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About S ADENOSYL L METHIONINE

S ADENOSYL L METHIONINE is used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression. Alcoholic liver disease occurs due to liver damage because of excessive alcohol consumption. Osteoarthritis is a condition in which the joints are affected. Depression is a mood disorder and a psychological, physiological and emotional experience that affects the way we think, the things we do and the way we act.

S ADENOSYL L METHIONINE contains S-Adenosyl-L-Methionine, an essential amino acid required for optimal cellular functioning. S ADENOSYL L METHIONINE is believed to monitor and regulate important physiological functions in living cells. It increases glutathione concentration and metabolism of the liver. S ADENOSYL L METHIONINE increases chondrocyte proteoglycan synthesis, thereby helping treat osteoarthritis.

S ADENOSYL L METHIONINE may be taken with or without food, but it is better to take it at a designated time. S ADENOSYL L METHIONINE should be swallowed whole and not crushed or chewed. In some cases, S ADENOSYL L METHIONINE may cause certain common side effects such as nausea, diarrhoea, stomach pain, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of the components of S ADENOSYL L METHIONINE. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Exercise caution when taking S ADENOSYL L METHIONINE with any anti-Parkinsonian drugs or anti-depressants. It is not advisable to take alcohol with S ADENOSYL L METHIONINE as there may be an interaction. Discuss your entire surgical history with your treating doctor and keep them informed of any pending surgical procedure.

Uses of S ADENOSYL L METHIONINE

Liver disease, osteoarthritis, depression.

Medicinal Benefits

S ADENOSYL L METHIONINE contains S-Adenosyl-L-Methionine. S ADENOSYL L METHIONINE helps in the synthesis of essential amino acid methionine, which is required for major body functions. It helps provide cellular energy and charge the living cells of various organs like the brain, bones and liver with stamina and fuel, thereby finding application in the treatment of depression, arthritis and liver disease. It helps in major detoxification of the liver in case of diseases caused by a retarded flow of bile such as intrahepatic cholestasis. S ADENOSYL L METHIONINE may also find use in the treatment of fibromyalgia, chronic pain, attention deficit hyperkinetic disorder and Alzheimer’s disease. However, studies to understand the mechanism behind the same have been inconclusive.

Directions for Use

Take S ADENOSYL L METHIONINE as directed by the physician. Swallow it whole with a glass of water. Do not crush, chew, or break it. S ADENOSYL L METHIONINE can be taken with or without food, but it is better to take it with food.

Storage

Store in a cool and dry place away from sunlight

Side Effects of S ADENOSYL L METHIONINE

  • Nausea

  • Diarrhoea

  • Flatulence

  • Stomach pain

In-Depth Precautions and Warning

Drug Warnings

It is advisable to inform the doctor if you are allergic to any of the components of S ADENOSYL L METHIONINE. Keep your doctor informed of your entire medical history before using S ADENOSYL L METHIONINE. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Exercise caution when taking S ADENOSYL L METHIONINE with any anti-Parkinsonian drugs or anti-depressants. It is not advisable to take S ADENOSYL L METHIONINE with alcohol as there may be an interaction. Discuss your entire surgical history with your treating doctor and keep them informed of any pending surgical procedure.

Drug Interactions

Drug-Drug Interactions: S ADENOSYL L METHIONINE may interact with antiparkinson drug (levodopa), antidepressants (fluoxetine, paroxetine, atomoxetine, citalopram, escitalopram, sertraline), antipsychotics (olanzapine, clozapine, risperidone), painkillers (tramadol, methadone, meperidine) and anti-migraine triptans (sumatriptan, zolmitriptan).

Drug-Food Interactions: No interactions were found.

Drug-Disease Interactions: S ADENOSYL L METHIONINE should be used with caution in patients with a known hypersensitivity disorder, mental health disorder, bipolar disorder and Parkinson’s disease. 

Drug-Drug Interactions Checker List:

  • LEVODOPA
  • FLUOXETINE
  • PAROXETINE
  • RISPERIDONE
  • OLANZAPINE
  • CITALOPRAM
  • ESCITALOPRAM
  • MEPERIDINE
  • TRAMADOL
  • METHADONE
  • SUMATRIPTAN
  • ZOLMITRIPTAN
  • SERTRALINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      It is not known whether it is safe to consume alcohol with S ADENOSYL L METHIONINE. Please consult your doctor if you have any concerns.

    • Safety Warning

      Pregnancy

      caution

      S ADENOSYL L METHIONINE should be used with caution in pregnant women. Please consult a doctor if you are pregnant.

    • Safety Warning

      Breast Feeding

      caution

      S ADENOSYL L METHIONINE should be used with caution in nursing mothers. Please consult a doctor.

    • Safety Warning

      Driving

      caution

      S ADENOSYL L METHIONINE may rarely cause drowsiness and dizziness. Exercise caution while driving in case of these side effects.

    • Safety Warning

      Liver

      consult your doctor

      S ADENOSYL L METHIONINE is possibly safe on the liver. Please consult your doctor in case of any concerns.

    • Safety Warning

      Kidney

      consult your doctor

      S ADENOSYL L METHIONINE is possibly safe on the kidney. Please consult your doctor in case of any concerns.

    • Safety Warning

      Children

      caution

      It is not established if S ADENOSYL L METHIONINE is safe to use in children. Please consult the treating doctor in case of any concerns.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Load up on lean meats, fatty fish, green leafy vegetables, fruits and nuts to enhance anti-oxidation and optimal functioning of the body.

    • Drink a lot of water and keep yourself hydrated.
    • Maintain a healthy weight by exercising for at least 30 minutes daily. 
    • Stop smoking as this can have a negative effect on the absorption of S ADENOSYL L METHIONINE and worsen the disease conditions.

    Special Advise

    Inform the doctor in case of any pending surgery or surgical procedure before taking S ADENOSYL L METHIONINE. 

    Patients Concern

    Disease/Condition Glossary

    Liver disease: Liver disease is a condition in which the liver does not function properly. Symptoms include severe skin itching, nausea, loss of appetite, jaundice, dark urine or stools etc. 

    Osteoarthritis: Osteoarthritis is the most common type of arthritis. It occurs due to the breakdown of cartilage that cushions and protects the bones. The disease progresses gradually and tends to worsen if not treated. Symptoms include joint pain in the hips, lower back, knees and hands.

    Depression: Depression is a psychological, physiological and emotional experience that affects the way we think, the things we do and the way we act. Losing interest in activities you once enjoyed, loss of appetite, feelings of guilt, low mood, low self-esteem and low energy levels are some symptoms of depression.

    FAQs

    S ADENOSYL L METHIONINE is used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression.
    Please see an orthopaedic doctor if you have had a fracture. S ADENOSYL L METHIONINE is used in the case of arthritis and has limited use in the treatment of fractures as a fracture is more of surgical concern.
    Yes, S ADENOSYL L METHIONINE finds a lot of benefit in treating depression. However, if you are on any anti-depressants, keep your doctor informed to avoid any interactions.
    In case you miss a dose of S ADENOSYL L METHIONINE, take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule.
    S ADENOSYL L METHIONINE is probably safe on the kidney; however, in case of CKD, it is best to consult your treating doctor before using S ADENOSYL L METHIONINE.
    S ADENOSYL L METHIONINE works by the synthesis of methionine, which is an essential amino acid required for cellular energy.

    Available Medicines for

    S ADENOSYL L METHIONINE

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