the blood vessels, thereby improving blood circulation. Thus, it helps to treat peripheral vascular diseases. ISOXSUPRINE HYDROCHLORIDE relaxes and prevents the contractions of smooth muscles of the uterus, thereby preventing premature labour.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ISOXSUPRINE HYDROCHLORIDE

  • Weakness
  • Dizziness
  • Flushing
  • Stomach upset
  • Vomiting

In-Depth Precautions and Warning

Drug Warnings

Inform your doctor if you are allergic to any of the components, have low blood pressure (less than 90 mm of Hg), have had a heart problem, or bleeding problem. Tell your doctor that you are using ISOXSUPRINE HYDROCHLORIDE before undergoing any dental or other surgery. Your doctor might stop this medicine before the surgery. ISOXSUPRINE HYDROCHLORIDE should not be stopped abruptly without consulting the doctor as it may lead to unpleasant side effects. Also, lifestyle changes should be continued with ISOXSUPRINE HYDROCHLORIDE for best results and a speedy recovery. ISOXSUPRINE HYDROCHLORIDE may cause dizziness, so if you are sitting, rise slowly to avoid falling and be cautious while driving or operating machinery.

Drug Interactions

Drug-Drug Interaction: No interactions found/established.

Drug-Food Interaction: No interactions found/established.

Drug-Disease Interaction: ISOXSUPRINE HYDROCHLORIDE should be taken with caution in people who have low blood pressure, a bleeding problem, especially arterial bleeding, have had a heart attack or any heart problem.

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    caution

    Avoid alcohol consumption with ISOXSUPRINE HYDROCHLORIDE as it might cause increased dizziness.

  • Safety Warning

    Pregnancy

    caution

    Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

  • Safety Warning

    Breast Feeding

    caution

    Consult your doctor, and there is no substantial research yet on the use of ISOXSUPRINE HYDROCHLORIDE in breastfeeding/nursing mothers.

  • Safety Warning

    Driving

    caution

    Drive with caution, ISOXSUPRINE HYDROCHLORIDE may cause blurry vision and dizziness.

  • Safety Warning

    Liver

    caution

    There is limited information available on the use of ISOXSUPRINE HYDROCHLORIDE in patients with liver disease. Please consult your doctor for the best advice.

  • Safety Warning

    Kidney

    caution

    There is limited information available on the use of ISOXSUPRINE HYDROCHLORIDE in patients with kidney disease. Please consult your doctor for the best advice.

  • Safety Warning

    Children

    unsafe

    ISOXSUPRINE HYDROCHLORIDE is not recommended for children as the safety and effectiveness of ISOXSUPRINE HYDROCHLORIDE have not been established.

Habit Forming

No

Diet & Lifestyle Advise

  • Opt for a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid stress. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Reduce intake of fatty food, sugar and salt.
  • Limit or avoid alcohol consumption.
  • Strenuous exercise or work should be avoided to avoid delivery complications.

Special Advise

  • Use caution while driving a motor vehicle, operating machinery, or performing other hazardous activities as, ISOXSUPRINE HYDROCHLORIDE may cause dizziness. If you experience dizziness or drowsiness, avoid these activities. Try to rise slowly from a sitting or lying position to avoid falling.
  • Notify your doctor if you experience any skin rash or palpitation (irregular heartbeats) after using ISOXSUPRINE HYDROCHLORIDE.

Patients Concern

Disease/Condition Glossary

Premature labour: It is also known as preterm labour which occurs due to contractions and relaxations of the uterus resulting in the opening of the cervix after week 20 and before week 37 of pregnancy. It can lead to premature birth and other risks to the baby.

Cerebrovascular insufficiency: It occurs when there is obstruction of one or more blood vessels (arteries) that supply blood to the brain. This obstruction leads to strokes or transient ischemic attacks (TIAs or 'mini-strokes').

Buerger's disease: It occurs commonly in the arms and legs where blood vessels get swollen, thereby preventing blood flow, causing clots to form. This leads to pain, tissue damage, and the formation of gangrene (death of body tissues).

Raynaud's phenomenon: It occurs due to blocked nerves resulting in discolouration of the fingers and/or the toes after exposure to extreme cold or hot temperatures conditions. Skin discolouration is a sign of a diminished blood supply to the local tissues.

FAQs

How does ISOXSUPRINE HYDROCHLORIDE work?

ISOXSUPRINE HYDROCHLORIDE acts by relaxing and widening blood vessels, thereby increasing the blood flow to the organs, muscles and blocked nerves of the body.

I need to undergo dental surgery. Do I need to inform my doctor?

If you are taking ISOXSUPRINE HYDROCHLORIDE and are due to undergo dental surgery, please inform your doctor. Your doctor may advise you to stop taking ISOXSUPRINE HYDROCHLORIDE before the surgery.

What should I do if I forget a dose?

If you forget to take ISOXSUPRINE HYDROCHLORIDE at any time, take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose. Do not take a double dose to make up for a forgotten dose.

Does ISOXSUPRINE HYDROCHLORIDE cause orthostatic hypotension?

Orthostatic hypotension could be a side-effect of ISOXSUPRINE HYDROCHLORIDE. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking ISOXSUPRINE HYDROCHLORIDE are advised to regularly monitor their blood pressure levels to avoid unpleasant events.

Can I stop using ISOXSUPRINE HYDROCHLORIDE on my own?

Please do not stop taking ISOXSUPRINE HYDROCHLORIDE without consulting your doctor as it may lead to unpleasant effects. Continue taking ISOXSUPRINE HYDROCHLORIDE for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking ISOXSUPRINE HYDROCHLORIDE.

Available Medicines for

ISOXSUPRINE HYDROCHLORIDE