If you are allergic to polmacoxib, aspirin, or other non-steroidal anti-inflammatory drugs, please tell your doctor. POLMACOXIB is not recommended for pregnant or breastfeeding women. POLMACOXIB should be used with caution in patients with diabetes, bronchial asthma, high blood pressure, cardiovascular disease, history of oedema, peptic ulcer or gastrointestinal bleeding. Patients with uncontrolled high blood pressure should avoid taking POLMACOXIB as it may worsen the condition. If you have slurred speech, chest pain, weakness, or shortness of breath while taking POLMACOXIB, consult a doctor immediately, as these might be symptoms of cardiovascular toxicity. Elderly patients should use POLMACOXIB with caution as they may be at greater risk for serious gastrointestinal adverse effects such as intestinal or gastric bleeding, perforation and ulceration.

Drug-Drug Interaction: Inform your doctor if you are taking blood thinners (warfarin), antifungal (ketoconazole), corticosteroids, immunosuppressants (tacrolimus, cyclosporine), antimetabolite (methotrexate), antimanic agent (lithium), aspirin or other NSAIDs. POLMACOXIB should be used cautiously in patients taking diuretics (furosemide, thiazide diuretics) or ACE inhibitors (medicines used to lower high blood pressure).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: Avoid taking POLMACOXIB if you have a history of asthma, acute rhinitis, nasal polyps, angioedema, urticaria, have uncontrolled high blood pressure, oedema or fluid retention, liver or kidney impairment, active peptic ulcer or gastrointestinal bleeding, Crohn's disease or ulcerative colitis, congestive heart failure, ischemic heart disease, peripheral arterial disease, and/or cerebrovascular disease, high potassium levels in the blood or blood coagulation disorders.

• Maintain a healthy body weight, as obesity may cause joint pains. Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.
• Include more glucosamine, chondroitin sulfate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
• In the chronic conditions of arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids, which help reduce inflammation (redness and swelling).
• Your sitting posture is important, especially when you have pain and inflammation conditions. Try to sit as little as possible, and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Besides this, you can use a footrest if required.