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Enapril-HT Tablet is used to treat hypertension (high blood pressure). It contains Enalapril and Hydrochlorothiazide, which decreases the constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Also, it removes excess water and certain salts such as sodium and potassium from the blood. This reduces the fluid volume circulating through blood vessels and lower high blood pressure. In some cases, you may experience dizziness, weakness, blurred vision, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), high cholesterol or uric acid levels, electrolyte imbalance, diarrhoea, chest pain, fast heartbeat, changes in taste or stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Enapril-HT Tablet
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Enapril-HT Tablet:
Using aliskiren together with Enapril-HT Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood.

How to manage the interaction:
Taking Enapril-HT Tablet with aliskiren is not recommended, but it can be taken together if your doctor advises. However, contact your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, or feelings of heaviness in the legs. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Enapril-HT Tablet:
Taking Cisapride and Enapril-HT Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Enapril-HT Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Critical
How does the drug interact with Enapril-HT Tablet:
Taking Dofetilide and Enapril-HT Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Enapril-HT Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Enapril-HT Tablet:
Coadministration of Allopurinol with Enapril-HT Tablet may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Allopurinol and Enapril-HT Tablet, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also, let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not stop using any medications without consulting your doctor.
How does the drug interact with Enapril-HT Tablet:
Due to additive or synergistic effects, coadministration of Enapril-HT Tablet with Irbesartan may raise the risk of hyperkalemia, hypotension, syncope, and renal failure. In severe cases, hyperkalemia can lead to muscle paralysis,kidney damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Enapril-HT Tablet together with Irbesartan may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Enapril-HT Tablet:
Due to additive or synergistic effects, coadministration of Enapril-HT Tablet with candesartan may raise the risk of hyperkalemia, hypotension, syncope, and renal failure. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Enapril-HT Tablet together with Candesartan may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilPotassium iodide
Severe
How does the drug interact with Enapril-HT Tablet:
Taking Enapril-HT Tablet with Potassium iodide increases the potassium levels in the blood, which may lead to hyperkalemia. In severe cases, hyperkalemia may lead to muscular paralysis, kidney damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Enapril-HT Tablet together with Potassium iodide may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, coconut and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilMipomersen
Severe
How does the drug interact with Enapril-HT Tablet:
When mipomersen is used with other drugs that can potentially damage the liver, like Enapril-HT Tablet, the risk of liver issues increases.

How to manage the interaction:
Although taking Enapril-HT Tablet and Mipomersen together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms - joint pain, swelling, skin rash, itching, fatigue, abdominal pain, or dark urine - immediately contact your doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Enapril-HT Tablet:
Enapril-HT Tablet combined with Trimethoprim can cause hyperkalemia by elevating blood potassium levels. In severe cases, hyperkalemia can induce muscle paralysis, renal damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of renal or cardiovascular disease.

How to manage the interaction:
Although taking Enapril-HT Tablet together with Trimethoprim may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Enapril-HT Tablet:
Using Enapril-HT Tablet together with Irbesartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Irbesartan with Enapril-HT Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, and feelings of heaviness in your legs. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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ENALAPRIL-10MG+HYDROCHLOROTHIAZIDE-25MGPotassium rich foods
Moderate

Drug-Food Interactions

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ENALAPRIL-10MG+HYDROCHLOROTHIAZIDE-25MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consumption of potassium rich food while on the treatment with Enapril-HT Tablet can lead to weakness, confusion, numbness of tingling sensation in hands or legs, or slow or rapid heartbeat. Avoid or limit consumption of potassium rich food while on the treatment with Enapril-HT Tablet.

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